Careers

Job Reference Number: PDF_01553_Steif Lab_2022_05_16

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. We are currently looking for a Postdoctoral Fellow to join Dr. Adi Steif’s computational biology group.

The successful incumbent will lead the analysis of single cell data from a novel instrument, under development in collaboration with the groups of Dr. Karen Cheung (Biomedical Engineering) and Dr. Marco Marra (GSC / Medical Genetics). Funded by Genome BC, the project aims to improve the scalability and accuracy of cell isolation, in order to investigate tumour cellular diversity and evolution.

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on improving genome sequencing technology, interpretation and application. By working within the Steif Lab at the GSC, you will develop close relationships with world-renown specialists in bioinformatics and have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

Apply now!

Responsibilities

Working in a multidisciplinary team, the postdoctoral fellow will contribute to experimental design and protocol optimization. They will develop scalable analytical workflows in a high-performance computing environment to characterize the genomes and transcriptomes of cancer cells. This is a one-year term appointment, with potential for renewal.

• Regular review of the scientific literature
• Contribute to experimental design and planning
• Data preprocessing and quality control
• Data analysis, visualization, and biological interpretation
• Develop and maintain well-documented code
• Regularly update Dr. Steif and key collaborators on the status of projects
• Participate in and present research updates at lab meetings and team meetings
• Contribute to scientific writing, including the preparation of research manuscripts and grant applications
• May be involved in recruitment, management, and supervision of trainees

Qualifications

• A PhD in bioinformatics, biostatistics, computer science or related discipline
• At least 3 years of research experience in computational biology, with a record of first-author publication
• Experience in genomics and the analysis of sequencing data
• Knowledge of molecular biology and genetics
• Experience in cancer research is an asset
• Programming fluency in Python or R
• Experience working in a Unix/Linux environment
• Critical thinking and attention to detail
• Excellent verbal, written and interpersonal communication skills
• Ability to work independently and in a collaborative interdisciplinary team
• A strong work ethic, with demonstrated ability to manage time and prioritize to meet deadlines

How to Apply

Applicants should submit: a CV; a one-page cover letter highlighting relevant research experience, interests and goals; and the names and contact details of 3 references. 

Please send your application to bcgscjobs@bcgsc.ca and include the job reference number in the subject line of the email. While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

We believe that equity and diversity are essential for the advancement of human knowledge and science.   We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

The GSC is part of BC Cancer Research Institute and the Provincial Health Services Authority (PHSA). Please note that as per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

One postdoctoral fellow position is immediately available at the BC Cancer Research Institute in Vancouver, Canada for the development of novel radiopharmaceuticals for cancer imaging and radiotherapy. The postdoctoral fellow will conduct research in the design and synthesis of radioligands targeting biomarkers overexpressed in cancers. Research activities will involve the production and isolation of radioisotopes, peptide and multi-step organic synthesis, and radiolabeling small molecules, peptides and antibodies with various imaging and radiotherapeutic isotopes (F-18, Ga-68, Zr-89, Tc-99m, I-123, In-111, Lu-177, Ac-225 …).

Qualified candidates should have a PhD degree in organic or medicinal chemistry with experience in peptide or multi-step organic synthesis. Experience with HPLC, micro-scale reactions, and radiochemistry is strongly desirable but not required. The ability to perform research and development in a collaborative environment is required including excellent oral and written communication skills. This joint position between BC Cancer and University of British Columbia (UBC) is for a period of two years with the possibility of renewal.

Interested candidates should send a letter of application, curriculum vitae, and names of three references to: Kuo-Shyan Lin (klin@bccrc.ca). Review of applications will begin immediately and will continue until the position is filled.

The Department of Radiology at The University of British Columbia (UBC) along with its partners, the BC Cancer Research Institute (BC Cancer) and TRIUMF invite applications for a full-time faculty position in the field of radiotracer and probe development for molecular imaging and therapy of cancers, at the rank of Assistant Professor (tenure track). This position will be based at the BC Cancer Research Institute.

The anticipated start date is July 1, 2022 or upon a date to be mutually agreed. Applications will be accepted until the position is filled.

Job Summary:

Dr. Philipp Lange, Canada Research Chair in Translational Proteomics of Pediatric Malignancies and his team at The University of British Columbia (UBC) in Vancouver, Canada, seek an outstanding candidate with exceptional passion to advance precision oncology for children and the fundamental understanding of proteome modulation in childhood disorders.

Organizational Status:

The successful candidate will report directly to Dr. Philipp Lange, the principal investigator, and will work in a strongly collaborative and collegial fashion with cross-functional project team members to meet research goals and objectives.

Work Performed:

The research associate will lead data analysis and reporting for multiple single case and cohort studies in the precision oncology BRAvE and PROFYLE initiatives as well as collaboration projects. In this role, they will perform statistically robust analysis and integration of molecular (proteomics, genomic, metabolomic) and phenotypic (clinical, immunophenotype, drug perturbation, …) data, write reports and engage with team members and collaborators to provide key input on experimental design, data interpretation and overall direction of the studies. The research associate will also have the opportunity to conduct experiments of their own to advance the studies.

The incumbent will represent the laboratory in national and international initiatives, lead collaborative projects, train graduate and undergraduate students, introduce new methodologies to the lab and make major contributions to grant proposals and manuscripts.

Consequence of Error:

The successful applicant is expected to exercise a considerable amount of judgment, responsibility, and initiative in determining work procedures and methods. He/she should carefully observe and evaluate their work. All works are subject to assessment by Dr. Lange. Consistent poor judgment decisions or errors can result in incorrect data interpretation and potential loss of funding.

Supervision Received:

The applicant is expected to work independently under the direction of Dr. Lange, who will be available to provide consultation on unusual problems and project developments.

Supervision Given:

Assist with training graduate students and junior lab staff; provide input on staff/co-op student selection and performance evaluation.

Qualifications:

• PhD and Postdoctoral in cancer biology, immunology or related area
• Strong publication record
• Fluent in written and spoken English and demonstrated excellence in scientific writing
• Demonstrated exceptional analytical, communication and visualization skills
• Strong statistical foundation and expertise in R or python for data analysis
• Exceptional understanding of biological mechanisms and well read
• Expertise in CRISPER genome editing, mass spectrometry, cell surface and secretome characterization are assets but not required

Research Team & Environment: Located at the BC Children’s Hospital Research Institute (BCCHRI), the leading pediatric research center in Western Canada, you will be embedded in the highly innovative and interdisciplinary research environment spanning BC Children’s Hospital, UBC and BC Cancer Agency. Vancouver repeatedly ranks among the most livable places in the world and combines excellence in research with high quality of life. Excellent opportunities for personal and professional development are provided.

