Academic

 

Job Category

Faculty Non Bargaining

Job Title

Postdoctoral Research Fellow - Single Cell Genomics, drug resistance in cancer

 

Department

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine (Samuel Aparicio)

 

JOB DESCRIPTION:

Post-doctoral Fellow (PDF) Single Cell Genomics, drug resistance in cancer We are seeking a highly-motivated post-doctoral fellow (PDF) with strong leadership ability and expertise in single cell genomics and transcriptomics, and a strong background in molecular biology. The successful applicant will work full-time under the supervision of Dr. Samuel Aparicio on an exciting project decoding the role of epigenomic and genomic drug resistance. The position start date is flexible.

JOB SUMMARY:
The Aparicio lab is developing new single cell genome and transcriptome methods for tracking clonal trajectories at single cell level in patient tissues and patient-derived xenografts (PDX). The lab is highly multidisciplinary and highly productive (Laks et al, Cell 2019, Salehi et al Nature 2021, Funnell et al Nature 2022) and is well funded for single cell analysis of genomes and transcriptomes in cancer. The Aparicio lab is developing new single cell genome and transcriptome methods for tracking clonal trajectories at single cell level in patients and patient-derived xenografts. The project involves collaborating on an exciting project mapping clonal dynamics in human cancers under drug treatment with new single cell methods. The post holder will also have the opportunity to interact as part of the international Welcome LEAP Delta Tissue project and an exciting new program in the biology of epithelium from high risk carriers of BRCA1/BRCA2 mutations. These projects are bringing new measurement methods and computational techniques to the 3D reconstruction of tumours, and mapping drug sensitivity and drug combinations using sgRNA/CRISPR methods in vivo. The program works closely with UBC departments of statistics and computer science and the New York Genome Center NY, on the development of new models for single cell data and cancer evolution. Some experience with bioinformatics approaches to biological data and familiarity with handling of genomics data will be an advantage.

ORGANIZATIONAL STATUS:

Aparicio Lab is located in the department of Molecular Oncology at BC Cancer Research Center in Vancouver, British Columbia, Canada. The candidate will report directly to Dr. Samuel Aparicio, and will play a senior leadership role in the laboratory.

The Department of Pathology and Laboratory Medicine at UBC is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients.  The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence. 

WORK PERFORMED:
● Provide leadership, strategic direction, and translational research pertaining to single cell genomics and transcriptomics, and CRISPR methods.
● Design and implement research plan to investigate the clonal dynamics in human cancer through single cell methods.
● Design and conduct animal experiments.
● Conduct in vivo testing or characterization of drugs, small molecules, knockouts or antibodies in relevant PDX animal models.
● Foster research collaborations and work jointly with academic, clinical, industry, and other partners.
● Scientifically document lab experiments, data analysis, interpretations.
● Write manuscripts, present results at internal and external meetings.
● Identify funding opportunities and if required write or assist with grant proposals
● Lead and mentor junior trainees/students in the laboratory

CONSEQUENCE OF ERROR:
This is a senior research position that plays a critical role in the development of this novel field. PDF is accountable for the quality and integrity of the research and data, including analyses and interpretation, as well as the effective and efficient management of research projects and deliverables. This position requires innovation, strategic planning, and adaptability. Incorrect decisions or actions may damage the reputation of the laboratory, lead to loss of credibility in this field, and be financially costly.

SUPERVISION RECEIVED:

The PDF will work with a high degree of independence and set priorities under broad directives from Dr. Aparicio. The PDF will be expected to provide direction and mentoring in the laboratory under the supervision of Dr. Aparicio. This position will also provide the candidate with a high level of exposure to single cell genomics and translational research, as well as, providing opportunities to work collaboratively with industry partners and other researchers globally.

SUPERVISION GIVEN:

The PDF will be expected to provide mentorship and guidance to undergraduate, graduate students and other research members as required.

QUALIFICATION:
● Ph.D. in biology, cell biology, molecular biology, biochemistry, genetics, genomics, or similar discipline.
● The candidate should have a solid scientific and technical background with excellent written/oral communication, interpersonal and organizational skills.
● Preference will be given to candidates with a proven track record with a minimum of 2-3 first author publications in reputable journals.
● Proficiency in cell biology, molecular biology, histology, genetics, genomics, next-generation sequencing and biochemistry techniques.
● Demonstrate the ability to work in a highly interdisciplinary environment.
● Experience with cancer research.
● Expertise and hands-on experience in animal studies, including all aspects of design, handling, breeding, tissue collection, histology, and analyses are essential.
● Familiarity with testing/characterization of small molecule or drug in vivo is preferred.
● Previous biochemical/cell biology and molecular biology experience with single cell genomics / transcriptomics, next generation sequencing, drugs screen and PDX modeling is an asset.
● Experience with statistical analyses and scientific writing. Previous experience with grant writing is an asset.
● Experience with bioinformatics approaches to biological data and familiarity with handling of genomics data is an asset.
● Applicants with experience and a strong track record with large drug target screening, single cell methods, and PDX mouse models are especially encouraged to apply.

How to Apply:

Exceptional candidates should submit a cover letter outlining your research interests and fit with the laboratory's research, curriculum vitae, and the names of three referees willing to provide letters of reference.

Due to the number of resumes we receive, we are unable to confirm receipt of submissions over the phone, or provide the status of the competition. Only shortlisted candidates will be contacted.

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

UBC hires on the basis of merit and is committed to employment equity. All qualified persons are encouraged to apply.

Equity and diversity are essential to academic excellence.  An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged.  We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, and/or Indigenous person.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

The GSC is currently looking for a Research Associate to work on the Personalized OncoGenomics Program (POG). The goal of this program is to develop cutting-edge approaches to aid in the determination of relevant therapeutic options based on the genomic and transcriptomic information derived from a patient’s tumour. Working under the supervision of the Principal Investigator and the Group Leader, the successful incumbent will work with the project team to lead the activities on the development, implementation and performing bioinformatics analysis, as well as interpretation and communication of genomic data in a clinical context.

Duties include:

• Developing, implementing and performing bioinformatics and statistical analysis on human cancer data.
• Liaising with clinical staff to facilitate communication of informative or clinically actionable genomic results.
• Development and maintenance of  informatics resources that support the POG program.
• Providing scientific direction, leading data analysis and preparation of manuscripts and/or presentation of research papers.
• Performing literature review and identifying, collecting and analyzing internal and external datasets.
• Testing and implementing software for inclusion into research projects.
• Assisting in the preparation of grants, protocols and other funding related documents.

