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2009

1. Evdokimova V, Tognon C, Ng T, Ruzanov P, Melnyk N, Fink D, Sorokin A, Ovchinnikov LP, Davicioni E, Triche TJ, Sorensen PH. Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transition. Cancer Cell. 15(5):402-15. (2009).
    [View Abstract - PubMed 19411069]  Request Paper

2007

2. Zhe L, Tognon C, Godinho F, Yasaitis L, Hock H, Herschkowitz JI, Lannon C, Che E, Kim S-J, Bronson RT, Perou, CM, Sorensen PHB, and Orkin SH. ETV6-NTRK3 fusion oncogene initiates breast cancer from bipotent alveolar progenitors via activation of AP1 complex Cancer Cell 12: 542-558 (2007).
    [View Abstract - PubMed 18068631]  Request Paper

2005

3. Jin W, Kim B-C, Tognon C, Lee H-J, Patel S, Triche TJ, Sorensen PHB, and Kim S-J. The ETV6-NTRK3 gene fusion product suppresses TGF-beta signaling by binding to TGF-beta type II receptor PNAS 102 : 16239-16244 (2005).
    [View Abstract - PubMed 16258068]  Request Paper

2004

4. Tognon C, Mackereth CD, Somasiri AM, McIntosh LP, and Sorensen PHB. Mutations in the SAM domain of the ETV6-NTRK3 chimeric tyrosine kinase block polymerization and transformation activity Mol Cell Biol 24: 4636-4650 (2004).
    [View Abstract - PubMed 15143160]  Request Paper

2003

5. Daillo R, Tognon C, Knezevich SR, Sorensen P, and Poremba C. Secretory carcinoma of the breast: a genetically defined carcinoma entity Verh Dtsch Ges Pathol 87: 193-203 (2003).
    [View Abstract - PubMed 16888913]  Request Paper

6. Lannon CL, Martin MJ, Tognon C, Jin W, Kim S-J, and Sorensen PHB. A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the PTB domain of IRS-1: an essential interaction for transformation J Biol Chem 279: 6225-6234 (2003).
    [View Abstract - PubMed 14668342]  Request Paper

2002

7. Morrison KB, Tognon C, Garnett MJ, and Sorensen PHB. ETV6-NTRK3 associates with insulin receptor substrate-1 (IRS-1) and requires the insulin-like growth factor receptor (IGF-IR) for transformation of murine fibroblasts Oncogene 37: 5684-5695 (2002).
    [View Abstract - PubMed 12173038]  Request Paper

8. Tognon C, Knezevich SR, Huntsman D, Roskelley CD, Melnyk N, Mathers JA, Becker L, Carneiro R, MacPherson N, Horsman D, Poremba C, and Sorensen PHB. Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma Cancer Cell 2: 367-376 (2002).
    [View Abstract - PubMed 12450792]  Request Paper

2001

9. Tognon C, Garnett M, Kenward E, Kay R, Morrison K, and Sorensen PHB. The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-Kinase-Akt signaling for fibroblast transformation Cancer Research 61: 8909-8916 (2001).
    [View Abstract - PubMed 11751416]  Request Paper

1998

10. Tognon C, Kirk HE, Passmore LA, Whitehead IP, Der CJ, and Kay RJ. Expression cloning of RasGRP: A homologue of the Sos family of guanine nucleotide exchange factors, which is regulated via a phorbol ester-responsive C1 domain Mol Cell Biol 18: 6995-7008 (1998).
     [View Abstract - PubMed 9819387]  Request Paper

1997

11. Hota-Mitchell S, Siddiqui AA, Smith J, Dekeban GA, Tognon C, and Podesta RB. Protection against Schistosoma mansoni infection with a recombinant baculovirus-expressed subunit of calpain Vaccine 15: 1631-1640 (1997).
     [View Abstract - PubMed 9364694]  Request Paper

1995

12. Whitehead I, Kirk H, Tognon C, Trigo-Gonzalez G, and Kay R. Retroviral-mediated expression cloning of lfc, a novel oncogene with structural similarities to the CDC24 family of guanine nucleotide exchange factors and to the regulatory region of protein kinase C J Biol Chem 270: 183888-18395 (1995).
     [View Abstract - PubMed 7629163]  Request Paper

1993

13. Siddiqui AA, Zhou Y, Podesta RB, Karcz SR, Tognon C, Clarke MW, Strejan GH, and Dekaban GA. Characterization of Ca (2+)-dependent neutral protease (calpain) from human blood flukes, Schistosoma mansoni Biochimica et Biophysica Acta 1181: 37- 44 (1993).
     [View Abstract - PubMed 8457603]  Request Paper

2003

1. Tognon C, Huntsman D, and Sorensen PHB. Expression of the ETV6-NTRK3 gene fusion in human secretory breast carcinoma Handbooks: Immunohistochemistry and In situ hybridization of human carcinomas. Elsevier Science/Academic Press, Volume II (2003).
    Request Paper