Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No. CB_P01066_Software Development_HSA154623_2023_10_24

Job Summary

In accordance with the Mission, Vision and Values, and strategic directions of PHSA, safety, including both patient and employee safety, is a priority and a responsibility shared by everyone at PHSA. As such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Computational Biologist participates in developing, improving and maintaining bioinformatics tools for high-throughput processing pipelines. The Computational Biologist specifies, implements, tests and maintains bioinformatics computer applications and systems, and participates in the code walk-throughs and design and review of bioinformatics software solutions. The Computational Biologist will also assist in the packaging and distribution of developed tools and analysis results to the scientific community, and will contribute to the preparation of scientific publications.

Duties

Codes in Python and specifies, implements, tests, and maintains bioinformatics pipelines and applications as assigned. Assists with devising or modifying systems to solve complex problems associated with high throughput pipelines, considering computer equipment capacity and limitations, operating time and form of desired results. Participates in code walk-throughs and reviews of the coded solutions to PEP8 standards. Participates in the design and build of database and software solutions taking performance into consideration. Coordinates production problem resolution for assigned applications, including working with other technical teams. Evaluates third-party software and incorporates new systems into legacy systems. Produces written documentation of algorithms, validations, SOPs, and other processes related to pipeline updates and procedures as required. Presents results of bioinformatics software testing internally and externally. Performs literature searches, testing and validation of new data analysis software related to bioinformatics pipelines. Performs other related duties as required.

Qualifications

Education, Training and Experience

• Graduation from a recognized Bachelor of Applied Science or Bachelor of Science Program in either Computer Science, Biological Sciences, or equivalent program.
• Two (2) years of recent related experience in a bioinformatic setting or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

• Demonstrated expertise with Python or other similar high level languages for application in data analysis.
• Demonstrated ability to program and run analysis in a high throughput bioinformatics production environment.

• Functional knowledge of distributed version control systems, such as GIT.
• Functional knowledge of Agile development and ticketing systems.
• Demonstrated ability to work with bioinformatics workflow managers (e.g. Nextflow).

• Excellent verbal and written communication skills.
• Demonstrated ability to work in an Unix environment, including experience with shell scripting and common command-line tools.
• Demonstrated ability to develop software as part of a team.
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
• Demonstrated ability to efficiently organize work assignments and establish priorities.

Benefits

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• Enjoy a comprehensive benefits package, which includes statutory benefits - Canada Pension Plan, Employment Insurance and WorkSafe BC plus the BC Cancer group benefits plan which includes medical & dental extended health, and group life insurance coverage, and psychological health & safety programs and holistic wellness resources.
• Annual statutory holidays (13) with generous vacation entitlement and accruement.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: 

Temporary, Full-Time with an opportunity for Regular Full Time employment, 7.5 hrs. per day

Salary Range: 

$35.52 to $44.33 per hour for 6th year. The starting salary for this position would be determined with consideration of the successful candidate’s relevant education and experience, and would be in alignment with the provincial compensation reference plan.  

Application

As this is a union position, you will also have to apply either as an internal or external applicant through http://www.phsa.ca/careers using the posting reference 154623.

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: CB_P01066_Software Development_HSA154623_2023_10_24 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are onsite positions based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Staff - Non Union

Job Category

Non Union Technicians and Research Assistants

Job Profile

Non Union Salaried - Research Assistant /Technician 4

 

Job Title

Research Assistant/Tech 4 - Single Cell Genomics / Molecular Biologist

 

Department

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine

 

Compensation Range

$4,558.75 - $5,354.67 CAD Monthly

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

The anticipated start date for this position is Oct 3, 2023. The term is for one year with the possibility of extension.

In your application please include (1) a cover letter, and (2) a CV or resume.

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career. 

Job Summary

The Aparicio lab is developing new single-cell genome and transcriptome methods for tracking clonal trajectories at the single-cell level in patient tissues and to gain a better understanding of the tumour microenvironment. Our researchers use the latest single-cell genomics technologies to rapidly identify genes that are involved in the development of cancer. This position will be working on the Single-Cell Genomics Platform on research projects currently ongoing in the lab. The successful candidate will be providing technical guidance, expertise, technology development and support to both internal/external researchers using the single-cell genomics platform; located at 2 separate research facilities in Vancouver, B.C.

We are seeking a highly-motivated and highly skilled individual with expertise or experience in single-cell genomics, liquid handling robotics, and/or next-generation sequencing with a strong background in molecular biology. The successful applicant will work full-time under the direction and supervision of Dr. Samuel Aparicio, Principal Investigator, and his designate. Individuals with experience using liquid handling robotics are considered an asset. Experience with bioinformatics approaches to biological data and familiarity with the handling of genomics and next-generation sequencing data will be an advantage. This position will provide the candidate with a high leel of exposure to single-cell genomics and translational research, as well as, providing opportunities to work collaboratively with industry partners and other researchers globally; the position start date is flexible.

Organizational Status
Aparicio Lab is located in the department of Molecular Oncology at BC Cancer Research Institute in Vancouver, British Columbia, Canada. The candidate will report directly to Dr. Samuel Aparicio, or Laboratory Research and Operations Manager, in addition, the applicant may assist in overseeing the technical work of students and trainees.

Work Performed

• Plans and performs experiments utilizing established complex procedures and/or techniques for investigating single-cell genomics, involving the use of liquid handling robotics and 10x genomics platforms.
• Collaborates with PI and team members to support the development project pipelines, and technical experiments.   
• Visualize and analyze cells using microscopy and flow cytometry.
• Generation, preparation and submission of next-generation sequencing libraries.
• Using an LMIS system to track and record sample data
• Provide technical expertise and support in molecular biology, protein biochemistry, tissue culture and virology
• Develop and implement standard operating protocols (SOPs).
• Maintains laboratory records and experimental data.
• Assist in general lab maintenance such as reagent preparation, receiving and inventory of lab supplies.
• Conducts complex data analysis and interpretation of data resulting from high throughput experiments.
• Presents data at scientific meetings, writes reports and contributes to writing ethics and grant applications.
• Carries out any other related duties as assigned or required in keeping with the qualifications and requirements of this technician level.

Consequence of Error/Judgement
The work is complex and required a high level of training, tasks are assigned and the incumbent exercises a considerable amount of responsibility, initiative and judgment in determining their work schedule to achieve those tasks. Errors may result in the permanent loss of irreplaceable tissue samples, loss of thousands of dollars of material and/or damage to equipment.  Incorrect decisions or actions may damage the reputation of the laboratory, lead to a loss of credibility in this field, and be financially costly. Noncompliance with biosafety and chemical safety regulations may also result in the closure of the facility or loss of grant funding.

Supervision Received
The successful applicant will work under minimum supervision. From time to time, Principal Investigator or Laboratory Research and Operations Manager may provide specific instructions on unusual problems or new project outlines. This position will report to the Principal Investigator or Laboratory Research and Operations Manager.   

Supervision Given
Depending on experience and expertise, the successful applicant may be required to assist in the training and supervision of graduate students/trainees, junior staff, or external collaborators; including providing instruction on the use of lab equipment and procedures, and will help troubleshoot experiments in their area of expertise.

Minimum Qualifications
Completion of a university degree in a relevant discipline or technical program and a minimum four years of related experience or an equivalent combination of education and experience. Some positions may require a graduate degree.

- Willingness to respect diverse perspectives, including perspectives in conflict with one’s own

- Demonstrates a commitment to enhancing one’s own awareness, knowledge, and skills related to equity, diversity, and inclusion

Preferred Qualifications

• An MSc in Biological Sciences (Molecular Biology or other relevant fields) with work experience in single cell genomics biology, next-generation sequencing or molecular biology, preferred
• Working knowledge and understanding of molecular biology and biochemistry techniques such as next-generation sequencing, PCR, DNA/RNA purification and molecular cloning techniques are essential; prior working experience in next-generation sequencing and library construction is considered a great asset.
• Experience with cell culture and aseptic technique.
• Working hands-on experience in tissue handling and tissue dissociation methods would be an asset.
• Ability to perform and troubleshoot a wide variety of molecular and cellular biology techniques including the following: RNA / DNA isolation, quantitative PCR, transfection, flow cytometry, immunohistochemistry, ELISA, protein isolation, and western blotting.
• Preference will be given to applicants with liquid handling robotics, single-cell genomics, next-generation sequencing, and 10x Genomics experience.
• Experience in immunocytochemistry and basic data analysis in R or similar statistics package would be an asset.
• Demonstrated understanding of experimental design and assay optimization.
• Strong interpersonal skills, communication skills (orally and written) and the ability to interact positively and productively with other team members are essential.
• Excellent documentation and organizational skills.
• Able to multi-task, prioritize and handle multi-project assignments concurrently.
• The successful candidate must be well-organized, conscientious, understand the importance of detail, and be able to multi-task and prioritize duties effectively.

