Careers

Staff - Non Union

Job Category

Non Union Technicians and Research Assistants

Job Profile

Non Union Salaried - Research Assistant /Technician 4

 

Job Title

Research Assistant/Tech 4 - Single Cell Genomics / Molecular Biologist

 

Department

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine

 

Compensation Range

$4,558.75 - $5,354.67 CAD Monthly

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

The anticipated start date for this position is Oct 3, 2023. The term is for one year with the possibility of extension.

In your application please include (1) a cover letter, and (2) a CV or resume.

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career. 

Job Summary

The Aparicio lab is developing new single-cell genome and transcriptome methods for tracking clonal trajectories at the single-cell level in patient tissues and to gain a better understanding of the tumour microenvironment. Our researchers use the latest single-cell genomics technologies to rapidly identify genes that are involved in the development of cancer. This position will be working on the Single-Cell Genomics Platform on research projects currently ongoing in the lab. The successful candidate will be providing technical guidance, expertise, technology development and support to both internal/external researchers using the single-cell genomics platform; located at 2 separate research facilities in Vancouver, B.C.

We are seeking a highly-motivated and highly skilled individual with expertise or experience in single-cell genomics, liquid handling robotics, and/or next-generation sequencing with a strong background in molecular biology. The successful applicant will work full-time under the direction and supervision of Dr. Samuel Aparicio, Principal Investigator, and his designate. Individuals with experience using liquid handling robotics are considered an asset. Experience with bioinformatics approaches to biological data and familiarity with the handling of genomics and next-generation sequencing data will be an advantage. This position will provide the candidate with a high leel of exposure to single-cell genomics and translational research, as well as, providing opportunities to work collaboratively with industry partners and other researchers globally; the position start date is flexible.

Organizational Status
Aparicio Lab is located in the department of Molecular Oncology at BC Cancer Research Institute in Vancouver, British Columbia, Canada. The candidate will report directly to Dr. Samuel Aparicio, or Laboratory Research and Operations Manager, in addition, the applicant may assist in overseeing the technical work of students and trainees.

Work Performed

• Plans and performs experiments utilizing established complex procedures and/or techniques for investigating single-cell genomics, involving the use of liquid handling robotics and 10x genomics platforms.
• Collaborates with PI and team members to support the development project pipelines, and technical experiments.   
• Visualize and analyze cells using microscopy and flow cytometry.
• Generation, preparation and submission of next-generation sequencing libraries.
• Using an LMIS system to track and record sample data
• Provide technical expertise and support in molecular biology, protein biochemistry, tissue culture and virology
• Develop and implement standard operating protocols (SOPs).
• Maintains laboratory records and experimental data.
• Assist in general lab maintenance such as reagent preparation, receiving and inventory of lab supplies.
• Conducts complex data analysis and interpretation of data resulting from high throughput experiments.
• Presents data at scientific meetings, writes reports and contributes to writing ethics and grant applications.
• Carries out any other related duties as assigned or required in keeping with the qualifications and requirements of this technician level.

Consequence of Error/Judgement
The work is complex and required a high level of training, tasks are assigned and the incumbent exercises a considerable amount of responsibility, initiative and judgment in determining their work schedule to achieve those tasks. Errors may result in the permanent loss of irreplaceable tissue samples, loss of thousands of dollars of material and/or damage to equipment.  Incorrect decisions or actions may damage the reputation of the laboratory, lead to a loss of credibility in this field, and be financially costly. Noncompliance with biosafety and chemical safety regulations may also result in the closure of the facility or loss of grant funding.

Supervision Received
The successful applicant will work under minimum supervision. From time to time, Principal Investigator or Laboratory Research and Operations Manager may provide specific instructions on unusual problems or new project outlines. This position will report to the Principal Investigator or Laboratory Research and Operations Manager.   

Supervision Given
Depending on experience and expertise, the successful applicant may be required to assist in the training and supervision of graduate students/trainees, junior staff, or external collaborators; including providing instruction on the use of lab equipment and procedures, and will help troubleshoot experiments in their area of expertise.