The incumbent will be part of a dynamic team of experimental and computational scientists and embedded in the local BRAvE and national PROFYLE pediatric precision oncology initiatives, where they will work with basic scientists, pathologists, analysts and clinicians. They will work in the newly renovated digital-health offices with direct access to state-of-the-art compute infrastructure and software, as well as, cell and molecular biology facilities, mouse and chicken chorioallantoic membrane (CAM) modeling platforms, mass-spectrometry, next-generation sequencing, flow cytometry, imaging and compute infrastructure.

The Department of Pathology and Laboratory Medicine at UBC is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients.  The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence. 

How to apply:

Review of applications will begin May 1, 2022. The position will commence as soon as possible.

Please send a cover letter expressing your long-term research vision, career goals and fit for the position (detailing how you meet the requirements). PDF copies of your most impactful papers (max 3, submitted manuscripts OK) as well as your CV and contacts (full address, email and phone number) for three references to brenda.tse@ubc.ca. Please send your documents in one PDF file. Only shortlisted candidates will be contacted.

Salary will be commensurate with experience and full benefits will be provided. The term of the position may be extended pending successful review of performance and productivity and continued funding availability.

Job Summary:

Drs. Poul Sorensen, Johal Chair in Childhood Cancer Research, Philipp Lange, Canada Research Chair in Translational Proteomics of Pediatric Malignancies and Gregg Morin seek an outstanding candidate to advance molecular diagnostics in childhood cancer as part of PROFYLE, Canada’s national pediatric precision oncology initiative.

Organizational Status:

The successful candidate will report directly to Dr. Philipp Lange, the principal investigator, and will work in a strongly collaborative and collegial fashion with cross-functional project team members to meet research goals and objectives.

Work Performed:

The postdoctoral fellow will lead a project on the development of mass spectrometry based diagnostic assays for cell surface immunotherapy targets in childhood cancer. Under mentorship of Drs Philipp Lange, Poul Sorensen and Gregg Morin they will refine automated (cell surface) proteome extraction from clinical biopsies and develop PRM and MRM based mass spectrometry approaches for pre-clinical application and clinical translation. They will also have the opportunity to supervise graduate and undergraduate students, gain leadership experience in collaborative projects and contribute to grant applications.

Consequence of Error:

The successful applicant is expected to exercise a considerable amount of judgment, responsibility, and initiative in determining work procedures and methods. He/she should carefully observe and evaluate their work. All works are subject to assessment by Dr. Lange. Consistent poor judgment decisions or errors can result in incorrect data interpretation and potential loss of funding.

Supervision Received:

The applicant is expected to work independently under the direction of Drs. Lange, Sorensen and Morin who will be available to provide consultation on unusual problems and project developments.

Supervision Given:

Assist with training graduate students and junior lab staff; provide input on staff/co-op student selection and performance evaluation.

Qualifications:

• PhD in biochemistry, cancer biology, analytical chemistry or related area
• Strong publication record
• Fluent in written and spoken English and demonstrated excellence in scientific writing
• Demonstrated exceptional communication and analytical skills.
• Demonstrated hands-on expertise in protein mass spectrometry
• Strong statistical foundation and demonstrated expertise in R or python for data analysis
• Hands-on expertise in characterization cell surface proteomes, development of PRM or MRM type assays, and clinical mass spectrometry are important assets

Research Team & Environment: The incumbent will be part of a dynamic team of experimental and computational scientists and embedded in the national PROFYLE pediatric precision oncology initiative where you will work with basic scientists, pathologists, analysts and clinicians to advance precision diagnostics and treatment for children with cancer. You will be located at the BC Children’s Hospital Research Institute and BC Cancer and will have direct access to latest generation mass-spectrometry, state-of-the-art cell and molecular biology facilities, mouse and chicken chorioallantoic membrane (CAM) modeling platforms, next-generation sequencing, flow cytometry, imaging and compute infrastructure. Vancouver repeatedly ranks among the most livable places in the world and combines excellence in research with high quality of life. Excellent opportunities for personal and professional development will be provided.

The Department of Pathology and Laboratory Medicine at UBC is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients.  The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence. 

How to apply:

Review of applications will begin May 1st. The position will remain open until filled and commence as soon as possible. Please send the following as one PDF file to brenda.tse@ubc.ca: a cover letter expressing your long-term research vision, career goals and fit for the position (detailing how you meet the requirements); CV; contacts (full address, email and phone number) for three references; copies of your most impactful papers (max 3, submitted OK).  Only shortlisted candidates will be contacted.

JOB SUMMARY

A position is open immediately for a research engineer specializing in microscopy hardware to work with our interdisciplinary team of researchers and software developers at the British Columbia Cancer Agency (BCCA). We are seeking a passionate individual to join a team of biologists, engineers and data scientists currently developing state of the art methods for spatial imaging of RNA species in human cancers at single cell resolution. Studying tumours at the single cell level can reveal biological differences that may not be resolved when studying the tumour as a whole. The imaging methods being developed include the use of molecularly encoded super-resolution microscopy to detect single molecules of RNA in tissue specimens. The successful candidate will develop and support integrating super-resolution microscopy, fluidics and camera functions to facilitate sequential imaging of human cancers. The candidate will also work with biologists and data scientists to analyze images and identify RNA species. 

You will be on-site in the Department of Molecular Oncology at BC Cancer, working closely with software developers, students and researchers operating at the leading edge of the field of cancer genomics.  As one of the members of the CRUK Grand Challenge IMAXT, our lab has embarked on an ambitious journey of creating the world’s first virtual reality map of cancer, with this role playing a key part in the success of this project.  More information on the lab, please visit https://aparicio.molonc.ca

ORGANIZATIONAL STATUS

We are a small team of software developers and engineers  embedded within a larger cancer research lab.  You will be working closely with the researchers on multiple projects involving microscopy hardware and data generation, reporting to the project lead or designate.  You will also be involved in collaborations within BC Cancer, UBC, SFU and internationally.

