CCR has a number of strong core research programs directed to the reduction of incidence and mortality from cancer, sustainability of cancer care, and alleviating the burden of suffering from cancer.
The BC Oral Cancer Prevention Program (BC OCPP)
is a translational program whose goal is to integrate prevention, screening, early diagnosis and effective treatment of oral cancer and its precursor lesions into a province-wide seamless network. The program trains dentists and dental assistants to do oral screening, with referral of patients with suspicious lesions to biopsy. Patient lesions are assessed using an BC OCPP developed risk model to determine probability of progression or regression, and the patients are triaged into high or low oral cancer risk groups. High risk individuals can then be followed. The program (in conjunction with Cancer Imaging) has developed tools (VELscope; toluidine blue application; etc) for earlier clinical diagnosis, and better margin visualization of frank cancers. These advances should help surgeons and radiation oncologists materially reduce the frequency of recurrence or metastasis from oral cancer.
The aim is to translate research findings into practical care at a population level with a minimum of delay. BC OCPP has several provincial, national and international initiatives in place, including a joint Canada-India program to export our technology and procedures to India where oral cancer is one of that nation’s major malignancies.
The Canadian Centre for Applied Research in Cancer Control (ARCC)
is an innovative, pan-Canadian research centre specializing in health economics, services, policy and ethics applied to cancer control. As leaders of policy relevant research, education and knowledge translation, we aim to make improvements across the cancer control spectrum – from prevention, screening and diagnosis to treatment, rehabilitation, survivorship or palliative care.
ARCC is a partnership that was formalized in 2009 between the Canadian Cancer Society, the British Columbia Cancer Agency and Cancer Care Ontario. We are unique collaboration between researchers, clinicians and decision makers from the British Columbia Cancer Agency, Cancer Care Ontario, the University of British Columbia and the University of Toronto.
ARCC is dedicated to being a pan-Canadian centre. With initial funding from the Canadian Cancer Society, as we expand we will build partnerships with other provincial cancer agencies and Canadian universities to achieve national representation.
examines long-term sequelae resulting from a diagnosis of childhood cancer and its treatment, and health care relating to these late effects.This multi-study initiative is funded by a Canadian Cancer Society program project grant, with additional funding from CCS BC and Yukon Division, and has examined long-term health effects and educational attainment, health care utilization, and quality of follow-up care among disease survivors. The ultimate aim of this program is to elucidate the areas of concern and translate these findings into cost-effective policy and practice.
A similar program examining health and health care issues among breast cancer survivors is BC is funded by the Canadian Breast Cancer Foundation, BC and Yukon Division.
The Gene-Environment Interactions in Cancer (GENIC) Program
is the longest standing initiative within CCR. GENIC has completed (or has ongoing) a series of studies to examine the interaction between environmental risk factors and susceptibility genes for non-Hodgkin lymphoma, melanoma, and multiple myeloma, as well as breast, ovarian, and prostate cancers. An exciting new research platform under construction is the BC Generations Project (BCGP). BCGP has collected health information and biological samples from nearly 30,000 British Columbians as part of a national project to recruiting 250,000 Canadians. This observational cohort will be followed for up to 30 years for the development not only of cancer but of all chronic diseases. The data will be used by scientists across Canada to identify how environment, lifestyle and genetic susceptibility interact in the development of cancer.