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 Terry Fox Laboratory 
Terry Fox Laboratory Publications

Publications in refereed journals for the Terry Fox Laboratory are shown below. You can download these listings, as well as a record of symposium proceedings, review articles, books, etc., as a Download this file Word File.

Peer-Reviewed Papers
Peer-Reviewed Papers

    2001

  1. Audet J, Miller CL, Rose-John S, Piret JM, Eaves CJ. Distinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells. Proc Natl Acad Sci U S A 98(4):1757-62. (2001).
     [View Abstract - PubMed 11172024]

  2. Brummendorf TH, Maciejewski JP, Mak J, Young NS, Lansdorp PM. Telomere length in leukocyte subpopulations of patients with aplastic anemia. Blood 97(4):895-900. (2001).
     [View Abstract - PubMed 11159514]

  3. Buske C, Feuring-Buske M, Antonchuk J, Rosten P, Hogge DE, Eaves CJ, Humphries RK. Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo. Blood 97(8):2286-92. (2001).
     [View Abstract - PubMed 11290589]

  4. Damen JE, Ware MD, Kalesnikoff J, Hughes MR, Krystal G. SHIP's C-terminus is essential for its hydrolysis of PIP3 and inhibition of mast cell degranulation. Blood 97(5):1343-51. (2001).
     [View Abstract - PubMed 11222379]

  5. Feuring-Buske M, Hogge DE. Hoechst 33342 efflux identifies a subpopulation of cytogenetically normal CD34(+)CD38(-) progenitor cells from patients with acute myeloid leukemia. Blood 97(12):3882-9. (2001).
     [View Abstract - PubMed 11389030]

  6. Glimm H, Eisterer W, Lee K, Cashman J, Holyoake TL, Nicolini F, Shultz LD, von Kalle C, Eaves CJ. Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-beta2 microglobulin-null mice. J Clin Invest 107(2):199-206. (2001).
     [View Abstract - PubMed 11160136]

  7. Hande MP, Balajee AS, Tchirkov A, Wynshaw-Boris A, Lansdorp PM. Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia. Hum Mol Genet 10(5):519-28. (2001).
     [View Abstract - PubMed 11181576]

  8. Holyoake TL, Jiang X, Jorgensen HG, Graham S, Alcorn MJ, Laird C, Eaves AC, Eaves CJ. Primitive quiescent leukemic cells from patients with chronic myeloid leukemia spontaneously initiate factor-independent growth in vitro in association with up-regulation of expression of interleukin-3. Blood 97(3):720-8. (2001).
     [View Abstract - PubMed 11157490]

  9. Kalesnikoff J, Huber M, Lam V, Damen JE, Zhang J, Siraganian RP, Krystal G. Monomeric IgE Stimulates Signaling Pathways in Mast Cells that Lead to Cytokine Production and Cell Survival. Immunity 14(6):801-11. (2001).
     [View Abstract - PubMed 11420049]

  10. Lohwasser S, Kubota A, Salcedo M, Lian RH, Takei F. The non-classical MHC class I molecule Qa-1(b) inhibits classical MHC class I-restricted cytotoxicity of cytotoxic T lymphocytes. Int Immunol 13(3):321-7. (2001).
     [View Abstract - PubMed 11222501]

  11. Mager DL, McQueen KL, Wee V, Freeman JD. Evolution of natural killer cell receptors. coexistence of functional Ly49 and KIR genes in baboons. Curr Biol 11(8):626-30. (2001).
     [View Abstract - PubMed 11369209]

  12. Malbec O, Schmitt C, Bruhns P, Krystal G, Fridman WH, Daeron M. The SH2 domain-containing Inositol 5-phosphatase SHIP1 mediates cell cycle arrest by Fc{gamma}RIIB. J Biol Chem . (2001).
     [View Abstract - PubMed 11359765]

  13. Martin CB, Mahon GM, Klinger MB, Kay RJ, Symons M, Der CJ, Whitehead IP. The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways. Oncogene 20(16):1953-63. (2001).
     [View Abstract - PubMed 11360179]

  14. McQueen KL, Wilhelm BT, Takei F, Mager DL. Functional analysis of 5' and 3' regions of the closely related Ly49c and j genes. Immunogenetics 52(3-4):212-23. (2001).
     [View Abstract - PubMed 11220623]

  15. Poon SS, Lansdorp PM. Measurements of telomere length on individual chromosomes by image cytometry. Methods Cell Biol 64:69-96. (2001).
     [View Abstract - PubMed 11070833]

  16. Rufer N, Brummendorf TH, Chapuis B, Helg C, Lansdorp PM, Roosnek E. Accelerated telomere shortening in hematological lineages is limited to the first year following stem cell transplantation. Blood 97(2):575-7. (2001).
     [View Abstract - PubMed 11154240]

  17. Taneja KL, Chavez EA, Coull J, Lansdorp PM. Multicolor fluorescence in situ hybridization with peptide nucleic acid probes for enumeration of specific chromosomes in human cells. Genes Chromosomes Cancer 30(1):57-63. (2001).
     [View Abstract - PubMed 11107176]

  18. Tilbrook PA, Palmer GA, Bittorf T, McCarthy DJ, Wright MJ, Sarna MK, Linnekin D, Cull VS, Williams JH, Ingley E, Schneider-Mergener J, Krystal G, Klinken SP. Maturation of erythroid cells and erythroleukemia development are affected by the kinase activity of Lyn. Cancer Res 61(6):2453-8. (2001).
     [View Abstract - PubMed 11289114]

  19. Wilhelm BT, McQueen KL, Freeman JD, Takei F, Mager DL. Comparative analysis of the promoter regions and transcriptional start sites of mouse Ly49 genes. Immunogenetics 53(3):215-24. (2001).
     [View Abstract - PubMed 11398966]

    20. 2000

  20. Abramovich C, Shen WF, Pineault N, Imren S, Montpetit B, Largman C, Humphries RK. Functional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNA. J Biol Chem 275(34):26172-7. (2000).
     [View Abstract - PubMed 10825160]

  21. Batliwalla FM, Rufer N, Lansdorp PM, Gregersen PK. Oligoclonal expansions in the CD8(+)CD28(-) T cells largely explain the shorter telomeres detected in this subset: analysis by flow FISH. Hum Immunol 61(10):951-8. (2000).
     [View Abstract - PubMed 11082508]