WORK PERFORMED

• Development and maintenance of microscopy, fluidics and robotics hardware systems through quantitative feedback and functional requirements definition
• Development and maintenance of hardware instrumentation control software in Python, MATLAB, and C (Arduino)
• Further improvement of the existing experiment protocol and the associated instrumentation
• Assisting in generation and presentation of research results from microscopy system, such as the preparation and running of the instrumentation
• Communication with external vendors regarding the microscope and associated devices
• Participation in meetings with the larger research group
• Assisting in performing computational analysis of digital image files from the system
• Documentation and training of microscope system to other users
• Training of undergraduate students regarding the development of the microscopy system

CONSEQUENCE OF ERROR

Accountable for the correct operation of the microscopy system, failure of which will have significant research progress implications.

SUPERVISION RECEIVED

Supervision from Principal Investigator or designate. Results reviewed for achievement of overall objectives.

SUPERVISION GIVEN

May help to supervise undergraduate trainees.

QUALIFICATIONS

Essential

• Undergraduate degree in Engineering of Applied Science.  Minimum three years of related experience or the equivalent combination of education and experience
• Relevant experience in microscopy, electrical engineering, optics, fluidics and mechatronics
• Programming in Python, MATLAB, and C (Arduino).
• Strong verbal/written communication skills
• Interdisciplinary teamwork experience
• Experience working in an academic research environment

Preferred

• Graduate degree in Engineering or Applied Science
• Experience with root cause analysis
• Experience in software engineering and instrumentation design
• Experience using CAD and rapid prototyping tools
• Experience with basic circuit design and microcontrollers
• Experience working with fluidics devices and commercial epi-fluorescent microscopy
• Knowledge or experience of cellular biology and cancer biology

To apply: Please include your resume and cover letter.

UBC Job Reference: JR6711

A Computational Biologist position is available in Dr. Martin Hirst’s Epigenomics lab in the Department of Microbiology and Immunology, University of British Columbia, Canada.

The main focus of the research in the Hirst lab is directed at understanding the role of epigenetics in cancer and investigating the therapeutic potential of interventions directed at epigenetic processes through a combination of innovative molecular biology and computational techniques. The lab is part of many national and international cancer research initiatives, including Marathon of Hope Cancer Centres Network and Canadian Epigenetics, Environment and Health Research Consortium.

The successful candidate will be embedded within a team of experimental and computational biologists and have access to a state-of-the-science epigenomic mapping pipeline and an extensive collection of reference epigenomic datasets from normal tissues, primary cancer tissues and cells and models.

This position is ideally suited to a creative individual with a strong interest in the operation and management of cutting-edge software for biological applications within an academic setting. The incumbent will be responsible for data management, conversion and analysis of next-generation sequence datasets using open source informatic tools. 

For more detailed information about the research in the Dr. Hirst’s lab, please see http://hirstlab.msl.ubc.ca/. To find out more about Dr. Hirst, including his position as Head of Epigenomics and Distinguished Scientist at Canada’s Michael Smith Genome Sciences Centre, please see https://www.bcgsc.ca/martin-hirst-phd.

Duties and Responsibilities

• Operating and improving a state of the art next generation sequencing data analysis pipeline.
• Tracking and informatics management of large volumes of data with data footprints of up to 100Gb per experiment.
• Performing sequence alignments, file merges and quality filtering using standardized tools.
• Converting sequence alignments to normalized read densities and performing pairwise differential analysis. 
• Contributing to scientific grant proposals, presentations and publications.

Qualifications

• Experience working in a Unix environment, including experience with shell scripting and common command-line tools.
• Expertise in one or more scripting language(s) (e.g. Python, Perl, R, awk, C).
• Familiarity with the development and maintenance of relational databases.
• Experience working with next-generation sequencing data and tools would be an asset (i.e. tools for alignment and variant-calling).
• Experience with statistical software, software testing, and cluster computing would also be assets.

Apply

Applicants should apply through this link (UBC Job opening ID: JR6711).

Posting End Date: April 8, 2022

PLEASE NOTE: The successful candidate will be a UBC employee working at Dr. Hirst’s lab on campus. UBC regulations regarding vaccine status and remote work will apply.

Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.

All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.

Job Reference No. RA1/2_R00003/4_Holt Lab_2022_03_07

Canada’s Michael Smith Genome Sciences Centre (GSC) is seeking a Research Technician to assist in conducting a 12-month, industry-facing, translational research project to validate the commercial potential of a high-throughput platform for the discovery and characterization of therapeutic T cell receptors (TCRs).

Tope-seq, developed by Dr. Robert Holt and his research team, is a patented cell-based assay that allows TCR reactivity to be screened in vitro against T cell antigen libraries expressed in synthetic antigen presenting cells. This allows TCR reactivity to be characterized in both a high-throughput and functionally-relevant manner; a combination of capabilities unmatched by current and emerging technologies. The Tope-seq platform aims to de-risk the development of TCR-based immunotherapies by increasing the likelihood that they achieve success in clinical trials, and ultimately, save lives.

The goal of this objective-based project is to use a series of defined experiments to generate data that will be critical in the further development of the Tope-seq platform, and its translation to a commercial environment.

Project areas: Immunogenomics, T cell biology, engineered cell therapy, and synthetic biology.

Duties and Responsibilities

As a Research Technician on the Tope-seq project, you will report to Dr. Robert Holt and the Tope-seq Team. Your typical duties will be to perform SOP-driven activities that include the following:

• Maintaining engineered cell lines.
• Assisting in the generation of molecular tools and viral vectors.
• Assisting in high-throughput T cell receptor profiling screens.
• Assisting in the characterization and validation of novel discoveries stemming from high-throughput screening studies.
• Reporting research methods and results in team meetings.

Qualifications

The ideal candidate should possess a MSc degree, or BSc degree with 3+ years of experience, and experience in immunology, genomics, cell biology or a related discipline.

Experience in recombinant DNA technologies and viral gene delivery vectors, mammalian cell culture (including primary T cell culture), and the preparation of Illumina sequencing libraries is desired. Familiarity with flow cytometry/FACS and cell-based assays (such as ELISPOT) will be an asset.

Experience working on focused objective-based research projects and a track record of success in team-based environments is highly desirable.

Position and compensation will be commensurate with experience.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No. RA1/2_R00003/4_Holt Lab_2022_03_07 in the subject line of your email.

This posting will remain online until filled.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No. CBDBDev_P01067_HSA123442_BioApps_2022_03_03

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you have a computer science degree and experience in database programming and design—along with an interest in research science and motivation to contribute to efforts toward improving the lives of cancer patients—consider joining our team at the GSC!

The GSC’s Computational Biologist provides database planning, development and maintenance to support our core sequence pipelines. Duties include analysis, dissemination, as well as storage management and compression, of over 5Pb of internally generated sequencing data.

