Characterising the molecular changes that underpin the progression and pathogenesis of cancer.

Our Focus

Through the use of cutting edge technologies, Molecular Oncology (MO) aims to identify genes involved in the development of cancer, quickly and accurately.

MO's researchers combine diverse techniques, ranging from genomics, computational biology, tumour imaging, in vitro and in vivo functional models, to study biological and clinical phenotypes. The proteins produced by these genes may serve as targets for novel chemotherapy drugs and other cancer treatments, or imaging scans. MO uses these combined techniques to validate the role of the novel candidate genes in the development of cancer; with an eye towards translating findings into improved treatment options for cancer patients around the world.

News & Events

Nov 09, 2023

BC Cancer researchers leading the development of immunotherapies targeting the surface protein IL1RAP for the treatment of Ewing sarcoma

Dr. Poul Sorensen, Distinguished Scientist at BC Cancer, in collaboration with Dr. Kevin Hay, Clinician-Ccientist at BC Cancer, and Dr. Wei Li, Assistant Professor at the University of Pittsburgh, received support from the Rutledge Cancer Foundation to develop and optimize novel immunotherapies targeting the surface protein IL1RAP for the treatment of Ewing sarcoma.

Research Labs

Recent Publications

Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma.

Cancer discovery, 2021
Zhang, Hai-Feng, Hughes, Christopher S, Li, Wei, He, Jian-Zhong, Surdez, Didier, El-Naggar, Amal M, Cheng, Hongwei, Prudova, Anna, Delaidelli, Alberto, Negri, Gian Luca, Li, Xiaojun, Ørum-Madsen, Maj Sofie, Lizardo, Michael M, Oo, Htoo Zarni, Colborne, Shane, Shyp, Taras, Scopim-Ribeiro, Renata, Hammond, Colin A, Dhez, Anne-Chloe, Langman, Sofya, Lim, Jonathan K M, Kung, Sonia H Y, Li, Amy, Steino, Anne, Daugaard, Mads, Parker, Seth J, Geltink, Ramon I Klein, Orentas, Rimas J, Xu, Li-Yan, Morin, Gregg B, Delattre, Olivier, Dimitrov, Dimiter S, Sorensen, Poul H
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