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Dr. Judy Wong, Ph.D

Associate Member

Refereed Journals

1. Wong JMY and Collins K. Telomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenita. Genes Dev. 20(20) 2848-58. (2006)
2. Fleisig HB and Wong JM. Telomerase as a clinical target: current strategies and potential applications. Exp Gerontol. 42(1-2):102-12. (2007)
3. Errington TM, Fu D, Wong JMY and Collins K. Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference. Mol Cell Biol. 28(20):6510-20. (2008)
4. Savage SA, Dokal I, Armanios M, Aubert G, Cowen EW, Domingo DL, Giri N, Greene MH, Orchard PJ, Tolar J, Tsilou J, Van Waes C, Wong JMY, Young NS, Alter BP. Dyskeratosis Congenita: The First NIH Clinical Research Workshop. Pediatric Blood and Cancer 53(3):520-3. (2009)
5. Trudeau MA and Wong, JM. Genetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies. Curr. Pharmacogenomic Person Med. 8(1):7-24. (2010)
6. Tamakawa RA, Fleisig HB and Wong JMY. Telomerase inhibition potentiates the effects of genotoxic agents in breast and colorectal cancer cells in a cell cycle specific manner. Cancer Res 70:8684-94. (2010)
7. Fleisig HB and Wong JMY. Telomerase promotes efficient cell cycle kinetics and confers growth advantage to telomerase-negative transformed human cells. Oncogene 31(8):954-65. (2012)
8. Zeng XL, Thumati NR, Fleisig HB, Hukezalie, KR, Savage SA, Giri N, Alter BP and Wong JMY. The accumulation and not the specific activity of telomerase ribonucleoprotein determines telomere maintenance deficiency in X-linked dyskeratosis congenita. Hum Mol Genet 21(4):721-9. (2012)
9. Fleisig H, Wong J. Measuring cell cycle progression kinetics with metabolic labelling and flow cytometry. J Vis Exp 63.pil:4045. (2012)
10. Hukezalie KR, Thumati NR, Cote H and Wong JMY. In vitro and ex vivo effects of anti-HIV nucleoside and non-nucleoside reverse transcriptase inhibitors on cellular telomerase activities. PLoS One. 7(11): e47505. doi:10.1371/journal.pone.0047505. (2012)

 

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