Staff - Non Union

Job Category

Non Union Technicians and Research Assistants

Job Profile

Non Union Salaried - Research Assistant /Technician 4

 

Job Title

Research Assistant/Tech 4 - Single Cell Genomics / Molecular Biologist

 

Department

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine

 

Compensation Range

$4,558.75 - $5,354.67 CAD Monthly

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

The anticipated start date for this position is Oct 3, 2023. The term is for one year with the possibility of extension.

In your application please include (1) a cover letter, and (2) a CV or resume.

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career. 

Job Summary

The Aparicio lab is developing new single-cell genome and transcriptome methods for tracking clonal trajectories at the single-cell level in patient tissues and to gain a better understanding of the tumour microenvironment. Our researchers use the latest single-cell genomics technologies to rapidly identify genes that are involved in the development of cancer. This position will be working on the Single-Cell Genomics Platform on research projects currently ongoing in the lab. The successful candidate will be providing technical guidance, expertise, technology development and support to both internal/external researchers using the single-cell genomics platform; located at 2 separate research facilities in Vancouver, B.C.

We are seeking a highly-motivated and highly skilled individual with expertise or experience in single-cell genomics, liquid handling robotics, and/or next-generation sequencing with a strong background in molecular biology. The successful applicant will work full-time under the direction and supervision of Dr. Samuel Aparicio, Principal Investigator, and his designate. Individuals with experience using liquid handling robotics are considered an asset. Experience with bioinformatics approaches to biological data and familiarity with the handling of genomics and next-generation sequencing data will be an advantage. This position will provide the candidate with a high leel of exposure to single-cell genomics and translational research, as well as, providing opportunities to work collaboratively with industry partners and other researchers globally; the position start date is flexible.

Organizational Status
Aparicio Lab is located in the department of Molecular Oncology at BC Cancer Research Institute in Vancouver, British Columbia, Canada. The candidate will report directly to Dr. Samuel Aparicio, or Laboratory Research and Operations Manager, in addition, the applicant may assist in overseeing the technical work of students and trainees.

Work Performed

• Plans and performs experiments utilizing established complex procedures and/or techniques for investigating single-cell genomics, involving the use of liquid handling robotics and 10x genomics platforms.
• Collaborates with PI and team members to support the development project pipelines, and technical experiments.   
• Visualize and analyze cells using microscopy and flow cytometry.
• Generation, preparation and submission of next-generation sequencing libraries.
• Using an LMIS system to track and record sample data
• Provide technical expertise and support in molecular biology, protein biochemistry, tissue culture and virology
• Develop and implement standard operating protocols (SOPs).
• Maintains laboratory records and experimental data.
• Assist in general lab maintenance such as reagent preparation, receiving and inventory of lab supplies.
• Conducts complex data analysis and interpretation of data resulting from high throughput experiments.
• Presents data at scientific meetings, writes reports and contributes to writing ethics and grant applications.
• Carries out any other related duties as assigned or required in keeping with the qualifications and requirements of this technician level.

Consequence of Error/Judgement
The work is complex and required a high level of training, tasks are assigned and the incumbent exercises a considerable amount of responsibility, initiative and judgment in determining their work schedule to achieve those tasks. Errors may result in the permanent loss of irreplaceable tissue samples, loss of thousands of dollars of material and/or damage to equipment.  Incorrect decisions or actions may damage the reputation of the laboratory, lead to a loss of credibility in this field, and be financially costly. Noncompliance with biosafety and chemical safety regulations may also result in the closure of the facility or loss of grant funding.

Supervision Received
The successful applicant will work under minimum supervision. From time to time, Principal Investigator or Laboratory Research and Operations Manager may provide specific instructions on unusual problems or new project outlines. This position will report to the Principal Investigator or Laboratory Research and Operations Manager.   

Supervision Given
Depending on experience and expertise, the successful applicant may be required to assist in the training and supervision of graduate students/trainees, junior staff, or external collaborators; including providing instruction on the use of lab equipment and procedures, and will help troubleshoot experiments in their area of expertise.

Minimum Qualifications
Completion of a university degree in a relevant discipline or technical program and a minimum four years of related experience or an equivalent combination of education and experience. Some positions may require a graduate degree.

- Willingness to respect diverse perspectives, including perspectives in conflict with one’s own

- Demonstrates a commitment to enhancing one’s own awareness, knowledge, and skills related to equity, diversity, and inclusion

Preferred Qualifications

• An MSc in Biological Sciences (Molecular Biology or other relevant fields) with work experience in single cell genomics biology, next-generation sequencing or molecular biology, preferred
• Working knowledge and understanding of molecular biology and biochemistry techniques such as next-generation sequencing, PCR, DNA/RNA purification and molecular cloning techniques are essential; prior working experience in next-generation sequencing and library construction is considered a great asset.
• Experience with cell culture and aseptic technique.
• Working hands-on experience in tissue handling and tissue dissociation methods would be an asset.
• Ability to perform and troubleshoot a wide variety of molecular and cellular biology techniques including the following: RNA / DNA isolation, quantitative PCR, transfection, flow cytometry, immunohistochemistry, ELISA, protein isolation, and western blotting.
• Preference will be given to applicants with liquid handling robotics, single-cell genomics, next-generation sequencing, and 10x Genomics experience.
• Experience in immunocytochemistry and basic data analysis in R or similar statistics package would be an asset.
• Demonstrated understanding of experimental design and assay optimization.
• Strong interpersonal skills, communication skills (orally and written) and the ability to interact positively and productively with other team members are essential.
• Excellent documentation and organizational skills.
• Able to multi-task, prioritize and handle multi-project assignments concurrently.
• The successful candidate must be well-organized, conscientious, understand the importance of detail, and be able to multi-task and prioritize duties effectively.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: GSCC_F00412_Purchasing_2023_09_18

Job Summary

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Genome Sciences Centre Clerk performs a variety of clerical duties such as assisting with the preparation of reports, maintaining computerized databases, speaking with vendors, reconciling invoices and assisting with the receipt of goods and equipment.

Duties

1. Assists in the preparation of routine laboratory expenditure reports including monthly and annual reports by performing duties such as compiling information from a variety of sources, entering information into financial spreadsheet software such as Excel and producing reports for forwarding to the supervisor.
2. Updates laboratory inventory database by performing duties such as receiving inventory documents, checking for completeness, contacting vendors and entering data into computerized inventory system.
3. Places specific purchase orders with designated external suppliers by performing duties such as contacting suppliers, completing purchase order and arranging for approvals and forwarding to suppliers.
4. Obtains information such as prices and estimated delivery dates for supplies and/or equipment by performing duties such as using the Internet to identify sources and prices of supplies and/or equipment and forwarding information to supervisor.
5. Contacts external suppliers to investigate a variety of matters such as incorrect invoices, pricing problems, outstanding or backordered items and damaged goods; traces duplicate shipments and organizes invoice adjustments and credit notes with suppliers; returns outdated and/or deleted stock to vendors as directed.
6. Maintains a library of supplies and equipment catalogues by performing duties such as using the Internet to identify sources of catalogues, requesting current catalogues from suppliers, and providing information to staff as requested.
7. Reconciles designated accounts by performing duties such as matching information including payments received, refunds and invoices issued and identifying differences. Balances information with ledger. Refers problems to supervisor.
8. Performs a variety of duties related to the receiving of goods and equipment including unpacking, labelling and recording receipt of goods and equipment.
9. Maintains a variety of laboratory supplies and reagents by performing duties such as by performing duties such as reviewing stock on hand against pre-determined re-order points and completing requisitions for approval and forwarding to purchasing.
10. Maintains information such as MSDS sheets, product information and price lists by performing duties such as receiving and requesting information, advising staff of new and/or changed information and filing for future reference.
11. Performs other related duties as assigned.

