Gene-Environment Interactions in Cancer Research (GENIC)

It is known that ultraviolet light exposure causes melanoma. However, it is not clear whether there are other environmental factors acting along with ultraviolet radiation. This study investigates the role of organochlorine compounds, found in the environment, in melanoma development.

This multi- institute project (InterMEL consortium project) identifies molecular and clinical factors which relate to the prognosis of melanoma, with the ultimate objective of improving the treatment of advanced melanoma.

This project aims to discover new markers of breast cancer through an international effort focused on low-penetrance alleles that, in combination, have a high probability of explaining a large proportion of breast cancer risk.

Multiple Myeloma (MM) is generally incurable and patients will eventually develop relapsed/refractory disease. Early relapse is associated with poor clinical outcomes and overall survival. There are currently no effective markers that can predict which patients will have early relapse.