Skills and Abilities:

• PhD in molecular genetics, molecular biology, genomics, bioinformatics or related field.
• Broad understanding of human molecular genetics and cancer biology.
• Experience working with human genomic data, particularly next generation sequencing data (WGS, RNAseq).
• Proficiency in a common programming language (eg. Python or R).
• Excellent communication and organization skills, and ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
• Ability for critical thinking and independent learning.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RA_R00006_POG_2023_03_10 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options are available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

JOB DESCRIPTION:

Post-doctoral Fellow (PDF) G-quadruplex biology and therapeutics We are seeking a highly-motivated post-doctoral fellow (PDF) with strong leadership ability and expertise in molecular biology, single cell genomics and transcriptomics, and a background in DNA drug target biology in cancer. The successful applicant will work full-time under the supervision of Dr. Samuel Aparicio. The position start date is flexible.

JOB SUMMARY:

A postdoctoral/research fellow position is available, working on an exciting international project to define additional mechanisms and target engagement of G4 ligands in cancer genomes, utilizing single cell sequencing and chemical biology methods. The Aparicio lab is developing small molecule ligands of G-quadruplex structures in DNA as a therapeutic, based on recent success from the lab demonstrating for the first time clinical proof of principle (Hilton et al, Nat. Comms 2022) for a G4 binder. The Aparicio lab is multidisciplinary environment, highly productive (Laks et al, Cell 2019, Salehi et al Nature 2021, Funnell et al Nature 2022, aparicio.molonc.ca for projects and papers) and is well funded for single cell analysis of genomes and transcriptomes in cancer. The labs has created and practices methods for sequencing single genomes, defining epigenetic states in single cells and mapping gene fitness in vivo (Eirew et al, Nat. Comms 2022). The post holder will also have the opportunity to interact as part of the international Welcome LEAP Delta Tissue project and an exciting new program in the biology of epithelium from high risk carriers of BRCA1/BRCA2 mutations. The program works closely with UBC departments of statistics and computer science and the New York Genome Center NY, on the development of new models for single cell data and cancer evolution. Some experience with bioinformatics approaches to biological data and familiarity with handling of genomics data will be an advantage, beyond core experience of molecular biology and drug target biology in cancer.

ORGANIZATIONAL STATUS:

Aparicio Lab is located in the department of Molecular Oncology at BC Cancer Research Center in Vancouver, British Columbia, Canada. The candidate will report directly to Dr. Samuel Aparicio, and will play a senior leadership role in the laboratory.

The Department of Pathology and Laboratory Medicine at UBC is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients.  The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence. 

WORK PERFORMED:
● Provide leadership, strategic direction, and translational research pertaining to single cell genomics and transcriptomics, and CRISPR methods.
● Design and implement research plan to investigate the clonal dynamics in human cancer through single cell methods.
● Design and conduct animal experiments.
● Conduct in vivo testing or characterization of drugs, small molecules, knockouts or antibodies in relevant PDX animal models.
● Foster research collaborations and work jointly with academic, clinical, industry, and other partners.
● Scientifically document lab experiments, data analysis, interpretations.
● Write manuscripts, present results at internal and external meetings.
● Identify funding opportunities and if required write or assist with grant proposals
● Lead and mentor junior trainees/students in the laboratory

CONSEQUENCE OF ERROR:
This is a senior research position that plays a critical role in the development of this novel field. PDF is accountable for the quality and integrity of the research and data, including analyses and interpretation, as well as the effective and efficient management of research projects and deliverables. This position
requires innovation, strategic planning, and adaptability. Incorrect decisions or actions may damage the reputation of the laboratory, lead to loss of credibility in this field, and be financially costly.

SUPERVISION RECEIVED:

The PDF will work with a high degree of independence and set priorities under broad directives from Dr. Aparicio. The PDF will be expected to provide direction and mentoring in the laboratory under the supervision of Dr. Aparicio. This position will also provide the candidate with a high level of exposure to single cell genomics and translational research, as well as, providing opportunities to work collaboratively with industry partners and other researchers globally.

SUPERVISION GIVEN:

The PDF will be expected to provide mentorship and guidance to undergraduate, graduate students and other research members as required.

QUALIFICATIONS:
● Ph.D. in biology, cell biology, molecular biology, biochemistry, genetics, genomics, or similar discipline.
● The candidate should have a solid scientific and technical background with excellent written/oral communication, interpersonal and organizational skills.
● Preference will be given to candidates with a proven track record with a minimum of 2-3 first author publications in reputable journals.
● Proficiency in cell biology, molecular biology, histology, genetics, genomics, next-generation sequencing and biochemistry techniques.
● Demonstrate the ability to work in a highly interdisciplinary environment.
● Experience with cancer research.
● Expertise and hands-on experience in animal studies, including all aspects of design, handling, breeding, tissue collection, histology, and analyses are essential.
● Familiarity with testing/characterization of small molecule or drug in vivo is preferred.
● Previous biochemical/cell biology and molecular biology experience with single cell genomics / transcriptomics, next generation sequencing, drugs screen and PDX modeling is an asset.
● Experience with statistical analyses and scientific writing. Previous experience with grant writing is an asset.
● Experience with bioinformatics approaches to biological data and familiarity with handling of genomics data is an asset.
● Applicants with experience and a strong track record with large drug target screening, single cell methods, and PDX mouse models are especially encouraged to apply.

How to Apply:

Exceptional candidates should submit a cover letter outlining your research interests and fit with the laboratory's research, curriculum vitae, and the names of three referees willing to provide letters of reference.

Due to the number of resumes we receive, we are unable to confirm receipt of submissions over the phone, or provide the status of the competition. Only shortlisted candidates will be contacted.

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

UBC hires on the basis of merit and is committed to employment equity. All qualified persons are encouraged to apply.

Equity and diversity are essential to academic excellence.  An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged.  We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, and/or Indigenous person.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference Number: RP_R0008_Steif Lab_2023_02_23

We are looking for an outstanding research programmer with experience developing and applying computational workflows for high-throughput sequencing data analysis to join Dr. Adi Steif’s cancer genomics research group in Vancouver, Canada.

The successful applicant will be part of an exceptional multidisciplinary team of bioinformatic scientists and trainees, working alongside collaborators in biomedical engineering and molecular biology at the University of British Columbia. By joining the Steif Lab, you will help advance genomic technology alongside highly motivated specialists in a creative and dynamic environment. You will have access to robust high performance computing infrastructure and unique and complex single cell sequencing datasets, all while living in one of the most beautiful, diverse and eclectic cities in the world.