Qualifications

Education, Training and Experience

• Grade 12 and two year's recent related experience or an equivalent combination of education, training and experience.

Skills and Abilities

• Ability to keyboard at 45 w.p.m.
• Ability to communicate effectively both verbally and in writing.
• Ability to deal with others effectively.
• Physical ability to carry out the duties of the position.
• Ability to supervise
• Ability to operate related equipment.
• Ability to organize work.

Application

As this is a union position, you will also have to apply either as an internal or external applicant through http://www.phsa.ca/careers using the posting reference 152502.

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: GSCC_F00412_Purchasing_2023_09_18 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are onsite positions based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: RA_R00006_Bioinformatics_2023_09_15

Role Summary

The Research Associate will collaborate closely with diverse teams to lead activities focused on the development, application, and validation of novel approaches and workflows within genomic technologies. This dynamic role plays a pivotal part in advancing the field of genomics and contributing to significant projects, including BC Cancer's Personalized OncoGenomics program and the TFRI-led Marathon of Hope Cancer Centres Network. —a major federal initiative co-developed with GSC involvement to accelerate the adoption of cancer precision medicine in Canada, as well as CGEn Technology Development.

Major Responsibilities

• Developing bioinformatics workflows for new projects that require quick turnarounds and/or reproducible results and, where relevant, containerizing them.
• Analyzing sequencing data from technology development experiments in the lab, summarizing results and formally presenting findings in meetings and discussions, including at local, national and international conferences as well as internal meetings.
• Supporting technological advances and providing recommendations to wet and dry lab production groups on new technology and workflow optimizations based on comparative analyses, often with custom bioinformatics tools and workflows.
• Facilitating the transfer of novel analysis pipelines and technologies into production, such as drafting Standard Operating Procedures, training production staff, and assisting with troubleshooting exercises.
• Contributing to grant applications, protocol preparation, and other funding-related documents.
• Performing other related duties as required.

Qualifications
Education and Experience:

• PhD in molecular genetics, molecular biology, genomics, bioinformatics or related field.
• Exploratory data analysis(EDA) involving Illumina and/or ONT data.
• Familiarity with whole genome, transcriptome, capture and epigenetic data.
• Programming experience is a must, preferably with experience in scripting (Python), statistical analysis and data visualisation (eg. R, Matplotlib).
• Familiarity with pipeline tools (eg. Nextflow, singularity) and high-performance computing (slurm) are highly desirable.
• Knowledge and experience with public sequence data repositories (SRA, EGA) are also assets.
• Excellent written and verbal communication skills to effectively convey complex scientific ideas.
• Strong organization skills with the ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
• Ability for critical thinking and independent learning.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RA_R00006_Bioinformatics_2023_09_15 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: RA_R00006_POG_2023_09_14

Summary

The GSC is currently looking for a Research Associate to work on the Personalized OncoGenomics Program (POG). The goal of this program is to develop cutting-edge approaches to aid in the determination of relevant therapeutic options based on the genomic and transcriptomic information derived from a patient’s tumour. Working under the supervision of the Principal Investigator and the Group Leader, the successful incumbent will work with the project team to lead the activities on the development, implementation and performing bioinformatics analysis, as well as interpretation and communication of genomic data in a clinical context.

Duties include:

• Individualized in-depth analysis and interpretation of sequencing data from patient tumour whole genome and transcriptome analysis (WGTA) to evaluate cancer-associated pathways and identify potential clinically actionable targets.
• Communication of genomic findings to clinical teams in the form of written reports and oral presentations.
• Providing scientific direction, leading data analysis and preparation of manuscripts and/or presentation of research papers.
• Performing literature review and identifying, collecting and analyzing internal and external datasets.
• Testing and making use of software for inclusion into research projects.
• Assisting in the preparation of grants, protocols and other funding related documents.

Skills and Abilities:

• PhD in molecular genetics, molecular biology, genomics, bioinformatics or related field.
• Master’s degree in bioinformatics, human molecular genetics, genomics, oncology may be considered.
• Broad understanding of human molecular genetics and cancer biology.
• Experience working with human genomic data, specifically next generation sequencing data (WGS, RNAseq).
• Experience with a common programming languages (eg. Python or R).
• Excellent oral and written communication.
• Organization skills with the ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
• Ability for critical thinking and independent learning.'Ability to work in-person in the office located in Vancouver, BC, Canada.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RA_R00006_POG_2023_09_14 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Staff - Non Union

 

Job Category

Non Union Technicians and Research Assistants

Job Profile

Non Union Salaried - Research Assistant /Technician 3

 

Job Title

Research Assistant/Tech 3 - Aparicio

 

Department

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine

 

Compensation Range

$3,982.67 - $4,703.83 CAD Monthly

 

Posting End Date

September 25, 2023

Note: Applications will be accepted until 11:59 PM on the day prior to the Posting End Date above.

Job End Date

Oct 24, 2024

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

The anticipated start date for this position is October 23 , 2023. The term is for one year with the possibility of extension.

In your application please include (1) a cover letter, and (2) a CV or resume.
 

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career. 

Job Summary

The Aparicio lab is developing new single-cell genome and transcriptome methods for tracking clonal trajectories at the single-cell level in patient tissues and to gain a better understanding of the tumour microenvironment. Our researchers use the latest single-cell genomics technologies to rapidly identify genes that are involved in the development of cancer. This position will be working on the Single-Cell Genomics Platform on research projects currently ongoing in the lab. We are seeking a highly-motivated, detailed, organized, and driven individual with an interest or experience in molecular biology, single-cell genomics, liquid handling robotics, and/or next-generation sequencing.

This entry-level position will provide candidates with an opportunity to work and learn within an academic research environment where continual training and learning are greatly encouraged. The core focus of this position will be providing technical assistance/support on molecular biology, tissue culture, next-generation library preparation and the operations of highly sensitive liquid handling robotics to support current internal/external researchers using the single-cell genomics platform. Hands-on training will be provided to the successful candidate.

This position will provide the candidate with a high level of exposure to single-cell genomics and translational research, as well as, providing opportunities to work collaboratively with industry partners and other researchers globally; the position start date is flexible.

Organizational Status
Aparicio Lab is located in the department of Molecular Oncology at BC Cancer Research Institute in Vancouver, British Columbia, Canada. The successful applicant will report to the Principal Investigator or his/her delegate.

Work Performed

• Plans and performs experiments utilizing established SOPs for investigating single-cell genomics, involving the use of liquid handling robotics and 10x genomics platforms

• Visualize and analyze cells using microscopy and flow cytometry.

• Generation, preparation and submission of next-generation sequencing libraries.

• Using an LMIS system to track and record sample data

• Assist and provide support in molecular biology, tissue culture and next-generation sequencing to other senior searchers

• Assist in developing and implementing standard operating protocols (SOPs).

• Maintains laboratory records and experimental data.

