When some drugs bind to copper, they have anticancer activity in the lab. However, these copper-drug complexes need to be reformulated for human use. With the support of an Innovation Grant, Dr Marcel Bally developed the first injectable formulation of an anticancer copper-drug molecule. He will now create additional injectable copper-drug treatments based on several other drugs. He will then study the effectiveness of these new treatments in lung and ovarian cancers that resist chemotherapy, selecting the most powerful candidates for further study. This could open the door to new treatment options, especially for hard-to-treat cancers.
Funded by: Canadian Cancer Society Research Institute