Characterising the molecular changes that underpin the progression and pathogenesis of cancer.

Our Focus

Through the use of cutting edge technologies, Molecular Oncology (MO) aims to identify genes involved in the development of cancer, quickly and accurately.

MO's researchers combine diverse techniques, ranging from genomics, computational biology, tumour imaging, in vitro and in vivo functional models, to study biological and clinical phenotypes. The proteins produced by these genes may serve as targets for novel chemotherapy drugs and other cancer treatments, or imaging scans. MO uses these combined techniques to validate the role of the novel candidate genes in the development of cancer; with an eye towards translating findings into improved treatment options for cancer patients around the world.

News & Events

Research Labs & Principal Investigators

Recent Publications

Class I HDAC inhibitors enhance YB-1 acetylation and oxidative stress to block sarcoma metastasis.

EMBO reports, 2019
El-Naggar, Amal M, Somasekharan, Syam Prakash, Wang, Yemin, Cheng, Hongwei, Negri, Gian Luca, Pan, Melvin, Wang, Xue Qi, Delaidelli, Alberto, Rafn, Bo, Cran, Jordan, Zhang, Fan, Zhang, Haifeng, Colborne, Shane, Gleave, Martin, Mandinova, Anna, Kedersha, Nancy, Hughes, Christopher S, Surdez, Didier, Delattre, Olivier, Wang, Yuzhuo, Huntsman, David G, Morin, Gregg B, Sorensen, Poul H
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