• Assist in general lab maintenance such as reagent preparation, receiving and inventory of lab supplies.

• Present experimental data at internal scientific project meetings.

• Carries out any other related duties as assigned or required in keeping with the qualifications and requirements of this technician level.

Consequence of Error/Judgement
The work is complex and required a high level of training, tasks are assigned and the incumbent exercises a considerable amount of responsibility, initiative and judgment in determining their work schedule to achieve those tasks. Errors may result in the permanent loss of irreplaceable tissue samples, loss of thousands of dollars of material and/or damage to equipment.  Incorrect decisions or actions may damage the reputation of the laboratory, lead to a loss of credibility in this field, and be financially costly. Noncompliance with biosafety and chemical safety regulations may also result in the closure of the facility or loss of grant funding.

Supervision Received
The successful applicant will work under general supervision; receives detailed instructions on the assignment of new duties and thereafter only on new or unusual problems. From time to time, Principal Investigator or Laboratory Research and Operations Manager may provide specific instructions on unusual problems or new project outlines. This position will report to the Principal Investigator or Laboratory Research and Operations Manager.  

Supervision Given
Depending on experience and expertise, the successful applicant may be required to assist in the training and supervision of graduate students/trainees, junior staff, or external collaborators; including providing instruction on the use of lab equipment and procedures, and will help troubleshoot experiments in their area of expertise.

Minimum Qualifications
Completion of a relevant technical program or a university degree in a relevant discipline and a minimum three years of related experience or an equivalent combination of education and experience.

- Willingness to respect diverse perspectives, including perspectives in conflict with one’s own

- Demonstrates a commitment to enhancing one’s own awareness, knowledge, and skills related to equity, diversity, and inclusion

Preferred Qualifications

• A BSc or MSc in Biological Sciences (Molecular Biology or other relevant fields) with work experiences in single-cell genomics biology, next-generation sequencing or molecular biology, preferred

• Working knowledge and understanding of molecular biology techniques such as next-generation sequencing, PCR, DNA/RNA purification and molecular cloning; prior working experience in next-generation sequencing and library construction is considered a great asset.

• Experience with cell culture and aseptic technique.

• Working hands-on experience in tissue handling and tissue dissociation methods would be an asset.

• Preference will be given to applicants with liquid handling robotics, single-cell genomics, next-generation sequencing, and 10x Genomics experience.

• Experience in immunocytochemistry and basic data analysis in R or similar statistics package would be an asset.

• Demonstrated understanding of experimental design and assay optimization.

• Strong interpersonal skills, communication skills (orally and written) and the ability to interact positively and productively with other team members are essential.

• Excellent documentation and organizational skills.

• Able to multi-task, prioritize and handle multi-project assignments concurrently.

• The successful candidate must be well-organized, conscientious, understand the importance of detail, and be able to multi-task and prioritize duties effectively.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No. RP_R00008_VarDB_2023_08_25

Summary

The Software Developer to join the bioinformatics databases team at the Genome Sciences Centre (GSC) will work on developing databases and applications at the GSC, including the Hadoop-based VarDB, graphDB knowledgebase, and clinical databases. Strong Python and node.js server side application skills are required. The role is ideally suited for a creative individual with a strong interest in software development and testing, database development, and automation within a high throughput academic setting. General understanding of clinical or biological data would be an asset.

Duties/Accountabilities:

• Design, plan, and implement web applications and databases
• Work with other project team members to develop and test code, and implement software
• Evaluate third-party software and incorporate new systems into legacy systems
• Produce thorough but concise written documentation of algorithms, validations, SOPs, and other processes and procedures as required.

Qualifications:

• Graduation from a recognized Bachelor of Science Program in Computer Science. A Master’s degree in a relevant field would be a strong asset.
• Two (2) years of recent related experience or an equivalent combination of education, training and experience acceptable to the project lead.

Skills and Abilities:

• Functional knowledge of distributed version control systems, such as SVN or GIT
• Expertise with Python 3.X and able to provide links to code samples via github or other open repository
• Express.js, Node.js and React.js programming
• Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools
• Familiarity with Agile software practices
• Familiarity with the development, testing, and maintenance of relational databases
• Experience with software testing
• Able to collaborate and write software in a team environment
• General biological scientific background or experience would be an asset
• Able to write in concise but precise prose
• Excellent verbal and written communication skills
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment
• Demonstrated ability to efficiently organize work assignments and establish priorities

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No. RP_R00008_VarDB_2023_08_25 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.  RA_R00006_Library Tech D_2023_08_24

Summary

The Research Associate will work within the Technology Development Group (Molecular Biology) under the direction of the Group Leader. Responsibilities include the evaluation of leading technologies that emerge in the marketplace, and the development of novel genomic technologies, such as those that support large-scale provincial and national projects, including BC Cancer’s Personalized OncoGenomics program, and the TFRI-led Marathon of Hope Cancer Centres Network—a major federal initiative co-developed with GSC involvement to accelerate the adoption of cancer precision medicine in Canada, as well as CGEn Technology Development. Tasks include assistance in testing, devising, developing and implementing omic technologies in the laboratory, as well as analyzing, proposing and presenting innovative workflows to increase the efficiency of genomics activities.

Responsibilities

• Test and/or develop novel and efficient methods to enable the scale and throughput the GSC requires to operate at the leading edge of its fields.
• Perform pilot or “custom” experiments, which may require e.g. following protocols published in the literature, or modifying an existing production protocol to meet specific project needs.
• Provide support to production groups, such as drafting Standard Operating Procedures, training production staff, and troubleshooting exercises.
• Summarize and analyze data and results, and formally present findings in meetings and discussions, including at local, national and international meetings. Interact closely and in support of group leaders and their teams to address priorities and project timelines 
• Co-author scientific manuscripts related to research and technology findings.
• Co-develop research grant applications.
• Contribute to quarterly and annual reports for research projects.
• Perform other related duties as required.

Qualifications

Education and Experience:

• PhD in a life sciences-related discipline, or MSc with 3 years demonstrated experience in genomics, or molecular biology. Knowledge or experience in e.g. high-throughput, large-scale DNA sequencing and genomic library production would be a plus.

Skills and Abilities:

• Molecular Biology.
• Knowledge and experience in laboratory automation.
• Knowledge of science and technologies pertaining to cancer genomics.
• Knowledge and experience in operating a laboratory information management system (LIMS) is advantageous.
• Experience with formal quality assurance systems is advantageous.
• Experience with high-throughput sequencing is desirable.

Experience in a supervisory role is an asset.  

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: RA_R00006_Library Tech D_2023_08_24 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.  ABC_P00183_JR# 150051_CCGI_2023_08_08

Summary

Canada’s Michael Smith Genome Sciences Centre (GSC) of the BC Cancer Research Institute is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility in one of the most beautiful, diverse and eclectic cities in the world.

As an Assistant Bioinformatics Coordinator in the Clinical Panels Informatics team at the GSC, you will be responsible for supervising, coordinating and supporting activities related to clinical panel informatics through process monitoring, auditing and reporting as well as development, testing and validation of new clinical bioinformatics processes. The Assistant Bioinformatics Coordinator will report to the Bioinformatics Coordinator and is anchored within a team of exceptional computational scientists and programmers, who collaborate directly on the development and maintenance of robust, cost efficient, and competitive clinical genomics pipelines. By working within the GSCs bioinformatics facility, you will collaborate with clinical and research computational biologists and programmers across bioinformatics groups, clinical lab staff and the quality assurance group to deliver clinical diagnostic genomic testing for patients in BC.

