Characterising the molecular changes that underpin the progression and pathogenesis of cancer.

Our Focus

Through the use of cutting edge technologies, Molecular Oncology (MO) aims to identify genes involved in the development of cancer, quickly and accurately.

MO's researchers combine diverse techniques, ranging from genomics, computational biology, tumour imaging, in vitro and in vivo functional models, to study biological and clinical phenotypes. The proteins produced by these genes may serve as targets for novel chemotherapy drugs and other cancer treatments, or imaging scans. MO uses these combined techniques to validate the role of the novel candidate genes in the development of cancer; with an eye towards translating findings into improved treatment options for cancer patients around the world.

News & Events

Dr. David Huntsman awarded Doctors of BC Terry Fox Medal

Pictured above is Dr. Huntsman in St. Johns Newfoundland, near the place where Terry Fox began his run.

The Doctors of BC Terry Fox Medal is awarded to outstanding individuals who have a track record of making a difference in cancer care. We are proud to share that Dr. David Huntsman, distinguished scientist at the BC Cancer Research Institute and professor in the Department of Pathology and Laboratory Medicine at the University of British Columbia, is the recipient of this year’s prestigious award. 
 

Studying six childhood sarcomas to improve survival and life after treatment

With renewed support from a $5.5-million Terry Fox New Frontiers Program Project Grant, leading researchers from BC Cancer and the University of British Columbia (UBC) are determined to change how we understand and treat sarcomas – rare and aggressive bone and soft tissue cancers that disproportionately affect young people.

Canadian and US cancer researchers form special super team to improve treatments and outcomes for patients with osteosarcoma, the rare bone cancer that Terry Fox had

In a national first, a team of top Canadian cancer researchers, including BC Cancer distinguished scientist Dr. Poul Sorensen, is joining forces with world-class US scientists at leading cancer institutes south of the border to tackle together the challenges of osteosarcoma (bone cancer), or what is sometimes called the Terry Fox cancer.

Research Labs

Recent Publications

Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes.

Nature genetics, 2017
Wang, Yi Kan, Bashashati, Ali, Anglesio, Michael S, Cochrane, Dawn R, Grewal, Diljot S, Ha, Gavin, McPherson, Andrew, Horlings, Hugo M, Senz, Janine, Prentice, Leah M, Karnezis, Anthony N, Lai, Daniel, Aniba, Mohamed R, Zhang, Allen W, Shumansky, Karey, Siu, Celia, Wan, Adrian, McConechy, Melissa K, Li-Chang, Hector, Tone, Alicia, Provencher, Diane, de Ladurantaye, Manon, Fleury, Hubert, Okamoto, Aikou, Yanagida, Satoshi, Yanaihara, Nozomu, Saito, Misato, Mungall, Andrew J, Moore, Richard, Marra, Marco A, Gilks, C Blake, Mes-Masson, Anne-Marie, McAlpine, Jessica N, Aparicio, Samuel, Huntsman, David G, Shah, Sohrab P
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Divergent clonal selection dominates medulloblastoma at recurrence.

Nature, 2016
Morrissy, A Sorana, Garzia, Livia, Shih, David J H, Zuyderduyn, Scott, Huang, Xi, Skowron, Patryk, Remke, Marc, Cavalli, Florence M G, Ramaswamy, Vijay, Lindsay, Patricia E, Jelveh, Salomeh, Donovan, Laura K, Wang, Xin, Luu, Betty, Zayne, Kory, Li, Yisu, Mayoh, Chelsea, Thiessen, Nina, Mercier, Eloi, Mungall, Karen L, Ma, Yusanne, Tse, Kane, Zeng, Thomas, Shumansky, Karey, Roth, Andrew J L, Shah, Sohrab, Farooq, Hamza, Kijima, Noriyuki, Holgado, Borja L, Lee, John J Y, Matan-Lithwick, Stuart, Liu, Jessica, Mack, Stephen C, Manno, Alex, Michealraj, K A, Nor, Carolina, Peacock, John, Qin, Lei, Reimand, Juri, Rolider, Adi, Thompson, Yuan Y, Wu, Xiaochong, Pugh, Trevor, Ally, Adrian, Bilenky, Mikhail, Butterfield, Yaron S N, Carlsen, Rebecca, Cheng, Young, Chuah, Eric, Corbett, Richard D, Dhalla, Noreen, He, An, Lee, Darlene, Li, Haiyan I, Long, William, Mayo, Michael, Plettner, Patrick, Qian, Jenny Q, Schein, Jacqueline E, Tam, Angela, Wong, Tina, Birol, Inanc, Zhao, Yongjun, Faria, Claudia C, Pimentel, José, Nunes, Sofia, Shalaby, Tarek, Grotzer, Michael, Pollack, Ian F, Hamilton, Ronald L, Li, Xiao-Nan, Bendel, Anne E, Fults, Daniel W, Walter, Andrew W, Kumabe, Toshihiro, Tominaga, Teiji, Collins, V Peter, Cho, Yoon-Jae, Hoffman, Caitlin, Lyden, David, Wisoff, Jeffrey H, Garvin, James H, Stearns, Duncan S, Massimi, Luca, Schüller, Ulrich, Sterba, Jaroslav, Zitterbart, Karel, Puget, Stephanie, Ayrault, Olivier, Dunn, Sandra E, Tirapelli, Daniela P C, Carlotti, Carlos G, Wheeler, Helen, Hallahan, Andrew R, Ingram, Wendy, MacDonald, Tobey J, Olson, Jeffrey J, Van Meir, Erwin G, Lee, Ji-Yeoun, Wang, Kyu-Chang, Kim, Seung-Ki, Cho, Byung-Kyu, Pietsch, Torsten, Fleischhack, Gudrun, Tippelt, Stephan, Ra, Young Shin, Bailey, Simon, Lindsey, Janet C, Clifford, Steven C, Eberhart, Charles G, Cooper, Michael K, Packer, Roger J, Massimino, Maura, Garre, Maria Luisa, Bartels, Ute, Tabori, Uri, Hawkins, Cynthia E, Dirks, Peter, Bouffet, Eric, Rutka, James T, Wechsler-Reya, Robert J, Weiss, William A, Collier, Lara S, Dupuy, Adam J, Korshunov, Andrey, Jones, David T W, Kool, Marcel, Northcott, Paul A, Pfister, Stefan M, Largaespada, David A, Mungall, Andrew J, Moore, Richard A, Jabado, Nada, Bader, Gary D, Jones, Steven J M, Malkin, David, Marra, Marco A, Taylor, Michael D
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