How to Apply 

Applicants interested in pursuing graduate or postdoctoral training in The Department of Molecular Oncology, please e-mail us directly at careersmolonc@bccrc.ca. Please include the following documents when applying:

  • Cover Letter
  • CV
  • Statement of your research interests and experience 
  • Transcripts 
  • Contact information for two or three references

Research Asst/Tech 3

Job Summary
Researchers in the Department of Molecular Oncology at the BC Cancer Research Institute uses the latest technologies to rapidly identify genes that are involved in the development of cancer. This position will be involved in providing technical support in molecular biology, biochemistry, microscopy and robotics for current on-going research projects in the lab.

Organizational Status
The successful applicant will report to the Principal Investigator or his/her delegate and may assist in overseeing technical work of students and trainees.

Work Performed

  • Plans and performs experiments utilizing complex procedures and/or techniques
  • Processes primary tissue samples
  • Maintain cell cultures using aseptic techniques
  • Provide molecular biology support – DNA and RNA, cloning, extraction/isolation, PCR
  • Provide basic protein biochemistry support – western blotting
  • Experience with antibody labelling is preferred
  • Ability to record data and work with informatics systems that stores and display data is essential
  • Carries out laboratory techniques following standard operating protocols
  • Maintains laboratory records and experimental data; when require summarize results in research reports and lab presentations
  • Performs other related duties as assigned


Consequence of Error/Judgement
The work is of a complex nature, tasks are assigned and the incumbent exercises a considerable amount of responsibility, initiative and judgment in determining own work schedule to achieve those tasks. Non compliance with biosafety and chemical safety regulations may result in closure of facility or loss of grant funding.

Supervision Received
The successful applicant will report to the Principal Investigator or designate.

Supervision Given
Depending on experience and expertise, the successful applicant maybe be required to assist in training of graduate students/trainees including instruction in use of lab equipment and procedures and will troubleshoot experiments in their area of expertise.

Minimum Qualifications
Completion of a relevant technical program or a university degree in a relevant discipline and a minimum three years of related experience or an equivalent combination of education and experience.

 

Preferred Qualifications

  • Working knowledge and understanding of molecular biology and biochemistry techniques is essential, with prior working experience in molecular biology in laboratory setting is considered an asset.
  • Experience with cell culture and aseptic technique preferred.
  • Ability to perform and troubleshoot a wide variety of molecular and cellular biology techniques including the following: RNA / DNA isolation, quantitative PCR, transfection, flow cytometry, immunohistochemistry, ELISA, protein isolation, and western blotting.
  • Preference will be given to applicants with antibody labeling experience.
  • Experience in immunocytochemistry and basic data analysis in R or similar statistics package would be an asset
  • Demonstrated understanding of experimental design and assay optimization.
  • Strong interpersonal skills and the ability to interact positively and productively with other team members are essential.
  • Ability to communicate effectively both orally and in writing.
  • The successful candidate must be well-organized, conscientious, understand the importance of detail, and be able to multi-task and prioritize duties effectively.

To apply: Please send cover letter and resume to careersmolonc@bccrc.ca  – Please put your full name and the job title in the subject line.

Research Asst/Tech 4

Job Summary
Researchers in the Department of Molecular Oncology at the BC Cancer Research Institute uses the latest technologies to rapidly identify genes that are involved in the development of cancer. This senior position will be involved with working on the Single Cell genomics project, in addition, providing general technical support in molecular biology, biochemistry, microscopy and robotics for other current on-going research projects in the lab.

Organizational Status
The successful applicant will report to the Principal Investigator or his/her delegate and may assist in overseeing technical work of students and trainees.

Work Performed

 

Consequence of Error/Judgement
The work is of a complex nature and required high level of training, tasks are assigned and the incumbent exercises a considerable amount of responsibility, initiative and judgment in determining own work schedule to achieve those tasks. Errors may result in the permanent loss of irreplaceable tissue samples, loss of thousands of dollars of material and/or damage to equipment.  Loss of research results could result in the failure of a funded project and put in jeopardy any future funding and the international reputation of the Laboratory. Non compliance with biosafety and chemical safety regulations may also result in closure of facility or loss of grant funding.

