Skip to content. | Skip to navigation


Personal tools

Dr. Donald Yapp, Ph.D

Research Scientist


people_dyapp.jpg

 

dyapp@bccrc.ca

Tel: 604-675-8023

Fax: 604-675-8183

675 West 10th Avenue, Vancouver, BC, V5Z 1L3

 

Research Role:

 

Education:

  • Ph.D (Chemistry), University of Victoria, 1993 
  • B.Sc. (Chemistry), University of Victoria, 1987

 

Research Interest:

  • Tumour biology; non-invasive imaging including PET and MRI


Non-invasive evaluation of changes in the tumour microenvironment (vascularization, oxygenation, and metabolism) that are associated with treatment or molecular changes: 

Our group is interested in understanding how molecular changes in tumours are manifested in their microenvironment, and whether such changes can be monitored non-invasively to guide treatment strategies. We therefore use molecular techniques in a complementary fashion with non-invasive imaging (positron emission tomography and magnetic resonance imaging) to study clinically relevant tumour models from the bottom up and top down. Presently, we have programs examining the effects of HER-2 overexpression on physiological functions and response to treatment in aggressive breast cancer tumours and the effects of liposomal drug treatment on the oxygenation and vascularity of colorectal tumours.

 

Publications


Back to Personnel
Back to Main Page