Minimum Qualifications
Completion of a university degree in a relevant discipline or technical program and a minimum four years of related experience or an equivalent combination of education and experience. Some positions may require a graduate degree.

- Willingness to respect diverse perspectives, including perspectives in conflict with one’s own

- Demonstrates a commitment to enhancing one’s own awareness, knowledge, and skills related to equity, diversity, and inclusion

Preferred Qualifications

• An MSc in Biological Sciences (Molecular Biology or other relevant fields) with work experience in single cell genomics biology, next-generation sequencing or molecular biology, preferred
• Working knowledge and understanding of molecular biology and biochemistry techniques such as next-generation sequencing, PCR, DNA/RNA purification and molecular cloning techniques are essential; prior working experience in next-generation sequencing and library construction is considered a great asset.
• Experience with cell culture and aseptic technique.
• Working hands-on experience in tissue handling and tissue dissociation methods would be an asset.
• Ability to perform and troubleshoot a wide variety of molecular and cellular biology techniques including the following: RNA / DNA isolation, quantitative PCR, transfection, flow cytometry, immunohistochemistry, ELISA, protein isolation, and western blotting.
• Preference will be given to applicants with liquid handling robotics, single-cell genomics, next-generation sequencing, and 10x Genomics experience.
• Experience in immunocytochemistry and basic data analysis in R or similar statistics package would be an asset.
• Demonstrated understanding of experimental design and assay optimization.
• Strong interpersonal skills, communication skills (orally and written) and the ability to interact positively and productively with other team members are essential.
• Excellent documentation and organizational skills.
• Able to multi-task, prioritize and handle multi-project assignments concurrently.
• The successful candidate must be well-organized, conscientious, understand the importance of detail, and be able to multi-task and prioritize duties effectively.

Staff - Non Union

 

Job Category

Non Union Technicians and Research Assistants

Job Profile

Non Union Salaried - Research Assistant /Technician 3

 

Job Title

Research Assistant/Tech 3 - Aparicio

 

Department

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine

 

Compensation Range

$3,982.67 - $4,703.83 CAD Monthly

 

Posting End Date

September 25, 2023

Note: Applications will be accepted until 11:59 PM on the day prior to the Posting End Date above.

Job End Date

Oct 24, 2024

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

The anticipated start date for this position is October 23 , 2023. The term is for one year with the possibility of extension.

In your application please include (1) a cover letter, and (2) a CV or resume.
 

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career. 

Job Summary

The Aparicio lab is developing new single-cell genome and transcriptome methods for tracking clonal trajectories at the single-cell level in patient tissues and to gain a better understanding of the tumour microenvironment. Our researchers use the latest single-cell genomics technologies to rapidly identify genes that are involved in the development of cancer. This position will be working on the Single-Cell Genomics Platform on research projects currently ongoing in the lab. We are seeking a highly-motivated, detailed, organized, and driven individual with an interest or experience in molecular biology, single-cell genomics, liquid handling robotics, and/or next-generation sequencing.

This entry-level position will provide candidates with an opportunity to work and learn within an academic research environment where continual training and learning are greatly encouraged. The core focus of this position will be providing technical assistance/support on molecular biology, tissue culture, next-generation library preparation and the operations of highly sensitive liquid handling robotics to support current internal/external researchers using the single-cell genomics platform. Hands-on training will be provided to the successful candidate.

This position will provide the candidate with a high level of exposure to single-cell genomics and translational research, as well as, providing opportunities to work collaboratively with industry partners and other researchers globally; the position start date is flexible.

Organizational Status
Aparicio Lab is located in the department of Molecular Oncology at BC Cancer Research Institute in Vancouver, British Columbia, Canada. The successful applicant will report to the Principal Investigator or his/her delegate.

Work Performed

• Plans and performs experiments utilizing established SOPs for investigating single-cell genomics, involving the use of liquid handling robotics and 10x genomics platforms

• Visualize and analyze cells using microscopy and flow cytometry.

