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2006

1. Jankovic B, Aquino-Parsons C, Raleigh JA, Stanbridge EJ, Durand RE, Banath JP, Macphail SH, Olive PL. Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix. Cytometry B Clin Cytom. . (2006).
    [View Abstract - PubMed 16456867]  Request Paper

2. Klokov D, MacPhail SM, Banath JP, Byrne JP, Olive PL. Phosphorylated histone H2AX in relation to cell survival in tumor cells and xenografts exposed to single and fractionated doses of X-rays. Radiother Oncol. 80(2):223-9, 2006. (2006).
    [View Abstract - PubMed 16905207]  Request Paper

3. Olive PL. In regard to Mahrhofer et al.: Radiation induced DNA damage and damage repair in human tumor and fibroblast cell lines assessed by histone H2AX phosphorylation (Int J Radiat Oncol Biol Phys 2006;64:573-580). Int J Radiat Oncol Biol Phys. 65(3):956; author reply 956-7. (2006).
    [View Abstract - PubMed 16751080]  Request Paper

4. Olive PL, Banath JP. The comet assay: a method to measure DNA damage in individual cells. Nat Protoc. 1(1):23-9. (2006).
    [View Abstract - PubMed 17406208]  Request Paper

5. Yu T, MacPhail SH, Banath JP, Klokov D, Olive PL. Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability. DNA Repair (Amst). 5:935-46, 2006. (2006).
    [View Abstract - PubMed 16814620]  Request Paper

2005

6. Banath JP, Sinnott L, Larrivee B, MacPhail SH, Olive PL. Growth of V79 cells as xenograft tumors promotes multicellular resistance but does not increase spontaneous or radiation-induced mutant frequency. Radiat Res. 164(6):733-44. (2005).
    [View Abstract - PubMed 16296879]  Request Paper

7. Olive PL, Durand RE. Heterogeneity in DNA damage using the comet assay. Cytometry A. 66(1):1-8. (2005).
    [View Abstract - PubMed 15924303]  Request Paper

8. Reitsema T, Klokov D, Banath JP, Olive PL. DNA-PK is responsible for enhanced phosphorylation of histone H2AX under hypertonic conditions. DNA Repair (Amst). 4(10):1172-81. (2005).
    [View Abstract - PubMed 16046194]  Request Paper

9. Sobhanifar S, Aquino-Parsons C, Stanbridge EJ, Olive PL. Reduced expression of HIF-1α in perinecrotic regions of solid tumors Cancer Res 65(16):7259-66 (2005).
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2004

10. Banath JP, Macphail SH, Olive PL. Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines. Cancer Res 64(19):7144-9. (2004).
     [View Abstract - PubMed 15466212]  Request Paper

11. Olive PL. Detection of DNA damage in individual cells by analysis of histone H2AX phosphorylation. Methods Cell Biol 75:355-73. (2004).
     [View Abstract - PubMed 15603433]  Request Paper

12. Olive PL, Aquino-Parsons C. Measurement of tumor hypoxia using single-cell methods. Semin Radiat Oncol 14(3):241-8. (2004).
     [View Abstract - PubMed 15254867]  Request Paper

13. Olive PL, Banath JP. Phosphorylation of histone H2AX as a measure of radiosensitivity. Int J Radiat Oncol Biol Phys 58(2):331-5. (2004).
     [View Abstract - PubMed 14751500]  Request Paper

14. Olive PL, Banath JP, Sinnott LT. Phosphorylated histone H2AX in spheroids, tumors, and tissues of mice exposed to etoposide and 3-amino-1,2,4-benzotriazine-1,3-dioxide. Cancer Res 64(15):5363-9. (2004).
     [View Abstract - PubMed 15289343]  Request Paper

15. Reitsema TJ, Banath JP, MacPhail SH, Olive PL. Hypertonic saline enhances expression of phosphorylated histone H2AX after irradiation. Radiat Res 161(4):402-8. (2004).
     [View Abstract - PubMed 15038772]  Request Paper

2003

16. Banath JP, Olive PL. Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks. Cancer Res 63(15):4347-50. (2003).
     [View Abstract - PubMed 12907603]  Request Paper

