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2009

1. Freeman JD, Warren RL, Webb JR, Nelson BH, Holt RA. Profiling the T-cell receptor beta-chain repertoire by massively parallel sequencing. Genome Res. 19(10):1817-24. Epub 2009 Jun 18. (2009).
    [View Abstract - PubMed 19541912]  Request Paper

2. Hahn S, Nesslinger NJ, Drapala RJ, Bowden M, Rennie PS, Pai HH, Ludgate C, Nelson BH. Castration induces autoantibody and T cell responses that correlate with inferior outcomes in an androgen-dependent murine tumor model. Int J Cancer. 125(12):2871-8. (2009).
    [View Abstract - PubMed 19554630]  Request Paper

3. Martin ML, Wall EM, Sandwith E, Girardin A, Milne K, Watson PH, Nelson BH. Density of tumour stroma is correlated to outcome after adoptive transfer of CD4(+) and CD8 (+) T cells in a murine mammary carcinoma model. Breast Cancer Res Treat. 2009 Sep 30. (2009).
    [View Abstract - PubMed 19789976]  Request Paper

4. Milne K, Kobel M, Kalloger SE, Barnes RO, Gao D, Gilks CB, Watson PH, Nelson BH. Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors. PLoS One. 2009 Jul 29;4(7):e6412. (2009).
    [View Abstract - PubMed 19641607]  Request Paper

5. Warren RL, Nelson BH, Holt RA. Profiling model T-cell metagenomes with short reads. Bioinformatics. 25(4):458-64. Epub 2009 Jan 9. (2009).
    [View Abstract - PubMed 19136549]  Request Paper

6. Yang T, Martin ML, Nielsen JS, Milne K, Wall EM, Lin W, Watson PH, Nelson BH. Mammary tumors with diverse immunological phenotypes show differing sensitivity to adoptively transferred CD8+ T cells lacking the Cbl-b gene. Cancer Immunol Immunother. 2009 Apr 7. (2009).
    [View Abstract - PubMed 19350239]  Request Paper

2008

7. Milne K, Barnes RO, Girardin A, Mawer MA, Nesslinger NJ, Ng A, Nielsen JS, Sahota R, Tran E, Webb JR, Wong MQ, Wick DA, Wray A, McMurtrie E, Kobel M, Kalloger SE, Gilks CB, Watson PH, Nelson BH. Tumor-infiltrating T cells correlate with NY-ESO-1-specific autoantibodies in ovarian cancer. PLoS ONE. 3(10):e3409. Epub 2008 Oct 15. (2008).
    [View Abstract - PubMed 18923710]  Request Paper

8. Nelson BH. The impact of T cell immunity on ovarian cancer outcomes. Immunological Reviews (2008).
    [View Abstract - PubMed 18363996]  Request Paper

9. Nesslinger, N.J., Pai, H.H., Ludgate, C.M., Nelson, B.H.. Exploring the effects of standard treatments on the immune response to prostate cancer Methods of cancer diagnosis, therapy, and prognosis. Springer, Vol. 2. (2008).
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10. Palmer C, Duan X, Hawley S, Scholler N, Thorpe JD, Sahota RA, Wong MQ, Wray A, Bergan LA, Drescher CW, McIntosh MW, Brown PO, Nelson BH, Urban N. Systematic evaluation of candidate blood markers for detecting ovarian cancer. PLoS ONE. 2008 Jul 9;3(7):e2633. (2008).
     [View Abstract - PubMed 18612378]  Request Paper

2007

11. Lockyer HM, Tran E, Nelson BH. STAT5 Is Essential for Akt/p70S6 Kinase Activity during IL-2-Induced Lymphocyte Proliferation. J Immunol. 179(8):5301-8. (2007).
     [View Abstract - PubMed 17911616]  Request Paper