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on the development of robust, cost efficient, and competitive processes for new targeted and precision medicine analytical pipelines. By working within the GSCs bioinformatics facility, you will develop close relationships with world-renown computational and genome science technologists, cancer researchers and medical scientists; have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. Your work will help to save lives and contribute to a world free from the fear of cancer.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities. Apply now!

Duties and Responsiblities

• Assists in development and maintenance of the core sequence analysis pipelines at GSC, including but not limited to:
  • QC of sequencing data.
  • Alignment of sequenced reads.
  • Formatting and manipulation of alignment files for use by downstream pipelines (e.g. merging, reheadering).
  • Dissemination of data to collaborators.
  • New analyses pipelines as required.
• Assists in development and maintenance of GSC laboratory, quality and analysis databases, including:
  • Routine database integrity checks and database maintenance.
  • Development of views and interfaces for data entry.
  • Development of reports for internal users and collaborators.
  • Investigation of new frameworks and designing new schemas and tables.
• Communicates with stakeholders in the lab, on analysis teams and with external collaborators to understand and document requirements for development and to respond to questions about collaborator data and data quality.
• Works with upstream and lab teams generating data to be housed in the database, and with downstream users of the databases to meet requirements, and responds to internal requests for query and API support.
• Participates in the development and maintenance of ETL pipelines between GSC production databases.
• Manages the storage and compression of over 5Pb of internally generated sequencing data as well as the download and storage of external data.
• Works closely with GSC Systems team and Quality Assurance team to establish and carry out best practices for data security and ensure compliance with ISO 27001 certification, CAP/DAP clinical accreditation requirements and other data use agreements.
• Tests and validates new data analysis software for analyses such as alignment, duplicate marking and merging.
• Participates in code walk-throughs and reviews of solutions.
• Participates in designing and building database solutions, taking performance into consideration.
• Coordinates production problem resolution for assigned applications, including working with other technical teams.
• Produces thorough but concise written documentation of database tables, applications, validations, SOPs and other processes and procedures as required.
• Performs other related duties as required.

Qualifications

Education, Training and Experience

• Graduation from a recognized Bachelor of Science Program in Computer Science or equivalent with significant computer science components. 
• Two years of recent related experience or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

• Experience in SQL, database programming and database design.
• Demonstrated ability in Python, Javascript, or other high level programming language
• Experience with REST API development.
• Experience with front-end web development (React.js, Javascript). Functional knowledge of distributed version control systems, such as GIT.
• Experience developing software as part of a team and familiarity with Agile development and ticketing systems.
• Comfortable working in an Unix environment, including experience with shell scripting and common command-line tools.
• Excellent verbal and written communication skills.
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
• Demonstrated ability to efficiently organize work assignments and establish priorities.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No. CBDBDev_P01067_HSA123442_BioApps_2022_03_03 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

JOB SUMMARY

COVID NOTE: UBC currently requires 20% of time to be spent in person, thus semi-remote.  Due to the worksite being in a hospital facility, up to date vaccinations are required.

A UBC AAPS position is open immediately for a biostatistician to join the Aparicio Lab at BC Cancer. We are seeking a creative, experienced, and dedicated individual to play a key role in developing and maintaining our cancer genomics bioinformatics workflows, housed both on-premise and in cloud infrastructure. The successful candidate will join Dr. Aparicio’s breast cancer Molecular Oncology group, and work as part of the lab’s analysis team alongside other software developers, medical researchers and bioinformaticians.  As part of the team, you will help find and develop computational solutions for problems faced by medical researchers and students in the lab, assisting them in pushing the scientific edge of cancer genomics research. Experience with survival analysis and clinical studies statistical analysis will be an advantage.

The efforts of the research group have yielded important and insightful advances in understanding of tumour evolution, specifically how cancers initiate, develop and acquire resistance to treatment. Development of software platforms to address these questions are used both internally and more widely by world-leading scientists studying cancer. More info on the research and the team we conduct can be found here: https://aparicio.molonc.ca

ORGANIZATIONAL STATUS

Working in the computational team, independently carrying out statistical analyses tasks under the instructions and oversight of the team lead or designate. 

WORK PERFORMED

• Collaborate with researchers to determine study design
• Performs statistics analyses for new and ongoing studies, including but not limited to analysis of drug sensitivity, gene expression and IHC
• Review protocols and methodologies to ensure they adhere to best statistical practices
• Visualize and display study data for interpretation and publication
• Provide consultation and training to other data analysts and researchers
• Create user-friendly scripts and programs to assist in data analysis
• Contribute to writing manuscripts and scientific presentations
• Leave comprehensive and robust documentation for protocols and scripts

CONSEQUENCE OF ERROR

Accountable for the generation and maintenance of quality protocols and results that will have significant research progress implications.

SUPERVISION RECEIVED

Supervision from team lead or designate. Results reviewed monthly and annually for achievement of overall objectives.

SUPERVISION GIVEN

May help supervise undergraduate trainees and/or researchers.

QUALIFICATIONS

Education, training and experience:

• Ph.D in Statistics or Biostatistics is preferred, but we will consider M.Sc in the same degrees with relevant work experience
• Demonstrated proficiency with statistical methods and applications in clinical research

Core skills and abilities:

• Up-to-date knowledge of statistical methodologies related to areas such as drug sensitivity, statistical modeling, survival, and clinical analysis.
• Competence in R and/or SAS programming language
• Familiarity with the development, testing, and maintenance of academic open source code
• Excellent verbal and written communication skills
• Demonstrated ability to efficiently organize work assignments and establish priorities
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment

Optional assets:

• Familiarity with genomics and bioinformatics
• Familiarity with molecular and cellular biology

To apply: please include your resume and cover letter.

Canada’s Michael Smith Genome Sciences Centre (GSC) is seeking a Senior Research Assistant to conduct a 12-month, industry-facing, translational research project to validate the commercial potential of a high-throughput platform for the discovery and characterization of therapeutic T cell receptors (TCRs).

Tope-seq, developed by Dr. Robert Holt and his research team, is a patented cell-based assay that allows TCR reactivity to be screened in vitro against T cell antigen libraries expressed in synthetic antigen presenting cells. This allows TCR reactivity to be characterized in both a high-throughput and functionally-relevant manner; a combination of capabilities unmatched by current and emerging technologies. The Tope-seq platform aims to de-risk the development of TCR-based immunotherapies by increasing the likelihood that they achieve success in clinical trials, and ultimately, save lives.