Staff - Non Union

 

Job Category

Non Union Technicians and Research Assistants

Job Profile

Non Union Salaried - Research Assistant /Technician 3

 

Job Title

Research Assistant/Tech 3 - Aparicio

 

Department

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine

 

Compensation Range

$3,982.67 - $4,703.83 CAD Monthly

 

Posting End Date

September 25, 2023

Note: Applications will be accepted until 11:59 PM on the day prior to the Posting End Date above.

Job End Date

Oct 24, 2024

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

The anticipated start date for this position is October 23 , 2023. The term is for one year with the possibility of extension.

In your application please include (1) a cover letter, and (2) a CV or resume.
 

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career. 

Job Summary

The Aparicio lab is developing new single-cell genome and transcriptome methods for tracking clonal trajectories at the single-cell level in patient tissues and to gain a better understanding of the tumour microenvironment. Our researchers use the latest single-cell genomics technologies to rapidly identify genes that are involved in the development of cancer. This position will be working on the Single-Cell Genomics Platform on research projects currently ongoing in the lab. We are seeking a highly-motivated, detailed, organized, and driven individual with an interest or experience in molecular biology, single-cell genomics, liquid handling robotics, and/or next-generation sequencing.

This entry-level position will provide candidates with an opportunity to work and learn within an academic research environment where continual training and learning are greatly encouraged. The core focus of this position will be providing technical assistance/support on molecular biology, tissue culture, next-generation library preparation and the operations of highly sensitive liquid handling robotics to support current internal/external researchers using the single-cell genomics platform. Hands-on training will be provided to the successful candidate.

This position will provide the candidate with a high level of exposure to single-cell genomics and translational research, as well as, providing opportunities to work collaboratively with industry partners and other researchers globally; the position start date is flexible.

Organizational Status
Aparicio Lab is located in the department of Molecular Oncology at BC Cancer Research Institute in Vancouver, British Columbia, Canada. The successful applicant will report to the Principal Investigator or his/her delegate.

Work Performed

• Plans and performs experiments utilizing established SOPs for investigating single-cell genomics, involving the use of liquid handling robotics and 10x genomics platforms

• Visualize and analyze cells using microscopy and flow cytometry.

• Generation, preparation and submission of next-generation sequencing libraries.

• Using an LMIS system to track and record sample data

• Assist and provide support in molecular biology, tissue culture and next-generation sequencing to other senior searchers

• Assist in developing and implementing standard operating protocols (SOPs).

• Maintains laboratory records and experimental data.

• Assist in general lab maintenance such as reagent preparation, receiving and inventory of lab supplies.

• Present experimental data at internal scientific project meetings.

• Carries out any other related duties as assigned or required in keeping with the qualifications and requirements of this technician level.

Consequence of Error/Judgement
The work is complex and required a high level of training, tasks are assigned and the incumbent exercises a considerable amount of responsibility, initiative and judgment in determining their work schedule to achieve those tasks. Errors may result in the permanent loss of irreplaceable tissue samples, loss of thousands of dollars of material and/or damage to equipment.  Incorrect decisions or actions may damage the reputation of the laboratory, lead to a loss of credibility in this field, and be financially costly. Noncompliance with biosafety and chemical safety regulations may also result in the closure of the facility or loss of grant funding.

Supervision Received
The successful applicant will work under general supervision; receives detailed instructions on the assignment of new duties and thereafter only on new or unusual problems. From time to time, Principal Investigator or Laboratory Research and Operations Manager may provide specific instructions on unusual problems or new project outlines. This position will report to the Principal Investigator or Laboratory Research and Operations Manager.  

Supervision Given
Depending on experience and expertise, the successful applicant may be required to assist in the training and supervision of graduate students/trainees, junior staff, or external collaborators; including providing instruction on the use of lab equipment and procedures, and will help troubleshoot experiments in their area of expertise.

Minimum Qualifications
Completion of a relevant technical program or a university degree in a relevant discipline and a minimum three years of related experience or an equivalent combination of education and experience.

- Willingness to respect diverse perspectives, including perspectives in conflict with one’s own

- Demonstrates a commitment to enhancing one’s own awareness, knowledge, and skills related to equity, diversity, and inclusion

Preferred Qualifications

• A BSc or MSc in Biological Sciences (Molecular Biology or other relevant fields) with work experiences in single-cell genomics biology, next-generation sequencing or molecular biology, preferred

• Working knowledge and understanding of molecular biology techniques such as next-generation sequencing, PCR, DNA/RNA purification and molecular cloning; prior working experience in next-generation sequencing and library construction is considered a great asset.

• Experience with cell culture and aseptic technique.

• Working hands-on experience in tissue handling and tissue dissociation methods would be an asset.

• Preference will be given to applicants with liquid handling robotics, single-cell genomics, next-generation sequencing, and 10x Genomics experience.

• Experience in immunocytochemistry and basic data analysis in R or similar statistics package would be an asset.

• Demonstrated understanding of experimental design and assay optimization.

• Strong interpersonal skills, communication skills (orally and written) and the ability to interact positively and productively with other team members are essential.

• Excellent documentation and organizational skills.

• Able to multi-task, prioritize and handle multi-project assignments concurrently.

• The successful candidate must be well-organized, conscientious, understand the importance of detail, and be able to multi-task and prioritize duties effectively.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No. RP_R00008_VarDB_2023_08_25

Summary

The Software Developer to join the bioinformatics databases team at the Genome Sciences Centre (GSC) will work on developing databases and applications at the GSC, including the Hadoop-based VarDB, graphDB knowledgebase, and clinical databases. Strong Python and node.js server side application skills are required. The role is ideally suited for a creative individual with a strong interest in software development and testing, database development, and automation within a high throughput academic setting. General understanding of clinical or biological data would be an asset.

Duties/Accountabilities:

• Design, plan, and implement web applications and databases
• Work with other project team members to develop and test code, and implement software
• Evaluate third-party software and incorporate new systems into legacy systems
• Produce thorough but concise written documentation of algorithms, validations, SOPs, and other processes and procedures as required.

Qualifications:

• Graduation from a recognized Bachelor of Science Program in Computer Science. A Master’s degree in a relevant field would be a strong asset.
• Two (2) years of recent related experience or an equivalent combination of education, training and experience acceptable to the project lead.

Skills and Abilities:

• Functional knowledge of distributed version control systems, such as SVN or GIT
• Expertise with Python 3.X and able to provide links to code samples via github or other open repository
• Express.js, Node.js and React.js programming
• Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools
• Familiarity with Agile software practices
• Familiarity with the development, testing, and maintenance of relational databases
• Experience with software testing
• Able to collaborate and write software in a team environment
• General biological scientific background or experience would be an asset
• Able to write in concise but precise prose
• Excellent verbal and written communication skills
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment
• Demonstrated ability to efficiently organize work assignments and establish priorities

Benefits

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• Enjoy a comprehensive benefits package, which includes statutory benefits - Canada Pension Plan, Employment Insurance and WorkSafe BC plus the BC Cancer group benefits plan which includes medical & dental extended health, and group life insurance coverage, and psychological health & safety programs and holistic wellness resources.
• Annual statutory holidays (13) with generous vacation entitlement and accruement.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: 

Temporary, Full-Time, 7.5 hrs. per day

Salary Range: 

$65,884 - $94,709 p.a.. The starting salary for this position would be determined with consideration of the successful candidate’s relevant education and experience, and would be in alignment with the provincial compensation reference plan.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No. RP_R00008_VarDB_2023_08_25 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.  ABC_P00183_JR# 150051_CCGI_2023_08_08

Summary

Canada’s Michael Smith Genome Sciences Centre (GSC) of the BC Cancer Research Institute is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility in one of the most beautiful, diverse and eclectic cities in the world.

As an Assistant Bioinformatics Coordinator in the Clinical Panels Informatics team at the GSC, you will be responsible for supervising, coordinating and supporting activities related to clinical panel informatics through process monitoring, auditing and reporting as well as development, testing and validation of new clinical bioinformatics processes. The Assistant Bioinformatics Coordinator will report to the Bioinformatics Coordinator and is anchored within a team of exceptional computational scientists and programmers, who collaborate directly on the development and maintenance of robust, cost efficient, and competitive clinical genomics pipelines. By working within the GSCs bioinformatics facility, you will collaborate with clinical and research computational biologists and programmers across bioinformatics groups, clinical lab staff and the quality assurance group to deliver clinical diagnostic genomic testing for patients in BC.

