Skip to content. | Skip to navigation


Personal tools

Timon P. H. Buys, PhD

Graduate Student Alumni (Currently Project Manager with Drs. MacAulay and Follen)

TimonBuys


tbuys@bccrc.ca   10th floor - 675 W.10th Avenue, Vancouver, BC, V5Z1L3, Canada


Training

  • BSc (Cell Biology and Genetics), University of British Columbia, 2001

  • PhD (Pathology and Laboratory Medicine), University of British Columbia, 2009


Research Interests

     My primary focus here at the BCCRC is looking for distinct genetic signatures predicting outcome and drug response for a variety of different cancer types (primarily lung cancer). This kind of work represents a key step towards personalized medicine (pharmacogenomics) and elimination of drug resistant tumor recurrence, greatly improving patient survival rates. 


Publications

  • Garnis C, Chari R, Buys TPH, Zhang L, Ng RT, Rosin MP, Lam WL (2009) Genomic imbalances in precancerous tissues signal oral cancer risk, Molecular Cancer, 8:50

  • Buys TPH, Aviel-Ronen S, Waddell TK, Lam WL and Tsao MS. (2009) Defining genomic alteration boundaries for a combined small cell and non-small cell lung carcinoma, J Thorac Oncol, 4:227-39.

  • Campbell JM, Lockwood WW, Buys TPH, Chari R, Coe BP, Lam S, and Lam WL (2008) Integrative genomic and gene expression anlysis of chromosome 7 identified novel oncogene loci in non-small cell lung cancer, Genome, 51:1032-9.

  • Buys TPH, Lam WL (2008) ``Malignancy-associated changes`` in Encyclopedia of Cancer, 2nd Edition (Schwab M, ed.), pp. 1748-1749 (ISBN: 9783540368472).

  • Tsui IFL, Chari R, Buys TPH, Lam WL (2007) Public Databases and Software for the Pathway Analysis of Cancer Genomes, Cancer Informatics, 3:389-407.

  • Buys TPH, Wilson IM, Coe BP, Lee EHL, Kennett JY, Lockwood WW, Tsui IFL, Shadeo A, Chari R, Garnis C, Lam WL (2007) `Detailed Comparisons of Cancer Genomes` in Comparative Genomics: Fundamental and Applied Perspectives (Brown JR, ed.), CRC Press / Taylor and Francis, LLC. Boca Raton, FLA, pp. 245-259 (ISBN: 9780849392160).

  • Buys TPH, Wilson IM, Coe BP, Lockwood WW, Davies JJ, Chari R, DeLeeuw RJ, Shadeo A, MacAulay C, Lam WL (2007) `Key Features of BAC Array Production and Usage` in DNA Microarrays (Methods Express Series) (Schena M, ed.), Scion Publishing, Ltd. Bloxham, Oxfordshire, UK, pp.115-145 (ISBN: 9781904842156).

  • Stratford AL, Habibi G, Astanehe A, Jiang H, Hu K, Park E, Shadeo A, Buys TPH, Lam W, Pugh T, Marra M, Nielsen TO, Klinge U, Mertens PR , Aparicio S and Dunn SE (2007) Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer providing a potential target for therapy, Breast Cancer Research, 9:R61.

  • Buys TPH, Chari R, Lee EHL, Zhang M, MacAulay C, Lam S, Lam WL, Ling V. (2007) Genetic changes in the evolution of multidrug resistance for cultured human ovarian cancer cells, Genes, Chromosomes and Cancer, 46:1069-1079.

  • Garnis C, Davies JJ, Buys TP, Tsao MS, Macaulay C, Lam S, Lam WL. (2005) Chromosome 5p aberrations are early events in lung cancer: implication of glial cell line-derived neurotrophic factor in disease progression, Oncogene, 24:4806-12.

  • Garnis C, Buys TP, Lam WL (2004) Genetic Alteration and Gene Expression Modulation During Cancer Progression, Molecular Cancer, 3, 9:1-23.

 


Links

| BCCA | BCCRC | Integrative Oncology | Cancer Genetics | Wan Lam Lab |