Liver cancer is a serious and often late-diagnosed disease, with hepatocellular carcinoma (HCC) being the most prevalent form, accounting for 90% of cases. HCC typically develops in individuals who have experienced chronic liver damage. Over time, the liver’s natural regenerative processes can result in scarring, inflammation, and ultimately, the development of cancer.

Despite its substantial global impact, liver cancer remains underfunded and insufficiently studied. The LivBC program is committed to bridging this gap by identifying biomarkers linked to the onset and progression of liver cancer, which will contribute to earlier detection and more effective treatment strategies.
 

Liver Cancer Risk Factors

Chronic Disease

Chronic conditions such as hepatitis B or C viral infections, liver cirrhosis, and non-alcoholic steatohepatitis (NASH) can cause long-term liver damage, inflammation, and scarring. Over time, these issues greatly increase the risk of liver cancer. Early detection, lifestyle changes, and proper medical management are key to slowing disease progression and improving patient outcomes.

Lifestyle Factors

Unhealthy habits like smoking, excessive alcohol consumption, and obesity can severely impact liver health, leading to chronic damage and increasing the risk of liver cancer. Maintaining a healthy diet, exercising regularly, and avoiding harmful substances can help protect the liver and lower cancer risk.

Genetic Predisposition

A family history of liver cancer can increase an individual’s risk of developing the disease. In addition, certain rare genetic conditions that affect metabolism may further contribute to liver cancer susceptibility. Those with a family history should consult a healthcare professional to assess their risk and explore preventive strategies, including lifestyle modifications and regular screenings.

For more information on liver cancer, visit the BC Cancer (link), the Canadian Cancer Society (link) and the National Cancer Institute (link)
 

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