Dr. Andrew P. Weng, MD, PhD
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Dr. Andrew P. Weng, MD, PhD
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Research Interest :
My research focuses on signal transduction via the Notch receptor in lymphoid cells. Notch signaling plays an important role in directing lymphoid progenitors towards T cell fate, and when dysregulated leads to transformation of immature T cells and the development of T-cell acute lymphoblastic leukemia/lymphoma (T-ALL). By modulating Notch signals both in normal lymphoid development and in established human and mouse T-ALL tumors, we have been investigating molecular events responsible for cell fate determination and oncogenic transformation. Many of our findings have direct relevance to the development of rational therapies in the treatment of T-ALL.
More Information:
Visit Dr. Weng's page on the Terry Fox Laboratory Website for publication list, lab members, and other details.