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Martin Isabelle




Postdoctoral Fellow



Advisor: Dr. Julian Lum



Tel        250-519-5700

Fax       250-519-2040




Research Interests


My current research involves using Raman spectroscopic techniques to understand the radiobiological and cellular changes that take place during cancer radiation treatment. Raman spectroscopy can provide a detailed "biochemical fingerprint" of cells and tissues that allow spectroscopists and clinicians to understand some of the biochemical and structural changes taking place in cancer disease progression as well as in cancer treatment. In the past, Raman spectroscopy has been used in cancer diagnostics for a variety of tumor types but also has the potential to be used as a non-invasive tool for predicting patient response to cancer treatment (e.g. assessing radiosensitivty of particular cancer cells for planning individual patient radiation treatment) or for monitoring ongoing cancer treatment to assess patient's response to treatment. Current work with the group has involved assessing radiobiological changes in cells but we will be progressing to using animal models very soon in order to assess these changes in a tumor tissue microenvironment.


Other Research Interest include:


FTIR and Raman spectrocopy for asessing metastatic status in lymph nodes, Photodynamic therapy (PDT) and dosimetry, singlet oxygen spectroscopy, fluorescence spectroscopy, tumor banking, cancer imaging, spectroscopy and tomography, and virtual pathology and telepathology.


View Publications