We offer a competitive salary, excellent benefits and significant career development opportunities.

Responsibilities

Working in a multidisciplinary team, the research programmer will develop and maintain analytical workflows for high-throughput cancer genomics. This is a one-year term appointment, with potential for renewal. Responsibilities include:

• Design and implement robust computational workflows
• Thoroughly test and maintain high-quality, well-documented code
• Regularly review the scientific literature to ensure analysis is in line with best practices
• Contribute to data preprocessing and quality control
• Develop data visualizations and contribute to biological analysis and interpretation
• Regularly update Dr. Steif, group members and collaborators on the status of projects
• Participate in and present research updates at lab meetings and team meetings
• Contribute to scientific writing, including the preparation of research manuscripts and grant applications
• May be involved in the management and supervision of trainees

Qualifications

• A B.Sc. or M.Sc. in bioinformatics, computer science, statistics or related discipline
• At least 3 years of experience in bioinformatics
• Experience in genomics and high-throughput sequencing data analysis
• Experience in cancer research is an asset
• Programming fluency in Python or R
• Experience working in a Unix/Linux computing environment
• Critical thinking and attention to detail
• Excellent verbal, written and interpersonal communication skills
• Ability to work independently and in a collaborative interdisciplinary team
• A strong work ethic, with demonstrated ability to manage time and prioritize to meet deadlines

Application

Applicants should submit: a CV; a one-page cover letter explaining how your research experience, interests and career goals align with the position; and the names and contact details of three references to bcgscjobs@bcgsc.ca, using Job Reference No: RP_R0008_Steif Lab_2023_02_23 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options are available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference Number: PDF_01553_Steif Lab_2023_02_23

This is an opportunity to advance single cell omics technology and work alongside highly motivated colleagues in a We are looking for an outstanding Postdoctoral Fellow with experience developing and applying computational methods for high-throughput omics analysis to join Dr. Adi Steif’s computational cancer genomics research group in Vancouver, Canada.

The successful applicant will be part of an exceptional multidisciplinary team of engineers, molecular biologists and bioinformatic scientists developing a new instrument for single cell omics profiling. Funded by a Genome BC Pilot Innovation Fund grant, the project is a close collaboration with the groups of Dr. Marco Marra (Medical Genetics) and Dr. Karen Cheung (Biomedical Engineering) at the University of British Columbia. The candidate will have the opportunity to work with unique and complex single cell imaging, DNA and RNA sequencing datasets, profiling tumour heterogeneity and evolution.

By joining the Steif Lab, you will develop close relationships with world-renown specialists in genomics and bioinformatics and have access to robust high performance computing and next generation sequencing facilities, all while living in one of the most beautiful, diverse and eclectic cities in the world.

We offer a competitive salary, excellent benefits and significant career development opportunities.

Responsibilities

Working in a multidisciplinary team, the postdoctoral fellow will develop and apply computational tools and analytical workflows for single cell omics analysis. This is a one-year term appointment, with potential for renewal. Responsibilities include:

• Regularly review the scientific literature
• Contribute to experimental design and planning
• Data preprocessing and quality control
• Data analysis, visualization, and biological interpretation
• Develop and maintain well-documented code
• Regularly update Dr. Steif and key collaborators on the status of projects
• Participate in and present research updates at lab meetings, team meetings and conferences
• Contribute to scientific writing, including the preparation of research manuscripts and grant applications
• May be involved in recruitment, management, and supervision of trainees

Qualification

• A PhD in bioinformatics, computer science, statistics or related discipline
• At least 2 years of research experience in bioinformatics, with a record of first-author publication
• Experience in genomics and high-throughput sequencing data analysis
• Experience in cancer research is an asset
• Programming fluency in Python or R
• Experience working in a Unix/Linux computing environment
• Critical thinking and attention to detail
• Excellent verbal, written and interpersonal communication skills
• Ability to work independently and in a collaborative interdisciplinary team
• A strong work ethic, with demonstrated ability to manage time and prioritize to meet deadlines

Application

Applicants should submit: a CV; a one-page cover letter explaining how your research experience, interests and career goals align with the position; and the names and contact details of three references to bcgscjobs@bcgsc.ca, using Job Reference No: PDF_01553_Steif Lab_2023_02_23 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options are available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

We are currently looking for a Postdoctoral Fellow to join Dr. Andrew Roth’s and Dr. Adi Steif’s computational cancer genomics research groups at the BC Cancer Research Institute (BCCRI).

The current position is for a candidate with experience developing and applying computational methods to analyze high throughput biological data. The successful applicant will be part of an exceptional multidisciplinary team developing and applying single cell multiomic methods to study evolution and disease transformation risk in follicular lymphoma (FL). Funded by a multi-year Terry Fox New Frontiers Program Project Grant, the project is a close collaboration with clinicians, molecular biologists and bioinformatic scientists. The candidate will have the opportunity to work with a unique and complex dataset which includes single cell DNA, RNA and epigenetic data.

This is an opportunity to work with highly motivated colleagues in a creative and dynamic environment. By joining the Roth and Steif labs at the BCCRI, you will develop close relationships with world-renown specialists in genomics and bioinformatics and have access to robust computational and sequencing technology facilities, all while living in one of the most beautiful, diverse and eclectic cities in the world.

We offer a competitive salary, excellent benefits and significant career development opportunities

What you’ll do

Working in a multidisciplinary team, the postdoctoral fellow will develop and apply scalable analytical workflows for multiomic data integration and biological interpretation. The appointment is for one year in the first instance, with potential for renewal. Responsibilities include:

• Regularly review the scientific literature
• Contribute to experimental design and planning
• Data preprocessing and quality control
• Data analysis, visualization, and biological interpretation
• Develop and maintain well-documented code
• Regularly update Drs. Roth and Steif as well as key collaborators on the status of projects
• Participate in and present research updates at lab meetings, team meetings and conferences
• Contribute to scientific writing, including the preparation of research manuscripts and grant applications
• May be involved in recruitment, management, and supervision of trainees

What you bring

• A PhD in bioinformatics, computer science, statistics or related discipline
• At least 2 years of research experience in bioinformatics, with a record of first-author publication
• Experience in genomics and high-throughput sequencing data analysis
• Experience in cancer research is an asset
• Programming fluency in Python or R
• Experience working in a Unix/Linux computing environment

You have:

• Critical thinking and attention to detail
• Excellent verbal, written and interpersonal communication skills
• Ability to work independently and in a collaborative interdisciplinary team
• A strong work ethic, with demonstrated ability to manage time and prioritize to meet deadlines
• Commitment to upholding the shared responsibility of creating lasting and meaningful reconciliation in Canada as per TRC (2015) and BC's Declaration on the Rights of Indigenous Peoples Act (2019).
• Knowledge of social, economic, political and historical realities impacting indigenous communities and familiarity with Indigenous Cultural Safety and anti-racism and accompanying reports (BC DRIPA, TRC, etc.).

