Voronoi Polygon

• The whole tissue is geometrically divided by the Voronoi diagram.
• A Voronoi polygon corresponds to the "area of influence" of the cell : it reflects its local neighborhood.

Figure 4: Voronoi Polygon [View Image]

• Number of sides of the polygon (Blue):
  Number of neighbor cells (White)
• Area of the polygon :
  Distance from the neighbor cells
• Shape of the polygon :
  Spatial Arrangement of the neighboring cells

Ulam Tree

Figure 5: Ulam Tree [View Image]

• Some local trees, such as the Ulam tree shown in Figure 5, can be used to describe the extended neighborhood of a cell.
• The shape of a tree may give us some information about the underlying growth process giving rise to clone.