• Generation, preparation and submission of next-generation sequencing libraries.

• Using an LMIS system to track and record sample data

• Assist and provide support in molecular biology, tissue culture and next-generation sequencing to other senior searchers

• Assist in developing and implementing standard operating protocols (SOPs).

• Maintains laboratory records and experimental data.

• Assist in general lab maintenance such as reagent preparation, receiving and inventory of lab supplies.

• Present experimental data at internal scientific project meetings.

• Carries out any other related duties as assigned or required in keeping with the qualifications and requirements of this technician level.

Consequence of Error/Judgement
The work is complex and required a high level of training, tasks are assigned and the incumbent exercises a considerable amount of responsibility, initiative and judgment in determining their work schedule to achieve those tasks. Errors may result in the permanent loss of irreplaceable tissue samples, loss of thousands of dollars of material and/or damage to equipment.  Incorrect decisions or actions may damage the reputation of the laboratory, lead to a loss of credibility in this field, and be financially costly. Noncompliance with biosafety and chemical safety regulations may also result in the closure of the facility or loss of grant funding.

Supervision Received
The successful applicant will work under general supervision; receives detailed instructions on the assignment of new duties and thereafter only on new or unusual problems. From time to time, Principal Investigator or Laboratory Research and Operations Manager may provide specific instructions on unusual problems or new project outlines. This position will report to the Principal Investigator or Laboratory Research and Operations Manager.  

Supervision Given
Depending on experience and expertise, the successful applicant may be required to assist in the training and supervision of graduate students/trainees, junior staff, or external collaborators; including providing instruction on the use of lab equipment and procedures, and will help troubleshoot experiments in their area of expertise.

Minimum Qualifications
Completion of a relevant technical program or a university degree in a relevant discipline and a minimum three years of related experience or an equivalent combination of education and experience.

- Willingness to respect diverse perspectives, including perspectives in conflict with one’s own

- Demonstrates a commitment to enhancing one’s own awareness, knowledge, and skills related to equity, diversity, and inclusion

Preferred Qualifications

• A BSc or MSc in Biological Sciences (Molecular Biology or other relevant fields) with work experiences in single-cell genomics biology, next-generation sequencing or molecular biology, preferred

• Working knowledge and understanding of molecular biology techniques such as next-generation sequencing, PCR, DNA/RNA purification and molecular cloning; prior working experience in next-generation sequencing and library construction is considered a great asset.

• Experience with cell culture and aseptic technique.

• Working hands-on experience in tissue handling and tissue dissociation methods would be an asset.

• Preference will be given to applicants with liquid handling robotics, single-cell genomics, next-generation sequencing, and 10x Genomics experience.

• Experience in immunocytochemistry and basic data analysis in R or similar statistics package would be an asset.

• Demonstrated understanding of experimental design and assay optimization.

• Strong interpersonal skills, communication skills (orally and written) and the ability to interact positively and productively with other team members are essential.

• Excellent documentation and organizational skills.

• Able to multi-task, prioritize and handle multi-project assignments concurrently.

• The successful candidate must be well-organized, conscientious, understand the importance of detail, and be able to multi-task and prioritize duties effectively.

What you’ll do

• In collaboration with the Principal Investigator(s) (PIs), coordinate the preparation and submission of grant proposals.
• Interact with both national and international universities and granting agencies. Ensure flow of information with internal and external stakeholders regarding grant related matters and make arrangements for visiting speakers and guests.
• Coordinate registration and travel arrangements for staff attendance at seminars and meetings. This includes completing registration (on-line or phone), abstract submission, making travel and lodging reservations, culminating expense reimbursements to the attendee and/or cost recovery from the conference organizers.
• Human resource responsibilities include recruitment of staff by posting/advertising internally and externally (UBC), coordinating interviews and screening applications for review by hiring supervisors. Manage new hire orientation process and ensure all safety and personnel documentation is in place according to policies, guidelines and legislations.
• Ensure all hiring, appointment and payroll processes are complete for employees. Liaise with various PHSA units such as Payroll and Human Resources and in some cases, UBC, to ensure a seamless process and minimize errors.
• Act as the main contact for ordering lab and office supplies for the department. Manage and process various requisitions such as travel, expense reimbursements, cheque requests, and honorariums for the Department Head and PIs. 