What we bring

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: Temporary, Casual 
Location: 675 West 10th Avenue, Vancouver BC, V5Z 1G1
Hours of Work: Monday to Friday; 0830-1630
 

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

 

How to Apply

Applicants should submit: a CV; a one-page cover letter explaining how your research experience, interests and career goals align with the position; and the names and contact details of 3 references. 

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

 

What we do

About the GSC:

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The Genome Sciences Centre (GSC) is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics and bioinformatics pursuing novel treatment strategies for cancer and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research.

The GSC is part of BC Cancer Research Institute and the Provincial Health Services Authority (PHSA).

BC Cancer provides comprehensive cancer control for the people of British Columbia.

BC Cancer is part of the Provincial Health Services Authority (PHSA).

(PHSA) plans, manages and evaluates specialized health services with the BC health authorities to provide equitable and cost-effective health care for people throughout the province. Our values reflect our commitment to excellence and include: Respect people – Be compassionate – Dare to innovate – Cultivate partnerships – Serve with purpose.

Learn more about PHSA and our programs: jobs.phsa.ca/programs-and-services

PHSA is committed to employment equity, encouraging all qualified individuals to apply. We recognize that our ability to provide the best care for our diverse patient populations relies on a rich diversity of skills, knowledge, background and experience, and value a safe, inclusive and welcoming environment.

Reconciliation is an ongoing process and a shared responsibility for all of us. The BC Governments’ unanimous passage of the Declaration on the Rights of Indigenous Peoples Act was a significant step forward in this journey—one that all health authorities are expected to support as we work in cooperation with Indigenous Peoples to establish a clear and sustainable path to lasting reconciliation. True reconciliation will take time and ongoing commitment to work with Indigenous Peoples as they move toward self-determination. Guiding these efforts Crown agencies must remain focused on creating opportunities that implement the Truth and Reconciliation Commission Mandate.

Job Summary
Researchers in the Department of Molecular Oncology at BC Cancer Research Institute use the latest technologies to rapidly identify genes that are involved in the development of cancer. We are seeking a highly-motivated, organized, driven individual with an interest or past experience with working with research animals in an academic setting. This entry level position will provide the successful candidate with an opportunity to work and learn within an academic research environment where continual training and learning is greatly encouraged. The core focus of this position will be handling and working with research animals, as well as, conducting research experiments on animals; hands-on training will be provided to the successful candidate. This animal tech position will be involved with performing research in drug pharmacology directed at human tumours, with assays in immunodeficient mice (xenotransplants).

Organizational Status
The successful applicant will report to the Principal Investigator or his/her delegate and may assist in overseeing technical work of students and trainees.

Work Performed

• Perform and/or oversee animal procedures involving immunization, oral gavage, injections, tumour inoculation, tumour volume measurements, blood and tissue collection, surgical procedures, necropsy, and post-operative care.
• Assist in the daily care of transgenic animals and maintains colonies of human tumour bearing immunodeficient animals.
• Daily health monitoring and care of laboratory animals.
• Plan and perform animal experiments utilizing complex procedures and/or techniques.
• Be able to recognize and resolve behavioral and/or housing issues; may provide technical instructions and training for other staff and/or trainees
• Process tissue samples and carry out primary cell isolation as instructed.
• Carry out laboratory techniques following standard operating protocols ages, tables, graphs and charts.
• Maintain both laboratory and laboratory records of both animal data and experimental data; when required to summarize results in research reports and lab presentations.
• Perform other related duties as assigned.
• On a rotation basis, must be available for emergency calls 24/7 and respond appropriately.

Minimum Qualifications
Completion of a relevant technical program or a university degree in a relevant discipline and a minimum three years of related experience or an equivalent combination of education and experience.

• Willingness to respect diverse perspectives, including perspectives in conflict with one’s own
• Demonstrates a commitment to enhancing one’s own awareness, knowledge, and skills related to equity, diversity, and inclusion

Preferred Qualifications

• Postgraduate degree in Science is preferred.
• CALAS certification (e.g. RLAT) is an asset.
• Minimum of 3 years related experience or the equivalent combination of education and experience.
• Experience with cell culture and aseptic technique preferred, involving both isolation and maintenance of rodent primary cultures and cell lines.
• Experience in the use and handling of hazardous materials such as biological agents and cytotoxic drugs is essential.
• Experience in the monitoring and management of human tumour bearing animals.
• A working knowledge of the CCAC guidelines and compassion and sensitivity for animals.
• Strong interpersonal skills and the ability to interact positively and productively with other team members are essential.
• Ability to communicate effectively both orally and in writing.
• The successful candidate must be well-organized, conscientious, understand the importance of detail, and be able to multi-task and prioritize duties effectively.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: SS_R00008_Systems_2023_02_07

The Systems Security Specialist is a subject matter expert who participates in the running of a heterogeneous compute facility for a state of the art research facility. This facility encompasses over 300 desktop seats, 12PB of networked storage and over 24000 cores of clustered high performance compute (HPC). This position will report to the Systems Manager.

Key Accountabilities

·     Configuration and tuning of Windows/Linux and Mac operation systems, installation of software onto systems

·     Maintenance of Microsoft Enterprise applications such as Exchange, Active Directory and Windows servers.

·     Responsible for monthly Windows security updates of client machines and servers

·     Advising the Systems Manager and participating in planning solutions for future directions as defined by the GSC

·     Assisting junior and intermediate team members

·     Documenting processes and maintaining knowledge bases

·     Other duties as prescribed by supervisor

Qualifications

A level of education, training, and experience equivalent to a Bachelor’s degree, or equivalent experience. Four (4) years’ experience in a systems administrator role. With a focus on Exchange, Active directory.

High level of expertise with the Windows operating system including tuning and the creation of installation repositories. Deep understanding of Windows internals will be beneficial.

Network administration experience is beneficial, as is understanding the fundamentals of inter-server connectivity.

Demonstrated proficiency in working in a high throughput service desk and being able to manage multiple projects at a time.

Self-motivated, personal accountability with the ability to work independently within a team environment following prescribed processes with the ability to give direction to junior and intermediate team members. Ability to plan, organize and coordinate a variety of activities to ensure maximum effectiveness.