12. Nesslinger NJ, Sahota RA, Stone B, Johnson K, Chima N, King C, Rasmussen D, Bishop D, Rennie PS, Gleave M, Blood P, Pai H, Ludgate C, Nelson BH. Standard treatments induce antigen-specific immune responses in prostate cancer. Clin Cancer Res. 13(5):1493-502. (2007).
     [View Abstract - PubMed 17332294]  Request Paper

13. Thorpe JD, Duan X, Forrest R, Lowe K, Brown L, Segal E, Nelson B, Anderson GL, McIntosh M, Urban N. Effects of blood collection conditions on ovarian cancer serum markers. PLoS ONE. 2007 Dec 5;2(12):e1281. (2007).
     [View Abstract - PubMed 18060075]  Request Paper

14. Wall EM, Milne K, Martin ML, Watson PH, Theiss P, Nelson BH. Spontaneous mammary tumors differ widely in their inherent sensitivity to adoptively transferred T cells. Cancer Res. 67(13):6442-50. (2007).
     [View Abstract - PubMed 17616705]  Request Paper

15. Yang T, Wall EM, Milne K, Theiss P, Watson P, Nelson BH. CD8+ T Cells Induce Complete Regression of Advanced Ovarian Cancers by an Interleukin (IL)-2/IL-15 Dependent Mechanism. Clin Cancer Res. 13(23):7172-80. (2007).
     [View Abstract - PubMed 18056198]  Request Paper

2006

16. Erkanli A, Taylor DD, Dean D, Eksir F, Egger D, Geyer J, Nelson BH, Stone B, Fritsche HA, Roden RB. Application of Bayesian modeling of autologous antibody responses against ovarian tumor-associated antigens to cancer detection. Cancer Res. 66(3):1792-8. (2006).
     [View Abstract - PubMed 16452240]  Request Paper

17. Erkanli A, Taylor DD, Dean D, Eksir F, Egger D, Geyer J, Nelson BH, Stone B, Fritsche HA, Roden RB. Application of Bayesian modeling of autologous antibody responses against ovarian tumor-associated antigens to cancer detection. Cancer Res. 66(3):1792-8. (2006).
     [View Abstract - PubMed 16452240]  Request Paper

2005

18. Farris SD, Rubio ED, Moon JJ, Gombert WM, Nelson BH, Krumm A. Transcription-induced chromatin remodeling at the C-Myc gene involves a local exchange of histone H2A.Z. J Biol Chem . (2005).
     [View Abstract - PubMed 15878876]  Request Paper

2004

19. Fernandez de Mattos S, Essafi A, Soeiro I, Pietersen AM, Birkenkamp KU, Edwards CS, Martino A, Nelson BH, Francis JM, Jones MC, Brosens JJ, Coffer PJ, Lam EW. FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism. Mol Cell Biol 24(22):10058-71. (2004).
     [View Abstract - PubMed 15509806]  Request Paper

20. Nelson BH. IL-2, regulatory T cells, and tolerance. J Immunol 172(7):3983-8. (2004).
     [View Abstract - PubMed 15034008]  Request Paper

21. Teague RM, Tempero RM, Thomas S, Murali-Krishna K, Nelson BH. Proliferation and differentiation of CD8+ T cells in the absence of IL-2/15 receptor beta-chain expression or STAT5 activation. J Immunol 173(5):3131-9. (2004).
     [View Abstract - PubMed 15322173]  Request Paper

2003

22. Moon JJ, Rubio ED, Martino A, Krumm A, Nelson BH. A permissive role for phosphatidylinositol 3-kinase in the Stat5-mediated expression of cyclin D2 by the interleukin-2 receptor. J Biol Chem . (2003).
     [View Abstract - PubMed 14660677]  Request Paper

23. Nelson BH, Martyak TP, Thompson LJ, Moon JJ, Wang T. Uncoupling of promitogenic and antiapoptotic functions of IL-2 by Smad-dependent TGF-beta signaling. J Immunol 170(11):5563-70. (2003).
     [View Abstract - PubMed 12759434]  Request Paper