Duties and Responsibilities:

1. Assists the Bioinformatics Coordinator in the day to day activities of the Bioinformatics group by performing duties such as providing input on quantity and quality of work, making recommendations for improvements, workflow and procedures.
2. Coordinates projects of the Bioinformatics group by performing duties such as chairing project-specific meetings and provides project status reports to the Bioinformatics Coordinator, with suggestions towards any required improvement of project management, task allocation and overall process.
3. Develops and implements assays to monitor project progress and measure project accomplishments to ensure that appropriate project focus is maintained and to provide feedback to staff.
4. Provides supervisory support to the Bioinformatics group by performing duties such as:

         a.   Orientating new staff.

         b.   Providing input to the Bioinformatics Coordinator on training requirements.

         c.   Providing input to the Bioinformatics Coordinator on the establishment of clear definitions of responsibility for employees.

         d.   Assigning workload assignments and establishing work schedules.

         e.   Reviewing and establishing work priorities and adjusting work schedules to ensure clinical priorities are met.

         f.    Completing performance reviews and addressing performance issues in conjunction with the Bioinformatics Coordinator.

5.         Participates in the recruitment of staff through methods such as interviewing internal and external applicants and forwards hiring recommendations.

6.         Participates in the implementation of quality improvement programs to ensure clinical assays are provided in the most efficient and effective way by performing duties such as:

         a.         Monitoring quality and quantity of service and information provided by the bioinformatics group and identifying areas for change and/or improvement.

         b.         Generating quality metrics and reports to evaluate quality and robustness of clinical bioinformatic pipelines

         c.      Develops clear and concise documentation

7.         Assesses practical needs for identified clinical priorities for GSC in conjunction with the Bioinformatics Coordinator and Analysis Group Leader.

8.         Participates in a variety of meetings by performing duties such as providing and/or receiving information and contributing to decision making.

9.         Participates, in conjunction with the Bioinformatics Coordinator, in determining the computer infrastructure necessary for successful completion of projects and ensured viability of research programs by performing duties such as providing input and recommendations regarding purchasing decisions related to hardware, software and related items for the clinical bioinformatics platform.

10.       Interprets statistical analyses and makes recommendations for review including preparing reports on statistical findings for publication and presentation both internally and externally of the GSC.

11.       Generates specification for pipeline improvements/implementations such as determining user requirements, examining and identifying problems with existing systems and recommending modifications to and/or new systems; provides details of cost benefit analysis

12.       Performs technical functions related to the bioinformatic functions of the GSC.

13.       Performs other related duties as required.

Qualifications

Education, Training and Experience

• Graduation from a recognized Bachelor’s program in a related discipline such as Biochemistry, Genetics, Computer Science.  A minimum of four (4) years of recent related experience in a research and or clinical laboratory including experience in computer programming and quantitative data analysis, handling next generation sequencing data, database development and data storage schemas or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

• Comfortable working in a Linux environment, including experience with shell scripting and common command-line tools.
• Proven expertise with Python, R, and/or other similar high-level languages
• Functional knowledge of distributed version control systems, such as Git.
• Demonstrated experience with analysis of next generation sequencing data with an understanding of standards and guidelines for validating clinical bioinformatics analysis pipelines using these technologies.
• Demonstrated ability to accept responsibility and work independently.
• Demonstrated ability to work effectively with others in a team environment.
• Demonstrated ability to supervise staff and to efficiently organize work assignments and establish priorities to meet set milestones.
• Excellent organizational, leadership interpersonal and communication skills.
• Demonstrated ability to write technical documents including validations and procedure manuals.
• Experience with bioinformatics workflow managers and database development would be considered an asset.
• Physical ability to perform the duties of the job.

Benefits

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• Enjoy a comprehensive benefits package, which includes statutory benefits - Canada Pension Plan, Employment Insurance and WorkSafe BC plus the BC Cancer group benefits plan which includes medical & dental extended health, and group life insurance coverage, and psychological health & safety programs and holistic wellness resources.
• Annual statutory holidays (13) with generous vacation entitlement and accruement.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: 

Regular, Full-Time, 7.5 hrs. per day

Wage: 

$38.11 to $47.46 p.a. for 6th year.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using ABC_P00183_JR# 150051_CCGI_2023_08_08 in the subject line of your email.

As this is a union position, you will also have to apply either as an internal or external applicant through http://www.phsa.ca/careers using the posting reference 150051.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

What you’ll do

• In collaboration with the Principal Investigator(s) (PIs), coordinate the preparation and submission of grant proposals.
• Interact with both national and international universities and granting agencies. Ensure flow of information with internal and external stakeholders regarding grant related matters and make arrangements for visiting speakers and guests.
• Coordinate registration and travel arrangements for staff attendance at seminars and meetings. This includes completing registration (on-line or phone), abstract submission, making travel and lodging reservations, culminating expense reimbursements to the attendee and/or cost recovery from the conference organizers.
• Human resource responsibilities include recruitment of staff by posting/advertising internally and externally (UBC), coordinating interviews and screening applications for review by hiring supervisors. Manage new hire orientation process and ensure all safety and personnel documentation is in place according to policies, guidelines and legislations.
• Ensure all hiring, appointment and payroll processes are complete for employees. Liaise with various PHSA units such as Payroll and Human Resources and in some cases, UBC, to ensure a seamless process and minimize errors.
• Act as the main contact for ordering lab and office supplies for the department. Manage and process various requisitions such as travel, expense reimbursements, cheque requests, and honorariums for the Department Head and PIs. 

 

What you bring

• A level of education, training, and experience equivalent to a Diploma in a relevant area such as business administration or finance from a recognized college.
• Three (3) years’ recent, related experience a research environment and in project management.
• Strong interpersonal and communication skills and the ability to demonstrate good judgment, tact and discretion.
• Demonstrated time management skills and the ability to assist others in meeting deadlines.
• Demonstrated ability to make sound decisions and resolve administrative issues/problems.
• Detail orientation and the ability to complete accurate work in a timely matter.
• Knowledge of and experience with grant applications. Knowledge and experience in budget preparation, tracking expenditures and identifying sources of variance.
• Commitment to upholding the shared responsibility of creating lasting and meaningful reconciliation in Canada as per TRC (2015) and BC's Declaration on the Rights of Indigenous Peoples Act (2019).
• Knowledge of social, economic, political and historical realities impacting indigenous communities and familiarity with Indigenous Cultural Safety and anti-racism and accompanying reports (BC DRIPA, TRC, etc.).

What we bring

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• Enjoy a comprehensive benefits package, including municipal pension plan, and psychological health & safety programs and holistic wellness resources.
• Annual statutory holidays (13) with generous vacation entitlement and accruement.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: Regular, Full-Time

Salary Range: $51,156 - $68,455 per year. The starting salary for this position would be determined with consideration of the successful candidate’s relevant education and experience, and would be in alignment with the provincial compensation reference plan. Salary will be prorated accordingly for part time roles.

Location: 675 W 10th Ave, Vancouver, BC V5Z 1G1 / This position can be hybrid.

Applications will be accepted until position is filled.

Hours of Work: Monday to Friday; 0830-1630

Requisition # 148648

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

 

What we do

BC Cancer provides comprehensive cancer control for the people of British Columbia. BC Cancer is part of the Provincial Health Services Authority (PHSA).

(PHSA) plans, manages and evaluates specialized health services with the BC health authorities to provide equitable and cost-effective health care for people throughout the province. Our values reflect our commitment to excellence and include: Respect people – Be compassionate – Dare to innovate – Cultivate partnerships – Serve with purpose.

Learn more about PHSA and our programs: jobs.phsa.ca/programs-and-services

PHSA and BC Cancer are committed to employment equity, encouraging all qualified individuals to apply. We recognize that our ability to provide the best care for our diverse patient populations relies on a rich diversity of skills, knowledge, background and experience, and value a safe, inclusive and welcoming environment.

Reconciliation is an ongoing process and a shared responsibility for all of us. The BC Governments’ unanimous passage of the Declaration on the Rights of Indigenous Peoples Act was a significant step forward in this journey—one that all health authorities are expected to support as we work in cooperation with Indigenous Peoples to establish a clear and sustainable path to lasting reconciliation. True reconciliation will take time and ongoing commitment to work with Indigenous Peoples as they move toward self-determination. Guiding these efforts Crown agencies must remain focused on creating opportunities that implement the Truth and Reconciliation Commission Mandate.

