New enzymatic platform harnesses DNA’s programmability towards the creation of custom radiopharmaceuticals

Researchers at BC Cancer Research Institute (BCCRI) and UBC Chemistry have created a new way to build radioactive DNA molecules that could help reimagine how radiolabeled drugs are built. Using enzymes that normally copy genetic material, scientists programmed synthetic DNA to carry cancer‑fighting isotopes in precise patterns, opening the door to developing drugs that could both image tumors and destroy them with the same molecule. 

New research identifies a promising target in multiple fusion-driven cancers

A new multinational study led by Dr. Poul Sorensen, distinguished scientist at BC Cancer Research Institute, professor in the UBC Faculty of Medicine and holder of the Johal Chair in Childhood Cancer Research, has been published in Cancer Discovery, a leading journal of the American Association for Cancer Research.

Dr. Samuel Aparicio, co-senior author on Nature Aging paper linking breast tissue aging to cancer risk

Dr. Samuel Aparicio, distinguished scientist at the BC Cancer Research Institute and professor at the University of British Columbia, is co-senior author on a recent paper providing the most detailed map to date of how breast tissue changes over a woman’s lifetime, revealing the role of menopause in cancer susceptibility. The study was co-led with scientists at the University of Cambridge.

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