BC Cancer - Genome Sciences Centre

Our scientists are experts in genomics, bioinformatics and molecular biology technology development, collaborating on projects within Canada and around the world.

The Genome Sciences Centre is one of nine research departments and programs that operate as part of the BC Cancer Research Centre. BC Cancer, part of the Provincial Health Services Authority, provides a province-wide cancer control program for the residents of British Columbia. Additional support is provided by funds raised by the BC Cancer Foundation for cancer research.

A key element of the GSC is the genomics, proteomics and informatics platforms. The priority of the platforms is to develop innovative means to automate the sequencing process, develop cost-effective measures that will make such research financially viable, and utilize leading edge computing tools to collect, mine, analyze and disperse data collected at this and other genome facilities. To accomplish this, the platform fully exploits the most recent technological advances in genomics, proteomics, and high performance computing, within a state-of-the-art facility designed to generate and extract information from complex samples and valuable sample collections, for the benefit and use of the wider scientific community. 

Cancer

  • We are accredited through the College of American Pathologists (CAP), a rigorous standard recognized throughout North America for clinical applications, to perform clinical sequencing to detect cancer susceptibility mutations through capture panels and whole genome sequencing. 
  • Our Personalized OncoGenomics program is currently transferring this expertise into real-time treatment planning for BC patients with incurable cancers;
  • GSC researchers are asking important questions about hereditary cancers in the Lymphoma Families Study, the relationship between microorganisms and colorectal cancer tumours, working to develop new drug treatments for aggressive prostate cancer, playing key roles in international cancer research collaborations such as The Cancer Genome Atlas (TCGA) and more.  

Other health-related projects: 

       Healthy Agingintellectual disabilityprenatal testing, epigenomics research (across Canada and Internationally)

Infectious disease

       We were involved in the rapid sequencing of the SARS Coronavirus, sequencing and genome analysis of the avian flu (H7N3)Tuberculosis outbreak tracking

Economically and environmentally important organisms

       Including cattlesalmonpoplar and spruce treesmountain pine beetleamphibian sentinel species,  and wine grapes