 

What you bring

• A level of education, training, and experience equivalent to a Diploma in a relevant area such as business administration or finance from a recognized college.
• Three (3) years’ recent, related experience a research environment and in project management.
• Strong interpersonal and communication skills and the ability to demonstrate good judgment, tact and discretion.
• Demonstrated time management skills and the ability to assist others in meeting deadlines.
• Demonstrated ability to make sound decisions and resolve administrative issues/problems.
• Detail orientation and the ability to complete accurate work in a timely matter.
• Knowledge of and experience with grant applications. Knowledge and experience in budget preparation, tracking expenditures and identifying sources of variance.
• Commitment to upholding the shared responsibility of creating lasting and meaningful reconciliation in Canada as per TRC (2015) and BC's Declaration on the Rights of Indigenous Peoples Act (2019).
• Knowledge of social, economic, political and historical realities impacting indigenous communities and familiarity with Indigenous Cultural Safety and anti-racism and accompanying reports (BC DRIPA, TRC, etc.).

What we bring

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• Enjoy a comprehensive benefits package, including municipal pension plan, and psychological health & safety programs and holistic wellness resources.
• Annual statutory holidays (13) with generous vacation entitlement and accruement.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: Casual

Salary Range: $51,156 - $68,455 per year. The starting salary for this position would be determined with consideration of the successful candidate’s relevant education and experience, and would be in alignment with the provincial compensation reference plan. Salary will be prorated accordingly for part time roles.

Location: 675 W 10th Ave, Vancouver, BC V5Z 1G1

Applications will be accepted until position is filled.

Hours of Work: Monday to Friday; 0830-1630

Requisition # 147998

Job Category:

Faculty Non Bargaining

Job Title:

Research Associate - Bioinformatics

Department:

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine (Samuel Aparicio)

 

Job Summary:

The Aparicio lab is seeking a Bioinformatics Research Associate to join our dynamic and accomplished team, renowned for its contributions to breast oncology research. Our lab's success stems from a combination of technical excellence, hard work, and a global network of outstanding collaborators from Canada, the United States, and the United Kingdom, all working together to advance our understanding of the evolution of breast, ovarian, and other cancers.

As part of the University of British Columbia and the BC Cancer Research Centre, the Aparicio lab benefits from the abundant biomedical resources available at these institutions. These resources have enabled our team to develop expertise in techniques ranging from CRISPR gene editing to spatial imaging and single molecule sequencing. As a result, our trainees have had the opportunity to share their work in esteemed journals like Nature, Nature Cancer, and Cell in recent years.

In this role, the Bioinformatics Research Associate will primarily focus on leading and participating in projects that investigating functional genomics using sequencing and expression data for breast oncology and cancer evolution.

This position offers a unique opportunity for mentoring trainees, supervising staff, and interacting with industry professionals, providing an ideal platform to develop the essential skills for a successful medical research career in academia or industry. As a Research Associate at the University of British Columbia, you will thrive under the guidance of an exceptional mentor within the supportive environment of the BC Cancer Research Centre.

This position is located within a health-care facility. Therefore, this position requires successful verification of full vaccination against COVID-19 provided prior to the start date, as required by the provincial health mandate.

The UBC Department of Pathology and Laboratory Medicine is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients. The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence.

ORGANIZATIONAL STATUS

The researcher associate will play a leadership role in the Aparicio lab, and will be reporting directly to Dr. Samuel Aparicio who is the primary investigator of the laboratory.