What you’ll do

• In collaboration with the Principal Investigator(s) (PIs), coordinate the preparation and submission of grant proposals.
• Interact with both national and international universities and granting agencies. Ensure flow of information with internal and external stakeholders regarding grant related matters and make arrangements for visiting speakers and guests.
• Coordinate registration and travel arrangements for staff attendance at seminars and meetings. This includes completing registration (on-line or phone), abstract submission, making travel and lodging reservations, culminating expense reimbursements to the attendee and/or cost recovery from the conference organizers.
• Human resource responsibilities include recruitment of staff by posting/advertising internally and externally (UBC), coordinating interviews and screening applications for review by hiring supervisors. Manage new hire orientation process and ensure all safety and personnel documentation is in place according to policies, guidelines and legislations.
• Ensure all hiring, appointment and payroll processes are complete for employees. Liaise with various PHSA units such as Payroll and Human Resources and in some cases, UBC, to ensure a seamless process and minimize errors.
• Act as the main contact for ordering lab and office supplies for the department. Manage and process various requisitions such as travel, expense reimbursements, cheque requests, and honorariums for the Department Head and PIs. 

 

What you bring

• A level of education, training, and experience equivalent to a Diploma in a relevant area such as business administration or finance from a recognized college.
• Three (3) years’ recent, related experience a research environment and in project management.
• Strong interpersonal and communication skills and the ability to demonstrate good judgment, tact and discretion.
• Demonstrated time management skills and the ability to assist others in meeting deadlines.
• Demonstrated ability to make sound decisions and resolve administrative issues/problems.
• Detail orientation and the ability to complete accurate work in a timely matter.
• Knowledge of and experience with grant applications. Knowledge and experience in budget preparation, tracking expenditures and identifying sources of variance.
• Commitment to upholding the shared responsibility of creating lasting and meaningful reconciliation in Canada as per TRC (2015) and BC's Declaration on the Rights of Indigenous Peoples Act (2019).
• Knowledge of social, economic, political and historical realities impacting indigenous communities and familiarity with Indigenous Cultural Safety and anti-racism and accompanying reports (BC DRIPA, TRC, etc.).

What we bring

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• Enjoy a comprehensive benefits package, including municipal pension plan, and psychological health & safety programs and holistic wellness resources.
• Annual statutory holidays (13) with generous vacation entitlement and accruement.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: Temporary

Salary Range: $57,347 - $75,268 per year. The starting salary for this position would be determined with consideration of the successful candidate’s relevant education and experience, and would be in alignment with the provincial compensation reference plan. Salary will be prorated accordingly for part time roles.

Location: 675 W 10th Ave, Vancouver, BC V5Z 1G1

Applications will be accepted until position is filled.

Hours of Work: Monday to Friday; 0830-1630

Posting # 168888-2420250

Job Category

Non Union Technicians and Research Assistants

Job Profile

Non Union Salaried - Research Assistant /Technician 3

 

Job Title

Research Assistant/Tech 3 - Sorensen

 

Department

Sorensen Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine

 

Compensation Range

$3,982.67 - $4,703.83 CAD Monthly

 

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

The anticipated start date for this position is July 4, 2023. The term is for one year with the possibility of extension.

In your application please include (1) a cover letter, and (2) a CV or resume.

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career. 

Job Summary

The basic and translational research performed in the Sorensen laboratory seeks to improve basic knowledge and treatment options in Ewing sarcoma and other high-risk pediatric cancers. This position will mainly work on the characterization of pathways facilitating adaptation of pediatric cancer cells to stress and promoting metastasis.

The Research Assistant (RA) will be responsible, under supervision, for laboratory work including biochemical, molecular, and cell-based analyses, and in vivo mouse procedures.

Organizational Status
The Sorensen Lab is located at the BC Cancer Research Centre. The RA reports directly to the Primary Investigator and different study leads within the research group. The position requires to use a high degree of initiative, tact and professional judgement in carrying out responsibilities related to the research. The incumbent will also be required to report to the primary investigator and study leads in a clear and timely manner.

Work Performed

Laboratory Research Duties:

• The incumbent will be responsible for laboratory duties which include, but not limited to, western blotting, immunoprecipitation, PCR and RT-PCR, plasmid preparation, bacterial culture, general buffer preparation, and mammalian/cancer cell culture, mammalian transfection/lentiviral transduction, immunofluorescent staining, microscopy, and cellular/molecular biology (cell proliferation, death, cytotoxicity, etc.), preparing samples for proteomics (e.g. mass spectrometry). Training for additional research techniques will be provided as needed.
• In addition to general laboratory duties, the incumbent will divide their bench time among several concurrent projects, thus efficient time management of bench work to various projects will be an asset.

Animal Research Duties:

• Maintains current knowledge of, and ensures compliance with, animal care regulations. As part of this, the incumbent will acquire animal research center handling and certification of techniques and procedures as it relates to required mouse work.
• Maintains daily care of laboratory mice including, primary tumour caliper measurements, and logging changes in animal health and general health conditions. The incumbent will also keep an up-to-date record of mice and mouse cages using Mosaic software.
• Performs mouse surgeries and techniques including blood collection, tumour implantation, injection of tumor cells (subcutaneous and tail-vein injections), saline/vehicle solutions, and investigational anti-cancer drugs. The incumbent will be also responsible for small animal bioluminescence (IVIS) imaging of mouse tumours, and other organs, as well as harvesting of mouse tissues.
• The incumbent will also perform ancillary laboratory techniques such as media/drug preparation, cell culture, instrument sterilizations, polymerase chain reaction analysis (for genotyping), and receiving and processing laboratory animal care supplies.

Consequence of Error/Judgement
When dealing with laboratory chemicals, the incumbent will exercise judgement based on the Biosafety and Laboratory Safety provided by online training modules. The incumbent is expected to exercise good judgment at all times and if in doubt seek advice from those that she/he may report to.

Supervision Received
The Research Assistant will work mostly independently from day to day. The Research Assistant will be supervised by the Principal Investigator with additional guidance provided by the study leads, and will be expected to report his/her results to them regularly.

Supervision Given
The Research Assistant is not required to directly supervise anyone. She/he may be required to allow a student or new staff member to shadow them, or serve as a resource for undergraduate students.

Minimum Qualifications
Completion of a relevant technical program or a university degree in a relevant discipline and a minimum three years of related experience or an equivalent combination of education and experience.

- Willingness to respect diverse perspectives, including perspectives in conflict with one’s own

- Demonstrates a commitment to enhancing one’s own awareness, knowledge, and skills related to equity, diversity, and inclusion

Preferred Qualifications

• Undergraduate degree in a Medical/Health Science discipline preferred.
• Experience in laboratory bench work from the same or similar research field would be a key asset.
• Knowledge of scientific terminology and familiarity with research study protocols, ethics approval processes, and previous experience with mouse models and proteomics techniques are also an asset.
• Ability to work independently and collaboratively.
• Excellent communication skills are required, including effective inter-personal, oral and listening skills.
• Attention to details.
• Good organizational skills are essential to plan experiments efficiently, track progress and provide clear and timely updates to study team members.

Three graduate student positions are available at the Department of Molecular Oncology, BC Cancer Research Institute for the development of novel radiopharmaceuticals for detection and radioligand therapy of cancer. The graduate student candidates will register through the Interdisciplinary Oncology Program (www.iop.ca), University of British Columbia, and pursue either an MSc or PhD degree.

The student candidates will conduct research on the design and synthesis of imaging probes and radiotherapeutic agents targeting biomarkers overexpressed in cancers. Research activities will involve the production and isolation of radioisotopes, peptide and multi-step organic synthesis, and radiolabeling small molecules/peptides/antibodies for PET/CT and SPECT/CT imaging, biodistribution, and radioligand therapy studies in various animal models.

Qualified candidates should have a bachelor degree preferably in chemistry, biology or pharmacy with interest in the development of cancer-targeted radiopharmaceuticals. The ability to conduct research in a collaborative environment is required including good oral and written communication skills in English. For more information regarding application for the Interdisciplinary Oncology Program at the University of British Columbia, please check the following website: www.iop.ca

Before applying, interested student candidates should first contact:

Dr. Kuo-Shyan Lin

Senior Scientist, BC Cancer Research Institute

Associate Professor, University of British Columbia

E-mail: klin@bccrc.ca

Job Category:

Faculty Non Bargaining

Job Title:

Research Associate - Bioinformatics

Department:

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine (Samuel Aparicio)

 

Job Summary:

The Aparicio lab is seeking a Bioinformatics Research Associate to join our dynamic and accomplished team, renowned for its contributions to breast oncology research. Our lab's success stems from a combination of technical excellence, hard work, and a global network of outstanding collaborators from Canada, the United States, and the United Kingdom, all working together to advance our understanding of the evolution of breast, ovarian, and other cancers.