  22. Blair A, Sutherland HJ. Primitive acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo lack surface expression of c-kit (CD117). Exp Hematol 28(6):660-71. (2000).
     [View Abstract - PubMed 10880752]

  23. Brauweiler A, Tamir I, Dal Porto J, Benschop RJ, Helgason CD, Humphries RK, Freed JH, Cambier JC. Differential regulation of B cell development, activation, and death by the src homology 2 domain-containing 5' inositol phosphatase (SHIP). J Exp Med 191(9):1545-54. (2000).
     [View Abstract - PubMed 10790429]

  24. Brummendorf TH, Holyoake TL, Rufer N, Barnett MJ, Schulzer M, Eaves CJ, Eaves AC, Lansdorp PM. Prognostic implications of differences in telomere length between normal and malignant cells from patients with chronic myeloid leukemia measured by flow cytometry. Blood 95(6):1883-90. (2000).
     [View Abstract - PubMed 10706851]

  25. Buske C, Humphries RK. Homeobox genes in leukemogenesis. Int J Hematol 71(4):301-8. (2000).
     [View Abstract - PubMed 10905048]

  26. Cashman JD, Eaves CJ. High marrow seeding efficiency of human lymphomyeloid repopulating cells in irradiated NOD/SCID mice. Blood 96(12):3979-81. (2000).
     [View Abstract - PubMed 11090087]

  27. Croizat H, Ponchio L, Nicolini FE, Nagel RL, Eaves CJ. Primitive haematopoietic progenitors in the blood of patients with sickle cell disease appear to be endogenously mobilized. Br J Haematol 111(2):491-7. (2000).
     [View Abstract - PubMed 11122089]

  28. Feuring-Buske M, Frankel A, Gerhard B, Hogge D. Variable cytotoxicity of diphtheria toxin 388-granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells. Exp Hematol 28(12):1390-400. (2000).
     [View Abstract - PubMed 11146161]

  29. Frankel AE, McCubrey JA, Miller MS, Delatte S, Ramage J, Kiser M, Kucera GL, Alexander RL, Beran M, Tagge EP, Kreitman RJ, Hogge DE. Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias. Leukemia 14(4):576-85. (2000).
     [View Abstract - PubMed 10764142]

  30. Glimm H, Oh IH, Eaves CJ. Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G(2)/M transit and do not reenter G(0). Blood 96(13):4185-93. (2000).
     [View Abstract - PubMed 11110690]

  31. Guan Y, Hogge DE. Proliferative status of primitive hematopoietic progenitors from patients with acute myelogenous leukemia (AML). Leukemia 14(12):2135-41. (2000).
     [View Abstract - PubMed 11187903]

  32. Helgason CD, Kalberer CP, Damen JE, Chappel SM, Pineault N, Krystal G, Humphries RK. A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice. J Exp Med 191(5):781-94. (2000).
     [View Abstract - PubMed 10704460]

  33. Hennemann B, Chuo JY, Schley PD, Lambie K, Humphries RK, Eaves CJ. High-efficiency retroviral transduction of mammalian cells on positively charged surfaces. Hum Gene Ther 11(1):43-51. (2000).
     [View Abstract - PubMed 10646638]

  34. Hennemann B, Oh IH, Chuo JY, Kalberer CP, Schley PD, Rose-John S, Humphries RK, Eaves CJ. Efficient retrovirus-mediated gene transfer to transplantable human bone marrow cells in the absence of fibronectin. Blood 96(7):2432-9. (2000).
     [View Abstract - PubMed 11001895]

  35. Hogge DE, Lambie K, Sutherland HJ, Benny WB, Dalal B, Currie C, Barnett MJ, Eaves AC & Eaves CJ. Quantitation of primitive and lineage-committed progenitors in mobilized peripheral blood for prediction of platelet recovery post autologous transplant. Bone Marrow Transplant 25: 589-598. (2000).
     [View Abstract - PubMed 10734292]

  36. Hogge DE, Lambie K, Sutherland HJ, Benny WB, Dalal B, Currie C, Barnett MJ, Eaves AC, Eaves CJ. Quantitation of primitive and lineage-committed progenitors in mobilized peripheral blood for prediction of platelet recovery post autologous transplant. Bone Marrow Transplant 25(6):589-98. (2000).
     [View Abstract - PubMed 10734292]

  37. Huber M, Hughes MR, Krystal G. Thapsigargin-induced degranulation of mast cells is dependent on transient activation of phosphatidylinositol-3 kinase. J Immunol 165(1):124-33. (2000).
     [View Abstract - PubMed 10861044]

  38. Jiang X, Fujisaki T, Nicolini F, Berger M, Holyoake T, Eisterer W, Eaves C, Eaves A. Autonomous multi-lineage differentiation in vitro of primitive CD34+ cells from patients with chronic myeloid leukemia. Leukemia 14(6):1112-21. (2000).
     [View Abstract - PubMed 10865977]

  39. Kalberer CP, Pawliuk R, Imren S, Bachelot T, Takekoshi KJ, Fabry M, Eaves CJ, London IM, Humphries RK, Leboulch P. Preselection of retrovirally transduced bone marrow avoids subsequent stem cell gene silencing and age-dependent extinction of expression of human beta-globin in engrafted mice. Proc Natl Acad Sci U S A 97(10):5411-5. (2000).
     [View Abstract - PubMed 10792053]

  40. Krystal G. Lipid phosphatases in the immune system. Semin Immunol 12(4):397-403. (2000).
     [View Abstract - PubMed 10995586]

  41. Lansdorp PM. Repair of telomeric DNA prior to replicative senescence. Mech Ageing Dev 118(1-2):23-34. (2000).
     [View Abstract - PubMed 10989122]

  42. Lanza RP, Cibelli JB, Blackwell C, Cristofalo VJ, Francis MK, Baerlocher GM, Mak J, Schertzer M, Chavez EA, Sawyer N, Lansdorp PM, West MD. Extension of cell life-span and telomere length in animals cloned from senescent somatic cells. Science 288(5466):665-9. (2000).
     [View Abstract - PubMed 10784448]

