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Pierre Lane, Ph.D, P.Eng

Research Scientist - Imaging Unit, Integrative Oncology


BC Cancer Research Centre

Imaging Unit, Integrative Oncology

Room 6-122 (office), 5-208 (lab)

675 West 10th Avenue

Vancouver, BC V5Z 1L3


Tel. (604) 675-8087, Fax (604) 675-8099



Pierre Lane 160X200

Research Website

Optical Cancer Imaging Lab



Research Scientist, Integrative Oncology, BC Cancer Research Centre

Adjunct Professor, Electrical and Computer Engineering, Univeristy of British Columbia

Adjunct Professor, Biomedical and Physiology and Kinesiology, Simon Fraser University



Ph.D, Electrical and Computer Engineeringing, Dalhousie University (Halifax, NS), 1999

M.Eng, Electrical Engineering, Technical University of Nova Scotia (Halifax, NS), 1996

B.Eng and Mgmt, Engineering Physics, McMaster University (Hamilton, ON), 1993


Brief Bio

Dr. Lane was a Post-Doctoral Fellow at the BC Cancer Research Center (BCCRC) from 1999 to 2001 and has been involved with the commercialization of several optical technologies developed during that time. From 2001 to 2002 he was a Research Scientist at Digital Optical Imaging Corp. where he led the design effort for a confocal microendoscope for early cancer detection. He is currently a Scientist at the BCCRC, an adjunct professor at the University of British Columbia and Simon Fraser University, and a consultant in the fields of optics and biophotonics. His research interests include fluorescence and reflectance imaging for early detection of cancer, optical signal and image processing, fiber optics, biophotonics, confocal microscopy, spectroscopy, optical coherence tomography (OCT), and spatial light modulation. He is a member of the IEEE, OSA, SPIE, and is a professional engineer registered in the province of British Columbia.