Supervision Received
Works under minimum supervision, receiving specific instructions only on unusual problems or when receiving new project outlines from the principal investigator. The successful applicant will report to the Principal Investigator or designate.

Supervision Given
Depending on experience and expertise, the successful applicant maybe be required to assist in training and supervision of graduate students/trainees or junior staff, including providing instruction in use of lab equipment and procedures, and will help troubleshoot experiments in their area of expertise.

Minimum Qualifications
Completion of a university degree in a relevant discipline or technical program and a minimum four years of related experience or an equivalent combination of education and experience. Some positions may require a graduate degree.

Preferred Qualifications

  • Plans and performs experiments utilizing complex procedures and/or techniques.
  • Using of liquid handling robotics and 10x genomics platforms to investigate single cell genomics
  • Visualize and analyse cells using microscopy and flowcytometry.
  • Generation, preparation and submission of Next Generation Sequencing Libraries.
  • Track samples, record data and work with informatics systems that stores and displays data
  • Liaise with collaborators and vendors.
  • Provide technical expertise in molecular biology, protein biochemistry, virology, support and guidance to collaborators and researchers.
  • Data analysis using R script or other basic statistic analysis program
  • Provide molecular biology support – DNA and RNA, cloning, extraction/isolation, PCR Provide basic protein biochemistry support – western blotting
  • Carries out laboratory techniques following standard operating protocols. Maintains laboratory records and experimental data; when require summarize results in research reports and lab presentations.
  • Assist, develop or update Standard Operating Procedures (SOPs) to ensure compliance with regulatory bodies
  • Assist in general maintenance of the lab and receiving and inventory of lab supplies
  • Researches and determines the applicability of new technology and systems related to work
  • Conducts complex analysis and interpretation of data resulting from high throughput experiments.
  • Presents data at scientific meetings, writes reports and contributes to writing ethics and grant applications.
  • Carries out any other related duties as assigned or required in keeping with the qualifications and requirements of this level of technician.
  • Working knowledge and understanding of molecular biology and biochemistry techniques is essential, with prior working experience in molecular biology in laboratory setting is considered an asset.
  • Experience with cell culture and aseptic technique.
  • Ability to perform and troubleshoot a wide variety of molecular and cellular biology techniques including the following: RNA / DNA isolation, quantitative PCR, transfection, flow cytometry, immunohistochemistry, ELISA, protein isolation, and western blotting.
  • Preference will be given to applicants with liquid handling robotics, single cell genomics, Next Generation Sequencing, 10x Genomics experience.
  • Experience in immunocytochemistry and basic data analysis in R or similar statistics package would be an asset
  • Demonstrated understanding of experimental design and assay optimization.
  • Strong interpersonal skills and the ability to interact positively and productively with other team members are essential.
  • Ability to communicate effectively both orally and in writing.
  • The successful candidate must be well-organized, conscientious, understand the importance of detail, and be able to multi-task and prioritize duties effectively

To apply: Please send cover letter and resume to careersmolonc@bccrc.ca  – Please put your full name and the job title in the subject line.

Coordinator, Research Funds Services

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

Reporting to Administrator, Research Business Operations, the Coordinator, Research Funds Services provides research financial reporting and administration on assigned grant funded programs. The responsibilities include monitoring research projects and research grant budgets, coordinating the development and submission of research financial reports, liaising with PHSA restricted funds finance team to ensure grants financial information is accurately maintained, monitoring and tracking receipts and disbursements and assisting with the management, allocation and coordination of  research funds among Partners and Stakeholders.

    

Duties/Accountablilties:

• Monitors research expenditures and reviews and analyzes research financial information of assigned grant funded programs for the Administrator,  Research Business Operations, and Research Project Managers to assist with planning budgets. This includes pulling appropriate research general ledger accounting information, performing review of research accounts and classifying financial information for reporting, invoicing and budgeting purposes. Ensures research budgets remain within allowable spending limits by tracking and monitoring receipts, disbursements and expenses of general accounts. Investigates and identifies errors/discrepancies and creates journal entries to correct accounting records and maintain research financial information integrity.