  43. Liu Y, Snow BE, Hande MP, Baerlocher G, Kickhoefer VA, Yeung D, Wakeham A, Itie A, Siderovski DP, Lansdorp PM, Robinson MO, Harrington L. Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo. Mol Cell Biol 20(21):8178-84. (2000).
     [View Abstract - PubMed 11027287]

  44. Liu Y, Snow BE, Hande MP, Yeung D, Erdmann NJ, Wakeham A, Itie A, Siderovski DP, Lansdorp PM, Robinson MO, Harrington L. The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo. Curr Biol 10(22):1459-62. (2000).
     [View Abstract - PubMed 11102810]

  45. Lohwasser S, Wilhelm B, Mager DL, Takei F. The genomic organization of the mouse CD94 C-type lectin gene. Eur J Immunogenet 27(3):149-51. (2000).
     [View Abstract - PubMed 10940084]

  46. Lu L, Chappel MS, Humphries RK, Osmond DG. Regulation of cell survival during B lymphopoiesis: increased pre-B cell apoptosis in CD24-transgenic mouse bone marrow. Eur J Immunol 30(9):2686-91. (2000).
     [View Abstract - PubMed 11009103]

  47. Mager DL, Freeman JD. Novel mouse type D endogenous proviruses and ETn elements share long terminal repeat and internal sequences. J Virol 74(16):7221-9. (2000).
     [View Abstract - PubMed 10906176]

  48. Maguer-Satta V, Oostendorp R, Reid D, Eaves CJ. Evidence that ceramide mediates the ability of tumor necrosis factor to modulate primitive human hematopoietic cell fates. Blood 96(13):4118-23. (2000).
     [View Abstract - PubMed 11110682]

  49. Martens UM, Brass V, Engelhardt M, Glaser S, Waller CF, Lange W, Schmoor C, Poon SS, Landsdorp PM. Measurement of telomere length in haematopoietic cells using in situ hybridization techniques. Biochem Soc Trans 28(2):245-50. (2000).
     [View Abstract - PubMed 10816136]

  50. Martens UM, Chavez EA, Poon SS, Schmoor C, Lansdorp PM. Accumulation of short telomeres in human fibroblasts prior to replicative senescence. Exp Cell Res 256(1):291-9. (2000).
     [View Abstract - PubMed 10739676]

  51. Mathioudakis G, Storb R, McSweeney PA, Torok-Storb B, Lansdorp PM, Brummendorf TH, Gass MJ, Bryant EM, Storek J, Flowers ME, Gooley T, Nash RA. Polyclonal hematopoiesis with variable telomere shortening in human long-term allogeneic marrow graft recipients. Blood 96(12):3991-4. (2000).
     [View Abstract - PubMed 11090091]

  52. McCaul KG, Nevill TJ, Barnett MJ, Toze CL, Currie CJ, Sutherland HJ, Conneally EA, Shepherd JD, Nantel SH, Hogge DE, Klingemann HG. Treatment of steroid-resistant acute graft-versus-host disease with rabbit antithymocyte globulin. J Hematother Stem Cell Res 9(3):367-74. (2000).
     [View Abstract - PubMed 10894358]

  53. Metzler M, Helgason CD, Dragatsis I, Zhang T, Gan L, Pineault N, Zeitlin SO, Humphries RK, Hayden MR. Huntingtin is required for normal hematopoiesis. Hum Mol Genet 9(3):387-94. (2000).
     [View Abstract - PubMed 10655548]

  54. Niida H, Shinkai Y, Hande MP, Matsumoto T, Takehara S, Tachibana M, Oshimura M, Lansdorp PM, Furuichi Y. Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA. Mol Cell Biol 20(11):4115-27. (2000).
     [View Abstract - PubMed 10805753]

  55. Oh IH, Lau A, Eaves CJ. During ontogeny primitive (CD34(+)CD38(-)) hematopoietic cells show altered expression of a subset of genes associated with early cytokine and differentiation responses of their adult counterparts. Blood 96(13):4160-8. (2000).
     [View Abstract - PubMed 11110687]

  56. Oostendorp RA, Audet J, Eaves CJ. High-resolution tracking of cell division suggests similar cell cycle kinetics of hematopoietic stem cells stimulated in vitro and in vivo. Blood 95(3):855-62. (2000).
     [View Abstract - PubMed 10648396]

  57. Oostendorp RA, Ghaffari S, Eaves CJ. Kinetics of in vivo homing and recruitment into cycle of hematopoietic cells are organ-specific but CD44-independent. Bone Marrow Transplant 26(5):559-66. (2000).
     [View Abstract - PubMed 11019847]

  58. Pasquet JM, Quek L, Stevens C, Bobe R, Huber M, Duronio V, Krystal G, Watson SP. Phosphatidylinositol 3,4,5-trisphosphate regulates Ca(2+) entry via btk in platelets and megakaryocytes without increasing phospholipase C activity. EMBO J 19(12):2793-802. (2000).
     [View Abstract - PubMed 10856225]

  59. Reece DE, Brockington DA, Phillips GL, Barnett MJ, Klingemann HG, Nantel SH, Sutherland HJ, Shepherd JD. Prolonged survival after intensive therapy and purged ABMT in patients with multiple myeloma. Bone Marrow Transplant 26(6):621-6. (2000).
     [View Abstract - PubMed 11041567]

  60. Satterthwaite AB, Willis F, Kanchanastit P, Fruman D, Cantley LC, Helgason CD, Humphries RK, Lowell CA, Simon M, Leitges M, Tarakhovsky A, Tedder TF, Lesche R, Wu H, Witte ON. A sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase. Proc Natl Acad Sci U S A 97(12):6687-92. (2000).
     [View Abstract - PubMed 10829070]

  61. Tamir I, Stolpa JC, Helgason CD, Nakamura K, Bruhns P, Daeron M & Cambier JC. The RasGAP-binding protein-p62dok is a mediator of inhibitory FcgRIIB signals in B cells. Immunity 12: 347-358. (2000).

