Melatonin, Nightshift Work and DNA Damage (MEND) Study

Melatonin suppression in nightshift workers is associated with reduced ability to repair DNA damage, which may contribute to increased risks of cancer. Dr. Parveen Bhatti is leading a research study to determine if melatonin supplementation can reverse these effects in nightshift workers.

Who can participate?

  • 18- 50 years of age
  • BMI within the range of 18.5- 30
  • Live and work in the Greater Vancouver area
  • Primary work nightshifts at least 7 hours in duration ending no earlier than 6 AM, at least 2-3 nights per week over the past 6 months
  • Sleep at least 4 hours each day after completing a nightshift

Who should not participate in this study?

  • Are currently using melatonin supplements
  • Have a personal history of hormonal disorders, seizure disorders or chronic medical condition
  • Have been diagnosed with sleep disorders
  • Are currently using illicit drugs
  • Are currently pregnant or breast feeding
  • For more details, please read the informed consent page 3

What's involved?

  • Complete questionnaires
  • Donate urine samples
  • Wear a watch-like device to measure sleep quality

What do I do if I am interested?

Complete a 5 minutes screening to interview to determine eligibility

To learn how to volunteer, or set up a screening interview, call 1.604-675.8056 or email at alai@bccrc.ca For those that participate in the study, a token of appreciation for your time will be offered.

Find Study Overview
Back to top