17. MacPhail SH, Banath JP, Yu TY, Chu EH, Lambur H, Olive PL. Expression of phosphorylated histone H2AX in cultured cell lines following exposure to X-rays. Int J Radiat Biol 79(5):351-8. (2003).
     [View Abstract - PubMed 12943243]  Request Paper

18. MacPhail SH, Banath JP, Yu Y, Chu E, Olive PL. Cell cycle-dependent expression of phosphorylated histone H2AX: reduced expression in unirradiated but not X-irradiated G1-phase cells. Radiat Res 159(6):759-67. (2003).
     [View Abstract - PubMed 12751958]  Request Paper

2002

19. Olive PL, Banath JP, Durand RE. The Range of Oxygenation in SiHa Tumor Xenografts. Radiat Res 158(2):159-66. (2002).
     [View Abstract - PubMed 12105985]  Request Paper

20. Olive PL, Luo C, Banáth JP. Local hypoxia is produced at sites of intratumor injection Br J Cancer 86:429-435 (2002).
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21. Oloumi A, Lam W, Banath JP, Olive PL. Identification of genes differentially expressed in V79 cells grown as multicell spheroids. Int J Radiat Biol 78(6):483-92. (2002).
     [View Abstract - PubMed 12065053]  Request Paper

2001

22. MacPhail SH, Olive PL. RPA foci are associated with cell death after irradiation. Radiat Res 55:672-679 (2001).
     [View Abstract - PubMed 11302763]  Request Paper

23. Olive PL, Aquino-Parsons C, MacPhail SH, Liao SY, Raleigh JA, Lerman MI, Stanbridge EJ. Carbonic anhydrase 9 as an endogenous marker for hypoxic cells in cervical cancer. Cancer Res 61(24):8924-9. (2001).
     [View Abstract - PubMed 11751418]  Request Paper

24. Olive PL, Banath JP, Aquino-Parsons C. Measuring hypoxia in solid tumours--is there a gold standard? Acta Oncol 40(8):917-23. (2001).
     [View Abstract - PubMed 11845955]  Request Paper

2000

25. Olive PL, Durand RE, Raleigh JA, Luo C, Aquino-Parsons C. Comparison between the comet assay and pimonidazole binding for measuring tumor hypoxia. Brit J Cancer 83:1525-1531 (2000).
     [View Abstract - PubMed 11076663]  Request Paper

26. Oloumi A, MacPhail SH, Johnston PJ, Banath JP, Olive PL. Changes in subcellular distribution of topoisomerase II α correlate with etoposide resistance in spheroids. Cancer Res 60:5747-5753 (2000).
     [View Abstract - PubMed 11059769]  Request Paper

1999

27. Aquino-Parsons C, Luo C, Vikse CM, Olive PL. Comparison between the comet assay and the oxygen microelectrode for measurement of tumour hypoxia. Radiother and Oncol 51:179-185 (1999).
     [View Abstract - PubMed 10435811]  Request Paper

28. Banath JP, Wallace SS, Thompson J, Olive PL. Radiation-induced DNA base damage detected in individual aerobic and hypoxic cells with endonuclease III and formamidopyrimidine-glycosylase. Radiat Res 151:550-558 (1999).
     [View Abstract - PubMed 10319728]  Request Paper

29. Olive PL. DNA damage and repair in individual cells: applications of the comet assay in radiobiology. Inter J Radiat Biol 75:395-405 (1999).
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30. Olive PL, Durand RE, Jackson SM, LeRiche JC, Luo C, Ma R, McLaren DB, Aquino-Parsons C, Thomson TA, Trotter T. The comet assay in clinical practice. Acta Oncologica 38:839-844 (1999).
     [View Abstract - PubMed 10606413]  Request Paper

2004

1. Olive, PL. Detection of DNA damage in individual cells by analysis of histone H2AX phosphorylation Methods in Cell Biol 75:355-373. (2004).
    Request Paper

2001

2. Olive PL, Durand RE, Banath JP, Johnston PJ. Analysis of DNA damage in individual cells. Methods Cell Biol 64:235-49. (2001).
    [View Abstract - PubMed 11070842]  Request Paper