  62. Toze CL, Shepherd JD, Connors JM, Voss NJ, Gascoyne RD, Hogge DE, Klingemann H-G, Nantel SH, Nevill TJ, Phillips GL, Reece DE, Sutherland HJ & Barnett MJ. Allogeneic bone marrow transplantation for low-grade lymphoma and chronic lymphocytic leukemia. Bone Marrow Transplant 25: 605-612. (2000).
     [View Abstract - PubMed 10734294]

  63. Toze CL, Shepherd JD, Connors JM, Voss NJ, Gascoyne RD, Hogge DE, Klingemann HG, Nantel SH, Nevill TJ, Phillips GL, Reece DE, Sutherland HJ, Conneally EA, Barnett MJ. Allografting for indolent lymphoid neoplasms. Ann Oncol 11 Suppl 1:59-61. (2000).
     [View Abstract - PubMed 10707781]

  64. Wai DH, Knezevich SR, Lucas T, Jansen B, Kay RJ, Sorensen PH. The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells. Oncogene 19(7):906-15. (2000).
     [View Abstract - PubMed 10702799]

  65. Williams NS, Kubota A, Bennett M, Kumar V, Takei F. Clonal analysis of NK cell development from bone marrow progenitors in vitro: orderly acquisition of receptor gene expression. Eur J Immunol 30(7):2074-82. (2000).
     [View Abstract - PubMed 10940897]

  66. Zandstra PW, Lauffenburger DA, Eaves CJ. A ligand-receptor signaling threshold model of stem cell differentiation control: a biologically conserved mechanism applicable to hematopoiesis. Blood 96(4):1215-22. (2000).
     [View Abstract - PubMed 10942360]

  67. Zohn IE, Klinger M, Karp X, Kirk H, Symons M, Chrzanowska-Wodnicka M, Der CJ, Kay RJ. G2A is an oncogenic G protein-coupled receptor. Oncogene 19(34):3866-77. (2000).
     [View Abstract - PubMed 10951580]

    68. 1999

  68. Ailles LE, Gerhard B, Kawagoe H & Hogge DE. Growth characteristics of acute myelogenous leukemia progenitors that initiate malignant hematopoiesis in nonobese diabetic/severe combined immunodeficient mice. Blood 94: 1761-1772. (1999).

  69. Ailles LE, Humphries RK, Thomas TE & Hogge DE. Retroviral marking of acute myelogenous leukemia progenitors that initiate long-term culture and growth in immunodeficient mice. Exp Hematol 27: 1609-1620. (1999).

  70. Cashman JD & Eaves CJ. Human growth factor-enhanced regeneration of transplantable human hematopoietic stem cells in nonobese diabetic/severe combined immunodeficient mice. Blood 93: 481-487. (1999).

  71. Cashman JD, Clark-Lewis I, Eaves AC & Eaves CJ. Differentiation stage-specific regulation of primitive human hematopoietic progenitor cycling by exogenous and endogenous inhibitors in an in vivo model. Blood 94: 3722-3729. (1999).

  72. Doheny JG, Jervis EJ, Guarna MM, Humphries RK, Warren J & Kilburn DG. Cellulose as an inert matrix for presenting cytokines to target cells: production and properties of a stem cell factor-cellulose-binding domain fusion protein. Biochem J 339: 429-434. (1999).

  73. Glaven JA, Whitehead I, Bagrodia S, Kay R & Cerione RA. The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells. J Biol Chem 274: 2279-2285. (1999).
     [View Abstract - PubMed 9890991]

  74. Glimm H & Eaves CJ. Direct evidence for multiple self-renewal divisions of human in vivo repopulating hematopoietic cells in short-term culture. Blood 94: 2161-2168. (1999).

  75. Hande MP, Samper E, Lansdorp P & Blasco MA. Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice. J Cell Biol 144: 589-601. (1999).

  76. Hande P, Slijepcevic P, Silver A, Bouffler S, van Buul P, Bryant P & Lansdorp P. Elongated telomeres in scid mice. Genomics 56: 221-223. (1999).

  77. Hennemann B, Conneally E, Pawliuk R, LeBoulch P, Rose-John S, Reid D, Chuo JY, Humphries RK & Eaves CJ. Optimization of retroviral-mediated gene transfer to human NOD/SCID mouse repopulating cord blood cells through a systematic analysis of protocol variables. Exp Hematol 27: 817-825. (1999).

  78. Holyoake T, Jiang X, Eaves C & Eaves A. Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia. Blood 94: 2056-2064. (1999).

  79. Holyoake TL, Nicolini FE & Eaves CJ. Functional differences between transplantable human hematopoietic stem cells from fetal liver, cord blood, and adult marrow. Exp Hematol 27: 1418-1427. (1999).

  80. Jiang X, Lopez A, Holyoake T, Eaves A & Eaves C. Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia. Proc Natl Acad Sci USA 96: 12804-12809. (1999).

  81. Katz SG, Schneider SS, Bartuski A, Trask BJ, Massa H, Overhauser J, Lalande M, Lansdorp PM & Silverman GA. An 18q- syndrome breakpoint resides between the duplicated serpins SCCA1 and SCCA2 and arises via a cryptic rearrangment with satellite III DNA. Hum Mol Genet 8: 87-92. (1999).

  82. Kawagoe H, Humphries RK, Blair A, Sutherland HJ & Hogge DE. Expression of Hox genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells. Leukemia 13: 687-698. (1999).

  83. Kim CH, Hangoc G, Cooper S, Helgason CD, Yew S, Humphries RK, Krystal G & Broxmeyer HE. Altered responsiveness to chemokines due to targeted disruption of SHIP. J Clin Invest 104: 1751-1759. (1999).

  84. Kipling D, Wynford-Thomas D, Jones CJ, Akbar A, Aspinall R, Bacchetti S, Blasoc MA, Broccoli D, DePinho RA, Edwards DR, Effros RB, Harley CB, Lansdorp PM, Linskens MHK, Prowse KR, Newbold RF, Olovnikov AM, Parkinson EK, Pawelec G, Ponten J, Shall S, Zijlmans M & Faragher RGA. Telomere-dependent senescence (Letter). Nat Biotechnol 17: 313. (1999).

  85. Kowalski PE, Freeman JD & Mager DL. Intergenic splicing between a HERV-H endogenous retrovirus and two adjacent human genes. Genomics 57: 371-379. (1999).