The goal of this objective-based project is to use a series of defined experiments to generate data that will be critical in the further development of the Tope-seq platform, and its translation to a commercial environment.

Project areas: Immunogenomics, T cell biology, engineered cell therapy, and synthetic biology.

Duties and Responsibilities

As Senior Research Assistant on the Tope-seq project, you will report to Dr. Robert Holt and the Tope-seq Team. Your duties will be to lead SOP-driven activities that include the following:

• Constructing cell libraries for high-throughput screening experiments.
• Performing high-throughput T cell receptor profiling screens.
• Characterizing and validating novel discoveries stemming from high-throughput screening studies.
• Reporting research methods and results in meetings.
• Contributing toward SOP development.
• Contributing to scientific publications, patents, and funding proposals as needed.

Qualifications

The ideal candidate should possess a PhD degree, or MSc degree with 5+ years of experience, and recent experience in immunology, genomics, cancer biology, cell biology or a related discipline.

Experience in recombinant DNA technologies and viral gene delivery vectors, mammalian cell culture (including primary T cell culture), flow cytometry/FACS, and cell-based assays (such as ELISPOT) is desired. Familiarity with 2^nd and 3^rd generation DNA sequencing platforms (including single-cell sequencing platforms) will be an asset.

Experience working on focused objective-based research projects and a track record of success in team-based environments is highly desirable. Due to the translational nature of this research project, an interest or aptitude for technology development and/or commercialization would be a valuable asset. 

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference RA3-Holt Lab in the subject line of your email.

This posting will remain online until filled.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Canada’s Michael Smith Genome Sciences Centre (GSC) is seeking a Post-doctoral Fellow to conduct a 12-month, industry-facing, translational research project to validate the commercial potential of a high-throughput platform for the discovery and characterization of therapeutic T cell receptors (TCRs).

Tope-seq, developed by Dr. Robert Holt and his research team, is a patented cell-based assay that allows TCR reactivity to be screened in vitro against T cell antigen libraries expressed in synthetic antigen presenting cells. This allows TCR reactivity to be characterized in both a high-throughput and functionally-relevant manner; a combination of capabilities unmatched by current and emerging technologies. The Tope-seq platform aims to de-risk the development of TCR-based immunotherapies by increasing the likelihood that they achieve success in clinical trials, and ultimately, save lives.

The goal of this objective-based project is to use a series of defined experiments to generate data that will be critical in the further development of the Tope-seq platform, and its translation to a commercial environment.

Project areas: Immunogenomics, T cell biology, engineered cell therapy, and synthetic biology.

Duties and Responsibilities

As a Post-doctoral Fellow on the Tope-seq project, you will report to Dr. Robert Holt and the Tope-seq Team. Your typical duties will include the following:

• Designing cell libraries for high-throughput screening experiments.
• Performing high-throughput T cell receptor profiling screens.
• Characterizing and validating novel discoveries stemming from high-throughput screening studies.
• Reporting research methods and results in meetings.
• Contributing to the scientific advancement of the Tope-seq platform
• Contributing to scientific publications, patents, and funding proposals as needed.

Qualifications 

The ideal candidate should possess a PhD degree and recent experience in immunology, genomics, cancer biology, cell biology or a related discipline.

Experience in recombinant DNA technologies and viral gene delivery vectors, mammalian cell culture (including primary T cell culture), flow cytometry/FACS, and cell-based assays (such as ELISPOT) is desired. Familiarity with 2^nd and 3^rd generation DNA sequencing platforms (including single-cell sequencing platforms) will be an asset.

A strong publication record and a track record of success in objective-based research projects are highly desirable. Due to the translational nature of this research project, an interest or aptitude for technology development and/or commercialization would be a valuable asset. 

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference PDF-Holt Lab in the subject line of your email.

This posting will remain online until filled.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No. AA2_E01823_Admin_2022_02_08

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you have a post-secondary administrative assistant/secretarial diploma and experience providing support for senior level management, consider joining our administration team!

The Administrative Assistant provides confidential administrative and secretarial support to the designated Senior Leader(s) and assists with the activities of the program/services including workload support and organization-wide activities, relevant human resource actions and subsequent projects and taking direction from other designated personnel as appropriate. The Administrative Assistant follows administrative policies and procedures and works independently with minimal direction to balance priorities and workflow. The Administrative Assistant interacts with senior leaders, managers/directors and administrative support staff across the organization to convey information and professionally represent the interests of the department/senior leader utilizing strong persuasion and communication abilities and the exchange of information. The Administrative Assistant determines courses of action from established alternatives to make decisions that will have a positive impact in the program/service and exercises initiative, judgment and problem-solving skills to complete confidential, time-sensitive work. Judgments affect the accuracy and acceptability of further processes or services in the organization.

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on developing and applying genome sequencing technology to a variety of initiatives, including the creation of novel strategies for preventing and diagnosing cancers and other diseases. In supporting our senior management and researchers, you will be helping to save lives and contribute to a world free from the fear of cancer.

We offer a competitive salary, excellent benefits and significant career development opportunities. Apply now!

Duties and Responsibilities

• Provides administrative support that respects confidentiality and ensures that administrative matters are organized and dealt with in a professional manner.
• Prepares documents including presentations, spreadsheets, correspondence, meeting minutes and reports in an accurate and timely manner. Utilizes a variety of software applications to ensure professional standards are maintained, relevant and current data is used and end product is appropriately and professionally formatted. Compiles information into structured reports.
• Maintains a consistently updated and accurate appointment schedule for the senior leader and others as required. Coordinates meetings ensuring well-defined and timely agendas, identification of and notification to interested parties, compilation of background information and supporting materials and preparation of packages/summary documents to assist in decision making and meeting facilitation. Makes catering, travel and accommodation arrangements. Attends meetings and in-services as required.
• Designs and maintains filing and distribution systems for a variety of records and files including confidential information, such as personnel files, payroll files, financial information and other sensitive documents relating to the management of the Department using methods that can be easily accessible to assigned staff.
• Assists in budget development ensuring information is current and accurately compiled, monitors expenditures, ensures invoices are authorized to predetermined amounts and analyzes and reports variances for multiple departments/programs. Completes purchase requisitions/online purchasing and forwards for processing and ensures invoices are authorized for payment and submitted for payment.
• Completes and submits timekeeping records, vacation entitlements and responds to related queries from departments such as Finance, Payroll and Human Resources.
• Provides work direction and guidance to support staff as needed to ensure administrative needs of the area are met.
• Participates in the development and maintenance of administrative and clinical policies and helps to ensure all staff are aware of and adhere to policies and procedures.