Excellent oral and written communication skills with the ability to communicate effectively and tactfully with individuals at all levels, both internal and external to the GSC. Strong analytical skills. A problem solver able to dive deep into a problem without losing sight of the big picture and working with integrity, adaptability and originality. Physical ability to perform the duties of the job and lift 50 lbs.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: SS_R00008_Systems_2023_02_07 in the subject line of your email.

This posting will remain online until filled.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options are available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No.: RPC2_R00026_2023_02_03

Reporting to Projects Team Leader and working closely with the Principal Investigators and Project Leaders, you will play a key role in managing research projects and grants within the context of a research culture with established policies and procedures, vision and values. The major focus of this position is to work with the Principal Investigators and Project leaders to establish the objectives, milestones, and budgets for various research projects and grants, and develop  strategies to monitor the progress of projects to ensure project objectives and milestones are successfully met.

Duties/Accountabilities

• Establishing budgets for research projects, grants, collaborations and core activities
• Assisting with preparing grants, progress reports, statement of work documents, compliance documents, sample status or analysis reports
• Monitoring budgets and expenditures
• Establishing, monitoring, and coordinating project progress, milestones, deadlines and objectives
• Recommending strategies for improving projects management methods and processesIdentifying, problem solving and working to remove barriers to successful project completion
• Liaising with grant/core funding agencies
• Interacting directly with research collaborators or clinical study teams as required
• Provides work directions to trainees and staff as appropriate.
• Performing other related duties as appropriate

Qualifications

While equivalencies will be considered, ideally you bring a degree in Science (preferably Genetics, Biochemistry, Microbiology or Computer Science) plus a minimum of 5 years' recent related experience in project management and/or research development management.

Certification as a Project Management professional will help you make the short list, as will recent experience in academic scientific research, clinical trials research, biotech or software industry. Proficiency with MS Word, Excel and Project is essential and you should have excellent organizational, analytical and verbal and written communication skills.

Successful candidate(s) will be offered positions through Provincial Health Services Authority at the Research Project Coordinator II level, which is equivalent to that described above.

Core Skills and Abilities

Excellent written and verbal communication skills and proactive interactions with collaborators are a must to perform successfully in this position. Active participation in laboratory meetings and seminars relevant to the project activities is highly encouraged. Demonstrated ability to manage multiple resource intense projects within a fast paced environment.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using  Job Reference No.: RPC2_R00026_2023_02_03 in the subject line of your email.

This posting will remain online until filled.

Please note All jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options are available for this position upon request and is subject to change in accordance with GSC’s Operational needs and PHSA’s Flexible Work Options Policy.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens, permanent residents, applicants with a valid status to work in Canada will be given priority.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No. CB_Ryan Morin Lab_HSA 140385_P01060_2023_02_03

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA. As such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Computational Biologist performs bioinformatics analyses and contributes to software development related to the operation of a large-scale clinical sequencing facility.

Duties

1. Contributes to the design, development, implementation, validation, running, and maintenance of clinical bioinformatics pipelines and related databases.
2. Contributes to incorporation of third-party software into clinical bioinformatics pipelines, including:
   1. identifying candidate software to consider
   2. comparing software candidates to aid in selection
   3. determining optimal parameters for the chosen software
   4. developing interfaces to integrate the chosen software and
   5. validating integration of the chosen software
3. Participates in the development of novel software solutions, as directed by the Assistant Bioinformatics Coordinator or Clinical Bioinformatics Coordinator.
4. Participates in peer code review.
5. Contributes to writing and updating official procedures and other documentation related to clinical bioinformatics pipelines.
6. Verifies results produced by clinical bioinformatics pipelines.
7. Performs exploratory analyses to identify potential root causes of issues encountered during production processing, and implements corrective actions as directed by the Assistant Bioinformatics Coordinator or Clinical Bioinformatics Coordinator.
8. Performs bioinformatics analyses to answer questions from the Clinical Director, Clinical Bioinformatics Coordinator, or Assistant Bioinformatics Coordinator.
9. Presents implementation plans, analysis results, and validation results internally and externally, in oral presentations and written documentation.
10. Contributes to the development of research papers by providing materials, methods, and/or analyzed data.
11. Participates in the training of others through orientation, informal instruction, and sharing of job information.
12. Performs other related duties as required.

Qualifications

Education, Training and Experience

• Graduation from a recognized Bachelor of Applied Science or Bachelor of Science Program in either Biological Sciences or Computer Science.
• Two (2) year’s of recent related experience or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

• Demonstrated skill with Python or other similar high level languages
• Functional knowledge of distributed version control systems, such as Git.
• Demonstrated ability in R or other similar statistical programming languages
• Familiarity with relational databases, such as PostgreSQL, and with ORMs
• Ability to program and run analyses in a production environment
• Excellent verbal and written communication skills
• Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment
• Demonstrated ability to efficiently organize work assignments to complete required tasks on time
• Familiarity with next-generation sequencing, cancer genetics, principles of clinical testing, experimental design, statistical hypothesis testing, and/or machine learning would be considered an asset
• Ability to use related equipment

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: CB_Ryan Morin Lab_HSA 140385_P01060_2023_02_03 in the subject line of your email.

This posting will remain online until filled.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options are available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

ATTN: PHSA Employees:

To be considered as a PHSA employee (internal applicant) for this position, you must apply online via your internal profile at http://internaljobs.phsa.ca   

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: RP_R00008_Systems_2022_12_16

Enterprise Administrator - Systems

The Enterprise Administrator is a subject matter expert who participates in the running of a heterogeneous compute facility for a state of the art research facility. This facility encompasses over 300 desktop seats, 20PB of networked storage and over 30,000 cores of clustered high performance compute (HPC). This position will report to the Systems Manager. The GSC Systems team is looking for a team member to support the current server and storage administrators with meeting our objectives.

The ideal candidate will have experience administering Linux/Windows servers and working with NFS and SMB. This role will also have a focus on enterprise storage so experience with storage clusters from vendors such as HP,IBM,Netapp,Dell etc is highly beneficial. A keenness to learn new things and grow within our team is desirable.

Key Accountabilities

· Configuration and tuning of Windows or Linux operation systems, installation of software onto systems

· Provisioning NFS and SMB shares and troubleshooting storage issues on Windows, Mac and Linux

· Maintenance of Enterprise networked storage

· Assisting the storage team in managing the hardware/software and administering the storage clusters

· Assisting the storage team with data backup and retrieval tasks

· Participate in the archiving of data to LTO tape libraries

· Assisting junior team members

· Documenting processes and maintaining knowledge bases

· Other duties as prescribed by supervisor

Qualifications

A level of education, training, and experience equivalent to a Bachelor’s degree, or equivalent experience. Two (2) years experience in Linux or Windows systems, or storage cluster administration role.