Duties and Responsibilities:

1. Assists the Bioinformatics Coordinator in the day to day activities of the Bioinformatics group by performing duties such as providing input on quantity and quality of work, making recommendations for improvements, workflow and procedures.
2. Coordinates projects of the Bioinformatics group by performing duties such as chairing project-specific meetings and provides project status reports to the Bioinformatics Coordinator, with suggestions towards any required improvement of project management, task allocation and overall process.
3. Develops and implements assays to monitor project progress and measure project accomplishments to ensure that appropriate project focus is maintained and to provide feedback to staff.
4. Provides supervisory support to the Bioinformatics group by performing duties such as:

         a.   Orientating new staff.

         b.   Providing input to the Bioinformatics Coordinator on training requirements.

         c.   Providing input to the Bioinformatics Coordinator on the establishment of clear definitions of responsibility for employees.

         d.   Assigning workload assignments and establishing work schedules.

         e.   Reviewing and establishing work priorities and adjusting work schedules to ensure clinical priorities are met.

         f.    Completing performance reviews and addressing performance issues in conjunction with the Bioinformatics Coordinator.

5.         Participates in the recruitment of staff through methods such as interviewing internal and external applicants and forwards hiring recommendations.

6.         Participates in the implementation of quality improvement programs to ensure clinical assays are provided in the most efficient and effective way by performing duties such as:

         a.         Monitoring quality and quantity of service and information provided by the bioinformatics group and identifying areas for change and/or improvement.

         b.         Generating quality metrics and reports to evaluate quality and robustness of clinical bioinformatic pipelines

         c.      Develops clear and concise documentation

7.         Assesses practical needs for identified clinical priorities for GSC in conjunction with the Bioinformatics Coordinator and Analysis Group Leader.

8.         Participates in a variety of meetings by performing duties such as providing and/or receiving information and contributing to decision making.

9.         Participates, in conjunction with the Bioinformatics Coordinator, in determining the computer infrastructure necessary for successful completion of projects and ensured viability of research programs by performing duties such as providing input and recommendations regarding purchasing decisions related to hardware, software and related items for the clinical bioinformatics platform.

10.       Interprets statistical analyses and makes recommendations for review including preparing reports on statistical findings for publication and presentation both internally and externally of the GSC.

11.       Generates specification for pipeline improvements/implementations such as determining user requirements, examining and identifying problems with existing systems and recommending modifications to and/or new systems; provides details of cost benefit analysis

12.       Performs technical functions related to the bioinformatic functions of the GSC.

13.       Performs other related duties as required.

Qualifications

Education, Training and Experience

• Graduation from a recognized Bachelor’s program in a related discipline such as Biochemistry, Genetics, Computer Science.  A minimum of four (4) years of recent related experience in a research and or clinical laboratory including experience in computer programming and quantitative data analysis, handling next generation sequencing data, database development and data storage schemas or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

• Comfortable working in a Linux environment, including experience with shell scripting and common command-line tools.
• Proven expertise with Python, R, and/or other similar high-level languages
• Functional knowledge of distributed version control systems, such as Git.
• Demonstrated experience with analysis of next generation sequencing data with an understanding of standards and guidelines for validating clinical bioinformatics analysis pipelines using these technologies.
• Demonstrated ability to accept responsibility and work independently.
• Demonstrated ability to work effectively with others in a team environment.
• Demonstrated ability to supervise staff and to efficiently organize work assignments and establish priorities to meet set milestones.
• Excellent organizational, leadership interpersonal and communication skills.
• Demonstrated ability to write technical documents including validations and procedure manuals.
• Experience with bioinformatics workflow managers and database development would be considered an asset.
• Physical ability to perform the duties of the job.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using ABC_P00183_JR# 150051_CCGI_2023_08_08 in the subject line of your email.

As this is a union position, you will also have to apply either as an internal or external applicant through http://www.phsa.ca/careers using the posting reference 150051.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

What you’ll do

• In collaboration with the Principal Investigator(s) (PIs), coordinate the preparation and submission of grant proposals.
• Interact with both national and international universities and granting agencies. Ensure flow of information with internal and external stakeholders regarding grant related matters and make arrangements for visiting speakers and guests.
• Coordinate registration and travel arrangements for staff attendance at seminars and meetings. This includes completing registration (on-line or phone), abstract submission, making travel and lodging reservations, culminating expense reimbursements to the attendee and/or cost recovery from the conference organizers.
• Human resource responsibilities include recruitment of staff by posting/advertising internally and externally (UBC), coordinating interviews and screening applications for review by hiring supervisors. Manage new hire orientation process and ensure all safety and personnel documentation is in place according to policies, guidelines and legislations.
• Ensure all hiring, appointment and payroll processes are complete for employees. Liaise with various PHSA units such as Payroll and Human Resources and in some cases, UBC, to ensure a seamless process and minimize errors.
• Act as the main contact for ordering lab and office supplies for the department. Manage and process various requisitions such as travel, expense reimbursements, cheque requests, and honorariums for the Department Head and PIs. 

 

What you bring

• A level of education, training, and experience equivalent to a Diploma in a relevant area such as business administration or finance from a recognized college.
• Three (3) years’ recent, related experience a research environment and in project management.
• Strong interpersonal and communication skills and the ability to demonstrate good judgment, tact and discretion.
• Demonstrated time management skills and the ability to assist others in meeting deadlines.
• Demonstrated ability to make sound decisions and resolve administrative issues/problems.
• Detail orientation and the ability to complete accurate work in a timely matter.
• Knowledge of and experience with grant applications. Knowledge and experience in budget preparation, tracking expenditures and identifying sources of variance.
• Commitment to upholding the shared responsibility of creating lasting and meaningful reconciliation in Canada as per TRC (2015) and BC's Declaration on the Rights of Indigenous Peoples Act (2019).
• Knowledge of social, economic, political and historical realities impacting indigenous communities and familiarity with Indigenous Cultural Safety and anti-racism and accompanying reports (BC DRIPA, TRC, etc.).

What we bring

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• Enjoy a comprehensive benefits package, including municipal pension plan, and psychological health & safety programs and holistic wellness resources.
• Annual statutory holidays (13) with generous vacation entitlement and accruement.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: Regular, Full-Time

Salary Range: $51,156 - $68,455 per year. The starting salary for this position would be determined with consideration of the successful candidate’s relevant education and experience, and would be in alignment with the provincial compensation reference plan. Salary will be prorated accordingly for part time roles.

Location: 675 W 10th Ave, Vancouver, BC V5Z 1G1 / This position can be hybrid.

Applications will be accepted until position is filled.

Hours of Work: Monday to Friday; 0830-1630

Requisition # 148648

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

 

What we do

BC Cancer provides comprehensive cancer control for the people of British Columbia. BC Cancer is part of the Provincial Health Services Authority (PHSA).

(PHSA) plans, manages and evaluates specialized health services with the BC health authorities to provide equitable and cost-effective health care for people throughout the province. Our values reflect our commitment to excellence and include: Respect people – Be compassionate – Dare to innovate – Cultivate partnerships – Serve with purpose.