24. Stone B, Schummer M, Paley PJ, Thompson L, Stewart J, Ford M, Crawford M, Urban N, O'Briant K, Nelson BH. Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q. Int J Cancer 104(1):73-84. (2003).
     [View Abstract - PubMed 12532422]  Request Paper

2002

25. Cheng LE, Ohlen C, Nelson BH, Greenberg PD. Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell death. Proc Natl Acad Sci U S A 99(5):3001-6. (2002).
     [View Abstract - PubMed 11867736]  Request Paper

26. Nelson BH. Interleukin-2 signaling and the maintenance of self-tolerance. Curr Dir Autoimmun 5:92-112. (2002).
     [View Abstract - PubMed 11826762]  Request Paper

2001

27. Martino A, Holmes JH 4th, Lord JD, Moon JJ, Nelson BH. Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2. J Immunol 166(3):1723-9. (2001).
     [View Abstract - PubMed 11160217]  Request Paper

28. Moon JJ, Nelson BH. Phosphatidylinositol 3-kinase potentiates, but does not trigger, T cell proliferation mediated by the IL-2 receptor. J Immunol 167(5):2714-23. (2001).
     [View Abstract - PubMed 11509615]  Request Paper

29. Stone B, Schummer M, Paley PJ, Crawford M, Ford M, Urban N, Nelson BH. MAGE-F1, a novel ubiquitously expressed member of the MAGE superfamily. Gene 267(2):173-82. (2001).
     [View Abstract - PubMed 11313144]  Request Paper

2000

30. Gu H, Maeda H, Moon JJ, Lord JD, Yoakim M, Nelson BH, Neel BG. New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway. Mol Cell Biol 20(19):7109-20. (2000).
     [View Abstract - PubMed 10982827]  Request Paper

31. Lord JD, McIntosh BC, Greenberg PD, Nelson BH. The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5. J Immunol 164(5):2533-41. (2000).
     [View Abstract - PubMed 10679091]  Request Paper

1999

32. Evans LS, Witte PR, Feldhaus AL, Nelson BH, Riddell SR, Greenberg PD, Lupton SD, Jones LA. Expression of chimeric granulocyte-macrophage colony-stimulating factor/interleukin 2 receptors in human cytotoxic T lymphocyte clones results in granulocyte-macrophage colony-stimulating factor-dependent growth. Hum Gene Ther 10(12):1941-51. (1999).
     [View Abstract - PubMed 10466628]  Request Paper

33. Hunt AE, Lali FV, Lord JD, Nelson BH, Miyazaki T, Tracey KJ, Foxwell BM. Role of interleukin (IL)-2 receptor beta-chain subdomains and Shc in p38 mitogen-activated protein (MAP) kinase and p54 MAP kinase (stress-activated protein Kinase/c-Jun N-terminal kinase) activation. IL-2-driven proliferation is independent of p38 and p54 MAP kinase activation. J Biol Chem 274(11):7591-7. (1999).
     [View Abstract - PubMed 10066828]  Request Paper

1998

34. Ferrag F, Pezet A, Chiarenza A, Buteau H, Nelson BH, Goffin V, Kelly PA. Homodimerization of IL-2 receptor beta chain is necessary and sufficient to activate Jak2 and downstream signaling pathways. FEBS Lett 421(1):32-6. (1998).
     [View Abstract - PubMed 9462834]  Request Paper

35. Greenberg PD, Finch RJ, Gavin MA, Kalos M, Lewinsohn DA, Lonergan M, Lord JD, Nelson BH, Ohlen C, Sing AP, Warren EH, Yee C, Riddell SR. Genetic modification of T-cell clones for therapy of human viral and malignant diseases. Cancer J Sci Am 4 Suppl 1:S100-5. (1998).
     [View Abstract - PubMed 9619278]  Request Paper

