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Stephen Lam

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Peer-Reviewed Papers
Peer-Reviewed Papers | Non Peer-Reviewed Papers | Books (and Chapters) | Presentations and Symposium Proceedings | Abstracts | Patents | Other Forms of Publications

    2006

  1. Coe BP, Lee EHL, Chi B, Girard L, Minna JD, Gazdar AF, Lam S, MacAulay C, Lam WL. (2006). Tiling genomic array profiling of small cell lung cancer cell lines identifies highly frequent copy number gains of MAD1L1. Genes Chromosomes Cancer 45: 11-19. (2006).

  2. Coe BP, Lockwood WW, Girard L, Chari R, MacAulay C, Lam S, Gazdar AF, Minna JD, Lam WL. . Differential Disruption of Cell Cycle Pathways in Small Cell and Non-small Cell Lung Cancer. British Journal of Cancer.; 94(12): 1927-1935. (2006).

  3. Coe, BP., Lee, EH., Chi, B., Girard, L., Minna, JD., Gazdar, A., Lam, S., MacAulay, C., Lam, W.L.: . Genes Chromosomes Cancer. Gain of a region on 7p22.3, containing MAD1L1, is the most frequent event in small-cell lung cancer cell lines. 45(1):11-9 (2006).

  4. Cutz J.C., Guan J, Bayani J., Yoshimoto M., Xue H., Sutcliffe M., English J., Flint J., LeRiche J., Yee J., Squire J. A., Gout P. W., Lam S. and Wang YZ. . Establishment in SCID Mice of Subrenal Capsule Xenografts and Transplantable Tumour Lines from a Variety of Primary Human Lung Cancers: Potential Models for Studying Tumour Progression-Related Changes. Clinical Cancer Research. July 12(13): 4043-4054 (2006).

  5. Garnis C, Lockwood WW, Vucic E, Ge Y, Girard L, Minna JD, Gazdar AF, Lam S, MacAulay C, Lam WL. . (2006) Comparing canonical non-small cell lung squamous and adenocarcinoma model genomes. International Journal of Cancer. 118: 1556-1564. (2006).

  6. Lam S, McWilliams A, Leriche J, MacAulay C, Wattenburg L, Szabo E. . A Phase I Study of Myo-inositol for Lung Cancer Chemoprevention. Cancer Epidemiology Biomarkers and Prevention. August; 15(8): 1526-1531. (2006).

  7. Lonergan, K., Chari, R., deLeeuw, R., Shadeo, A., Chi, B., Tsao, MS., Jones, S., Marra, M., Ling, V., Ng, R., MacAulay, M., Lam, S., Lam, W. . Identification of novel lung genes in bronchial epithelium by serial analysis of gene expression. Am J Respir Cell Mol Biol. Dec; Vol 35 (6), 651-61. (2006).

  8. Malhotra S, Lam S, Man Paul SF, Gan Wen Qi, Sin Don D. . The Relationship Between STAGE 1 AND 2 Non-Small Cell Lung Cancer And Lung Function In Men and Women BMC Pulm Med Feb 1: 6:2 (2006).

  9. McWilliams AM, Mayo JR, Ahn MI, MacDonald SLS, Lam S. . Lung Cancer Screening Using Multi-Slice Thing-Section Computed Tomography and Autofluorescence Bronchoscopy. Journal of Thoracic Oncology. 1(1):61-6 (2006).

  10. Shaipanich T, McWilliams A, Lam S. . Early Detection and Chemoprevention of Lung Cancer. Respirology. July ; 11(4): 366-372. (2006).

  11. Sin DD, Man Paul SF, McWilliams A, Lam S.. Progression of Airway Dysplasia and C-reactive Protein in Smokers at High Risk of Lung Cancer. Respiratory and Critical Care Medicine. Mar 1; 173(5): 535-9. Epub 2005 (2006).