WORK PERFORMED

• Planning and designing of experiments;
• Analyzing, interpreting and compiling data in study reports, presenting results, and participating in the preparation of scientific manuscripts and grant application packages
• Updating Dr. Aparicio and the group on the status of projects during lab meetings, in email correspondence and phone conferences;
• Managing projects with key academic and industry partners.
• Performing regular reviews of the relevant literature;
• Management and supervision of trainees;
• May be involved in recruitment and training of trainees;

CONSEQUENCE OF ERROR

Accountable for the management and progress of research projects.  Errors in judgment may cause severe impact to research progress, reputational good standing and international collaborations.

SUPERVISION RECEIVED

Works independently under direction of PI, Dr. Samuel Aparicio Opportunities to work collaboratively with Industry partners and other researchers at UBC and globally

SUPERVISION GIVEN

Assists and oversees research assistants and students as required.  Assists and provides guidelines to other research members, as required

MINIMUM QUALIFICATIONS

• PhD degree in the computer science, bioinformatics or equivalent
• At least 4 years experience in bioinformatics research
• Expertise in next-generation sequencing genomics and transcriptomics
• Demonstrated success in computational academic research
• Proven ability to multi-task in a deadline oriented environment with minimal supervision
• Excellent organizational skill and ability to learn new skills quickly

PREFERRED QUALIFICATIONS

• Extensive knowledge of cellular and molecular biology, biochemistry and genetics
• Experience with cancer research
• Outstanding oral and written communication, analytical, and interpersonal skills
• Ability to work independently and within a team environment.
• The ability to balance a broad strategic vision with attention to detail
• Candidates should demonstrate the ability to work in a highly interdisciplinary environment.

Become a part of our dedicated team as we continue to break new ground in cancer research and translate our findings into meaningful advancements in patient care. Apply now to contribute your skills and enthusiasm to the Aparicio lab, and help shape the future of oncology research.

Academic

 

Job Category

Faculty Non Bargaining

Job Title

Postdoctoral Research Fellow - Single Cell Genomics, drug resistance in cancer

 

Department

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine (Samuel Aparicio)

 

JOB DESCRIPTION:

Post-doctoral Fellow (PDF) Single Cell Genomics, drug resistance in cancer We are seeking a highly-motivated post-doctoral fellow (PDF) with strong leadership ability and expertise in single cell genomics and transcriptomics, and a strong background in molecular biology. The successful applicant will work full-time under the supervision of Dr. Samuel Aparicio on an exciting project decoding the role of epigenomic and genomic drug resistance. The position start date is flexible.

JOB SUMMARY:
The Aparicio lab is developing new single cell genome and transcriptome methods for tracking clonal trajectories at single cell level in patient tissues and patient-derived xenografts (PDX). The lab is highly multidisciplinary and highly productive (Laks et al, Cell 2019, Salehi et al Nature 2021, Funnell et al Nature 2022) and is well funded for single cell analysis of genomes and transcriptomes in cancer. The Aparicio lab is developing new single cell genome and transcriptome methods for tracking clonal trajectories at single cell level in patients and patient-derived xenografts. The project involves collaborating on an exciting project mapping clonal dynamics in human cancers under drug treatment with new single cell methods. The post holder will also have the opportunity to interact as part of the international Welcome LEAP Delta Tissue project and an exciting new program in the biology of epithelium from high risk carriers of BRCA1/BRCA2 mutations. These projects are bringing new measurement methods and computational techniques to the 3D reconstruction of tumours, and mapping drug sensitivity and drug combinations using sgRNA/CRISPR methods in vivo. The program works closely with UBC departments of statistics and computer science and the New York Genome Center NY, on the development of new models for single cell data and cancer evolution. Some experience with bioinformatics approaches to biological data and familiarity with handling of genomics data will be an advantage.

ORGANIZATIONAL STATUS:

Aparicio Lab is located in the department of Molecular Oncology at BC Cancer Research Center in Vancouver, British Columbia, Canada. The candidate will report directly to Dr. Samuel Aparicio, and will play a senior leadership role in the laboratory.

The Department of Pathology and Laboratory Medicine at UBC is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients.  The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence. 