Qualifications

A level of education, training and experience equivalent to graduation from a recognized post-secondary administrative assistant/secretarial program, additional course work in advanced word processing, spreadsheet, and database applications, and four (4) years’ progressive experience supporting senior level management.

• Demonstrated ability to work both independently and collaboratively, resolve administrative issues/problems, prioritize workload, and to be flexible to meet and adapt to changes in organizational priorities.
• Demonstrated ability to use Microsoft Office applications, including word processing, spreadsheet and presentation software, at an advanced level.
• Organizational skills and ability to prioritize workload and work under time pressures to meet deadlines.
• Demonstrated ability to communicate effectively both verbally and in writing, including the ability to respond professionally, courteously, and in a clear manner. Demonstrated interpersonal and time management skills. Demonstrated ability to record and transcribe minutes of meetings. Ability to type 60 w.p.m.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No. RPC_R00022_Admin_2022_02_01 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.:  GST_P00634_HSA 121717_Biospec Core_2022_01_28 – Permanent, full time

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you have a diploma in Biotechnology, Microbiology or Biochemistry and experience working in a research lab, join our team as a Genome Science Technologist!  

At the GSC, Genome Science Technologists perform various molecular biology techniques and procedures using laboratory robots. This includes biospecimen procurement, sample handling and quality control, diverse library construction and high throughput sequencing methods.

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on the development of robust, cost efficient, and competitive processes for new targeted and precision medicine analytical pipelines. By working within the GSCs biospecimen core, you will develop close relationships with world-renown specialists in bioinformatics, cancer researchers and medical scientists; have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. Your work will help to save lives and contribute to a world free from the fear of cancer.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

Apply now!

Duties and Responsibilities

1. Following controlled laboratory procedures, performs tasks such as biospecimen receipt and quality check, laboratory information management system (LIMS) data entry, RNA and DNA purification, cDNA synthesis, genome and transcriptome next generation library construction and sequencing, Polymerase Chain Reaction (PCR) experiments and agarose gel electrophoresis.
2. Works within a regulated quality system including maintaining training records, document control with active corrective and preventative actions (CA/PA).
3. Data entry using laboratory software and basic reporting of results to supervisors.
4. Prepares solutions following standard operating procedures.
5. Maintains general lab and equipment cleanliness.  Recognizes and reports malfunctions in equipment.
6. Processes patient samples according to established procedures for clinical sequencing diagnostic tests.
7. Performs other related duties as required.

Qualifications

Education, Training and Experience

Graduation from a recognized diploma program in Biotechnology, Microbiology or Biochemistry 

- OR -

An equivalent combination of education, training and experience acceptable to the Genome Sciences Centre Group Leaders and Production Coordinators.

Skills and Abilities

• Knowledge of molecular biology techniques, particularly DNA and RNA preparation and manipulation, and a good understanding of genomics technologies.
• Demonstrated ability to perform detailed procedures reproducibly and accurately.
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
• Demonstrated ability to efficiently organize work assignments and establish priorities.
• Basic knowledge of and ability to operate personal computers.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No.:  GST_P00634_HSA 121717_Biospec Core_2022_01_28 – Permanent, full time in the subject line of your email.

This posting will remain online until filled.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Job Reference No.:  GST_P00634_HSA 121716_Biospec Core_2022_01_28 – Temporary replacement

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you have a diploma in Biotechnology, Microbiology or Biochemistry and experience working in a research lab, join our team as a Genome Science Technologist!  

At the GSC, Genome Science Technologists perform various molecular biology techniques and procedures using laboratory robots. This includes biospecimen procurement, sample handling and quality control, diverse library construction and high throughput sequencing methods.

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on the development of robust, cost efficient, and competitive processes for new targeted and precision medicine analytical pipelines. By working within the GSC's Biospecimen Core, you will develop close relationships with world-renown specialists in bioinformatics, cancer researchers and medical scientists; have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. Your work will help to save lives and contribute to a world free from the fear of cancer.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

Apply now!

Duties and Responsibilities

1. Following controlled laboratory procedures, performs tasks such as biospecimen receipt and quality check, laboratory information management system (LIMS) data entry, RNA and DNA purification, cDNA synthesis, genome and transcriptome next generation library construction and sequencing, Polymerase Chain Reaction (PCR) experiments and agarose gel electrophoresis.
2. Works within a regulated quality system including maintaining training records, document control with active corrective and preventative actions (CA/PA).
3. Data entry using laboratory software and basic reporting of results to supervisors.
4. Prepares solutions following standard operating procedures.
5. Maintains general lab and equipment cleanliness.  Recognizes and reports malfunctions in equipment.
6. Processes patient samples according to established procedures for clinical sequencing diagnostic tests.
7. Performs other related duties as required.

Qualifications

Education, Training and Experience

Graduation from a recognized diploma program in Biotechnology, Microbiology or Biochemistry 

-OR- 

An equivalent combination of education, training and experience acceptable to the Genome Sciences Centre Group Leaders and Production Coordinators.

Skills and Abilities

• Knowledge of molecular biology techniques, particularly DNA and RNA preparation and manipulation, and a good understanding of genomics technologies.
• Demonstrated ability to perform detailed procedures reproducibly and accurately.
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
• Demonstrated ability to efficiently organize work assignments and establish priorities.
• Basic knowledge of and ability to operate personal computers.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No.:  GST_P00634_HSA 121716_Biospec Core_2022_01_28 – Temporary replacement in the subject line of your email.

This posting will remain online until filled.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No. RPC_R00022_Admin_2022_02_01

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you have experience as a senior administrator in a research or scientific environment—plus a desire to contribute toward improving the lives of cancer patients—join us at the GSC as our Administration Team Lead!

The Team Lead of Administration provides support to the Director of the GSC. Working in collaboration with Administrative Employee Relations, Finance, Projects and Laboratory Operations teams, the successful candidate will ensure administrative and management functions operate efficiently to support GSC operations and processes, and to comply with financial reporting requirements in a grant-funded setting.

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on developing and applying genome sequencing technology to a variety of initiatives, including the creation of novel strategies for preventing and diagnosing cancers and other diseases. In supporting the GSC Director, you will develop close relationships with world-renown computational and genome science technologists, cancer researchers and medical scientists. Your work will help to save lives and contribute to a world free from the fear of cancer.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

What are you waiting for? Apply now!