    12. 2005

  12. Coe BP, Henderson LJ, Garnis C, Tsao M-S, Gazdar A, Minna J, Lam S, MacAulay C, Lam WL. . High resolution chromosome 5p array CGH analysis of small cell lung carcinoma cell lines. Genes Chromosomes and Cancer. 42(3): p. 308-313 (2005).

  13. Garnis C et al. . Chromosome 5p aberrations and glial cell line-derived neurotrophic factor activation are early events in lung cancer. Oncogene. 24:(30): 4806-12 (2005).

  14. Garnis C, Campbell J, Davies JJ, Lam S, MacAulay C, Lam WL. . Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis. Hum Mol Genet;14(4)475-482 (2005).

  15. Garnis C, et al. . High resolution analysis of non-small cell cancer cells line by whole genome tiling path array CGH. Int J Cancer. Sep 26 [Epub ahead of print] (2005).

  16. Guillaud M, leRiche J, Daw C, Korbelik J, Coldman A, Wistuba I, Park IW, Fazdar A, Lam S, MacAulay C. . Nuclear morphometry as a Biomarker for Bronchial Intraepithelial Neoplasia: Correlation with Genetic Damage and Cancer Development. Cytometry Part A (1):34-40, (2005).

  17. Henderson LJ, Coe BP, Lee E, Girard L, Gazdar AF, Minna JD, Lam S, MacAulay C, Lam WL. . Genomic and gene expression profiling of minute alterations of chromosome arm 1p in small-cell lung carcinoma cells. Brit J Cancer. 92(8):p. 1553-60 (2005).

  18. Tichelaar JW, Zhang Y, leRiche JC, Biddinger PW, Lam S, Anderson MW. . Increased staining for phosopho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsies. BMC Cancer, 5:155. 06 Dec (2005).

    19. 2004

  19. Garnis C, MacAulay C, Lam S, Lam WL. . Genetic alteration on 8q distinct from MYC in bronchial carcinoma in-situ lesions. Lung Cancer;44:403-404 (2004).

  20. Lam S, leRiche JC, McWilliams A, MacAulay C, DYachkova Y, Szabo E, Mayo J, Schellenberg R, Coldman A, Hawk E, Gazdar AF. A randomized phase IIb trial of Pulmicort Turbuhaler (Budesonide) in persons with dysplasia of the bronchial epithelium. Clin Cancer; 10:6502-6511 (2004).

  21. Zeng H, McWilliams A, Lam S. . Optical spectroscopy and imaging for early lung cancer detection: a review. Photodiagnosis and Photodynamic Therapy;1:111-122 (2004).

  22. Zeng H, Petek M, Zorman MT, McWilliams A, Palcic B, Lam S. . Integrated endoscopy system for simultaneous imaging and spectroscopy for early lung cancer detection Optics Letters 29: 587-589 (2004).

    23. 2003

  23. Huang Z, McWilliams A, Lam S, Mclean DI, Lui H, Zeng H. . Near-infrared Raman Spectroscopy for Optical Diagnosis of Lung Cancers Int J Cancer 107(6):1047-1052 (2003).

  24. Huang Z, McWilliams A, Lam, S English J, McLean DI, Lui H, Zeng H. Effect of formalin fixation on the near-infrared Raman spectroscopy of normal and cancerous human bronchial tissues Int J Oncol 23(3):649-656 (2003).

  25. Lam S, Xu XC, Parker-Klein H, leRiche JC, MacAulay C, Guillaud M, Coldman A, Gazdar A, Lotan R. Surrogate endpoint biomarker analysis in a retinol chemoprevention trial in current and former smokers with bronchial dysplasia Int J Oncol 23:1607-1613 (2003).

  26. MacAulay C, Lonergan K, Chi B, Tsao M, Marra M, Lam S, Lam W. . Serial Analysis of Gene Expression Profiles of Developmental Stages in Non-Small Cell Lung Carcinoma CHEST (supp) (2003).