As part of the University of British Columbia and the BC Cancer Research Centre, the Aparicio lab benefits from the abundant biomedical resources available at these institutions. These resources have enabled our team to develop expertise in techniques ranging from CRISPR gene editing to spatial imaging and single molecule sequencing. As a result, our trainees have had the opportunity to share their work in esteemed journals like Nature, Nature Cancer, and Cell in recent years.

In this role, the Bioinformatics Research Associate will primarily focus on leading and participating in projects that investigating functional genomics using sequencing and expression data for breast oncology and cancer evolution.

This position offers a unique opportunity for mentoring trainees, supervising staff, and interacting with industry professionals, providing an ideal platform to develop the essential skills for a successful medical research career in academia or industry. As a Research Associate at the University of British Columbia, you will thrive under the guidance of an exceptional mentor within the supportive environment of the BC Cancer Research Centre.

This position is located within a health-care facility. Therefore, this position requires successful verification of full vaccination against COVID-19 provided prior to the start date, as required by the provincial health mandate.

The UBC Department of Pathology and Laboratory Medicine is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients. The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence.

ORGANIZATIONAL STATUS

The researcher associate will play a leadership role in the Aparicio lab, and will be reporting directly to Dr. Samuel Aparicio who is the primary investigator of the laboratory.

WORK PERFORMED

• Planning and designing of experiments;
• Analyzing, interpreting and compiling data in study reports, presenting results, and participating in the preparation of scientific manuscripts and grant application packages
• Updating Dr. Aparicio and the group on the status of projects during lab meetings, in email correspondence and phone conferences;
• Managing projects with key academic and industry partners.
• Performing regular reviews of the relevant literature;
• Management and supervision of trainees;
• May be involved in recruitment and training of trainees;

CONSEQUENCE OF ERROR

Accountable for the management and progress of research projects.  Errors in judgment may cause severe impact to research progress, reputational good standing and international collaborations.

SUPERVISION RECEIVED

Works independently under direction of PI, Dr. Samuel Aparicio Opportunities to work collaboratively with Industry partners and other researchers at UBC and globally

SUPERVISION GIVEN

Assists and oversees research assistants and students as required.  Assists and provides guidelines to other research members, as required

MINIMUM QUALIFICATIONS

• PhD degree in the computer science, bioinformatics or equivalent
• At least 4 years experience in bioinformatics research
• Expertise in next-generation sequencing genomics and transcriptomics
• Demonstrated success in computational academic research
• Proven ability to multi-task in a deadline oriented environment with minimal supervision
• Excellent organizational skill and ability to learn new skills quickly

PREFERRED QUALIFICATIONS

• Extensive knowledge of cellular and molecular biology, biochemistry and genetics
• Experience with cancer research
• Outstanding oral and written communication, analytical, and interpersonal skills
• Ability to work independently and within a team environment.
• The ability to balance a broad strategic vision with attention to detail
• Candidates should demonstrate the ability to work in a highly interdisciplinary environment.

Become a part of our dedicated team as we continue to break new ground in cancer research and translate our findings into meaningful advancements in patient care. Apply now to contribute your skills and enthusiasm to the Aparicio lab, and help shape the future of oncology research.

Three postdoctoral fellow positions are immediately available at the BC Cancer Research Institute in Vancouver, Canada for the development of novel radiopharmaceuticals for cancer imaging and radioligand therapy. The postdoctoral fellows will conduct research in the design and synthesis of radioligands targeting biomarkers overexpressed in cancers. Research activities will involve the production and isolation of radioisotopes, peptide and multi-step organic synthesis, and radiolabeling small molecules, peptides and antibodies with various imaging and radiotherapeutic isotopes (F-18, Ga-68, Zr-89, Tc-99m, I-123, In-111, Lu-177, Ac-225 …).

Qualified candidates should have a PhD degree in radiochemistry, organic or medicinal chemistry with experience in peptide or multi-step organic synthesis. Experience with HPLC, micro-scale reactions, and radiochemistry is strongly desirable but not required. The ability to perform research in a collaborative environment is required including excellent oral and written communication skills. This joint position between BC Cancer Research Institute and University of British Columbia (UBC) is for a period of two years with the possibility of renewal.

Interested candidates should send a letter of application, curriculum vitae, and names of three references to both Dr. Kuo-Shyan Lin (klin@bccrc.ca) and Dr. François Bénard (fbenard@bccrc.ca). Review of applications will begin immediately and will continue until the position is filled.

Advancing Genomics Technologies for Health and Life Sciences

The Michael Smith Genome Sciences Centre (GSC), a provincial program within the Provincial Health Services Authority (PHSA), is a recognized international leader in genomics, bioinformatics, and genome technology innovation. By developing and deploying cutting-edge sequencing and computational platforms, the GSC supports breakthrough research across cancer, rare and infectious diseases, and the broader life sciences. Our work enables earlier diagnosis, novel therapeutic approaches, and transformative applications of genomics to improve human health and environmental resilience—delivering both social and economic impact through science.

Job Reference No: RP_R00008_CCGI_2026_01_14

Summary

Canada’s Michael Smith Genome Sciences Centre (GSC) of the BC Cancer Research Institute is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility in one of the most beautiful, diverse and eclectic cities in the world.

As a Research Programmer within the Centre for Clinical Genomics Informatics team at the GSC, you will be responsible for technical support for clinical programs through development, testing and validation of clinical bioinformatics processes. The Research Programmer will report to the Process Development Coordinator and is anchored within a team of exceptional computational scientists and programmers, who collaborate directly on the development and maintenance of robust, cost efficient, and competitive clinical genomics pipelines. By working within the GSCs bioinformatics facility, you will collaborate with clinical and research computational biologists and programmers across bioinformatics groups, clinical lab staff and the quality assurance group to deliver clinical diagnostic genomic testing for patients in BC.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities. 

So, what are you waiting for? Apply now!  

Please note that we are recruiting for two (2) candidates for this role.

Duties and Responsibilities:

• Works with team members to identify and implement pipeline improvements to optimize existing clinical pipelines.
• Works with stakeholders to design, plan and implement testing and development of new clinical bioinformatics software.
• Development and maintenance of clinical genomic databases.
• Delivery of clear and concise documentation.
• Actively participate in a team-oriented approach to improve efficiency and productivity.

Qualifications

• Graduation from a recognized Bachelor’s program in an appropriate discipline such as Computer Science, Bioinformatics, Genetics, Molecular Biology or Biochemistry, and three years of recent, related experience in a research and or clinical laboratory.
• Proven expertise with Python, R, and/or other similar high-level languages.
• Functional knowledge of distributed version control systems, such as Git.
• Demonstrated experience with analysis of next generation sequencing data with an understanding of standards and guidelines for validating clinical bioinformatics analysis pipelines using these technologies.
• Comfortable working in a Linux environment, including experience with shell scripting and common command-line tools.
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
• Demonstrated ability to efficiently organize work assignments and establish priorities to meet set milestones.
• Demonstrated ability to write technical documents including validations and procedure manuals.
• Experience with bioinformatic workflow managers and database development would be considered an asset.

Benefits:

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• Enjoy a comprehensive benefits package, which includes statutory benefits - Canada Pension Plan, Employment Insurance and WorkSafe BC plus the BC Cancer group benefits plan which includes medical & dental extended health, and group life insurance coverage, and psychological health & safety programs and holistic wellness resources.
• Annual statutory holidays (13) with generous vacation entitlement and accruement.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: 

Temporary Full-Time, 7.5 hrs. per day

Hybrid

Salary Range: 

$67,861 - $97,550 p.a.

The starting salary for this position would be determined with consideration of the successful candidate’s relevant education and experience, and would be in alignment with the provincial compensation reference plan. 

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: RP_R00008_CCGI_2026_01_14 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

COVID-19 vaccines protect against infection from severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) that causes COVID-19. 

The COVID-19 vaccine has been added to the list of high-priority immunizations recommended for health-care workers. Health care workers should ensure they are up-to-date on all routine immunizations. 

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

 

Academic

 

Job Category

Faculty Non Bargaining

Job Title

Postdoctoral Research Fellow - Single Cell Genomics, drug resistance in cancer

 

Department

Aparicio Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine (Samuel Aparicio)

 

JOB DESCRIPTION:

Post-doctoral Fellow (PDF) Single Cell Genomics, drug resistance in cancer We are seeking a highly-motivated post-doctoral fellow (PDF) with strong leadership ability and expertise in single cell genomics and transcriptomics, and a strong background in molecular biology. The successful applicant will work full-time under the supervision of Dr. Samuel Aparicio on an exciting project decoding the role of epigenomic and genomic drug resistance. The position start date is flexible.

