Breast Cancer

Our research group develops computational methods for the analysis of high throughput cancer genomics data.  We use machine learning techniques to develop statistical models to infer genomic abnormalities from next generation sequencing data and high-density genotyping arrays.  Dr. Andrew Roth and Dr. Sohrab Shah work with Dr. David Huntsman and Dr. Sam Aparicio who lead ovarian cancer and breast cancer research respectively at BC Cancer, part of the Provincial Health Services Authority.

The team, led by Dr. François Bénard, has extensive experience in the pre-clinical development of radiotracers for PET/CT imaging, their translation to the clinic, and clinical trial design/execution. They have developed several new radiopharmaceuticals targeting tumour receptors, notably peptides and small molecule ligands. Dr. Bénard initiated the program that developed cyclotron production of 99mTc, now in clinical trials at multiple sites in Canada. A state-of-the-art cyclotron and molecular imaging facility was also established at BC Cancer.