  27. McWilliams A, Mayo J, MacDonald S, leRiche J, Palcic B, Szabo E, Lam S. Lung Cancer Screening: A Different Paradigm Am J Respir Crit Care Med 168:1167-1178 (2003).

  28. Sun XR, Zheng Y, MacAulay C, Lam S, Doudkine A, Palcic B. In Vitro Model for Studying Malignancy-Associated Changes Analytical Cellular Pathology 25(2):95-102 (2003).

  29. Tsao AS, McDonnell T, Lam S, Putnam JB, Bekel N, Hong WK, Kurie JM. Increase phospho-AKT (Ser473) expression in bronchial dysplasia: Implications for lung cancer prevention studies Cancer Epidemiol Biomarkers Prev 12:660-664 (2003).

  30. ZÖchbauer-MÜller S, Lam S, Toyooka S, Virmani AK, Toyooka KO, Seidl S, Minna JD, Gazdar AF. Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers Int J Cancer 107:612-616 (2003).

    31. 2002

  31. Field JK, Brambilla C, Caporaso N, Flahault A, Henschke C, Herman J, Hirsch F, Lachmann P, Lam S, Maier S, Montuenga LM, Mulshine J, Murphy M, Pullen J, Spitz M, Tockman M, Tyndale R, Wistuba I, Youngson, J. Consensus statements from the 2nd International Lung Cancer Molecular Biomarkers Workshop: A European strategy for developing lung cancer diagnostics in high risk populations Int J Oncol 21:369-373 (2002).

  32. Lam S, MacAulay C, leRiche JC, Dyachkova Y, Coldman A, Guillaud M, Hawk E, Christen MO, Gazdar AF. A randomized phase IIb trial of anethole dithiolethione in smokers with bronchial dysplasia J Natl Cancer Inst 94(13):1001-1009 (2002).

  33. McWilliams A, Lam, S. New approaches to lung cancer prevention Curr Oncol Rep 4:487-494 (2002).

  34. McWilliams A, MacAulay C, Gazdar AF, Lam S. Innovative molecular and imaging approaches for the detection of lung cancer and its precursor lesions Oncogene 21:6949-6959 (2002).

  35. OShaughnessy JA, Kelloff GJ, Gordon GB, Dannenberg AJ, Hong WK, Fabian CJ, Sigman CC, Bertagnolli MM, Stratton SP, Lam S, Nelson WG, Meyskens FL, Alberts DS, Follen M, Rustgi AK, Papadimitrakopoulou V, Scardino PT, Gazdar AF, Wattenberg LW, Sporn MB, Sakr WA, Lippman SM, von Hoff DD. Treatment and prevention of intraepithelial neoplasia: an important target for accelerated new agent development Clin Cancer Res 8:314-346 (2002).

  36. Palcic B, Garner DM, Beveridge J, Sun XR, Doudkine A, MacAulay C, Lam S, Payne PW. Increase of sensitivity of sputum cytology using high-resolution image cytometry: field study results Cytometry (Clinical Cytometry) 50:168-176 (2002).

    37. 2001

  37. Gazdar AF, Zochbauer-Muller S, Virmani A, Kurie J, Minna JD, Lam S. Re: Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas. J Natl Cancer Inst 93(1):67-68 (2001).

  38. Kennedy TC, Lam S, Hirsch FR. Review of recent advances in fluorescence bronchoscopy in early localization of central airway lung cancer. Oncologist 6(3):257-262. (2001).

  39. Zochbauer-Muller S, Fong KM, Maitra A, Lam S, Geradts J, Ashfaq R, Virmani AK, Milchgrub S, Gazdar AF, Minna JD. 5 CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer Cancer Res 61(9):3581-3585 (2001).

    40. 2000

  40. Lam S, Lam B, Petty TL. Early detection of lung cancer: new tools for casefinding. Canadian Family Physician 47:537-544. (2000).