JOB SUMMARY:
The Aparicio lab is developing new single cell genome and transcriptome methods for tracking clonal trajectories at single cell level in patient tissues and patient-derived xenografts (PDX). The lab is highly multidisciplinary and highly productive (Laks et al, Cell 2019, Salehi et al Nature 2021, Funnell et al Nature 2022) and is well funded for single cell analysis of genomes and transcriptomes in cancer. The Aparicio lab is developing new single cell genome and transcriptome methods for tracking clonal trajectories at single cell level in patients and patient-derived xenografts. The project involves collaborating on an exciting project mapping clonal dynamics in human cancers under drug treatment with new single cell methods. The post holder will also have the opportunity to interact as part of the international Welcome LEAP Delta Tissue project and an exciting new program in the biology of epithelium from high risk carriers of BRCA1/BRCA2 mutations. These projects are bringing new measurement methods and computational techniques to the 3D reconstruction of tumours, and mapping drug sensitivity and drug combinations using sgRNA/CRISPR methods in vivo. The program works closely with UBC departments of statistics and computer science and the New York Genome Center NY, on the development of new models for single cell data and cancer evolution. Some experience with bioinformatics approaches to biological data and familiarity with handling of genomics data will be an advantage.

ORGANIZATIONAL STATUS:

Aparicio Lab is located in the department of Molecular Oncology at BC Cancer Research Center in Vancouver, British Columbia, Canada. The candidate will report directly to Dr. Samuel Aparicio, and will play a senior leadership role in the laboratory.

The Department of Pathology and Laboratory Medicine at UBC is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients.  The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence. 

WORK PERFORMED:
● Provide leadership, strategic direction, and translational research pertaining to single cell genomics and transcriptomics, and CRISPR methods.
● Design and implement research plan to investigate the clonal dynamics in human cancer through single cell methods.
● Design and conduct animal experiments.
● Conduct in vivo testing or characterization of drugs, small molecules, knockouts or antibodies in relevant PDX animal models.
● Foster research collaborations and work jointly with academic, clinical, industry, and other partners.
● Scientifically document lab experiments, data analysis, interpretations.
● Write manuscripts, present results at internal and external meetings.
● Identify funding opportunities and if required write or assist with grant proposals
● Lead and mentor junior trainees/students in the laboratory

CONSEQUENCE OF ERROR:
This is a senior research position that plays a critical role in the development of this novel field. PDF is accountable for the quality and integrity of the research and data, including analyses and interpretation, as well as the effective and efficient management of research projects and deliverables. This position requires innovation, strategic planning, and adaptability. Incorrect decisions or actions may damage the reputation of the laboratory, lead to loss of credibility in this field, and be financially costly.

SUPERVISION RECEIVED:

The PDF will work with a high degree of independence and set priorities under broad directives from Dr. Aparicio. The PDF will be expected to provide direction and mentoring in the laboratory under the supervision of Dr. Aparicio. This position will also provide the candidate with a high level of exposure to single cell genomics and translational research, as well as, providing opportunities to work collaboratively with industry partners and other researchers globally.

SUPERVISION GIVEN:

The PDF will be expected to provide mentorship and guidance to undergraduate, graduate students and other research members as required.

QUALIFICATION:
● Ph.D. in biology, cell biology, molecular biology, biochemistry, genetics, genomics, or similar discipline.
● The candidate should have a solid scientific and technical background with excellent written/oral communication, interpersonal and organizational skills.
● Preference will be given to candidates with a proven track record with a minimum of 2-3 first author publications in reputable journals.
● Proficiency in cell biology, molecular biology, histology, genetics, genomics, next-generation sequencing and biochemistry techniques.
● Demonstrate the ability to work in a highly interdisciplinary environment.
● Experience with cancer research.
● Expertise and hands-on experience in animal studies, including all aspects of design, handling, breeding, tissue collection, histology, and analyses are essential.
● Familiarity with testing/characterization of small molecule or drug in vivo is preferred.
● Previous biochemical/cell biology and molecular biology experience with single cell genomics / transcriptomics, next generation sequencing, drugs screen and PDX modeling is an asset.
● Experience with statistical analyses and scientific writing. Previous experience with grant writing is an asset.
● Experience with bioinformatics approaches to biological data and familiarity with handling of genomics data is an asset.
● Applicants with experience and a strong track record with large drug target screening, single cell methods, and PDX mouse models are especially encouraged to apply.

How to Apply:

Exceptional candidates should submit a cover letter outlining your research interests and fit with the laboratory's research, curriculum vitae, and the names of three referees willing to provide letters of reference.

Due to the number of resumes we receive, we are unable to confirm receipt of submissions over the phone, or provide the status of the competition. Only shortlisted candidates will be contacted.

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

UBC hires on the basis of merit and is committed to employment equity. All qualified persons are encouraged to apply.

Equity and diversity are essential to academic excellence.  An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged.  We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, and/or Indigenous person.

JOB DESCRIPTION:

Post-doctoral Fellow (PDF) G-quadruplex biology and therapeutics We are seeking a highly-motivated post-doctoral fellow (PDF) with strong leadership ability and expertise in molecular biology, single cell genomics and transcriptomics, and a background in DNA drug target biology in cancer. The successful applicant will work full-time under the supervision of Dr. Samuel Aparicio. The position start date is flexible.

JOB SUMMARY:

A postdoctoral/research fellow position is available, working on an exciting international project to define additional mechanisms and target engagement of G4 ligands in cancer genomes, utilizing single cell sequencing and chemical biology methods. The Aparicio lab is developing small molecule ligands of G-quadruplex structures in DNA as a therapeutic, based on recent success from the lab demonstrating for the first time clinical proof of principle (Hilton et al, Nat. Comms 2022) for a G4 binder. The Aparicio lab is multidisciplinary environment, highly productive (Laks et al, Cell 2019, Salehi et al Nature 2021, Funnell et al Nature 2022, aparicio.molonc.ca for projects and papers) and is well funded for single cell analysis of genomes and transcriptomes in cancer. The labs has created and practices methods for sequencing single genomes, defining epigenetic states in single cells and mapping gene fitness in vivo (Eirew et al, Nat. Comms 2022). The post holder will also have the opportunity to interact as part of the international Welcome LEAP Delta Tissue project and an exciting new program in the biology of epithelium from high risk carriers of BRCA1/BRCA2 mutations. The program works closely with UBC departments of statistics and computer science and the New York Genome Center NY, on the development of new models for single cell data and cancer evolution. Some experience with bioinformatics approaches to biological data and familiarity with handling of genomics data will be an advantage, beyond core experience of molecular biology and drug target biology in cancer.

ORGANIZATIONAL STATUS:

Aparicio Lab is located in the department of Molecular Oncology at BC Cancer Research Center in Vancouver, British Columbia, Canada. The candidate will report directly to Dr. Samuel Aparicio, and will play a senior leadership role in the laboratory.

The Department of Pathology and Laboratory Medicine at UBC is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients.  The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence. 

WORK PERFORMED:
● Provide leadership, strategic direction, and translational research pertaining to single cell genomics and transcriptomics, and CRISPR methods.
● Design and implement research plan to investigate the clonal dynamics in human cancer through single cell methods.
● Design and conduct animal experiments.
● Conduct in vivo testing or characterization of drugs, small molecules, knockouts or antibodies in relevant PDX animal models.
● Foster research collaborations and work jointly with academic, clinical, industry, and other partners.
● Scientifically document lab experiments, data analysis, interpretations.
● Write manuscripts, present results at internal and external meetings.
● Identify funding opportunities and if required write or assist with grant proposals
● Lead and mentor junior trainees/students in the laboratory

CONSEQUENCE OF ERROR:
This is a senior research position that plays a critical role in the development of this novel field. PDF is accountable for the quality and integrity of the research and data, including analyses and interpretation, as well as the effective and efficient management of research projects and deliverables. This position
requires innovation, strategic planning, and adaptability. Incorrect decisions or actions may damage the reputation of the laboratory, lead to loss of credibility in this field, and be financially costly.

SUPERVISION RECEIVED:

The PDF will work with a high degree of independence and set priorities under broad directives from Dr. Aparicio. The PDF will be expected to provide direction and mentoring in the laboratory under the supervision of Dr. Aparicio. This position will also provide the candidate with a high level of exposure to single cell genomics and translational research, as well as, providing opportunities to work collaboratively with industry partners and other researchers globally.

SUPERVISION GIVEN:

The PDF will be expected to provide mentorship and guidance to undergraduate, graduate students and other research members as required.