  86. Kubota A, Kubota S, Farrell HE, Davis-Poynter N & Takei F. Inhibition of NK cells by murine CMV-encoded class I MHC homologue m144. Cell Immunol 191: 145-151. (1999).

  87. Kubota A, Kubota S, Lohwasser S, Mager DL & Takei F. Diversity of NK cell receptor repertoire in adult and neonatal mice. J Immunol 163: 212-216. (1999).

  88. Kubota A, Lian RH, Lohwasser S, Salcedo M & Takei F. IFN-g production and cytoxocity of IL-2-activated murine NK cells are differentially regulated by MHC class I molecules. J Immunol 163: 6488-6493. (1999).

  89. Lian RH, Kotwal GJ, Hunt LA, Wilson MA & Justus DE. Dextran sulfate inhibits IFN-g-induced Jak-Stat pathway in human vascular endothelial cells. Cell Immunol 192: 140-148. (1999).

  90. Lian RH, Li Y, Kubota S, Mager DL & Takei F. Recognition of class I MHC by NK receptor Ly-49C: Identification of critical residues. J Immunol 162: 7271-7276. (1999).

  91. Lindeskog M, Mager DL & Blomberg J. Isolation of a human endogenous retroviral HERV-H element with an open env reading frame. Virology 258: 441-450. (1999).

  92. Lohwasser S, Hande P, Mager DL & Takei F. Cloning of murine NKG2A, B and C: second family of C-type lectin receptors on murine NK cells. Eur J Immunol 29: 755-761. (1999).

  93. Mager DL, Hunter DG, Schertzer M & Freeman JD. Endogenous retroviruses provide the primary polyadenylation signal for two new human genes (HHLA2 and HHLA3). Genomics 59: 255-263. (1999).

  94. McQueen KL, Lohwasser S, Takei F & Mager DL. Expression analysis of new Ly49 genes: most transcripts of Ly49j lack the transmembrane domain. Immunogenetics 49: 685-691. (1999).

  95. Metzler M, Chen N, Helgason CD, Graham RK, Nichol K, McCutcheon K, Nasir J, Humphries RK, Raymond LA & Hayden MR. Life without huntingtin: normal differentiation into functional neurons. J Neurochem 72: 1009-1018. (1999).

  96. Nicolini FE, Holyoake TL, Cashman JD, Chu PPY, Lambie K & Eaves CJ. Unique differentiation programs of human fetal liver stem cells revealed both in vitro and in vivo in NOD/SCID mice. Blood 94: 2686-2695. (1999).

  97. Oostendorp RAJ, Audet J, Miller C & Eaves CJ. Cell division tracking and expansion of hematopoietic long-term repopulating cells. Leukemia 13: 499-501. (1999).

  98. Poon SSS, Martens UM, Ward RK & Lansdorp PM. Telomere length measurements using digital fluorescence microscopy. Cytometry 36: 267-278. (1999).

  99. Rabkin SW, Huber M & Krystal G. Modulation of palmitate-induced cardiomyocyte cell death by interventions that alter intracellular calcium. Prostaglandins Leukot Essent Fatty Acids 61: 195-201. (1999).

  100. Reece DE, Nevill TJ, Sayegh A, Spinelli JJ, Brockington DA, Barnett MJ, Klingemann H-G, Connors JM, Nantel SH, Shepherd JD, Sutherland HJ, Voss NJS, Fairey RN, O'Reilly SE & Phillips GL. Regimen-related toxicity and non-relapse mortality with high-dose cyclophosphamide, carmustine (BCNU) and etoposide (VP16-213) (CBV) and CBV plus cisplatin (CBVP) followed by autologous stem cell transplantation in patients with Hodgkin's disease. Bone Marrow Transplant 23: 1131-1138. (1999).

  101. Rey-Ladino JA, Huber M, Liu L, Damen JE, Krystal G & Takei F. The SH2-containing inositol-5'-phosphatase, SHIP, enhances LFA-1-mediated cell adhesion and defines two signaling pathways for LFA-1 activation. J Immunol 162: 5792-5799. (1999).

  102. Rufer N, Brummendorf TH, Kolvraa S, Bischoff C, Christensen K, Wadsworth L, Schultzer M & Lansdorp PM. Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. J Exp Med 190: 157-167. (1999).

  103. Sprung CN, Afshar G, Chavez EA, Lansdorp P, Sabatier L & Murnane JP. Telomere instability in a human cancer cell line. Mutat Res 429 (Suppl 2): 209-223. (1999).

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     [View Abstract - PubMed 11012149]

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  225. Korbelik M, Krosl G, Krosl J & Dougherty GJ. Modulation of tumor response to photodynamic therapy in severe combined immunodeficient (SCID) mice by adoptively transferred lymphoid cells. SPIE 2675: 156-162. (1996).

  226. Korbelik M, Krosl G, Krosl J & Dougherty GJ. The role of host lymphoid populations in the response of mouse EMT6 tumor to photodynamic therapy. Cancer Res 56: 5647-5652. (1996).

  227. Krosl G, Korbelik M, Krosl J & Dougherty GJ. Potentiation of photodynamic therapy-elicited antitumor response by localized treatment with granulocyte-macrophage colony-stimulating factor. Cancer Res 56: 3281-3286. (1996).

  228. Krosl J, Damen JE, Krystal G & Humphries RK. Interleukin-3 (IL-3) inhibits erythropoietin-induced differentiation in Ba/F3 cells via the IL-3 receptor a subunit. J Biol Chem 271: 27432-27437. (1996).

  229. Kumasaka T, Quinlan WM, Doyle NA, Condon TP, Sligh J, Takei F, Beaudet AL, Bennett CF & Doerschuk CM. Role of the intercellular adhesion molecule-1 (ICAM-1) in endotoxin-induced pneumonia evaluated using ICAM-1 antisense oligonucleotides, anti-ICAM-1 monoclonal antibodies, and ICAM-1 mutant mice. J Clin Invest 97: 2362-2369. (1996).

