Dr. Pierre Lane is a Principal Investigator at the BC Cancer. He has formal training in Engineering Physics and holds academic appointments at Simon Fraser University (SFU) and the University of British Columbia (UBC). He is interested in the in vivo application of optical imaging, tissue optics, and spectroscopy for the early detection, diagnosis, and management of cancer. He develops and evaluates new optical tools to address unmet clinical needs and works closely with clinical collaborators to evaluate and test these tools in a clinical context. These tools include instrumentation, software, computer algorithms, systems and devices that can be used clinically or in a laboratory to measure the structural, morphological, functional, biochemical or molecular characteristics of tissue. Active projects involve the application of optical coherence tomography, confocal microscopy, and autofluorescence imaging to the lung, oral cavity and cervix.


Simon Fraser University


Current Appointments

Associate Professor, Engineering Science (Biomedical Engineering), SFU

Affiliate Associate Professor, School of Biomedical Engineering, UBC


B.Eng and Mgmt, Engineering Physics, McMaster University (Hamilton, ON), 1993

M.Eng, Electrical Engineering, Technical University of Nova Scotia (Halifax, NS), 1996

Ph.D, Electrical and Computer Engineering, Dalhousie University (Halifax, NS), 1999


Dual modality OCT-AFI

Both optical coherence tomography (OCT) and autofluorescence imaging (AFI) have shown potential for cancer detection. OCT is able to measure epithelial thickness and identify micro invasion through the basement membrane. AFI in the lung and oral cavity is used clinically to identify abnormal tissue and guide biopsy site selection. Recently, we demonstrated the ability of catheter-based AFI to identify vascular networks in small peripheral airways.

Selected Publications

Back to top