QUALIFICATIONS:
● Ph.D. in biology, cell biology, molecular biology, biochemistry, genetics, genomics, or similar discipline.
● The candidate should have a solid scientific and technical background with excellent written/oral communication, interpersonal and organizational skills.
● Preference will be given to candidates with a proven track record with a minimum of 2-3 first author publications in reputable journals.
● Proficiency in cell biology, molecular biology, histology, genetics, genomics, next-generation sequencing and biochemistry techniques.
● Demonstrate the ability to work in a highly interdisciplinary environment.
● Experience with cancer research.
● Expertise and hands-on experience in animal studies, including all aspects of design, handling, breeding, tissue collection, histology, and analyses are essential.
● Familiarity with testing/characterization of small molecule or drug in vivo is preferred.
● Previous biochemical/cell biology and molecular biology experience with single cell genomics / transcriptomics, next generation sequencing, drugs screen and PDX modeling is an asset.
● Experience with statistical analyses and scientific writing. Previous experience with grant writing is an asset.
● Experience with bioinformatics approaches to biological data and familiarity with handling of genomics data is an asset.
● Applicants with experience and a strong track record with large drug target screening, single cell methods, and PDX mouse models are especially encouraged to apply.

How to Apply:

Exceptional candidates should submit a cover letter outlining your research interests and fit with the laboratory's research, curriculum vitae, and the names of three referees willing to provide letters of reference.

Due to the number of resumes we receive, we are unable to confirm receipt of submissions over the phone, or provide the status of the competition. Only shortlisted candidates will be contacted.

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

UBC hires on the basis of merit and is committed to employment equity. All qualified persons are encouraged to apply.

Equity and diversity are essential to academic excellence.  An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged.  We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, and/or Indigenous person.

We are currently looking for a Postdoctoral Fellow to join Dr. Andrew Roth’s and Dr. Adi Steif’s computational cancer genomics research groups at the BC Cancer Research Institute (BCCRI).

The current position is for a candidate with experience developing and applying computational methods to analyze high throughput biological data. The successful applicant will be part of an exceptional multidisciplinary team developing and applying single cell multiomic methods to study evolution and disease transformation risk in follicular lymphoma (FL). Funded by a multi-year Terry Fox New Frontiers Program Project Grant, the project is a close collaboration with clinicians, molecular biologists and bioinformatic scientists. The candidate will have the opportunity to work with a unique and complex dataset which includes single cell DNA, RNA and epigenetic data.

This is an opportunity to work with highly motivated colleagues in a creative and dynamic environment. By joining the Roth and Steif labs at the BCCRI, you will develop close relationships with world-renown specialists in genomics and bioinformatics and have access to robust computational and sequencing technology facilities, all while living in one of the most beautiful, diverse and eclectic cities in the world.

We offer a competitive salary, excellent benefits and significant career development opportunities

What you’ll do

Working in a multidisciplinary team, the postdoctoral fellow will develop and apply scalable analytical workflows for multiomic data integration and biological interpretation. The appointment is for one year in the first instance, with potential for renewal. Responsibilities include:

• Regularly review the scientific literature
• Contribute to experimental design and planning
• Data preprocessing and quality control
• Data analysis, visualization, and biological interpretation
• Develop and maintain well-documented code
• Regularly update Drs. Roth and Steif as well as key collaborators on the status of projects
• Participate in and present research updates at lab meetings, team meetings and conferences
• Contribute to scientific writing, including the preparation of research manuscripts and grant applications
• May be involved in recruitment, management, and supervision of trainees

What you bring

• A PhD in bioinformatics, computer science, statistics or related discipline
• At least 2 years of research experience in bioinformatics, with a record of first-author publication
• Experience in genomics and high-throughput sequencing data analysis
• Experience in cancer research is an asset
• Programming fluency in Python or R
• Experience working in a Unix/Linux computing environment

You have:

• Critical thinking and attention to detail
• Excellent verbal, written and interpersonal communication skills
• Ability to work independently and in a collaborative interdisciplinary team
• A strong work ethic, with demonstrated ability to manage time and prioritize to meet deadlines
• Commitment to upholding the shared responsibility of creating lasting and meaningful reconciliation in Canada as per TRC (2015) and BC's Declaration on the Rights of Indigenous Peoples Act (2019).
• Knowledge of social, economic, political and historical realities impacting indigenous communities and familiarity with Indigenous Cultural Safety and anti-racism and accompanying reports (BC DRIPA, TRC, etc.).

What we bring

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

Job Type: Temporary, Casual 
Location: 675 West 10th Avenue, Vancouver BC, V5Z 1G1
Hours of Work: Monday to Friday; 0830-1630
 

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

 

How to Apply

Applicants should submit: a CV; a one-page cover letter explaining how your research experience, interests and career goals align with the position; and the names and contact details of 3 references. 

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

 

What we do

About the GSC:

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The Genome Sciences Centre (GSC) is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics and bioinformatics pursuing novel treatment strategies for cancer and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research.

The GSC is part of BC Cancer Research Institute and the Provincial Health Services Authority (PHSA).

BC Cancer provides comprehensive cancer control for the people of British Columbia.

BC Cancer is part of the Provincial Health Services Authority (PHSA).

(PHSA) plans, manages and evaluates specialized health services with the BC health authorities to provide equitable and cost-effective health care for people throughout the province. Our values reflect our commitment to excellence and include: Respect people – Be compassionate – Dare to innovate – Cultivate partnerships – Serve with purpose.

Learn more about PHSA and our programs: jobs.phsa.ca/programs-and-services

PHSA is committed to employment equity, encouraging all qualified individuals to apply. We recognize that our ability to provide the best care for our diverse patient populations relies on a rich diversity of skills, knowledge, background and experience, and value a safe, inclusive and welcoming environment.

Reconciliation is an ongoing process and a shared responsibility for all of us. The BC Governments’ unanimous passage of the Declaration on the Rights of Indigenous Peoples Act was a significant step forward in this journey—one that all health authorities are expected to support as we work in cooperation with Indigenous Peoples to establish a clear and sustainable path to lasting reconciliation. True reconciliation will take time and ongoing commitment to work with Indigenous Peoples as they move toward self-determination. Guiding these efforts Crown agencies must remain focused on creating opportunities that implement the Truth and Reconciliation Commission Mandate.

Job Summary
Researchers in the Department of Molecular Oncology at BC Cancer Research Institute use the latest technologies to rapidly identify genes that are involved in the development of cancer. We are seeking a highly-motivated, organized, driven individual with an interest or past experience with working with research animals in an academic setting. This entry level position will provide the successful candidate with an opportunity to work and learn within an academic research environment where continual training and learning is greatly encouraged. The core focus of this position will be handling and working with research animals, as well as, conducting research experiments on animals; hands-on training will be provided to the successful candidate. This animal tech position will be involved with performing research in drug pharmacology directed at human tumours, with assays in immunodeficient mice (xenotransplants).

Organizational Status
The successful applicant will report to the Principal Investigator or his/her delegate and may assist in overseeing technical work of students and trainees.

Work Performed

• Perform and/or oversee animal procedures involving immunization, oral gavage, injections, tumour inoculation, tumour volume measurements, blood and tissue collection, surgical procedures, necropsy, and post-operative care.
• Assist in the daily care of transgenic animals and maintains colonies of human tumour bearing immunodeficient animals.
• Daily health monitoring and care of laboratory animals.
• Plan and perform animal experiments utilizing complex procedures and/or techniques.
• Be able to recognize and resolve behavioral and/or housing issues; may provide technical instructions and training for other staff and/or trainees
• Process tissue samples and carry out primary cell isolation as instructed.
• Carry out laboratory techniques following standard operating protocols ages, tables, graphs and charts.
• Maintain both laboratory and laboratory records of both animal data and experimental data; when required to summarize results in research reports and lab presentations.
• Perform other related duties as assigned.
• On a rotation basis, must be available for emergency calls 24/7 and respond appropriately.

Minimum Qualifications
Completion of a relevant technical program or a university degree in a relevant discipline and a minimum three years of related experience or an equivalent combination of education and experience.

• Willingness to respect diverse perspectives, including perspectives in conflict with one’s own
• Demonstrates a commitment to enhancing one’s own awareness, knowledge, and skills related to equity, diversity, and inclusion

Preferred Qualifications

• Postgraduate degree in Science is preferred.
• CALAS certification (e.g. RLAT) is an asset.
• Minimum of 3 years related experience or the equivalent combination of education and experience.
• Experience with cell culture and aseptic technique preferred, involving both isolation and maintenance of rodent primary cultures and cell lines.
• Experience in the use and handling of hazardous materials such as biological agents and cytotoxic drugs is essential.
• Experience in the monitoring and management of human tumour bearing animals.
• A working knowledge of the CCAC guidelines and compassion and sensitivity for animals.
• Strong interpersonal skills and the ability to interact positively and productively with other team members are essential.
• Ability to communicate effectively both orally and in writing.
• The successful candidate must be well-organized, conscientious, understand the importance of detail, and be able to multi-task and prioritize duties effectively.