Learn more about PHSA and our programs: jobs.phsa.ca/programs-and-services

PHSA and BC Cancer are committed to employment equity, encouraging all qualified individuals to apply. We recognize that our ability to provide the best care for our diverse patient populations relies on a rich diversity of skills, knowledge, background and experience, and value a safe, inclusive and welcoming environment.

Reconciliation is an ongoing process and a shared responsibility for all of us. The BC Governments’ unanimous passage of the Declaration on the Rights of Indigenous Peoples Act was a significant step forward in this journey—one that all health authorities are expected to support as we work in cooperation with Indigenous Peoples to establish a clear and sustainable path to lasting reconciliation. True reconciliation will take time and ongoing commitment to work with Indigenous Peoples as they move toward self-determination. Guiding these efforts Crown agencies must remain focused on creating opportunities that implement the Truth and Reconciliation Commission Mandate.

What you’ll do

• In collaboration with the Principal Investigator(s) (PIs), coordinate the preparation and submission of grant proposals.
• Interact with both national and international universities and granting agencies. Ensure flow of information with internal and external stakeholders regarding grant related matters and make arrangements for visiting speakers and guests.
• Coordinate registration and travel arrangements for staff attendance at seminars and meetings. This includes completing registration (on-line or phone), abstract submission, making travel and lodging reservations, culminating expense reimbursements to the attendee and/or cost recovery from the conference organizers.
• Human resource responsibilities include recruitment of staff by posting/advertising internally and externally (UBC), coordinating interviews and screening applications for review by hiring supervisors. Manage new hire orientation process and ensure all safety and personnel documentation is in place according to policies, guidelines and legislations.
• Ensure all hiring, appointment and payroll processes are complete for employees. Liaise with various PHSA units such as Payroll and Human Resources and in some cases, UBC, to ensure a seamless process and minimize errors.
• Act as the main contact for ordering lab and office supplies for the department. Manage and process various requisitions such as travel, expense reimbursements, cheque requests, and honorariums for the Department Head and PIs. 

 

What you bring

• A level of education, training, and experience equivalent to a Diploma in a relevant area such as business administration or finance from a recognized college.
• Three (3) years’ recent, related experience a research environment and in project management.
• Strong interpersonal and communication skills and the ability to demonstrate good judgment, tact and discretion.
• Demonstrated time management skills and the ability to assist others in meeting deadlines.
• Demonstrated ability to make sound decisions and resolve administrative issues/problems.
• Detail orientation and the ability to complete accurate work in a timely matter.
• Knowledge of and experience with grant applications. Knowledge and experience in budget preparation, tracking expenditures and identifying sources of variance.
• Commitment to upholding the shared responsibility of creating lasting and meaningful reconciliation in Canada as per TRC (2015) and BC's Declaration on the Rights of Indigenous Peoples Act (2019).
• Knowledge of social, economic, political and historical realities impacting indigenous communities and familiarity with Indigenous Cultural Safety and anti-racism and accompanying reports (BC DRIPA, TRC, etc.).

What we bring

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• Enjoy a comprehensive benefits package, including municipal pension plan, and psychological health & safety programs and holistic wellness resources.
• Annual statutory holidays (13) with generous vacation entitlement and accruement.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: Casual

Salary Range: $51,156 - $68,455 per year. The starting salary for this position would be determined with consideration of the successful candidate’s relevant education and experience, and would be in alignment with the provincial compensation reference plan. Salary will be prorated accordingly for part time roles.

Location: 675 W 10th Ave, Vancouver, BC V5Z 1G1

Applications will be accepted until position is filled.

Hours of Work: Monday to Friday; 0830-1630

Requisition # 147998

Job Category

Non Union Technicians and Research Assistants

Job Profile

Non Union Salaried - Research Assistant /Technician 3

 

Job Title

Research Assistant/Tech 3 - Sorensen

 

Department

Sorensen Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine

 

Compensation Range

$3,982.67 - $4,703.83 CAD Monthly

 

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

The anticipated start date for this position is July 4, 2023. The term is for one year with the possibility of extension.

In your application please include (1) a cover letter, and (2) a CV or resume.

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career. 

Job Summary

The basic and translational research performed in the Sorensen laboratory seeks to improve basic knowledge and treatment options in Ewing sarcoma and other high-risk pediatric cancers. This position will mainly work on the characterization of pathways facilitating adaptation of pediatric cancer cells to stress and promoting metastasis.

The Research Assistant (RA) will be responsible, under supervision, for laboratory work including biochemical, molecular, and cell-based analyses, and in vivo mouse procedures.

Organizational Status
The Sorensen Lab is located at the BC Cancer Research Centre. The RA reports directly to the Primary Investigator and different study leads within the research group. The position requires to use a high degree of initiative, tact and professional judgement in carrying out responsibilities related to the research. The incumbent will also be required to report to the primary investigator and study leads in a clear and timely manner.

Work Performed

Laboratory Research Duties:

• The incumbent will be responsible for laboratory duties which include, but not limited to, western blotting, immunoprecipitation, PCR and RT-PCR, plasmid preparation, bacterial culture, general buffer preparation, and mammalian/cancer cell culture, mammalian transfection/lentiviral transduction, immunofluorescent staining, microscopy, and cellular/molecular biology (cell proliferation, death, cytotoxicity, etc.), preparing samples for proteomics (e.g. mass spectrometry). Training for additional research techniques will be provided as needed.
• In addition to general laboratory duties, the incumbent will divide their bench time among several concurrent projects, thus efficient time management of bench work to various projects will be an asset.

Animal Research Duties:

• Maintains current knowledge of, and ensures compliance with, animal care regulations. As part of this, the incumbent will acquire animal research center handling and certification of techniques and procedures as it relates to required mouse work.
• Maintains daily care of laboratory mice including, primary tumour caliper measurements, and logging changes in animal health and general health conditions. The incumbent will also keep an up-to-date record of mice and mouse cages using Mosaic software.
• Performs mouse surgeries and techniques including blood collection, tumour implantation, injection of tumor cells (subcutaneous and tail-vein injections), saline/vehicle solutions, and investigational anti-cancer drugs. The incumbent will be also responsible for small animal bioluminescence (IVIS) imaging of mouse tumours, and other organs, as well as harvesting of mouse tissues.
• The incumbent will also perform ancillary laboratory techniques such as media/drug preparation, cell culture, instrument sterilizations, polymerase chain reaction analysis (for genotyping), and receiving and processing laboratory animal care supplies.

Consequence of Error/Judgement
When dealing with laboratory chemicals, the incumbent will exercise judgement based on the Biosafety and Laboratory Safety provided by online training modules. The incumbent is expected to exercise good judgment at all times and if in doubt seek advice from those that she/he may report to.

Supervision Received
The Research Assistant will work mostly independently from day to day. The Research Assistant will be supervised by the Principal Investigator with additional guidance provided by the study leads, and will be expected to report his/her results to them regularly.

Supervision Given
The Research Assistant is not required to directly supervise anyone. She/he may be required to allow a student or new staff member to shadow them, or serve as a resource for undergraduate students.

Minimum Qualifications
Completion of a relevant technical program or a university degree in a relevant discipline and a minimum three years of related experience or an equivalent combination of education and experience.