  41. Lam S, MacAulay C, leRiche JC, Palcic B. Detection and Localization of early lung cancer by fluorescence bronchoscopy. Cancer (supp)89:2468-2473 (2000).

  42. Lam S, Yap WS. Early diagnosis of lung cancer. Canadian Journal of Continuing Medical Education, October 187-194. (2000).

  43. Wistuba II, Behrens C, Virmani AK, Mele G, Milchgrub S, Girard L, Fondon JW 3rd, Garner HR, McKay B, Latif F, Lerman MI, Lam S, Gazdar AF, Minna JD. . High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints, Cancer Res;60: 1949-60 (2000).

    44. 1999

  44. Lam S & Palcic B. Re: Autofluorescence Bronchoscopy in the Detection of Squamous Metaplasia in Current and Former Smokers (Correspondence). J Natl Cancer Inst 91:561. (1999).

  45. Lam S & Shibuya H. Early diagnosis of lung cancer. Clinics in Chest Medicine 20:53-61. (1999).

  46. Lam S, leRiche JC, Zheng Y, Coldman A, MacAulay C, Hawk E, Kelloff G, Gazdar AF. Sex-related differences in bronchial epithelial changes associated with tobacco smoking. J Natl Cancer Inst 91:691-696. (1999).

  47. Wistuba II, Behrens C, Virmani AK, Milchgrub S, Syed S, Lam S, Mackay B, Minna JD, Gazdar AF. Allelic losses at chromosome 8p21-23 are early and frequent events in the pathogenesis of lung cancer. Cancer Research 59:1973-1979. (1999).

    48. 1998

  48. Ikeda N, MacAulay C, Lam S, leRiche JC, Payne P, Garner D, Konaka C, Kato H, Palcic B. Malignancy associated changes in bronchial epithelial cells and clinical application as a biomarker. Lung Cancer 19:161-166. (1998).

  49. Lam S & Palcic B. New bronchoscopic approaches for the detection of early lung cancer. Primary Care & Cancer (Supp) 18:17-21. (1998).

  50. Lam S, Kennedy T, Unger M, Miller Y, Gelmont D, Rusch V, Gipe B, Howard D, LeRiche JC, Coldman A, Gazdar AF. Localization of bronchial intraepithelial neoplastic lesions by fluorescence bronchoscopy. Chest 113:696-702. (1998).

    51. 1997

  51. Award N, MacAulay C, Lam S. Detection & Treatment of Early Lung Cancer Using d-Aminolevulinic acid. J of Bronchology 4:13-17. (1997).

  52. Lam S. Comprehensive management of lung cancer (Editorial). J of Bronchology 4:199-200. (1997).

  53. Payne P, Sebo TJ, Doudkin A, Garner D, MacAulay C, Lam S, LeRiche JC, Palcic B. : Sputum screening by quantitative microscopy. A re-examination of a portion of the National Cancer Institute Cooperative Early Lung Cancer Study. Mayo Clin Proc 72:697-704. (1997).

  54. Thieberville L, Payne P, Metayer J, Vielkinds J, LeRiche J, Palcic B, Lam S. Molecular follow-up of a pre-invasive bronchial lesion treated by a 13-cis-retinoic acid. Human Pathology 28: 108-10. (1997).

  55. Wistuba II, Lam, S, Behrens C, Virmani AK, LeRiche JC, Samet J, Srivastava S, Minna JD, Gazdar AF. Molecular damage in the bronchial epithelium of current and former smokers. JNCI 89: 1366-73. (1997).

  56. Yashima K, Piatyszek MA, Litzky LA, Kaizer L, Rogers T, Lam S, Srivastava S, Shay JW, Gazdar AF. Telomerase expression in bronchial epithelium during the multistage pathogenesis of lung carcinomas. Cancer Res. 57:2373-2377. (1997).