• Prepares and reviews research purchase orders and expense claims to ensure applicability and correct expense coding. Verifies appropriate back-up provided and ensures compliance with PHSA policy as well as external funding agency policies. Identifies/determines if expense claim is allowable and makes suggestions on alternative options, if necessary. Follows up with vendors on outstanding credits or erroneous billing as well as cheque payment requests and facilitates payment options by ensuring that required information is obtained (cheque payment, wire transfer, credit card, etc.)

• Performs periodic reconciliation of the research general ledger, research corporate card purchases, research capital expenditures, research payroll reports and receivables to ensure accuracy and timely follow-up.

• Prepares research billing invoices based on the general ledger on a weekly, quarterly and ad-hoc basis to ensure timely collection of revenue from external funding agencies. Ensures research payments are received in full and follows-up on outstanding bad debt accounts.

• Communicates internally with Accounts Payable, Accounts Receivable and PHSA Finance and provides direction on account coding to accurately reflect nature of research financial transaction. Monitors and reconciles research shadow accounts held at UBC and SFU by pulling the general ledger held at these institutions to ensure accurate and complete yearly reporting of funding received. Communicates with the universities regarding accounting discrepancies and generates journal entries and/or invoices to reflect accurate research financial information.

• Monitors research reporting/invoicing due dates and coordinates timelines to ensure that deadlines are met. Compiles and prepares research financial reports/invoices as needed (quarterly, yearly, etc.) and ensures that expenditures reported are in compliance with spending guidelines and GAAP (generally accepted accounting principles). Identifies under/over-expenditures and recommends options to ensure that the research project stays within budget.

• Provides support during annual and interim audits by compiling research general ledger information and ensuring proper documentation is kept on file. Provides analysis to identify/explain journal entries as required by the auditor. Coordinates periodic research financial and annual reports as required by granting agencies, PHSA , partner universities and stakeholders to ensure information is summarized according to guidelines.

    

Qualifications:

A level of education, training and experience equivalent to a Diploma in Accounting/Financial Management or pursuing a professional designation program and preferably three (3) years of recent related experience in a multi government institutional setting, including experience working with national and international granting and funding bodies. 

Knowledge and experience in working with General Accepted Accounting Principles (GAAP) in a university/life science environment. Knowledge of grant management and familiarity with granting agencies and their guidelines and policies. Working knowledge of the university/health care funding process and procurement practices is an asset. Demonstrated ability to conduct oneself in a professional and confidential manner.  Demonstrated administrative and organizational skills.  Demonstrated ability to productively use word processing, excel spreadsheets, financial reporting and project/budget management applications.  Demonstrated ability to communicate effectively both verbally and in writing.  Ability to work independently with minimal direction. Ability to handle workload pressures and demonstrated ability to prioritize.  Ability to supervise junior staff.

To apply: Please send cover letter and resume to careersmolonc@bccrc.ca  – Please put your full name and the job title in the subject line.

Postdoctoral fellow, Bioinformatics

Job Summary:

The candidate would work within a dynamic and vibrant lab with a proven track record of outstanding achievements and contributions in breast oncology research. This position allows the candidate to contribute bold and innovative research that can be translated to new understanding in the evolutionary processes that drive cancers.

This position's primary focus in the lab will be to lead and to participate in projects based on candidate's desire concentrated on investigating genetics of breast oncology, cancer evolutionary, and development of novel therapeutics. Using the wide network of connections and collaborations of the principal investigator, and extensive biomedical resources at the institution, candidates will be able to build on the existing research of the lab to quickly start up their own research projects.

The position will provide a unique opportunity for mentoring trainees, supervising analysts and interacting with industry. This is an excellent platform to receive outstanding training to gain the important skills for a successful medical research career in academia or industry.

This funded position with the University of British Columbia, at the BC Cancer Research Centre allows the candidate to flourish under the guidance of an experienced mentor

Organizational Status:

The Postdoctoral Fellow will play a leadership role in the Aparicio lab, and will be reporting directly to Dr. Samuel Aparicio who is the primary investigator of the laboratory.