Intermediate level of expertise with the Linux operating system with preference to Centos/RedHat variants including building and configuring both physical and virtual servers . Understanding of Linux internals and CLI will be beneficial.

Experience with enterprise class storage systems, and an understanding of the fundamentals of their setup and design is an advantage.

Proficiency in scripting languages such as bash, perl and python.

Self-motivated, personal accountability with the ability to work independently within a team environment following prescribed processes with the ability to give direction to junior and intermediate team members. Ability to plan, organize and coordinate a variety of activities to ensure maximum effectiveness.

Excellent oral and written communication skills with the ability to communicate effectively and tactfully with individuals at all levels, both internal and external to the GSC. Strong analytical skills. A problem solver able to dive deep into a problem without losing sight of the big picture and working with integrity, adaptability and originality. Physical ability to perform the duties of the job and lift 50 lbs.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: RP_R00008_Systems_2022_12_16 in the subject line of your email.

This posting will remain online until filled.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options are available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Do you have a background in science research — from its processes and practices to proposals & peer-review? Can you develop an award winning grant application, facilitate efficient and productive meetings, gather the right information and engage the right people at the right ti​me? We're looking for a Research Project Manager to help GSC faculty and leaders continue to deliver world-leading genomics, bioinformatics, cancer and precision medicine research.

Job Reference No.: RPC2_R00026_2023_01_20

Summary

Reporting to Projects Team Leader and working closely with the Principal Investigators and Project Leaders, you will play a key role in managing research projects and grants within the context of a research culture with established policies and procedures, vision and values. The major focus of this position is to work with the Principal Investigators and Project leaders to establish the objectives, milestones, and budgets for various research projects and grants, and develop  strategies to monitor the progress of projects to ensure project objectives and milestones are successfully met.

Duties/Accountabilities

• Establishing budgets for research projects, grants, collaborations and core activities
• Assisting with preparing grants, progress reports, statement of work documents, compliance documents, sample status or analysis reports
• Monitoring budgets and expenditures
• Establishing, monitoring, and coordinating project progress, milestones, deadlines and objectives
• Recommending strategies for improving projects management methods and processesIdentifying, problem solving and working to remove barriers to successful project completion
• Liaising with grant/core funding agencies
• Interacting directly with research collaborators or clinical study teams as required
• Provides work directions to trainees and staff as appropriate.
• Performing other related duties as appropriate

Qualifications

While equivalencies will be considered, ideally you bring a degree in Science (preferably Genetics, Biochemistry, Microbiology or Computer Science) plus a minimum of 5 years' recent related experience in project management and/or research development management.

Certification as a Project Management professional will help you make the short list, as will recent experience in academic scientific research, clinical trials research, biotech or software industry. Proficiency with MS Word, Excel and Project is essential and you should have excellent organizational, analytical and verbal and written communication skills.

Successful candidate(s) will be offered positions through Provincial Health Services Authority at the Research Project Coordinator II level, which is equivalent to that described above.

Core Skills and Abilities

Excellent written and verbal communication skills and proactive interactions with collaborators are a must to perform successfully in this position. Active participation in laboratory meetings and seminars relevant to the project activities is highly encouraged. Demonstrated ability to manage multiple resource intense projects within a fast paced environment.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using  Job Reference No.: RPC2_R00026_2023_01_20 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely on a temporary basis. This restriction would be re-evaluated upon re-contracting.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens ,permanent residents, applicants with a valid status to work in Canada will be given priority.

Please note All jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options are available for this position upon request and is subject to change in accordance with GSC’s Operational needs and PHSA’s Flexible Work Options Policy.

Why work at the GSC

As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC. But it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers and clinicians. We look for people who share our core values—science, timeliness and respect—to join us in our mission to provide genomics, bioinformatics and proteomics technology and expertise for the benefit of human health and society.

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Job Reference No: GST_P00634_HSA 136835_2022_11_24

Role Summary

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.The Genome Sciences Technologist performs various molecular biology techniques and procedures including library construction which are involved in the operation of a large scale, high throughput DNA mapping and DNA sequencing production facility.

This is a temporary full-time renewable position.

Qualifications

Education, training and experience:

Graduation from a recognized diploma program in Biotechnology, Microbiology or Biochemistry and two (2) years’ of recent related experience in a research laboratory or an equivalent combination of education, training and experience acceptable to the Genome Sciences Centre Group Leaders and Production Coordinators.

Skills and abilities:

• Knowledge of molecular biology techniques particularly DNA and RNA preparation and manipulation
• Demonstrated ability to perform detailed procedures reproducibly and accurately
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment
• Demonstrated ability to efficiently organize work assignments and establish priorities
• Basic knowledge of and ability to operate personal computers

To Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No.: GST_P00634_HSA 136835_2022_11_24 in the subject line of your email.

This posting will remain online until filled.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Apply Here

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.: GET_P00651_HSA 136840_2022_11_24

Job Summary:

Reporting to the group leader and in accordance with established policies, standards and procedures, this position performs technical work related to the repair, maintenance, calibration, inspection and evaluation of genomics laboratory equipment.

This is a temporary full-time renewable union position.

Duties:

1. Repairs and maintains laboratory equipment related to high throughput genomics such as robotic liquid handlers (Hamilton Nimbus and Starlet, Janus), centrifuges, thermocyclers, sequencers, Barcode printers,  Agilent bioanalysers, Speed  vac, autoclave etc..
2. Performs inspections, tests, troubleshooting, calibration and repair of equipment as necessary by methods such as identifying faults, disassembling, replacing parts, making adjustments or calibrations, reassembling and testing equipment to determine if functioning properly.Contacts and co-ordinates vendors and service representatives as necessary.
3. Performs preventative maintenance on equipment by methods such as visually inspecting equipment for signs of wear and/or malfunctions, cleaning, lubricating and replacing parts. Maintains records and revises standard operating procedures as required.
4. Provides consultations and training to staff and demonstrates procedures to operators of equipment on use for optimal performance and safety.
5. Communicates status and scheduling repairs and equipment moves with inter-team and department.
6. Modifies, redesigns and/or fabricates equipment for specialized applications by reviewing specifications with appropriate personnel, writing specifications for new equipment/devices and/or changing system operating parameters.
7. Participates in the identification of equipment needs, evaluates equipment based on these needs and makes recommendations on the purchase of various products to Leader(s).
8. Programs new protocols on equipment including Hamilton liquid handler and tetrads as required..
9. Documents repair and equipment related activities including report generation.
10. Performs other duties as required.