    57. 1996

  57. Lam S, Becker H. Future Diagnostic Procedures. Chest Surgery Clinics of North America. 6:363-380. (1996).

    58. 1995

  58. Frew AJ, Chan H, Lam S, Chan-Yeung M. Bronchial Inflammation In Occupational Asthma Due to Western Red Cedar Asthma. Am J Resp Crit Care Med 151:340-444. (1995).

  59. Harries M, Lam S, MacAulay C, Qu J, Palcic B. Diagnostic imaging of the larynx: autofluorescence of laryngeal tumors using the helium-cadmium laser. J of Laryngology & Otology 109:108-10. (1995).

  60. Ikeda N, MacAulay C, Lam S, Garner D, Payne P, Kato H, Konaka C, & Palcic B. Use of high resolution cytometry in predicting the biologic behavior of T1 adenocarcinoma of the lung. Analyt Quant Cytol Histol. 17(1):69-74 (1995).

  61. Kwan S, Lam S. Tracheopathia Osteoplastica. J of Bronchology 2:312-314. (1995).

  62. MacAulay C, Lam S, Payne PW, LeRiche JC, & Palcic B. Malignancy-associated changes in bronchial epithelial cells in biopsy specimens. Analyt Quant Cytol Histol. 17(1):55-61 (1995).

  63. Qu J, MacAulay C, Lam S, & Palcic B. Laser induced fluorescence spectroscopy at endoscopy: Tissue optics; monto carlo modeling and in-vivo measurements. Optical Engineering, 34;3334-43. (1995).

  64. Thiberville L, Bourguignon J, Metayer J, Bost F, Diarra-mehrpour M, Bignon J, Lam S, Martin JP & Nouvet G. Frequency and prognostic evaluation of 3p21-22 allelic losses in non-small cell lung cancer. Int J Cancer 64:371-377. (1995).

  65. Thiberville L, Payne P, Vielkinds J, Leriche J, Horsman D, Nouvet G, Palcic B, Lam S,. Evidence of Cumulative Gene Losses with Progression of Premalignant Epithelial Lesions to Carcinoma of the Bronchus. Cancer Research 55:5133-5139. (1995).

    66. 1994

  66. Chan-Yeung M, Lam S, Kennedy S, Frew AJ. Persistent asthma after repeated exposure to high concentrations of pulpmill gases. Am J Respir Crit Care Med 149:1676-80. (1994).

  67. Lam S. Photodynamic Therapy of Lung Cancer. Seminars in Oncology 6: 15-19. (1994).

  68. Lam S, MacAulay C, LeRiche JC, Ikeda N, Palcic B. Early localization of bronchogenic carcinoma. Journal of Diagnostic and Therapeutic Endoscopy 1:75-78. (1994).

  69. Qu J, MacAulay C, Lam S, & Palcic B. Optical properties of normal and carcinoma bronchial tissue. Applied Optics 33(31): 7397-7405 (1994).

  70. Sutedja G, Lam S, LeRiche JC, Postmus PE. Response and pattern of failure after photodynamic therapy for early stage lung cancer. Journal of Bronchology 1:295-298. (1994).

  71. Wong E, Lam S, Grafton C, Wong F, Morris J, McKenzie M, Goddard K, Yuen K. HDR Brachytherapy For Obstructive Bronchial Tumors. Journal of Bronchology 1:99-104. (1994).

    72. 1993

  72. Chan-Yeung M, McMurren T, Catonia-Begley F, Lam S. Occupational asthma in a technologist exposed to glutaraldehyde. J Allergy Clin Immunol 91:974-78. (1993).

  73. Frew AJ, Chan H, Dryden P, Salari H, Lam S, Chan-Yeung M. Immunologic studies of the mechanisms of occupational asthma caused by western red cedar. J Allergy Clin Immunol 92:466-78. (1993).