  230. Lansdorp P. Les cellules souches hematopoietiques s'autorenouvellent-elles? Hematologie 2: 217-223. (1996).

  231. Lansdorp PM. Close encounters of the PNA kind. Nat Biotechnol 14: 1653-1653. (1996).

  232. Lansdorp PM, Verwoerd NP, van de Rijke FM, Dragowska V, Little M-T, Dirks RW, Raap AK & Tanke HJ. Heterogeneity in telomere length of human chromosomes. Hum Mol Genet 5: 685-691. (1996).

  233. Lawrence HJ, Sauvageau G, Humphries RK & Largman C. The role of HOX homeobox genes in normal and leukemic hematopoiesis. Stem Cells 14: 281-291. (1996).

  234. Lemieux ME & Eaves CJ. Identification of properties that can distinguish primitive populations of stromal cell-responsive lympho-myeloid cells from cells that are stromal cell-responsive but lymphoid-restricted and cells that have lympho-myeloid potential but are also capable of competitively repopulating myeloablated recipients. Blood 88: 1639-1648. (1996).

  235. Liu L, Jefferson AB, Zhang X, Norris FA, Majerus PW & Krystal G. A novel phosphatidylinositol 3,4,5 trisphosphate 5-phosphatase associates with the interleukin-3 receptor. J Biol Chem 271: 29729-29733. (1996).

  236. Maguer-Satta V, Petzer AL, Eaves AC & Eaves CJ. BCR-ABL expression in different subpopulations of functionally characterized Ph+ CD34+ cells from patients with chronic myeloid leukemia. Blood 88: 1796-1804. (1996).

  237. McBride WH, Economou JS, Syljausen R, Parrish C, Hackman D, Latham V, Chiang CS & Dougherty GJ. The effects of cytokine gene transfer into tumors on host cell infiltration and regression. Anticancer Res 16: 1139-1144. (1996).

  238. Medin JA, Migita M, Pawliuk R, Jacobson S, Amiri M, Kluepfel-Stahl S, Brady RO, Humphries RK & Karlsson S. A bicistronic therapeutic retroviral vector enables sorting of transduced CD34+ cells and corrects the enzyme deficiency in cells from Gaucher patients. Blood 87: 1754-1762. (1996).

  239. Miller CL, Rebel VI, Lemieux ME, Helgason CD, Lansdorp PM & Eaves CJ. Studies of W mutant mice provide evidence for alternate mechanisms capable of activating hematopoietic stem cells. Exp Hematol 24: 185-194. (1996).

  240. Nelson DT, Goodchild NL & Mager DL. Gain of Sp1 sites and loss of repressor sequences associated with a young, transcriptionally active subset of HERV-H endogenous long terminal repeats. Virology 220: 213-218. (1996).

  241. Pawliuk R, Eaves C & Humphries RK. Evidence of both ontogeny and transplant dose-regulated expansion of hematopoietic stem cells in vivo. Blood 88: 2852-2858. (1996).

  242. Petzer AL, Eaves CJ, Lansdorp PM, Ponchio L, Barnett MJ & Eaves AC. Characterization of primitive subpopulations of normal and leukemic cells present in the blood of patients with newly diagnosed as well as established chronic myeloid leukemia. Blood 88: 2162-2171. (1996).

  243. Petzer AL, Hogge DE, Lansdorp PM, Reid DS & Eaves CJ. Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium. Proc Natl Acad Sci USA 93: 1470-1474. (1996).

  244. Petzer AL, Zandstra PW, Piret JM & Eaves CJ. Differential cytokine effects on primitive (CD34+CD38-) human hematopoietic cells: novel responses to flt3-ligand and thrombopoietin. J Exp Med 183: 2551-2558. (1996).

  245. Qin L, Quinlan WM, Doyle NA, Graham L, Sligh JE, Takei F, Beaudet AL & Doerschuk CM. The roles of CD11/CD18 and ICAM-1 in acute Pseudomonas aeruginosa-induced pneumonia in mice. J Immunol 157: 5016-5021. (1996).

  246. Rabkin SW, Damen JE, Goutsouliak V & Krystal G. Cardiac hypertrophy is associated with increased tyrosine phosphorylation of a 120 kDa cytosolic protein. Am J Hypertens 9: 230-236. (1996).

  247. Rajotte D, Sadowski HB, Haman A, Gopalbhai K, Meloche S, Liu L, Krystal G & Hoang T. Contribution of both STAT and SRF/TCF to c-fos promoter activation by GM-CSF. Blood 88: 2906-2916. (1996).

  248. Rebel VI & Lansdorp PM. Culture of purified stem cells from fetal liver results in loss of in vivo repopulating potential. J Hematother 5: 25-37. (1996).

  249. Rebel VI, Miller CL, Eaves CJ & Lansdorp PM. The repopulation potential of fetal liver hematopoietic stem cells in mice exceeds that of their adult bone marrow counterparts. Blood 87: 3500-3507. (1996).

  250. Rebel VI, Miller CL, Thornbury GR, Dragowska WH, Eaves CJ & Lansdorp PM. A comparison of long-term repopulating hematopoietic stem cells in fetal liver and adult bone marrow from the mouse. Exp Hematol 24: 638-648. (1996).

  251. Shen W-F, Chang C-P, Rozenfeld S, Sauvageau G, Humphries RK, Lu M, Lawrence HJ, Cleary ML & Largman C. HOX homeodomain proteins exhibit selective complex stabilities with Pbx and DNA. Nucleic Acids Res 24: 898-906. (1996).

  252. Sirard C, Lapidot T, Vormoor J, Cashman JD, Doedens M, Murdoch B, Jamal N, Messner H, Addey L, Minden M, Laraya P, Keating A, Eaves A, Lansdorp PM, Eaves CJ & Dick JE. Normal and leukemic SCID-repopulating cells (SRC) co-exist in the bone marrow and peripheral blood from CML patients in chronic phase while leukemic SRC are detected in blast crisis. Blood 87: 1539-1548. (1996).

  253. Sutherland HJ, Blair A & Zapf RW. Characterization of a hierarchy in human acute myeloid leukemia progenitor cells. Blood 87: 4754-4761. (1996).

  254. Tauchi T, Damen JE, Toyama K, Feng G-S, Broxmeyer HE & Krystal G. Tyrosine 425 within the activated erythropoietin receptor binds Syp, reduces the erythropoietin required for Syp tyrosine phosphorylation and promotes mitogenesis. Blood 87: 4495-4501. (1996).