Qualifications

Education, Training and Experience

Graduate of a recognized program in Biomedical Engineering Technology plus two (2) years recent related experience or an equivalent combination of education, training and experience.  

Skills and Abilities

• Knowledge of similar laboratory equipment especially robot liquid handlers.
• Demonstrated ability to communicate effectively both verbally and in writing with all levels of staff.
• Able to adapt to changes in work and demonstrate initiative to prioritize, track and coordinate tasks around production needs.
• Demonstrated administrative, organizational and record keeping skills.
• Ability to work independently with minimal direction and supervision.
• Experience with computer software applications such as Microsoft Excel, Microsoft Access and JIRA.
• Physical ability to perform the duties of the job.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: GET_P00651_HSA 136840_2022_11_24 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely on a temporary basis. This restriction would be re-evaluated upon re-contracting.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Job Summary:

The candidate would work within a dynamic and vibrant lab with a proven track record of outstanding achievements and contributions in breast oncology research. This position allows the candidate to contribute bold and innovative research that can be translated to new understanding in the evolutionary processes that drive cancers.

This position's primary focus in the lab will be to lead and to participate in projects based on candidate's desire concentrated on investigating genetics of breast oncology, cancer evolutionary, and development of novel therapeutics. Using the wide network of connections and collaborations of the principal investigator, and extensive biomedical resources at the institution, candidates will be able to build on the existing research of the lab to quickly start up their own research projects.

The position will provide a unique opportunity for mentoring trainees, supervising analysts and interacting with industry. This is an excellent platform to receive outstanding training to gain the important skills for a successful medical research career in academia or industry.

This funded position with the University of British Columbia, at the BC Cancer Research Centre allows the candidate to flourish under the guidance of an experienced mentor.

Organizational Status:

The Postdoctoral Fellow will play a leadership role in the Aparicio lab, and will be reporting directly to Dr. Samuel Aparicio who is the primary investigator of the laboratory. More information on the lab, please visit https://aparicio.molonc.ca

The Department of Pathology and Laboratory Medicine at UBC is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients.  The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence.

Work Performed:

• Management and supervision of trainees;
• May be involved in recruitment and training of trainees;
• Performing regular reviews of the relevant literature;
• Planning and designing of experiments;
• Analyzing, interpreting and compiling data in study reports, presenting results, and participating in the preparation of scientific manuscripts and grant application packages;
• Updating Dr. Aparicio and the group on the status of projects during lab meetings, in email correspondence and phone conferences;
• Managing projects with key academic and industry partners.

Minimum Qualifications:

• PhD degree in the computer science, bioinformatics or equivalent
• At least 4 years experience in bioinformatics research
• Experience in genomics and next-generation sequencing
• Extensive knowledge of cellular and molecular biology, biochemistry and genetics
• Experience with cancer research a plus
• Proven ability to multi-task in a deadline oriented environment with minimal supervision
• Effective oral and written communication, analytical, and interpersonal skills
• Excellent organizational skill and ability to learn new skills quickly
• Ability to work independently and within a team environment.
• Accuracy and attention to detail required
• Candidates should demonstrate the ability to work in a highly interdisciplinary environment.

Supervision Received:

• Works independently under direction of PI, Dr. Samuel Aparicio
• Opportunities to work collaboratively with Industry partners and other researchers at UBC and globally

Supervision Given:

• Assists and oversees research assistants and students as required
• Assists and provides guidelines to other research members, as required

How to Apply:

Exceptional candidates should submit a cover letter outlining your research interests and fit with the laboratory's research, curriculum vitae, and the names of three referees willing to provide letters of reference.

Due to the number of resumes we receive, we are unable to confirm receipt of submissions over the phone, or provide the status of the competition. Only shortlisted candidates will be contacted.

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

Equity and diversity are essential to academic excellence.  An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged.  We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.

All qualified candidates are encouraged to apply; however Canadians and permanent residents will be given priority.

Email to apply: careersmolonc@bccrc.ca

Please put Bioinformatics PDF in the subject line.

JOB SUMMARY

Researchers in the Department of Molecular Oncology at the BC Cancer Research Centre use the latest technologies to rapidly identify genes that are involved in the development of cancer. You will become an integral part of the animal research team, providing technical support on animal research for multiple core projects within the lab.

DUTIES/ACCOUNTABILITIES

• Perform a variety of established technical procedures according to written protocols.
• Perform experiments by following established laboratory procedures according to written protocols.
• Record results, including computer data entry.
• Provide input regarding modification of procedures as requested by the Department Head, Principal Investigator, or designate.
• Maintain and store cell lines and primary cultures.
• Maintain and store test materials and products.
• Maintain inventory of laboratory supplies and equipment.
• May demonstrate work methods or procedures to less experienced assistants as designated.

QUALIFICATIONS

• A level of education, training, and experience equivalent to graduation from a recognized Bachelor’s program in an appropriate discipline (e.g. Bachelor of Science)
• Two (2) years of recent related experience in a research laboratory
• As this role will be spending the majority of the time in an animal research facility working with mice – mice handling experience is preferred.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: CB_HSA# 134262_P01060_CCG_2022_10_11

Summary

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA. As such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Computational Biologist performs bioinformatics analyses and contributes to software development related to the operation of a large-scale clinical sequencing facility. This is a temporary renewable full-time position

Duties

Contributes to the design, development, implementation, validation, running, and maintenance of clinical bioinformatics pipelines and related databases.

• Contributes to incorporation of third-party software into clinical bioinformatics pipelines, including:
  1. identifying candidate software to consider
  2. comparing software candidates to aid in selection
  3. determining optimal parameters for the chosen software
  4. developing interfaces to integrate the chosen software and
  5. validating integration of the chosen software
• Participates in the development of novel software solutions, as directed by the Assistant Bioinformatics Coordinator or Clinical Bioinformatics Coordinator.
• Participates in peer code review.
• Contributes to writing and updating official procedures and other documentation related to clinical bioinformatics pipelines.
• Verifies results produced by clinical bioinformatics pipelines.
• Performs exploratory analyses to identify potential root causes of issues encountered during production processing, and implements corrective actions as directed by the Assistant Bioinformatics Coordinator or Clinical Bioinformatics Coordinator.
• Performs bioinformatics analyses to answer questions from the Clinical Director, Clinical Bioinformatics Coordinator, or Assistant Bioinformatics Coordinator.
• Presents implementation plans, analysis results, and validation results internally and externally, in oral presentations and written documentation.
• Contributes to the development of research papers by providing materials, methods, and/or analyzed data.
• Participates in the training of others through orientation, informal instruction, and sharing of job information.
• Performs other related duties as required.