Duties and Responsibilities

• Assistant to the Director including calendar management, travel and conference arrangements for the Principal Investigator (PI) and his lab members.
• Maintain the Director’s curriculum vitae and biosketches. Prepare CVs for grant applications including Canadian Common CV, UBC CV and other formats of CV required by granting agencies.
• Assist the PI’s trainees with their academic requirements.
• Provide leadership, supervision, training and guidance to administrative staff.
• Responsible for the recruitment and selection process for administrative staff.
• Responsible for managing reporting administrative staff’s performance and attendance issues.
• Perform annual performance reviews of reporting administrative staff.
• Develop and implement procedures to streamline admin processes, including regular review/update of the Admin Master Guidebook, and upkeep of vendor accounts for stationery/office supplies, courier companies, printing companies, hotels, etc.).
• Chair the monthly Administrative team meetings.
• Create and renew UBC Campus Wide Login guest accounts for GSC staff on behalf of PI.
• Holder of, and responsible for reconciling corporate credit card on behalf of PI.
• Coordinate and gather materials for award nominations for scientific / clinical staff on behalf of PI.
• Act as Admin delegate to the GSC Incident Management Team.

Qualifications

• A minimum of 5 years recent related experience in a senior administrative role in a research/scientific environment, including 3 years of supervisory experience.
• Demonstrated knowledge of confidentiality principles as related to research.
• Demonstrated organizational skills and ability to prioritize and exercise initiative.
• Excellent interpersonal, verbal and written communication skills including demonstrated ability to communicate with tact and diplomacy.
• Ability to work as a team member while supervising and leading team.
• Demonstrated computer literacy (Microsoft Word, Excel, PowerPoint, Visio).
• Demonstrated experience with performing detailed administrative duties with minimal direction and strong attention to detail and accuracy of work.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No. RPC_R00022_Admin_2022_02_01 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.; RA_R00006_Jones Lab_2021_09_28

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. We are currently looking for a Research Associate to work on the Genome Canada funded LSARP, “Canada’s Earth BioGenome project”. 

The successful incumbent will work with the project team to lead the activities on the development, application and validation of novel approaches and workflows in the area of integrated de novo genome assembly over multiple sequencing technologies. They will develop automated bioinformatics workflow as well as assembly submission. They will also work closely together with Earth BioGenome Project (EBP) consortium on the sequencing and assembly standards. They will work with Project Leaders to ensure all scientific milestones are achieved and contribute to progress reporting as required. There will be expectations to represent the project within the global EBP consortium and the development of outreach materials and website information. Opportunities will exist for further research on the genomic information developed and for scholarly publication.​

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on improving genome sequencing technology, interpretation and application. By working within Dr. Steven Jones' lab at the GSC , you will develop close relationships with world-renown specialists in bioinformatics and have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. 

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities. Apply now!

Duties

• Work with multidisciplinary scientists at the GSC and collaborators to analyze whole genome and transcriptome sequence data and set up collaborative working plans.
• Develop and maintain bioinformatic pipelines for genome assembly and data analysis.
• Produce written documentation of algorithms, validations, SOPs and other processes related to pipeline updates and procedures as required.
• Present results of bioinformatics software testing internally and externally.
• Perform literature searches, testing and validation of new data analysis software related to bioinformatics pipelines.
• Perform other related duties as required.

Qualifications

• Expertise in bioinformatics, emphasizing genome sequence analysis and gene annotation.
• Knowledge and experience using scientific tools, technologies and online resources as pertaining to de novo genome assembly.
• Fluency in multiple programming languages, including Python, Javascript and SQL.
• Expertise developing and operating in a UNIX/Linus environment and writing shell scripts.
• Experience developing custom scripts and pipelines using high performance computing and other available tools. Pipelines may include de novo assembly, annotation, database query, pan-genome construction and visualization tools, RNA-seq and phylogenetic tree reconstruction.
• Previous API development projects using Open API or Rest API is a plus.
• Excellent communication and organization skills, and ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
• Ability for critical thinking and independent learning.
• Experience in a supervisory role is an asset.  

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RA_R00006_Jones Lab_2021_09_28 in the subject line of your email.

This position will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: PDF_01553_Jones Lab_2021_10_01

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. We are currently looking for a Post-Doctoral Fellow to work on the Genome Canada funded LSARP, “Canada’s Earth BioGenome project”. 

The successful incumbent will work with the project team to lead the activities on the development, application and validation of novel approaches and workflows in the area of integrated de novo genome assembly over multiple sequencing technologies. They will develop automated bioinformatics workflow as well as assembly submission. They will also work closely together with Earth BioGenome Project (EBP) consortium on the sequencing and assembly standards. The successful incumbent will work with project leaders to ensure all scientific milestones are achieved and contribute to progress reporting as required. There will be expectations to represent the project within the global EBP consortium and the development of outreach materials and website information. Opportunities will exist for further research on the genomic information developed and for scholarly publication.​

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on improving genome sequencing technology, interpretation and application. By working within Dr. Steven Jones' lab at the GSC , you will develop close relationships with world-renown specialists in bioinformatics and have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. 

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities. Apply now!

Duties

• Work with multidisciplinary scientists at the GSC and collaborators to analyze whole genome and transcriptome sequence data and set up collaborative working plans.
• Develop and maintain bioinformatics pipelines for genome assembly and data analysis.
• Produce written documentation of algorithms, validations, SOPs and other processes related to pipeline updates and procedures as required.
• Present results of bioinformatics software testing internally and externally.
• Perform literature searches, testing and validation of new data analysis software related to bioinformatics pipelines.
• Perform other related duties as required.

Qualifications

• Knowledge of genomics, genome assembly and genome analysis software.
• Fluency in one or more programming languages, such as Python, Javascript and SQL.
• Experience working in a UNIX/Linus environment and writing shell scripts.
• Previous API development projects using Open API or Rest API is a plus.
• Excellent communication and organization skills and ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
• Ability for critical thinking and independent learning.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using PDF_01553_Jones Lab_2021_10_01 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.: CSS_F00452_HEU121817_Systems_2022_02_01

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you have a technology diploma plus experience with multi-user networks and client/server architecture—along with an interest in research science and motivation to contribute to efforts toward improving the lives of cancer patients—then join our team at the GSC!

The Computer Systems Specialist provides high-end technical support for the GSC information technology infrastructure, including data servers, data network, and client workstations, as well as the website.  Duties include establishing technical standards, designing infrastructure architecture, installing, configuring and upgrading infrastructure components, monitoring infrastructure security and performance, and proactively planning infrastructure enhancements.