Publications - Last 5 years

  1. Lee AMD, MacAulay C, Lane P.  Depth-multiplexed optical coherenece tomography dual-beam manually-actuated distortion-corrected imaging (DMDI) with a micrometer catheter.  Biomed Opt Express.  2018 Oct 23;9(11):5678-5690.
  2. Abouei E, Lee AMD, Pahlevaninezhad H, Hohert G, Cua M, Lane P, Lam S, MacAulay C.  Correction of motion artifacts in endoscopic optical coherence tomography and autofluorescence images based on azimuthal en face image registration.J Biomed Opt. 2018 Jan; 23(1):1-13
  3. Lee AMD, Hohert G, Angkiriwang PT, MacAulay C, Lane P.  Dual-beam manually-actuated distortion-corrected imaging (DMDI) with micromotor catheters.  2017 Sep 4; 25(18):22164-22177
  4. Bodenschatz N, Poh CF, Lam S, Lane P, Guillaud M, MacAulay CE. Dual-mode endomicroscopy for detection of epithelial dysplasia in the mouth: a descriptive pilot study.  J Biomed Opt. 2017 Aug; 22(8)1-10
  5. Schlosser C, Bodenschatz N, Lam S, Lee M, McAlpine JN, Miller DM, Van Niekerk DK, Follen M, Guillaud M, MacAulay CE, Lane PM.  Fluorescence confocal endomicroscopy of the cervix: pilot study on the potential and limitations for clinical implementation. J Biomed Opt.  2016 Dec 1;21)12_:126011
  6. Pahlevaninezhad H, Lee AM, Hohert G, Lam S, Shaipanich T, Beaudoin EL, MacAulay C, Boudoux C, Lane PM. Endoscopic high-resolution autofluorescence imaging and OCT of pulmonary vascular networks.  Opt Lett.  2016 Jul 14; 41(14):3209-12
  7. Kirby M, Lane PM, Coxson H. Measurement of pulmonary structure and function (Book Chapter), Barr, Graham; Parr, David; Vogel-Claussen, Jens (Ed.): Imaging, (70), Chapter 14, pp. 216-232, European Respiratory Society, 2016
  8. Sheikhzadeh F, Ward RK, Carraro A, Chen ZY, van Niekerk D, Miller D, Ehlen T, MacAulay CE, Follen M, Lane PM, Guillaud M. Quantification of confocal fluorescence microscopy for the detection of cervical intraepithelial neoplasia.  Biomed Eng Online.  2015 Oct24;14:96
  9. Pahlevaninezhad H, Lee AMD, Ritchie A, Shaipanich T, Zhang W, Ionescu DN, Hohert G, MacAulay C, Lam S, Lane P.   Endoscopic Doppler optical coherence tomography and autofluorescence imaging of peripheral pulmonary nodules and vasculature.  Biomedical Optics Express.  2015 Sept 30;6(10):4191-9
  10. Kirby M, Ohtani K, Nickens T, Lopez Lisbona RM, Lee AMD, Shaipanich T, Lane PM, MacAulay C, Lam S, and Coxson HO. Reproducibility of Optical Coherence Tomography Airway Imaging. Biomed Opt Express.  2015 Oct 14;6(11):4365-77
  11. Kirby M, Ohtani K, Lopez Lisbona RM, Lee AM, Zhang W, Lane PM, Carfolomevqa N, Hui L, Ionescu D, Coxon HO, MacAulay C, FitzGerald JM, Lam S.  Bronchial thermoplasty in asthma: 2-year follow-up using optical coherence tomography.  Eur Respir J.  46(3):859-62 2015.
  12. Lee AMD, Cahill L, Liu K, MacAulay C, Poh C, Lane PM.  Wide-field in vivo oral OCT imaging.  Biomedical Optics Express.  6(7):2664-74. 2015.
  13. Pahlevaninezhad H, Lee AM, Rosin M, Sun I, Zhang L, Hakimi M, MacAulay C, Lane PM.  Optical coherence tomography and autofluorescence imaging of human tonsil.  PLoS One.  2014 Dec 26;9(12):e1158893
  14. Pahlevaninezhad H, Lee AMD, Shaipanich T, Raizada R, Cahill L, Hohert G, Yang VXD, Lam S, MacAulay C, Lane PM.  A high-efficiency fiber-based imaging system for co-registered autofluorescence-optical coherence tomography (AF-OCT). Biomed Opt Express.  2014 Aug 6;5(9):2978-87
  15. Lee AMD, Kirby M, Ohtani K, Candido T, Shalansky R, MacAulay C, English J, Finley R, Lam S, Coxson HO, Lane P.  Validation of airway wall measurements by optical coherence tomography in porcine airways. PLoS ONE 9(6): e100145. doi:10.1371/journal.pone.0100145.
  16. Lee AMD, Pahlevaninezhad H, Yang VXD, Lam S, MacAulay C, Lane PM. Fiber-optic polarization diversity detection for rotary probe optical coherence tomography.  Optics Letters v.39 (12) 3638-3641 (2014).
  17. Vuong B, Lee AMD, Luk TWH, Sun C, Lam S, Lane PM, Yang VXD. High speed, wide velocity dynamic range Doppler optical coherence tomography (Part IV): split spectrum processing in rotary catheter probes. Optics Express v.22(7), April 2014.
  18. Wang L, Lee JS, Lane PM, Serachitopol D, Atkinson EN, Follen M, MacAulay C, Cox DD. A statistical model for removing inter-device differences in spectroscopy. Optics Express v.22(7), April 2014.
  19. Pahlevaninezhad H, Lee AMD, Lam S, MacAulay C, Lane PM. Coregistered autofluorescence-optical coherence tomography (AF-OCT) imaging of human lung sections.  Journal of Biomedical Optics v.19(3):036022, March 2014.
  20. Contaldo M, Poh CF, Guillaud M, Lucchese A, Rullo R, Serpico R, Lam SF, MacAulay C, Lane PM.  Oral mucosa optical biopsy by a novel handheld fluorescent confocal microscope specifically developed: technologic improvements and future prospects. Oral surgery, oral medicine, oral pathology and oral radiology, 116(6) 752-8, Dec 2013.
  21. Pahlevaninezhad H, Cecic I, Lee AMD, Kyle AH, Lam S, MacAulay C and Lane PM.  Multimodal tissue imaging: using coregistered optical tomography data to estimate tissue autofluorescence intensity change due to scattering and absorption by neoplastic epithelial cells.  Journal of Biomedical Optics, v. 18(10), 106007, October 2013.
  22. Lee AMD, Ohtani K, MacAulay CE, McWilliams A, Shaipanich T , Yang VXD, Lam S, Lane PM. In vivo Lung Microvasculature Visualized in 3-Dimensions using Fiber-Optic Color Doppler Optical Coherence Tomography. Journal of Biomedical Optics, v. 18(5), 050501, 2013.
  23. El Hallani S, Poh CF, MacAulay CE, Follen M, Guillaud M, Lane PM. Ex vivo Confocal Imaging with Contrast Agents for the Detection of Oral Potentially Malignant Lesions. Oral Oncology, v. 49(6) p. 582-590, 2013.