  255. Ware MD, Rosten P, Damen JE, Liu L, Humphries RK & Krystal G. Cloning and characterization of the human 145 kDa SHC-associated inositol 5-phosphatase, SHIP. Blood 88: 2833-2840. (1996).

  256. Watari K, Mayani H, Lee F, Dragowska W, Lansdorp PM & Schrader JW. Production of interleukin 1b by human hematopoietic progenitor cells. J Clin Invest 97: 1666-1674. (1996).

  257. Whitehead IP, Khosravi-Far R, Kirk H, Trigo-Gonzalez G, Der CJ & Kay R. Expression cloning of Lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors. J Biol Chem 271: 18643-18650. (1996).

  258. Wong EK, Eaves C & Klingemann H-G. Comparison of natural killer activity of human bone marrow and blood cells in cultures containing IL-2, IL-7 and IL-12. Bone Marrow Transplant 18: 63-71. (1996).

  259. Xu H, Bickford JK, Luther E, Carpenito C, Takei F & Springer TA. Characterization of murine intercellular adhesion molecule-2. J Immunol 156: 4909-4914. (1996).

    260. 1995

  260. Asman DC, Dirks JF, Lisheng G, Resnick NM, Salvucci LA, Gau J-T, Becich MJ, Dougherty GJ & Cooper DL. Gene therapeutic approach to primary and metastatic brain tumors. I. CD44 variant pre-mRNA alternative splicing as a VDEPT control element. J Neurooncol 26: 243-250. (1995).

  261. Brennan J, Takei F, Wong S & Mager DL. Carbohydrate recognition by a natural killer cell receptor, Ly- 49C. J Biol Chem 270: 9691-9694. (1995).

  262. Carpenito C, Ohh M & Takei F. Cloning and characterization of murine intercellular adhesion molecule-2 (ICAM-2): A functional and molecular analysis. Allergy Immunol (Life Sci Adv ) 14: 43-51. (1995).

  263. Chiu RK, Droll A, Cooper DL, Dougherty ST, Dirks JF & Dougherty GJ. Molecular mechanism regulating the hyaluronan binding activity of the adhesion protein CD44. J Neurooncol 26: 231-239. (1995).

  264. Clarke MR, Landreneau RJ, Resnick NM, Crowley R, Dougherty GJ, Cooper DL & Yousem SA. Prognostic significance of CD44 expression in adenocarcinoma of the lung. J Clin Pathol 48: M200-M204. (1995).

  265. Cooper DL & Dougherty GJ. To metastasize or not? Selection of CD44 splice sites. Nat Med 1: 635-637. (1995).

  266. Cornell RB, Kalmar GB, Kay RJ, Johnson MA, Sanghera JS & Pelech SL. Functions of the C-terminal domain of CTP: phosphocholine cytidylyltransferase: Effects of C-terminal deletions on enzyme activity, intracellular localization, and phosphorylation potential. Biochem J 310: 699-708. (1995).

  267. Damen JE, Cutler RL, Jiao H, Yi T & Krystal G. Phosphorylation of Y503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR associated PI 3-kinase activity. J Biol Chem 270: 23402-23408. (1995).

  268. Damen JE, Wakao H, Miyajima A, Krosl J, Humphries RK, Cutler RL & Krystal G. Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and STAT5 activation. EMBO J 14: 5557-5568. (1995).

  269. Dougherty GJ, Dougherty ST, Dirks JF, Chui RK, Peters CE & Droll A. Regulation of the functional activity and ligand binding specificity of the adhesion protein CD44. Trends Glycosci Glycotechnol 7: 45-56. (1995).

  270. Droll A, Dougherty ST, Chiu RK, Dirks JF, McBride WH, Cooper DL & Dougherty GJ. Adhesive interactions between alternatively spliced CD44 isoforms. J Biol Chem 270: 11567-11573. (1995).

  271. Dubinett SM, Huang M, Dhanani S, Dougherty GJ, Wang J & McBride WH. Downregulation of murine fibrosarcoma transforming growth factor-b1 expression by IL-7. J Natl Cancer Inst 87: 593-597. (1995).

  272. Fung H, Shepherd JD, Naiman SC, Barnett MJ, Reece DE, Horsman DE, Nantel SH, Sutherland HJ, Spinelli JJ, Klingemann H-G & Phillips GL. Acute monocytic leukemia: a single institution experience. Leuk Lymphoma 19: 259-265. (1995).

  273. Ghaffari S, Dougherty GJ, Lansdorp PM, Eaves AC & Eaves CJ. Differentiation - associated changes in CD44 isoform expression during normal hematopoiesis and their alteration in chronic myeloid leukemia. Blood 86: 2976-2985. (1995).

  274. Goodchild NL, Freeman JD & Mager DL. Spliced HERV-H endogenous retroviral sequences in human genomic DNA:evidence for amplification via retrotransposition. Virology 206: 164-173. (1995).

  275. Hogge DE, McConnell M, Jacobson C, Sutherland HJ, Benny WB & Massing BG. Platelet refractoriness and allosensitization in pediatric oncology and bone marrow transplant patients. Transfusion 35: 645-652. (1995).

  276. Klingemann H-G. Introducing graft-versus-leukemia into autologous stem cell transplantation. J Hematother 4: 261-267. (1995).

  277. Klingemann H-G & Phillips GL. Is there a place for immunotherapy with interleukin-2 to prevent relapse after autologous stem cell transplantation for acute leukemia? Leuk Lymphoma 16: 397-405. (1995).

  278. Krosl G, Korbelik M & Dougherty GJ. Induction of immune cell infiltration into murine SCCVII tumor by photodynamic therapy. Br J Cancer 71: 549-555. (1995).

  279. Krosl J, Damen JE, Krystal G & Humphries RK. Erythropoietin and interleukin-3 induce distinct events in erythropoietin receptor-expressing BA/F3 cells. Blood 85: 50-56. (1995).