- Willingness to respect diverse perspectives, including perspectives in conflict with one’s own

- Demonstrates a commitment to enhancing one’s own awareness, knowledge, and skills related to equity, diversity, and inclusion

Preferred Qualifications

• Undergraduate degree in a Medical/Health Science discipline preferred.
• Experience in laboratory bench work from the same or similar research field would be a key asset.
• Knowledge of scientific terminology and familiarity with research study protocols, ethics approval processes, and previous experience with mouse models and proteomics techniques are also an asset.
• Ability to work independently and collaboratively.
• Excellent communication skills are required, including effective inter-personal, oral and listening skills.
• Attention to details.
• Good organizational skills are essential to plan experiments efficiently, track progress and provide clear and timely updates to study team members.

Three graduate student positions are available at the Department of Molecular Oncology, BC Cancer Research Institute for the development of novel radiopharmaceuticals for detection and radioligand therapy of cancer. The graduate student candidates will register through the Interdisciplinary Oncology Program (www.iop.ca), University of British Columbia, and pursue either an MSc or PhD degree.

The student candidates will conduct research on the design and synthesis of imaging probes and radiotherapeutic agents targeting biomarkers overexpressed in cancers. Research activities will involve the production and isolation of radioisotopes, peptide and multi-step organic synthesis, and radiolabeling small molecules/peptides/antibodies for PET/CT and SPECT/CT imaging, biodistribution, and radioligand therapy studies in various animal models.

Qualified candidates should have a bachelor degree preferably in chemistry, biology or pharmacy with interest in the development of cancer-targeted radiopharmaceuticals. The ability to conduct research in a collaborative environment is required including good oral and written communication skills in English. For more information regarding application for the Interdisciplinary Oncology Program at the University of British Columbia, please check the following website: www.iop.ca

Before applying, interested student candidates should first contact:

Dr. Kuo-Shyan Lin

Senior Scientist, BC Cancer Research Institute

Associate Professor, University of British Columbia

E-mail: klin@bccrc.ca

Job Category:

Faculty Non Bargaining

Job Title:

Research Associate - Bioinformatics

Department:

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine (Samuel Aparicio)

 

Job Summary:

The Aparicio lab is seeking a Bioinformatics Research Associate to join our dynamic and accomplished team, renowned for its contributions to breast oncology research. Our lab's success stems from a combination of technical excellence, hard work, and a global network of outstanding collaborators from Canada, the United States, and the United Kingdom, all working together to advance our understanding of the evolution of breast, ovarian, and other cancers.

As part of the University of British Columbia and the BC Cancer Research Centre, the Aparicio lab benefits from the abundant biomedical resources available at these institutions. These resources have enabled our team to develop expertise in techniques ranging from CRISPR gene editing to spatial imaging and single molecule sequencing. As a result, our trainees have had the opportunity to share their work in esteemed journals like Nature, Nature Cancer, and Cell in recent years.

In this role, the Bioinformatics Research Associate will primarily focus on leading and participating in projects that investigating functional genomics using sequencing and expression data for breast oncology and cancer evolution.

This position offers a unique opportunity for mentoring trainees, supervising staff, and interacting with industry professionals, providing an ideal platform to develop the essential skills for a successful medical research career in academia or industry. As a Research Associate at the University of British Columbia, you will thrive under the guidance of an exceptional mentor within the supportive environment of the BC Cancer Research Centre.

This position is located within a health-care facility. Therefore, this position requires successful verification of full vaccination against COVID-19 provided prior to the start date, as required by the provincial health mandate.

The UBC Department of Pathology and Laboratory Medicine is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients. The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence.

ORGANIZATIONAL STATUS

The researcher associate will play a leadership role in the Aparicio lab, and will be reporting directly to Dr. Samuel Aparicio who is the primary investigator of the laboratory.

WORK PERFORMED

• Planning and designing of experiments;
• Analyzing, interpreting and compiling data in study reports, presenting results, and participating in the preparation of scientific manuscripts and grant application packages
• Updating Dr. Aparicio and the group on the status of projects during lab meetings, in email correspondence and phone conferences;
• Managing projects with key academic and industry partners.
• Performing regular reviews of the relevant literature;
• Management and supervision of trainees;
• May be involved in recruitment and training of trainees;

CONSEQUENCE OF ERROR

Accountable for the management and progress of research projects.  Errors in judgment may cause severe impact to research progress, reputational good standing and international collaborations.

SUPERVISION RECEIVED

Works independently under direction of PI, Dr. Samuel Aparicio Opportunities to work collaboratively with Industry partners and other researchers at UBC and globally

SUPERVISION GIVEN

Assists and oversees research assistants and students as required.  Assists and provides guidelines to other research members, as required

MINIMUM QUALIFICATIONS

• PhD degree in the computer science, bioinformatics or equivalent
• At least 4 years experience in bioinformatics research
• Expertise in next-generation sequencing genomics and transcriptomics
• Demonstrated success in computational academic research
• Proven ability to multi-task in a deadline oriented environment with minimal supervision
• Excellent organizational skill and ability to learn new skills quickly

PREFERRED QUALIFICATIONS

• Extensive knowledge of cellular and molecular biology, biochemistry and genetics
• Experience with cancer research
• Outstanding oral and written communication, analytical, and interpersonal skills
• Ability to work independently and within a team environment.
• The ability to balance a broad strategic vision with attention to detail
• Candidates should demonstrate the ability to work in a highly interdisciplinary environment.

Become a part of our dedicated team as we continue to break new ground in cancer research and translate our findings into meaningful advancements in patient care. Apply now to contribute your skills and enthusiasm to the Aparicio lab, and help shape the future of oncology research.

MSc/PhD student - Radiopharmaceutical development for high lethality cancers

We are looking for a motivated graduate student to join our team to develop radiopharmaceuticals for high-lethality cancers. The graduate student will have the opportunity to design, synthesize, and radiolabel pharmacophores (e.g., peptides, drug inhibitors, antibodies, antibody mimetics, etc.) to improve the diagnosis and treatment of solid and hematological malignancies. Our research involves the use of human and mouse models, patient-derived samples, and cutting-edge imaging technologies.

The Lau lab is a part of the Department of Integrative Oncology, a world-class interdisciplinary research unit at BC Cancer, and the Faculty of Medicine, UBC. The Lau lab has a strong interest in translational cancer research and experience with first-in-human clinical trials. The graduate student will work with and learn from chemists, radiochemists, molecular biologists, medical physicists, and nuclear medicine physicians. The graduate student is expected to participate in all aspects of project development, planning, and collaboration.

The graduate student will enrol in the Interdisciplinary Oncology Program (IOP; www.iop.ca) at The University of British Columbia (www.grad.ubc.ca). Please note, no applicant will be admitted into the IOP program without a commitment from a research supervisor.

Qualified candidates should have a bachelor's degree preferably in molecular biology, chemistry, biochemistry, or pharmacology. Interested candidates should send a statement of research interest, curriculum vitae, transcripts, and contact details for 3 referees to:

Joseph Lau, PhD

Scientist, Integrative Oncology, BC Cancer

Assistant Professor, Radiology, UBC

Email: jlau[at]bccrc.ca

Three postdoctoral fellow positions are immediately available at the BC Cancer Research Institute in Vancouver, Canada for the development of novel radiopharmaceuticals for cancer imaging and radioligand therapy. The postdoctoral fellows will conduct research in the design and synthesis of radioligands targeting biomarkers overexpressed in cancers. Research activities will involve the production and isolation of radioisotopes, peptide and multi-step organic synthesis, and radiolabeling small molecules, peptides and antibodies with various imaging and radiotherapeutic isotopes (F-18, Ga-68, Zr-89, Tc-99m, I-123, In-111, Lu-177, Ac-225 …).