  74. Lam S. Photodynamic Therapy of Lung Cancer. Thorax 48(5):469. (1993).

  75. Lam S, MacAulay C, Hung J, LeRiche JC, Profio AE, Palcic B. Detection of dysplasia and carcinoma in-situ using a Lung Imaging Fluorescence Endoscope (LIFE) Device. J Thorac Cardiovasc Surg. 105:1035-40. (1993).

  76. Lam S, MacAulay C, Palcic B. Detection and localization of early lung cancer by imaging techniques. Chest 103:12-14. (1993).

  77. Mitsudomi T, Lam S, Shirakusa T, Gazdar A. Detection and sequencing of p53 gene mutations in bronchial biopsy samples in patients with lung cancer. Chest 104:362-365. (1993).

    78. 1992

  78. Kluftinger AM, Davis ML, Quenville NF, Lam S, Hung J, Palcic B. Detection of squamous cell cancer and pre-cancerous lesions by imaging of tissue autofluorescence in the hamster cheek pouch model. Surgical Oncology 1:183-188. (1992).

  79. Lam S, Hung J, Kennedy SM, LeRiche J, Vedal S, Nelems B, MacAulay CE, Palcic B. Detection of dysplasia and carcinoma in situ by ratio fluorometry. Am Rev Respir Dis 146:1458-1461. (1992).

  80. Steven FS, Lam S, MacAulay C, Palcic B. Fluorescent localization of abnormal cells in smokers obtained from lungs of patients with lung cancer. Anticancer Research 12:625-630. (1992).

    81. 1991

  81. Chan-Yeung M, Lam S, Chan H, Tse K. S. , Salari H. The release of platelet activating factor into plasma during allergen-induced bronchoconstriction. J. Allergy Clin. Immunol. 87: 667-73. (1991).

  82. Hung J, Lam S, LeRiche JC, Palcic B. Autofluorescence of Normal and Malignant Bronchial Tissue. Lasers in Surgery and Medicine 11: 99-105. (1991).

  83. Lam S, Al-Majed S, Chan H, Tse K, LeRiche JC, Chan-Yeung M. Differences in mediator release between allergic rhinitis and asthma. J. Allergy Clin. Immunol. 87: 842-849. (1991).

  84. Lam S, Hung J, Palcic B. Mechanism of detection of early lung cancer by ratio fluorometry. Lasers in Life Sciences 4(2): 67-73. (1991).

  85. Palcic B, Lam S, Hung J, MacAulay C. Detection and localization of early lung cancer by imaging techniques. Respiratory Disease 10:4-5. (1991).

  86. Palcic B, Lam S, Hung J, MacAulay C. Detection and localization of early lung cancer by imaging techniques. Chest 99: 742-743. (1991).

    87. 1990

  87. Chan-Yeung, Lam S. Evidence for mucosal inflammation in occupational asthma. Clin and Exper Allergy, 20:1-5. (1990).

  88. Korbelik M, Hung J, Lam S, Palcic B. "The effects of low density lipoproteins on the uptake of Photofrin II". Photochem Photobiol, 51:191-196. (1990).

  89. Lam S, Jung J, MacAulay C, Jaggi B, Palcic B. Fluorescence imaging of early lung cancer. IEEE Eng Med Biol 1291:1142-1143. (1990).

  90. Lam S, Palcic B, McLean D, Hung J, Korbelik M, Profio AE. Detection of early lung cancer using low dose Photofrin II. Chest, 97:333-337. (1990).

  91. Quyumi AK, Jamieson WR, Godin DV, Lam S, Ko KM, Germann E, Van den Broek J. Response to Allupurinol pre-treatment in a swine model of heart lung transplantation. J. Invest Surg 3:331-40. (1990).

    92. 1989

  92. Chan-Yeung M, Chan H, Tse KS, Salari H, Lam S. Histamine and leukotrienes release in bronchoalveolar fluid during plicatic acid-induced bronchoconstriction. J Allergy Clin Immunol, 84:762-68. (1989).

