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David Rowbotham

Graduate Student

David Rowbotham


drowbotham@bccrc.ca   10th floor - 675 W.10th Avenue, Vancouver, BC, V5Z1L3, Canada


Training

  • Summer Student, BC Cancer Research Centre, Vancouver, BC, Canada, 2014
  • B.Sc. (Biochemistry and Microbiology), University of Victoria, Victoria, BC, Canada, 2014
  • Summer Studentship, BC Cancer Research Centre, Vancouver, BC, Canada, 2013
  • Co-op Research Student, BC Cancer Research Centre, Vancouver, BC, Canada, Sep 2012 - Apr 2013
  • First year general science, University of Western Ontario, London, ON, Canada, Sep 2008 - Apr 2009


Program 


Research Interests

  • Lung cancer biology in non-smokers
  • micro RNAs in lung cancer
  • long non-coding RNAs in lung cancer
  • Epigenetics
  • Bioinformatics

Publications

Journal Articles

  • Martinez VD, Enfield KSS, Rowbotham DA, Lam WL (2015) An atlas of gastric PIWI-Interacting RNA transcriptomes and their utility for identifying signatures of gastric cancer recurrence. Gastric Cancer. In press. [PMID:25779424]
  • Rowbotham DA, Marshall EA, Vucic EA, Kennett JY, LamWL, Martinez VD (2014) DNA methylation changes and aging. Journal of Aging Science 3 (1): 1000130, 1-9.

  • Rowbotham DA, Enfield KSS, Martinez VD, Thu KL Vucic EA, Stewart GL,  Bennewith KL, Lam WL (2014) Multiple components of the VHL tumor suppressor complex are frequently affected by DNA copy number losses in pheochromocytoma. International Journal of Endocrinology 2014: 546347, 1-9. [PMID:25298778] 

  • Wilson IM*, Vucic EA*, Enfield KSS, Thu KL, Zhang Y-A, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TPH, Selamat SA, Laird-Offinga I, Liu P, Anderson M, You M, Tsao-MS, Brown CJ, Bennewith KL, MacAulay CE, Karsan A, Gazdar AF, Lam S, Lam WL (2014) EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk. Oncogene33(36):4464-7. [PMID: 24096489]
  • Hubaux R*, Martinez VD*, Rowbotham D, Lam WL (2014) Comparative Genomic Hybridization and Array based CGH in Cancer.  In Molecular testing in cancer. George M. Yousef and Serge Jothy ed. Springer, pp. 27-37.
  • Hubaux R*, Becker-Santos DD*, Enfield KSS, Rowbotham D, Lam S, Lam WL, Martinez VD (2013) Molecular features in arsenic induced lung tumors. Molecular Cancer 12:20, 1-11. [PMID:23510327]

Abstracts

  • Enfield KSS, Ramnarine VR, Rowbotham DA, Lam S, Lam WL (2013) MicroRNA deregulation associated with node positive lung adenocarcinoma. World Conference of Lung Cancer. Sydney, Australia.
  • Enfield KSS, Rowbotham DA, Becker-Santos DD, Chari R, Fuller M, Zhang M, Suzuki M, MacAulay CE, Karsan A, Lam S, Lam WL (2013) ELF3 is a novel oncogene frequently activated by genetic and epigenetic mechanisms in lung adenocarcinoma. World Conference of Lung Cancer. Sydney, Australia.
  • Enfield KSS, Ramnarine VR, Rowbotham DA, Lam S, Lam WL (2013) Deregulation of microRNAs associated with node positive lung adenocarcinoma. BC Cancer Agency Research Day. Vancouver, BC.
  • Enfield KSS, Ramnarine VR, Rowbotham DA, Lam S, Lam WL (2013) Deregulation of microRNAs associated with node positive lung adenocarcinoma. Bioinformatics and Oncology Research Day. Vancouver, BC.
  • Enfield KSS, Ramnarine VR, Rowbotham DA, Lam S, Lam WL (2013) MicroRNA deregulation associated metastasis and recurrence of non-small cell lung cancer. AACR-JCA Breakthroughs in Translational Research. Maui, HI.
  • Rowbotham D, Enfield KSS, Chari R, Becker-Santos D, Lam S, Lam WL (2012) ELF3, a fetal lung transcription factor, is frequently re-activated in lung adenocarcinoma. BC Annual Conference. Vancouver, BC.

Awards

  • Faculty of Science Entrance Scholarship, University of Western Ontario, 2007
  • BC Cancer Summer Studentship, 2013
  • Interdisciplinary Oncology Program Entrance Scholarship, University of British Columbia, 2014

Links

| BCCA | BCCRC | Integrative Oncology | Cancer Genetics | Wan Lam Lab |