36. Lord JD, McIntosh BC, Greenberg PD, Nelson BH. The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc. J Immunol 161(9):4627-33. (1998).
     [View Abstract - PubMed 9794391]  Request Paper

37. Nelson BH, Willerford DM. Biology of the interleukin-2 receptor. Adv Immunol 70:1-81. (1998).
     [View Abstract - PubMed 9755337]  Request Paper

1997

38. Iversen PO, Hercus TR, Zacharakis B, Woodcock JM, Stomski FC, Kumar S, Nelson BH, Miyajima A, Lopez AF. The apoptosis-inducing granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R functions through specific regions of the heterodimeric GM-CSF receptor and requires interleukin-1β-converting enzyme-like proteases. J Biol Chem 272(15):9877-83. (1997).
     [View Abstract - PubMed 9092524]  Request Paper

39. Nelson BH, Greenberg PD. The Interleukin-2 Receptor. In: Encyclopedia of Immunology 2nd Edition, Eds. P.J. Delves and I. Roitt. Academic Press. (1997).
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40. Nelson BH, McIntosh BC, Rosencrans LL, Greenberg PD. Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor γ(c) chain for Janus kinase activation leading to T cell proliferation. Proc Natl Acad Sci U S A 94(5):1878-83. (1997).
     [View Abstract - PubMed 9050873]  Request Paper

41. Reichel M, Nelson BH, Greenberg PD, Rothman PB. The IL-4 receptor alpha-chain cytoplasmic domain is sufficient for activation of JAK-1 and STAT6 and the induction of IL-4-specific gene expression. J Immunol 158(12):5860-7. (1997).
     [View Abstract - PubMed 9190938]  Request Paper

42. Soto JG, Nelson BH, Weisblat DA. A leech homolog of twist: evidence for its inheritance as a maternal mRNA. Gene 199(1-2):31-7. (1997).
     [View Abstract - PubMed 9358036]  Request Paper

1996

43. Nelson BH, Lord JD, Greenberg PD. A membrane-proximal region of the interleukin-2 receptor γ c chain sufficient for Jak kinase activation and induction of proliferation in T cells. Mol Cell Biol 16(1):309-17. (1996).
     [View Abstract - PubMed 8524310]  Request Paper

1994

44. Greenberg PD, Nelson B, Gilbert M, Sing A, Yee C, Jensen M, Riddell SR. Genetic modification of T cell clones to improve the safety and efficacy of adoptive T Cell therapy. London: CIBA Foundation Symposium #187, pp. 443-54. (1994).
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45. Nelson BH, Lord JD, Greenberg PD. Cytoplasmic domains of the interleukin-2 receptor β and γchains mediate the signal for T-cell proliferation. Nature 369(6478):333-6. (1994).
     [View Abstract - PubMed 7514277]  Request Paper

1993

46. Greenberg PD, Gilbert M, Nelson B, Nagoya S, Yee C, Finch L, Walter B, Riddell SR. Adoptive therapy of human viral disease with virus-specific CD8+ cytolytic T cell clones. In:Cytokine Induced Tumor Immunogenicity, Eds. G. Forni, R. Foa, A. Santoni and L. Frati. Academic Press, pp 212-228. (1993).
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1992

47. Nelson BH, Weisblat DA. Cytoplasmic and cortical determinants interact to specify ectoderm and mesoderm in the leech embryo. Development 115(1):103-15. (1992).
     [View Abstract - PubMed 1638974]  Request Paper

1991

48. Hasan SJ, Nelson BH, Valenzuela I, Keirstead HS, Shull SE, Ethell DW, Steeves JD. Functional repair of transected spinal cord in embryonic chick. Restorative Neurology and Neuroscience 2: 137-154 (1991).
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49. Nelson BH, Weisblat DA. Conversion of ectoderm to mesoderm by cytoplasmic extrusion in the leech embryo Science 253:435-438 (1991).
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