Brad Nelson, PhD

			Director, Research Laboratories Distinguished Scientist Adjunct Professor, Biochemistry and Microbiology, UVic Adjunct Associate Professor, Biology, UVic Associate Professor, Medical Genetics, UBC Education B.Sc., University of British Columbia, 1987  Ph.D., University of California at Berkeley, 1991 Lab members Postdoctoral fellows: Julie Nielsen, Ronald de Leeuw, Sally Amos, David Kroeger                               : Pheh Ping Chang,  Kwame Twumasi-Boateng Graduate Students:   Spencer Martin, Sara Kost, Charlotte Lo Undergraduate Students: Jessica Pettigrew Research Assistants:  Katy Milne, Darin Wick                        Contact Tel       250-519-5705 Fax      250-519-2004 Email   bnelson@bccancer.bc.ca

Research Interests

Our lab studies the immune response to cancer with the goal of developing immune-based strategies to prevent, detect and treat cancer. We use clinical specimens and murine models to investigate the complex interaction between the immune system and cancer at distinct stages of disease, including tumour initiation, progression, metastasis and recurrence. In collaboration with other groups, we are developing a clinical trials program to bring novel immunotherapies to patients at our centre.

Specific projects include:

• Use of genomic technologies to map the immune response to breast, prostate, ovarian and lymphoid cancers before, during and after standard therapy

• Development of novel target antigens and immuno-modulatory strategies for vaccine- and cell-based cancer therapies

• Basic studies of cytokine and T cell receptor signal transduction

• Applying immunological approaches to the early detection of cancer

Academic Affiliations

University of Victoria, Department of Biochemisty and Microbiology, and Department of Biology

University of British Columbia, Department of Medical Genetics

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