Dr. Hui Xue, MD, Ph.D
Research and Laboratory Technician
hxue@bccrc.ca
Tel: 604-675-8000 ext. 7013
Fax: 604-675-8183
Research Interests:
My current research efforts are 1) to develop living tumor lines from primary tumors arisen in ovary, skin, pancreas and a few other organs of patients; 2) to maintain transplantable living tumor lines at the Living Tumor Laboratory; and 3) to apply the models in discovery and drug development, particularly in the area of ovarian cancer.
At the Living Tumor Laboratory, we have developed 30 transplantable ovarian tumor lines. All the tumor lines maintain high similarity with the original patients' tumors in terms of histopathology, genetic and epigenetic characteristics. Importantly, xenografts of the tumor lines retain biological properties of the tumors observed in the clinic (e.g. tissue invasion/metastasis and drug sensitivities). The tumor lines are well validated, and each tumor line generation is stored in liquid