Qualified candidates should have a PhD degree in radiochemistry, organic or medicinal chemistry with experience in peptide or multi-step organic synthesis. Experience with HPLC, micro-scale reactions, and radiochemistry is strongly desirable but not required. The ability to perform research in a collaborative environment is required including excellent oral and written communication skills. This joint position between BC Cancer Research Institute and University of British Columbia (UBC) is for a period of two years with the possibility of renewal.

Interested candidates should send a letter of application, curriculum vitae, and names of three references to both Dr. Kuo-Shyan Lin (klin@bccrc.ca) and Dr. François Bénard (fbenard@bccrc.ca). Review of applications will begin immediately and will continue until the position is filled.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No. CB_P01067_HSA145548_Bioinfo Database Devt_2023_05_15

Summary

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority, patient safety is a priority and a responsibility shared by everyone at PHSA. As such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Computational Biologist will participate in the analysis of sequencing data by developing, refining and adapting bioinformatics tools for a high-throughput processing pipeline.  The Computational Biologist will also participate in the development and maintenance of the production databases, which provide tracking of all of the laboratory and bioinformatics analysis pipelines at the GSC.  Additionally, the Computational Biologist will assist in the packaging and distribution of developed tools and analysis results to the scientific community, and will be contributing to the preparation of scientific publications. 

Duties

Assists in the development and maintains the core sequence analysis pipelines at GSC, including but not limited to: QC of sequencing data; Alignment of sequenced reads; Formatting and manipulation of alignment files for use by downstream pipelines (e.g. merging, reheadering); Dissemination of data to collaborators; New analyses pipelines as required. Assists in the development and maintains GSC laboratory, quality and analysis databases, including: Routine database integrity checks and database maintenance; Development of views and interfaces for data entry; Development of reports for internal users and collaborators; Investigation of new frameworks and designing new schemas and tables. Communicates with stakeholders in the lab, on analysis teams, and with external collaborators to understand and document requirements for development and to respond to questions about collaborator data and data quality. Works with upstream and lab teams generating data to be housed in the database, and with downstream users of the databases to meet requirements, and responds to internal requests for query and API support. Participates in the development and maintains ETL pipelines between GSC production databases. Manages the storage and compression of over 5Pb of internally generated sequencing data as well as the download and storage of external data. Works closely with GSC Systems team and Quality Assurance team to establish and carry out best practices for data security, and ensure compliance with ISO 27001 certification, CAP/DAP clinical accreditation requirements and other data use agreements. Tests and validates new data analysis software for analyses such as alignment, duplicate marking and merging. Participates in code walk-throughs and reviews of solutions. Participates in the design and builds database solutions, taking performance into consideration. Coordinates production problem resolution for assigned applications, including working with other technical teams. Produces thorough but concise written documentation of database tables, applications, validations, SOPs, and other processes and procedures as required. Performs other related duties as required. Qualifications Education, Training and Experience Graduation from a recognized Bachelor of Science Program in Computer Science or equivalent with significant computer science components.  Two (2) years of recent related experience or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders. Skills and Abilities Demonstrated expertise in database programming and database design. Demonstrated ability in Python. Experience designing and/or maintaining a relational database including knowledge of SQL or PostgreSQL, and with ORMs. Experience with REST API development. Experience with front-end web development (AngularJS, React). Functional knowledge of distributed version control systems, such as GIT. Experience developing software as part of a team, familiarity with Agile development and ticketing systems. Comfortable working in an Unix environment, including experience with shell scripting and common command-line tools. Excellent verbal and written communication skills. Demonstrated interpersonal skills including the ability to work effectively with others in a team environment. Demonstrated ability to efficiently organize work assignments and establish priorities.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No. CB_P01067_HSA145548_Bioinfo Database Devt_2023_05_15 in the subject line of your email. As this is a union position, internal applicants must visit internaljobs.phsa.ca to field their online application.l

This posting will remain online until filled.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: RP_R00008_Karsan Lab_2023_05_03

Summary

The Karsan lab at Canada’s Michael Smith Genome Sciences Centre (GSC) are seeking a Research Programmer to join a Marathon of Hope Cancer Centre research project. The team will be working with other research programmers at the Karsan lab to perform data analysis on next-generation sequencing (NGS) data including but not limited to WGS, RNA-seq, targeted sequencing, scRNA-seq, scATAC-seq, and Bisulfite-Seq, to study of clonal evolution of blood cancers and resistance to therapy. We seek candidates with strong analytical and programming skills to research, develop, and improve existing research pipelines.

The role is ideally suited for detail-oriented individuals with a strong interest in data analysis, research, and scientific programming within a high throughput academic setting.  The Karsan lab has a history of strong publications and can offer great experience in research with full access to the GSC’s world-class compute cluster.  Additionally, the Karsan Lab has a diverse computational biology core for knowledge sharing, collaboration, and support. 

Duties/Accountabilities: 

• Design and implement bioinformatic data analysis to meet objectives of the project
• Work with other project team members to develop and test code, and implement analysis
• Collects, records, analyzes, validates, interprets and organizes experimental and research data and communicates scientific findings to the Principal Investigator.
• Evaluate and incorporate third-party software into pipelines
• Produce thorough but concise written documentation of experiments, algorithms, validations, and other procedures as required.

 Qualifications:

• Graduation from a recognized Bachelor of Science Program in Computer Science or relevant program. A Master’s degree in a relevant field would be a strong asset. 
• Two (2) years of recent related experience or an equivalent combination of education, training, and experience.

Core Skills and Abilities: 

• Expertise with scientific programming and able to provide links to code samples via GitHub
• Familiarity with cancer biology
• Excellent verbal and written communication skills
• Demonstrated ability to interpret results
• Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools
• Established ability to efficiently organize work assignments and establish priorities
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.

Additional Assets:

• Familiarity in statistical analysis using modern computational tools (experience with any relevant tools will be considered, but R and Python are preferred)
• Familiarity in next-generation sequencing datasets

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RP_R00008_Karsan Lab_2023_05_03 in the subject line of your email.

This posting will remain online until filled.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

PHSA and BC Cancer are committed to employment equity, encouraging all qualified individuals to apply. We recognize that our ability to provide the best care for our diverse patient populations relies on a rich diversity of skills, knowledge, background and experience, and value a safe, inclusive and welcoming environment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: SS2_R00010_Clinical Informatics_2023_05_02  

Summary

We are seeking a dynamic and innovative leader to join our team as a leader in clinical bioinformatics and cancer precision genomics. In this role, you will oversee the development and execution of cancer genome analysis with a focus on precision medicine approaches and reporting. You will lead a team of bioinformatic analysts and work closely with other teams at the Genome Sciences Centre to ensure that projects and analyses are executed on time, within budget, and to the highest standards.  The role is part of the Genome Sciences Centre’s precision medicine initiative the “Personalized Oncogenomics Program” (POG) and the Terry Fox Research Institute’s “Marathon of Hope”.