WORK PERFORMED:
● Provide leadership, strategic direction, and translational research pertaining to single cell genomics and transcriptomics, and CRISPR methods.
● Design and implement research plan to investigate the clonal dynamics in human cancer through single cell methods.
● Design and conduct animal experiments.
● Conduct in vivo testing or characterization of drugs, small molecules, knockouts or antibodies in relevant PDX animal models.
● Foster research collaborations and work jointly with academic, clinical, industry, and other partners.
● Scientifically document lab experiments, data analysis, interpretations.
● Write manuscripts, present results at internal and external meetings.
● Identify funding opportunities and if required write or assist with grant proposals
● Lead and mentor junior trainees/students in the laboratory

CONSEQUENCE OF ERROR:
This is a senior research position that plays a critical role in the development of this novel field. PDF is accountable for the quality and integrity of the research and data, including analyses and interpretation, as well as the effective and efficient management of research projects and deliverables. This position requires innovation, strategic planning, and adaptability. Incorrect decisions or actions may damage the reputation of the laboratory, lead to loss of credibility in this field, and be financially costly.

SUPERVISION RECEIVED:

The PDF will work with a high degree of independence and set priorities under broad directives from Dr. Aparicio. The PDF will be expected to provide direction and mentoring in the laboratory under the supervision of Dr. Aparicio. This position will also provide the candidate with a high level of exposure to single cell genomics and translational research, as well as, providing opportunities to work collaboratively with industry partners and other researchers globally.

SUPERVISION GIVEN:

The PDF will be expected to provide mentorship and guidance to undergraduate, graduate students and other research members as required.

QUALIFICATION:
● Ph.D. in biology, cell biology, molecular biology, biochemistry, genetics, genomics, or similar discipline.
● The candidate should have a solid scientific and technical background with excellent written/oral communication, interpersonal and organizational skills.
● Preference will be given to candidates with a proven track record with a minimum of 2-3 first author publications in reputable journals.
● Proficiency in cell biology, molecular biology, histology, genetics, genomics, next-generation sequencing and biochemistry techniques.
● Demonstrate the ability to work in a highly interdisciplinary environment.
● Experience with cancer research.
● Expertise and hands-on experience in animal studies, including all aspects of design, handling, breeding, tissue collection, histology, and analyses are essential.
● Familiarity with testing/characterization of small molecule or drug in vivo is preferred.
● Previous biochemical/cell biology and molecular biology experience with single cell genomics / transcriptomics, next generation sequencing, drugs screen and PDX modeling is an asset.
● Experience with statistical analyses and scientific writing. Previous experience with grant writing is an asset.
● Experience with bioinformatics approaches to biological data and familiarity with handling of genomics data is an asset.
● Applicants with experience and a strong track record with large drug target screening, single cell methods, and PDX mouse models are especially encouraged to apply.

How to Apply:

Exceptional candidates should submit a cover letter outlining your research interests and fit with the laboratory's research, curriculum vitae, and the names of three referees willing to provide letters of reference.

Due to the number of resumes we receive, we are unable to confirm receipt of submissions over the phone, or provide the status of the competition. Only shortlisted candidates will be contacted.

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

UBC hires on the basis of merit and is committed to employment equity. All qualified persons are encouraged to apply.

Equity and diversity are essential to academic excellence.  An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged.  We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, and/or Indigenous person.

We are currently looking for a Postdoctoral Fellow to join Dr. Andrew Roth’s and Dr. Adi Steif’s computational cancer genomics research groups at the BC Cancer Research Institute (BCCRI).

The current position is for a candidate with experience developing and applying computational methods to analyze high throughput biological data. The successful applicant will be part of an exceptional multidisciplinary team developing and applying single cell multiomic methods to study evolution and disease transformation risk in follicular lymphoma (FL). Funded by a multi-year Terry Fox New Frontiers Program Project Grant, the project is a close collaboration with clinicians, molecular biologists and bioinformatic scientists. The candidate will have the opportunity to work with a unique and complex dataset which includes single cell DNA, RNA and epigenetic data.