Job Summary:

The candidate would work within a dynamic and vibrant lab with a proven track record of outstanding achievements and contributions in breast oncology research. This position allows the candidate to contribute bold and innovative research that can be translated to new understanding in the evolutionary processes that drive cancers.

This position's primary focus in the lab will be to lead and to participate in projects based on candidate's desire concentrated on investigating genetics of breast oncology, cancer evolutionary, and development of novel therapeutics. Using the wide network of connections and collaborations of the principal investigator, and extensive biomedical resources at the institution, candidates will be able to build on the existing research of the lab to quickly start up their own research projects.

The position will provide a unique opportunity for mentoring trainees, supervising analysts and interacting with industry. This is an excellent platform to receive outstanding training to gain the important skills for a successful medical research career in academia or industry.

This funded position with the University of British Columbia, at the BC Cancer Research Centre allows the candidate to flourish under the guidance of an experienced mentor.

Organizational Status:

The Postdoctoral Fellow will play a leadership role in the Aparicio lab, and will be reporting directly to Dr. Samuel Aparicio who is the primary investigator of the laboratory. More information on the lab, please visit https://aparicio.molonc.ca

The Department of Pathology and Laboratory Medicine at UBC is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients.  The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence.

Work Performed:

• Management and supervision of trainees;
• May be involved in recruitment and training of trainees;
• Performing regular reviews of the relevant literature;
• Planning and designing of experiments;
• Analyzing, interpreting and compiling data in study reports, presenting results, and participating in the preparation of scientific manuscripts and grant application packages;
• Updating Dr. Aparicio and the group on the status of projects during lab meetings, in email correspondence and phone conferences;
• Managing projects with key academic and industry partners.

Minimum Qualifications:

• PhD degree in the computer science, bioinformatics or equivalent
• At least 4 years experience in bioinformatics research
• Experience in genomics and next-generation sequencing
• Extensive knowledge of cellular and molecular biology, biochemistry and genetics
• Experience with cancer research a plus
• Proven ability to multi-task in a deadline oriented environment with minimal supervision
• Effective oral and written communication, analytical, and interpersonal skills
• Excellent organizational skill and ability to learn new skills quickly
• Ability to work independently and within a team environment.
• Accuracy and attention to detail required
• Candidates should demonstrate the ability to work in a highly interdisciplinary environment.

Supervision Received:

• Works independently under direction of PI, Dr. Samuel Aparicio
• Opportunities to work collaboratively with Industry partners and other researchers at UBC and globally

Supervision Given:

• Assists and oversees research assistants and students as required
• Assists and provides guidelines to other research members, as required

How to Apply:

Exceptional candidates should submit a cover letter outlining your research interests and fit with the laboratory's research, curriculum vitae, and the names of three referees willing to provide letters of reference.

Due to the number of resumes we receive, we are unable to confirm receipt of submissions over the phone, or provide the status of the competition. Only shortlisted candidates will be contacted.

This position is located within a health-care facility. Therefore, this positions requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

Equity and diversity are essential to academic excellence.  An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged.  We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.

All qualified candidates are encouraged to apply; however Canadians and permanent residents will be given priority.

Email to apply: careersmolonc@bccrc.ca

Please put Bioinformatics PDF in the subject line.

We are seeking a highly-motivated, organized, driven individual with an interest or past experience with working with research animal in an academic setting. This entry level position will provide candidate with an opportunity to work and learning within an academic research environment where continual training and learning is greatly encouraged as part of the lab culture. The core focus of this position will be handling and working with research animal, as well as, conducting research experiments on animals; hands-on training will be provided to the successful candidate.

You will become an integral part of the animal research team, providing technical support on animal research for multiple core projects within the lab. 

What you’ll do

• Perform a variety of established technical procedures according to written protocols.
• Perform experiments by following established laboratory procedures according to written protocols.
• Record results, including computer data entry
• Provide input regarding modification of procedures as requested by the Department Head, Principal Investigator, or designate.
• Maintain and store cell lines and primary cultures.
• Maintain and store test materials and products.
• Maintain inventory of laboratory supplies and equipment.
• May demonstrate work methods or procedures to less experienced assistants as designated.

What you bring

• A level of education, training, and experience equivalent to graduation from a recognized Bachelor’s program in an appropriate discipline (e.g. Bachelor of Science); .
• Two (2) years of recent related experience in a research laboratory.

You have:

• Commitment to upholding the shared responsibility of creating lasting and meaningful reconciliation in Canada as per TRC (2015) and BC's Declaration on the Rights of Indigenous Peoples Act (2019).
• Knowledge of social, economic, political and historical realities impacting indigenous communities and familiarity with Indigenous Cultural Safety and anti-racism and accompanying reports (BC DRIPA, TRC, etc.).

What we bring 

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in the future. That’s why we’re focused on your care too – offering health, wellness, development programs to support you – at work and at home.

• Join one of BC’s largest employers with province-wide programs, services and operations – offering vast opportunities for growth, development, and recognition programs that honour the commitment and contribution of all employees.
• Access to professional development opportunities through our in-house training programs, including +2,000 courses, such as our San’yas Indigenous Cultural Safety Training course, or Core Linx for Leadership roles.
• Enjoy a comprehensive benefits package, including municipal pension plan, and psychological health & safety programs and holistic wellness resources.
• Annual statutory holidays (13) with generous vacation entitlement and accruement.
• PHSA is a remote work friendly employer, welcoming flexible work options to support our people (eligibility may vary, depending on position).
• Access to WorkPerks, a premium discount program offering a wide range of local and national discounts on electronics, entertainment, dining, travel, wellness, apparel, and more.

One postdoctoral fellow position is immediately available at the BC Cancer Research Institute in Vancouver, Canada for the development of novel radiopharmaceuticals for cancer imaging and radiotherapy. The postdoctoral fellow will conduct research in the design and synthesis of radioligands targeting biomarkers overexpressed in cancers. Research activities will involve the production and isolation of radioisotopes, peptide and multi-step organic synthesis, and radiolabeling small molecules, peptides and antibodies with various imaging and radiotherapeutic isotopes (F-18, Ga-68, Zr-89, Tc-99m, I-123, In-111, Lu-177, Ac-225 …).

Qualified candidates should have a PhD degree in radiochemistry, organic or medicinal chemistry with experience in peptide or multi-step organic synthesis. Experience with HPLC, micro-scale reactions, and radiochemistry is strongly desirable but not required. The ability to perform research in a collaborative environment is required including excellent oral and written communication skills. This joint position between BC Cancer Research Institute and University of British Columbia (UBC) is for a period of two years with the possibility of renewal.

Interested candidates should send a letter of application, curriculum vitae, and names of three references to :
Dr. Kuo-Shyan Lin
Senior Scientist, BC Cancer Research Centre
Associate Professor, University of British Columbia
E-mail: klin@bccrc.ca

Review of applications will begin immediately and will continue until the position is filled.

JOB SUMMARY

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position. These positions supervise designated staff by scheduling and assigning work, and assist in daily animal care operations by leading various health monitoring and colony management programs, trouble-shooting minor issues and performing other administrative tasks. These positions also maintain the daily care of laboratory mice and perform various surgical procedures and laboratory techniques.

                                               

DUTIES/ACCOUNTABILITIES

• Develops, implements, reviews and updates animal care standard operating procedures for assigned area.

• Leads various animal care programs such as health monitoring and colony management.

• Maintains current knowledge of, and ensures compliance with, animal care regulations.

• Supervises designated staff by scheduling and assigning work, providing orientation and training and monitoring performance.

• Maintains daily care of laboratory mice including maintaining adequate food and water levels and observing mice for general health conditions.

• Performs surgeries and techniques including blood collection, surgical implantations, tumour implantation, injection of solutions, collection of tissues and organs and embryo manipulations, and cryopreservation.

• Performs laboratory techniques such as media preparation, cell culture and hormone preparation, and polymerase chain reaction analysis as required.

• Leads training programs, prepares and gives presentations and orients and trains staff and animal users on proper animal care theory, protocols, techniques and procedures.

• Changes and cleans animal cages, bottles and racks.

• Performs general cleaning of animal facilities including disinfecting equipment, walls, floors, rooms, etc.

• Performs census duties such as counting cages and reporting cage numbers.

• Receives and processes laboratory animal care supplies.

                                               

QUALIFICATIONS

A level of education, training, and experience equivalent to graduation from a recognized program in Animal Health or Veterinary Technology, or a Bachelor’s program in an appropriate discipline (e.g. Animal Science); plus five (5) years of recent related experience in a research laboratory, including two (2) years in a supervisory capacity.