Qualifications

Education, Training and Experience

• Graduation from a recognized Bachelor of Applied Science or Bachelor of Science Program in either Biological Sciences or Computer Science.
• Two (2) year’s of recent related experience or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

• Demonstrated skill with Python or other similar high level languages
• Functional knowledge of distributed version control systems, such as Git.
• Demonstrated ability in R or other similar statistical programming languages
• Familiarity with relational databases, such as PostgreSQL, and with ORMs
• Ability to program and run analyses in a production environment
• Excellent verbal and written communication skills
• Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment
• Demonstrated ability to efficiently organize work assignments to complete required tasks on time
• Familiarity with next-generation sequencing, cancer genetics, principles of clinical testing, experimental design, statistical hypothesis testing, and/or machine learning would be considered an asset
• Ability to use related equipment

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using  Job Reference: CB_HSA # 134262_P01060_CCG_2022_10_11 in the subject line of your email.

As this is a union position, you will also have to apply either as an internal or external applicant through http://www.phsa.ca/careers using the posting reference 134262.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working on a hybrid basis both remotely and onsite on a temporary basis. This restriction would be re-evaluated upon re-contracting.

Under the Provincial Health Officer (PHO) order on mandatory vaccination for health-care workers, any new employees hired by a B.C. health authority must be fully vaccinated for COVID-19.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

One postdoctoral fellow position is immediately available at the BC Cancer Research Institute in Vancouver, Canada for the development of novel radiopharmaceuticals for cancer imaging and radiotherapy. The postdoctoral fellow will conduct research in the design and synthesis of radioligands targeting biomarkers overexpressed in cancers. Research activities will involve the production and isolation of radioisotopes, peptide and multi-step organic synthesis, and radiolabeling small molecules, peptides and antibodies with various imaging and radiotherapeutic isotopes (F-18, Ga-68, Zr-89, Tc-99m, I-123, In-111, Lu-177, Ac-225 …).

Qualified candidates should have a PhD degree in radiochemistry, organic or medicinal chemistry with experience in peptide or multi-step organic synthesis. Experience with HPLC, micro-scale reactions, and radiochemistry is strongly desirable but not required. The ability to perform research in a collaborative environment is required including excellent oral and written communication skills. This joint position between BC Cancer Research Institute and University of British Columbia (UBC) is for a period of two years with the possibility of renewal.

Interested candidates should send a letter of application, curriculum vitae, and names of three references to :
Dr. Kuo-Shyan Lin
Senior Scientist, BC Cancer Research Centre
Associate Professor, University of British Columbia
E-mail: klin@bccrc.ca

Review of applications will begin immediately and will continue until the position is filled.

JOB SUMMARY

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position. These positions supervise designated staff by scheduling and assigning work, and assist in daily animal care operations by leading various health monitoring and colony management programs, trouble-shooting minor issues and performing other administrative tasks. These positions also maintain the daily care of laboratory mice and perform various surgical procedures and laboratory techniques.

                                               

DUTIES/ACCOUNTABILITIES

• Develops, implements, reviews and updates animal care standard operating procedures for assigned area.

• Leads various animal care programs such as health monitoring and colony management.

• Maintains current knowledge of, and ensures compliance with, animal care regulations.

• Supervises designated staff by scheduling and assigning work, providing orientation and training and monitoring performance.

• Maintains daily care of laboratory mice including maintaining adequate food and water levels and observing mice for general health conditions.

• Performs surgeries and techniques including blood collection, surgical implantations, tumour implantation, injection of solutions, collection of tissues and organs and embryo manipulations, and cryopreservation.

• Performs laboratory techniques such as media preparation, cell culture and hormone preparation, and polymerase chain reaction analysis as required.

• Leads training programs, prepares and gives presentations and orients and trains staff and animal users on proper animal care theory, protocols, techniques and procedures.

• Changes and cleans animal cages, bottles and racks.

• Performs general cleaning of animal facilities including disinfecting equipment, walls, floors, rooms, etc.

• Performs census duties such as counting cages and reporting cage numbers.

• Receives and processes laboratory animal care supplies.

                                               

QUALIFICATIONS

A level of education, training, and experience equivalent to graduation from a recognized program in Animal Health or Veterinary Technology, or a Bachelor’s program in an appropriate discipline (e.g. Animal Science); plus five (5) years of recent related experience in a research laboratory, including two (2) years in a supervisory capacity.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: RPC_R00022_Projects_2022_11_15

Summary

Reporting to Projects Team Leader and working closely with the Principal Investigators and Project Leaders, you will play a key role in managing research projects and grants within the context of a research culture with established policies and procedures, vision and values. The major focus of this position is to work with the Principal Investigators and Project leaders to establish the objectives, milestones, and budgets for various research projects and grants, and monitor and facilitate progress against these objectives and milestones.

Duties/Accountabilities

• Establishing budgets for research projects, grants, collaborations and core activities
• Assisting with preparing grants, progress reports, statement of work documents, compliance documents, sample status or analysis reports
• Monitoring budgets and expenditures
• Establishing, monitoring, and coordinating project progress, milestones, deadlines and objectives
• Recommending strategies for improving projects management methods and processes
• Liaising with grant/core funding agencies
• Interacting directly with research collaborators or clinical study teams as required
• Performing other related duties as appropriate

Qualifications

While equivalencies will be considered, ideally you bring a degree in Science (preferably Genetics, Biochemistry, Microbiology or Computer Science) plus 5 years' recent related experience in project management and/or research development management.

Certification as a Project Management professional will help you make the short list, as will experience in academic scientific research, clinical trials research, biotech or software industry. Proficiency with MS Word, Excel and Project is essential and you should have excellent organizational, analytical and verbal and written communication skills.

Successful candidate(s) will be offered positions through Provincial Health Services Authority at the Research Project Coordinator level, which is equivalent to that described above.

Core Skills and Abilities

Excellent written and verbal communication skills and proactive interactions with collaborators are a must to perform successfully in this position. Active participation in laboratory meetings and seminars relevant to the project activities is highly encouraged.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: RPC_R00022_Projects_2022_11_15 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working on a hybrid basis, both remotely within BC and onsite in the GSC office in Vancouver on a temporary basis. This restriction would be re-evaluated upon re-contracting.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.