This is an opportunity to work with highly motivated colleagues in a creative and dynamic environment. By joining the Roth and Steif labs at the BCCRI, you will develop close relationships with world-renown specialists in genomics and bioinformatics and have access to robust computational and sequencing technology facilities, all while living in one of the most beautiful, diverse and eclectic cities in the world.

We offer a competitive salary, excellent benefits and significant career development opportunities

What you’ll do

Working in a multidisciplinary team, the postdoctoral fellow will develop and apply scalable analytical workflows for multiomic data integration and biological interpretation. The appointment is for one year in the first instance, with potential for renewal. Responsibilities include:

• Regularly review the scientific literature
• Contribute to experimental design and planning
• Data preprocessing and quality control
• Data analysis, visualization, and biological interpretation
• Develop and maintain well-documented code
• Regularly update Drs. Roth and Steif as well as key collaborators on the status of projects
• Participate in and present research updates at lab meetings, team meetings and conferences
• Contribute to scientific writing, including the preparation of research manuscripts and grant applications
• May be involved in recruitment, management, and supervision of trainees

What you bring

• A PhD in bioinformatics, computer science, statistics or related discipline
• At least 2 years of research experience in bioinformatics, with a record of first-author publication
• Experience in genomics and high-throughput sequencing data analysis
• Experience in cancer research is an asset
• Programming fluency in Python or R
• Experience working in a Unix/Linux computing environment

You have:

• Critical thinking and attention to detail
• Excellent verbal, written and interpersonal communication skills
• Ability to work independently and in a collaborative interdisciplinary team
• A strong work ethic, with demonstrated ability to manage time and prioritize to meet deadlines
• Commitment to upholding the shared responsibility of creating lasting and meaningful reconciliation in Canada as per TRC (2015) and BC's Declaration on the Rights of Indigenous Peoples Act (2019).
• Knowledge of social, economic, political and historical realities impacting indigenous communities and familiarity with Indigenous Cultural Safety and anti-racism and accompanying reports (BC DRIPA, TRC, etc.).

What we bring

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: Temporary, Casual 
Location: 675 West 10th Avenue, Vancouver BC, V5Z 1G1
Hours of Work: Monday to Friday; 0830-1630
 

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

 

How to Apply

Applicants should submit: a CV; a one-page cover letter explaining how your research experience, interests and career goals align with the position; and the names and contact details of 3 references. 

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

 

What we do

About the GSC:

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The Genome Sciences Centre (GSC) is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics and bioinformatics pursuing novel treatment strategies for cancer and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research.

The GSC is part of BC Cancer Research Institute and the Provincial Health Services Authority (PHSA).

BC Cancer provides comprehensive cancer control for the people of British Columbia.

BC Cancer is part of the Provincial Health Services Authority (PHSA).

(PHSA) plans, manages and evaluates specialized health services with the BC health authorities to provide equitable and cost-effective health care for people throughout the province. Our values reflect our commitment to excellence and include: Respect people – Be compassionate – Dare to innovate – Cultivate partnerships – Serve with purpose.

Learn more about PHSA and our programs: jobs.phsa.ca/programs-and-services

PHSA is committed to employment equity, encouraging all qualified individuals to apply. We recognize that our ability to provide the best care for our diverse patient populations relies on a rich diversity of skills, knowledge, background and experience, and value a safe, inclusive and welcoming environment.

Reconciliation is an ongoing process and a shared responsibility for all of us. The BC Governments’ unanimous passage of the Declaration on the Rights of Indigenous Peoples Act was a significant step forward in this journey—one that all health authorities are expected to support as we work in cooperation with Indigenous Peoples to establish a clear and sustainable path to lasting reconciliation. True reconciliation will take time and ongoing commitment to work with Indigenous Peoples as they move toward self-determination. Guiding these efforts Crown agencies must remain focused on creating opportunities that implement the Truth and Reconciliation Commission Mandate.