  280. Krystal G, Humphries K & Damen J. A second erythropoietin receptor subunit (letter). Blood 85: 2641. (1995).

  281. Lansdorp PM. Telomere length and proliferation potential of hematopoietic stem cells. J Cell Sci 108: 1-6. (1995).

  282. Lansdorp PM. Developmental changes in the function of hematopoietic stem cells. Exp Hematol 23: 187-191. (1995).

  283. Lawrence HJ, Sauvageau G, Ahmadi N, Lopez AR, Lebeau MM, Link M, Humphries K & Largman C. Stage- and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells. Exp Hematol 23: 1160-1166. (1995).

  284. Lemieux ME, Rebel VI, Lansdorp PM & Eaves CJ. Characterization and purification of a primitive hematopoietic cell type in adult mouse marrow capable of lympho-myeloid differentiation in long-term marrow "switch" cultures. Blood 86: 1339-1347. (1995).

  285. Lewis MES, Forsythe IJ, Marth JD, Brunzell JD, Hayden MR & Humphries RK. Retroviral-mediated gene transfer and expression of human lipoprotein lipase in somatic cells. Hum Gene Ther 6: 853-863. (1995).

  286. Liu L, Cutler RL & Krystal G. Identification and characterization of an interleukin-3 receptor associated 110 kDa serine/threonine kinase. J Biol Chem 270: 22422-22427. (1995).

  287. Mager DL & Freeman JD. HERV-H endogenous retroviruses: presence in the New World branch but amplification in the Old World primate lineage. Virology 213: 395-404. (1995).

  288. Mayani H & Lansdorp PM. Proliferation of individual hematopoietic progenitors purified from umblical cord blood. Exp Hematol 23: 1453-1462. (1995).

  289. Mayani H, Little MT, Dragowska W, Thornbury G & Lansdorp PM. Differential effects of the hematopoietic inhibitors MIP-1a, TGF-b, and TNF-a on cytokine-induced proliferation of subpopulations of CD34+ cells purified from cord blood and fetal liver. Exp Hematol 23: 422-427. (1995).

  290. McBride WH & Dougherty GJ. Radiotherapy for genes that cause cancer. Nat Med 1: 1215-1217. (1995).

  291. McBride WH, Economou JS, Kuber N, Ji-Hong H, Chiang C-S, Syljuasen R, Dougherty ST & Dougherty GJ. Modification of the tumor micro-environment by cytokine gene transfer. Acta Oncol 34: 447-451. (1995).

  292. Migita M, Medin JA, Pawliuk R, Jacobson S, Nagle JW, Anderson S, Amiri M, Humphries RK & Karlsson S. Selection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectors. Proc Natl Acad Sci USA 92: 12075-12079. (1995).

  293. Nordlund JJ, Csato M, Babcock G & Takei F. Low ICAM-1 expression in the epidermis of depigmenting C57BL/6J-mivit/mivit mice: a possible cause of muted contact sensitization. Exp Dermatol 4: 20-29. (1995).

  294. Ohh M & Takei F. Regulation of ICAM-1 mRNA stability by cycloheximide: Role of serine/threonine phosphorylation and protein synthesis. J Cell Biochem 59: 202-213. (1995).

  295. Phillips GL, Nevill TJ, Spinelli JJ, Nantel SH, Klingemann H-G, Barnett MJ, Shepherd JD, Chan K, Meharchand JM, Sutherland HJ, Reece DE & Messner HA. Prophylaxis for acute graft-versus-host disease following unrelated-donor bone marrow transplantation. Bone Marrow Transplant 15: 213-219. (1995).

  296. Ponchio L, Conneally E & Eaves C. Quantitation of the quiescent fraction of longterm culture-initiating cells (LTC-IC) in normal human blood and marrow and the kinetics of their growth factor-stimulated entry into S-phase in vitro. Blood 86: 3314-3321. (1995).

  297. Przepiorka D, Weisdorf D, Martin P, Klingemann H-G, Beatty P, Hows J & Thomas ED. Consensus conference on acute GVHD grading. Bone Marrow Transplant 15: 825-828. (1995).

  298. Rebel VI, Miller CL, Spinelli JJ, Thomas TE, Eaves CJ & Lansdorp PM. Nonlinear effects of radiation dose on donor-cell reconstitution by limited numbers of purified stem cells. Biol Blood Marrow Transplant 1: 32-39. (1995).

  299. Reece DE, Barnett MJ, Shepherd JD, Hogge DE, Klasa RJ, Nantel SH, Sutherland HJ, Klingemann H-G, Fairey RN, Voss NJ, Connors JM, O'Reilly SE & Phillips GL. High-dose cyclophosphamide, BCNU, and VP16-213 with or without cisplatin (CBV±P) and autologous transplantation for patients with Hodgkin's disease who fail to enter a complete remission after combination chemotherapy. Blood 86: 451-456. (1995).

  300. Reece DE, Shepherd JD, Klingemann H-G, Sutherland HJ, Nantel SH, Barnett MJ, Spinelli JJ & Phillips GL. Treatment of myeloma using intensive therapy and allogeneic bone marrow transplantation. Bone Marrow Transplant 15: 117-123. (1995).

  301. Sauvageau G, Thorsteinsdottir U, Eaves CJ, Lawrence HJ, Largman C, Lansdorp PM & Humphries RK. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo . Genes Dev 9: 1753-1765. (1995).

  302. Tezcan H, Barnett MJ, Bredeson CN, Reece DE, Shepherd JD, Dalal BI, Horsman DE, Klingemann H-G, Nantel SH, Spinelli JJ, Sutherland HJ & Phillips GL. Treatment of acute promyelocytic leukemia in patients presenting at Vancouver General Hospital from 1983 to 1992. Leuk Lymphoma 16: 439-444. (1995).

  303. Whitehead I, Kirk H & Kay R. Retroviral transduction and oncogenic selection of a cDNA encoding Dbs, a homolog of the Dbl guanine nucleotide exchange factor. Oncogene 10: 713-721. (1995).

  304. Whitehead I, Kirk H & Kay R. Expression cloning of oncogenes by retroviral transfer of cDNA libraries. Mol Cell Biol 15: 704-710. (1995).

  305. Whitehead I, Kirk H, Tognon C, Trigo-Gonzalez G & Kay R. Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C. J Biol Chem 270: 18388-18395. (1995).
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