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on the development of robust, cost efficient, and competitive processes for new targeted and precision medicine analytical pipelines. By working within the GSCs bioinformatics facility, you will develop close relationships with world-renown computational and genome science technologists, cancer researchers and medical scientists; have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. Your work will help to save lives and contribute to a world free from the fear of cancer.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

What are you waiting for? Apply now!

Duties and Responsibilities

1. Installs, configures, modifies and tests computer hardware used as servers on the GSC network.
2. Installs, configures, and upgrades server software.
3. Designs and implements the GSC network infrastructure, including the design of network topology and the selection and installation of network components.
4. Monitors the security of the information technology infrastructure and its components, including firewalls.
5. Prepares and communicates policies and procedures on security.
6. Develops configuration standards and implementation procedures for network peripherals such as client workstations and network printers.
7. Maintains website hardware and runs webserver software.
8. Creates and maintains mailing groups.
9. Codes, modifies, tests and maintains programs to meet user requirements.
10. Develops GSC wide backup and recovery procedures.
11. Monitors and reports on the performance of all infrastructure components, and responds to and resolves any issues regarding performance.
12. Prepares plans for proactive infrastructure upgrades, including evidence-based reporting on the rationale for such upgrades.
13. Resolves user issues on the technical infrastructure.
14. Provides expert advice on technical issues.
15. Assists with strategic planning on GSC information technology infrastructure, including data, voice and video.
16. Consults with external contacts, including vendors and external partners, on issues regarding technical infrastructure.
17. Performs related duties as required.

Qualifications

Education, Training and Experience

Completion of Grade 12, plus graduation from a recognized two-year systems technology diploma plus three (3) years of recent related experience, which includes experience in:

1. Client/server architecture.
2. Multi-user networked environment.
3. Personal computers.

 Or an equivalent combination of education, training and experience.

Skills and Abilities

• Ability to type.
• Ability to communicate and deal effectively with all levels of staff both verbally and in writing.
• Physical ability to carry out the duties of the position.
• Ability to organize work.
• Ability to operate related equipment.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No.: CSS_F00452_HSA121817_Systems_2022_02_01 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: RPC2_R00026_2021_07_06

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you have a Bachelor's degree in Health Information Science or Computer Science—along with experience in software/system project planning, analysis and implementation—this is your opportunity to join our team as a Business Analyst providing support for cutting-edge technology projects!

Reporting to the Head of Quality and Regulatory Affairs, the Business Analyst and Project Support (BA) leads the analysis and documentation of business requirements to support projects for designated programs and services. The successful candidate for this position will work in close collaboration with other stakeholders to develop business systems enhancements, business solutions, or business processes including GSC’s bioinformatics processes. The BA functions as a Subject Matter Expert to the project team through performing gap analysis of systems and business process mapping including the identification of linkages to other business systems.  

The BA position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on the development of robust, cost efficient and competitive processes for new targeted and precision medicine analytical pipelines. By working within the GSCs bioinformatics facility, you will develop close relationships with world-renown computational and genome science technologists, cancer researchers and medical scientists; have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. Your work will help to save lives and contribute to a world free from the fear of cancer.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

Apply now! 

Duties and Responsibilities

• Provide key contributions to the development of solutions to ensure that business processes and/or project deliverables are consistent, accurate and timely.  
• Participate in and contribute to strategic planning. 
• Develop project plans for the design, development and implementation of new business processes; support the transition from current systems, practices and processes to an integrated system, common practices and standardized processes with current or improved functionality.  
• Ensure key results are achieved in accordance with the project plan by analyzing current business systems and processes, generating ideas and formulating recommendations/options, and supporting members of the project in prioritizing tasks and reaching decisions that are within project scope and timelines. 
• Implement or contribute to the implementation of effective processes to assess project risks, identify risk mitigation strategies and monitor risk throughout the project lifecycle. Support the Managers/Team Leads by providing regular updates on the progress as well as any areas of risk associated with the completion of the project both within the project scope and the timeline. Provide professional expertise to staff, departments, stakeholders, and guidance regarding standard process for project management.
• Coordinate and participate in the analysis, acceptance criteria definition, development, testing, training, implementation and maintenance phases of assigned bioinformatics projects. Carry out post-implementation reviews of systems and make recommendations for improvements.
• Utilize formal data gathering techniques and analysis tools such as flowcharts, diagrams, dashboards, roles and responsibility matrix (RACI) and work effort estimates. Provide details of estimated implementation costs including associated staffing requirements.
• Review, analyze and define current/future state processes, determine user and/or department requirements and contribute to the development of specifications and testing for all identified development, system modifications and installations. Perform impact analyses. 
• Provide user support, advice, guidance and orientation in situations that require interpretation and judgement. Develop content, as required, for training modules; deliver training and provide guidance to system users and department staff. Develop and maintain various business processes, policies and procedures, as well as reference documentation such as user instructions, manuals and reference materials.  
• Provide support to colleagues and users during the development, maintenance and operation of various computer systems by performing duties such as troubleshooting system software problems and testing alternative solutions. 
• Participate in the formal data collection and analysis to help identify system deficiencies and/or operational inefficiencies in order to report and develop new ways of improving business efficiencies including the data analysis related to business case developments, project proposals and other key strategic and transformative initiatives. 
• Assemble, create and maintain information systems technical and operational documentation according to departmental standards.
• Assist with preparation of Requests for Information/Proposal, development of evaluation processes and tools, and evaluation of vendor responses by serving on working groups, documenting detailed requirements and coordinating project team and vendor communications.

Qualifications

• A level of education, training and experience equivalent to a Bachelor's degree in Health Information Science, Computer Science or a related discipline—OR relevant related experience that includes software/system project planning, analysis and implementation.  
• Demonstrated ability to carry out business process mapping and fit gap analysis.  
• Excellent interpersonal, oral and written communication skills with the ability manage multiple interactions with multiple groups while working on multiple issues at the same time.  
• Superior analytical, problem-solving and system analysis skills.  
• Proven ability to plan and execute projects with stringent timelines.  
• Ability to work effectively as part of a team.  
• Demonstrated ability to provide professional expertise to staff, departments and stakeholders, and guidance regarding standard processes for software/computer system related project management.  
• Demonstrated ability to provide user support, advice and training, and other user liaison services.
• Public Service and Health Sector experience and knowledge are an asset.  

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Business Analyst and Project Support in the subject line of your email. 

This posting will remain open until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. 

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.