Work Performed:

  • Management and supervision of trainees;
  • May be involved in recruitment and training of trainees;
  • Performing regular reviews of the relevant literature;
  • Planning and designing of experiments;
  • Analyzing, interpreting and compiling data in study reports, presenting results, and participating in the preparation of scientific manuscripts and grant application packages;
  • Updating Dr. Aparicio and the group on the status of projects during lab meetings, in email correspondence and phone conferences;
  • Managing projects with key academic and industry partners.

Minimum Qualifications:

  • PhD degree in the computer science, bioinformatics or equivalent
  • At least 4 years experience in bioinformatics research
  • Experience in genomics and next-generation sequencing
  • Extensive knowledge of cellular and molecular biology, biochemistry and genetics
  • Experience with cancer research a plus
  • Proven ability to multi-task in a deadline oriented environment with minimal supervision
  • Effective oral and written communication, analytical, and interpersonal skills
  • Excellent organizational skill and ability to learn new skills quickly
  • Ability to work independently and within a team environment.
  • Accuracy and attention to detail required
  • Candidates should demonstrate the ability to work in a highly interdisciplinary environment.

SUPERVISION RECEIVED

  • Works independently under direction of PI, Dr. Samuel Aparicio
  • Opportunities to work collaboratively with Industry partners and other researchers at UBC and globally

SUPERVISION GIVEN

  • Assists and oversees research assistants and students as required
  • Assists and provides guidelines to other research members, as required

How to Apply

Exceptional candidates should submit a cover letter outlining your research interests and fit with the laboratory's research, curriculum vitae, and the names of three referees willing to provide letters of reference.

To apply:  Please send the above documents to careersmolonc@bccrc.ca and put “PDF Bioinformatics Scientist, Aparicio lab” and your family name in the subject line.

Due to the number of resumes we receive, we are unable to confirm receipt of submissions over the phone, or provide the status of the competition. Only shortlisted candidates will be contacted.

Equity and diversity are essential to academic excellence.  An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged.  We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.

All qualified candidates are encouraged to apply; however Canadians and permanent residents will be given priority.

Post-doctoral Fellow Single Cell Genomics, Molecular Biology

A postdoctoral fellowship position is available in the Aparicio lab based at the BC Cancer Research Centre in Vancouver, Canada, collaborating on an exciting project mapping clonal dynamics in human cancers with new single cell methods. 

The Aparicio lab is developing new single cell genome and transcriptome methods for tracking clonal trajectories at single cell level in patients and patient-derived xenografts. The post holder will have the opportunity to interact as part of the international CRUK Grand Challenge IMAXT project, bringing new measurement methods and computational techniques to the 3D reconstruction of tumour and mapping drug sensitivity and drug combinations using sgRNA/CRISPR methods in vivo. The program works closely with the Shah lab computational biology program on the development of new models for single cell data and cancer evolution. Some experience with bioinformatics approaches to biological data and familiarity with handling of genomics data will be an advantage.

How to Apply: Please send the following documents to careersmolonc@bccrc.ca and put “Single Cell Genomics, Aparicio Lab – PDF Position” and your family name in the subject line.

  • Cover Letter
  • Resume
  • Transcript
  • Work Sample

Post-doctoral Fellow

Posting is available immediately for a postdoctoral fellow with experience in cancer bioinformatics to work on an exciting new program developing non-invasive patient genomic monitoring. The successful candidate will have a degree and postgraduate training in bioinformatics, computer science, statistics, or allied subjects, with experience applying modern computational genome analysis methods. The post holder will work jointly with the groups of Dr Samuel Aparicio (UBC and BC Cancer) &  Dr Andrew Roth (UBC Computer Science and BC Cancer) on developing and implementing methods for analysis of genomic sequencing information from plasma and other fluids to monitor tumour burden and provide information for screening of high risk patients. This will be in conjunction with existing work on single cell genome analysis pioneered by the Aparicio and Shah labs in the last 5 years.

How to Apply:
Please send the following documents to careersmolonc@bccrc.ca and put "Post-doctoral Fellow – Aparicio Lab, family name) in the subject line

  • Cover Letter
  • Resume
  • Transcript
  • Work Sample
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