Responsibilities:

• Leadership, support and day-to-day supervision of members of the clinical informatics team
• Lead and manage a team of researchers in the design, execution, and analysis of cancer precision genomics analysis and reporting.
• Develop and implement strategies to optimize and improve cancer genomics research approaches and methodologies.
• Collaborate with leadership teams from cancer genomic studies, including the Personalized OncoGenomics Program (POG) and Precision Oncology For Young People (PROFYLE), to deliver genomics information in the area of precision oncology. This will include:
  • Delivery of whole genome and transcriptome integrative analysis genomic reports to multi-disciplinary clinical teams
  • Collaboration with stakeholders and research groups to deliver novel technologies in the context of precision oncology studies
  • Providing leadership and expertise to support program-wide decision-making and strategic planning
  • Collaborate with stakeholders to provide leadership and technical expertise for scientific publications and grant writing
• Engage with national and international collaborative genomics initiatives including large-scale genomics projects and investigator initiated clinical trials. This will include:
  • Participation in the development of clinical trial design
  • Collaborate with members of external organizations for the development of distributable software
  • Establishment and implementation of data and software sharing approaches
• Conduct bioinformatic analyses and interpretation of genomic data
• Collaborate with bioinformatics teams across the organization to help develop and improve production bioinformatics pipelines and genomics reporting in a clinical research setting.
• Collaborate with teams at the Genome Sciences Centre including those representing bioinformatics, computational biology, and data science to ensure the delivery of high-quality reports and results.
• Engage with external collaborators to identify new opportunities and foster relationships to support ongoing research efforts.
• Participate in the preparation and submission of grant proposals to fund cancer genomics research initiatives.
• Retain familiarity with the latest advances in cancer genomics research and emerging technologies and apply this knowledge to inform new research and development strategies.

Qualifications:

• PhD in Genetics, Genomics, Cancer Biology, or related field.
• 5+ years of experience in cancer genomics research, with a focus on precision medicine.
• Demonstration of leadership and management skills, with experience leading cross-functional teams.
• Familiarity with genomic data analysis approaches and data interpretation.
• Excellent communication and interpersonal skills, with the ability to work collaboratively with internal and external stakeholders.
• A strong publication record in the field of genomics.

Required skills:

• Highly collaborative and team-oriented approach is required.
• Effective oral and written communication skills
• In-depth knowledge and extensive research experience in the field of cancer biology and cancer genomics
• Proficiency in one or more common programming and/or scripting language
• Ability to manage time and engagement across diverse tasks and projects effectively while meeting expected deliverables in the allocated time-frame

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using SS2_R00010_Clinical Informatics_2023_05_02  in the subject line of your email.

This posting will remain online until filled.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

PHSA and BC Cancer are committed to employment equity, encouraging all qualified individuals to apply. We recognize that our ability to provide the best care for our diverse patient populations relies on a rich diversity of skills, knowledge, background and experience, and value a safe, inclusive and welcoming environment.

Research Assistant 3

Role Summary

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position. Entry to this advanced working level is restricted to those who are thoroughly conversant with all of the complexities of the specific research programs and methodologies of the hiring laboratory.  They are expected to exercise initiative and independent judgment in the performance of duties such as staff supervision and scheduling of work, administrative support, and collaboration on research papers.  They are designated the responsibility of ensuring that the day to day work meets the research objectives.

Key Accountabilities

Under limited supervision, performs complex technical procedures and experiments by following established laboratory procedures according to written protocols. Provides input regarding modification of procedures as requested by Department Head, Principal Investigator, or designate. Maintains and stores cell lines and primary cultures. Maintains and stores test materials and products. Maintains inventory of laboratory supplies and equipment. Demonstrated work methods or procedures to less experienced assistants as designated; orients new staff to department. Provides day to day scheduling and supervision of assigned work. Provides significant contributions to the preparation and/or presentation of research papers. Assists the Department Head or Principal Investigator in preparing grant applications and budgets.

Qualifications

A level of education, training, and experience equivalent to graduation from a recognized Bachelor’s program in an appropriate discipline (e.g. Bachelor of Science); plus five (5) years of recent related experience in a research laboratory.

This position requires strong skills in the areas of molecular biology, protein biochemistry and cell biology, including, but not limited to, mammalian cell culture, cloning, RNA and DNA purification, lentiviral transduction, PCR Western blotting, microscopy and imaging. Working knowledge and performance of aseptic technique is essential. Expertise in the use and handling of hazardous materials such as biological agents, radioactive substances and/or cytotoxic drugs is preferred. The successful candidate must be well-organized, conscientious, understand the importance of detail in observing and recording data, and be able to multi-task and prioritize duties effectively. Experience working with pre-clinical animal models, especially mice, is a valuable asset.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.  CSA_F00420_HEU144261_Systems_2023_04_17

Summary

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

Provides computer technical support services at the Genome Sequence Centre (GSC).  Duties include investigating and resolving hardware and software problems, installing, configuring and testing hardware and software, providing training to users and participating in GSC bioinformatic projects.

Duties

1. Maintains the computer system and network for the GSC by performing duties such as responding to system, communications and user problems, investigating problems and taking corrective action as per established procedures. Resolves user issues on the technical infrastructure. Refers problems as required Installs, configures, modifies and tests all computer hardware within the GSC network.
2. Installs, configures and upgrades server software as directed.
3. Installs and provides technical support for GSC operating systems and including UNIX-based scientific applications such as Apache, AceDB, CONSED, MySQL, Perl Modules, and other bioinformatic software.
4. Provides training to users in the use of hardware and software and prepares instructional material.
5. Works with others in the implementation of the GSC network infrastructure (servers, network, workstations, website) by installing network components and testing.
6. Installs, configures, modifies and tests all computer hardware within the GSC network.
7. Maintains printers, barcode readers and associated hardware.
8. Modifies website content as required.  Maintains hardware and runs web server software.
9. Carries out and monitors GSC wide backup and recovery procedures.
10. Provides input into the development of the GSC’s information technology infrastructure strategy which includes data, voice and video technology.
11. Under direction, monitors and maintains security profiles for computer systems by adding and deleting user names and reviewing security logs.
12. Codes, modifies, tests and maintains programs from specifications to complement systems implementation and meet technical and client support requirements.
13. Maintains an inventory of software and their version for all computers within the GSC network.
14. Writes basic computer programs to automate frequently performed tasks.
15. Performing other related duties as required.

Qualifications

Education, Training and Experience

• Completion of Grade 12 plus graduation from a recognized two (2) year systems technology diploma, plus two (2) years of recent related experience or an equivalent combination of education, training and experience.

Skills and Abilities

• Ability to type.
• Ability to communicate and deal effectively both verbally and in writing.
• Ability to work with other effectively.
• Physical ability to carry out the duties of the position.
• Ability to organize work.
• Ability to operate related equipment.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: CSA_F00420_HEU144261_Systems_2023_04_17 in the subject line of your email.

ATTN: PHSA Employees:

To be considered as a PHSA employee (internal applicant) for this position, you must apply online via your internal profile at http://internaljobs.phsa.ca   

This posting will remain online until filled.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

PHSA and BC Cancer are committed to employment equity, encouraging all qualified individuals to apply. We recognize that our ability to provide the best care for our diverse patient populations relies on a rich diversity of skills, knowledge, background and experience, and value a safe, inclusive and welcoming environment.