Dr. Philipp Lange, Canada Research Chair in Translational Proteomics of Pediatric Malignancies and his team at The University of British Columbia (UBC) in Vancouver, Canada, seek an outstanding candidate with exceptional passion to advance precision oncology for children and the fundamental understanding of proteome modulation in childhood disorders.
The successful candidate will report directly to Dr. Philipp Lange, the principal investigator, and will work in a strongly collaborative and collegial fashion with cross-functional project team members to meet research goals and objectives.
The research associate will lead data analysis and reporting for multiple single case and cohort studies in the precision oncology BRAvE and PROFYLE initiatives as well as collaboration projects. In this role, they will perform statistically robust analysis and integration of molecular (proteomics, genomic, metabolomic) and phenotypic (clinical, immunophenotype, drug perturbation, …) data, write reports and engage with team members and collaborators to provide key input on experimental design, data interpretation and overall direction of the studies. The research associate will also have the opportunity to conduct experiments of their own to advance the studies.
The incumbent will represent the laboratory in national and international initiatives, lead collaborative projects, train graduate and undergraduate students, introduce new methodologies to the lab and make major contributions to grant proposals and manuscripts.
Consequence of Error:
The successful applicant is expected to exercise a considerable amount of judgment, responsibility, and initiative in determining work procedures and methods. He/she should carefully observe and evaluate their work. All works are subject to assessment by Dr. Lange. Consistent poor judgment decisions or errors can result in incorrect data interpretation and potential loss of funding.
The applicant is expected to work independently under the direction of Dr. Lange, who will be available to provide consultation on unusual problems and project developments.
Assist with training graduate students and junior lab staff; provide input on staff/co-op student selection and performance evaluation.
- PhD and Postdoctoral in cancer biology, immunology or related area
- Strong publication record
- Fluent in written and spoken English and demonstrated excellence in scientific writing
- Demonstrated exceptional analytical, communication and visualization skills
- Strong statistical foundation and expertise in R or python for data analysis
- Exceptional understanding of biological mechanisms and well read
- Expertise in CRISPER genome editing, mass spectrometry, cell surface and secretome characterization are assets but not required
Research Team & Environment: Located at the BC Children’s Hospital Research Institute (BCCHRI), the leading pediatric research center in Western Canada, you will be embedded in the highly innovative and interdisciplinary research environment spanning BC Children’s Hospital, UBC and BC Cancer Agency. Vancouver repeatedly ranks among the most livable places in the world and combines excellence in research with high quality of life. Excellent opportunities for personal and professional development are provided.
The incumbent will be part of a dynamic team of experimental and computational scientists and embedded in the local BRAvE and national PROFYLE pediatric precision oncology initiatives, where they will work with basic scientists, pathologists, analysts and clinicians. They will work in the newly renovated digital-health offices with direct access to state-of-the-art compute infrastructure and software, as well as, cell and molecular biology facilities, mouse and chicken chorioallantoic membrane (CAM) modeling platforms, mass-spectrometry, next-generation sequencing, flow cytometry, imaging and compute infrastructure.
The Department of Pathology and Laboratory Medicine at UBC is a hybrid, academically intensive Department within the UBC Faculty of Medicine whose activities span a broad spectrum of teaching, research, and academic service, often performed in the milieu of clinical practice, and are ultimately devoted to improving the care, treatment, and well-being of patients. The Department offers academic degrees at the bachelor’s (Bachelor of Medical Laboratory Science (BMLSc)) and graduate (MSc, PhD) levels with the graduate program, one of the largest in the Faculty of Medicine, which has been recognized by UBC for its quality. The Department plays a major role in the MD undergraduate program and offers an accredited residency-training program. Faculty members participate across a spectrum of research from basic investigative to translational to clinical applied research and are recognized locally, nationally and internationally for their excellence.
How to apply:
Review of applications will begin May 1, 2022. The position will commence as soon as possible.
Please send a cover letter expressing your long-term research vision, career goals and fit for the position (detailing how you meet the requirements). PDF copies of your most impactful papers (max 3, submitted manuscripts OK) as well as your CV and contacts (full address, email and phone number) for three references to firstname.lastname@example.org. Please send your documents in one PDF file. Only shortlisted candidates will be contacted.
Salary will be commensurate with experience and full benefits will be provided. The term of the position may be extended pending successful review of performance and productivity and continued funding availability.