Parv Chapani
Honours Student
Education:
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BSc., Biochemistry, University of Victoria, Graduate 2015
Advisor: Dr. Brad Nelson
Contact:
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Tel:250-519-5716
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Fax: 250-519-2040
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Email:parv.chapani@bccancer.bc.ca
Research Interests
The immune system plays a key role in clinical outcomes in cancer patients. In particular, the presence of organized intratumoral lymphocytes, tertiary lymphoid structures (TLS), has been associated with survival in breast, colorectal, and other human cancers. Our research aims to initiate the formation of intratumoral TLS in a murine model of breast cancer through the use of oncolytic viruses expressing mCXCL13, a murine B lymphocyte chemoattractant involved in the establishment and organization of TLS. The overall goal of this research is to develop an immunotherapy that will initiate an increased immune response to cancer, thus enhancing the patients' ability to fight cancer.