  93. Profio AE, Khoury TF & Lam S. "Measurement of Concentration of DHE in tissue, J. Laser Applications, 1(2):21-23. (1989).

    94. 1988

  94. Chan-Yeung M, Kinsella M, Tse K, Salari H, Lam S. Mediator release after nasal airway challenge. Am J Rinol, 2:183-188. (1988).

  95. Chan-Yeung, LeRiche J, MacLean L, Lam S. Comparison of cellular and protein changes in bronchial lavage fluid of symptomatic and asymptomatic patients with red cedar asthma on follow-up examination. Clin Allergy 18:359-365. (1988).

  96. Lam S, Salari H, Chan H, Chan-Yeung M. Release of leukotrienes in patients with bronchial asthma. J Allergy Clin Immunol 81:711-717. (1988).

  97. Ochnio JJ, Abboud RT, Lam S, Johal SS, Smith CE, Johnson DA. Bronchial leukocyte proteinase inhibitor levels in bronchial washings in asthma. Chest 93:1008-1012. (1988).

  98. Zwirewich CV, Muller NL, Lam S. CT and bronchoscopy in the evaluation of complete bronchial obstruction prior to photodynamic therapy. Am J Radiol 151:897-901 (1988).

    99. 1987

  99. Lam S, Chan-Yeung M, LeRiche JC, Phillips D. Cellular and protein changes in bronchial lavage fluid following late asthmatic reaction in patients with red cedar asthma. J Allergy Clin Immunol 80:44-50. (1987).

  100. Lam S, Kostashuk E, Miller R, LeRiche JC, Laukkanen E. Laser therapy for obstructive endobronchial tumors. Laser in Surgery and Medicine 7:29-35. (1987).

  101. Lam S, Kostashuk EC, Coy P, Laukkanen E, LeRiche JC, Mueller HA, Nelems B. A randomized comparative study of the safety and efficacy of photodynamic therapy using Photofrin II combined with palliative radiotherapy versus radiotherapy alone in patients with inoperable obstructive non-small cell bronchogenic carcinoma. Photobiol Photochem 46:893-897. (1987).

    102. 1986

  102. Chan-Yeung M, Lam S. State of the art: Occupational Asthma. Am Rev Respir Dis 133:686-703. (1986).

  103. Lam S, Kostashuk E, Miller R, LeRiche JC, Lee-Chuy E. Predicting the response of obstructive endobronchial tumors to photodynamic therapy. Cancer 58:2298-2306. (1986).

    104. 1985

  104. Chan-Yeung M, Enarson D, Lam S. Pulmonary function measurements in industrial setting. Chest 88:270-275. (1985).

  105. Chan-Yeung M, Vedal S, Lam S, Enarson D. Immediate skin reactivity and its relationship to age, sex, smoking and occupational exposure. Arch Environ Health 40:53-57. (1985).

  106. Enarson DA, Chan-Yeung M, Tabona M, Kus J, Vedal S, Lam S. Predictors of bronchial hyperexcitability in grainhandlers. Chest 87:452-455. (1985).

  107. Lam S, LeRiche J, Kijek K. Effect of filtration and concentration on the composition of bronchoalveolar lavage fluid. Chest 87:740-742. (1985).

  108. Lam S, LeRiche JC, Kijek K, Phillips D. Bronchial lavage: effect of lavage volume on cellular and protein recovery. Chest 88:856-859. (1985).

  109. Vedal S, Chan-Yeung M, Ashley MJ, Enarson D, Lam S. Do family history or personal history of allergy predict immediate skin test reactivity. Can Med Assoc J 132:34-37. (1985).

    110. 1984

  110. Kwan P, Lam S, Klimo P. Light chain disease and pleural effusion. Chest 86:494-496. (1984).

  111. Miller RR, Churg AM, Hutcheon M, Lam S. Pulmonary alveolar proteinosis and aluminum exposure. Am Rev Respir Dis 130:312-314. (1984).

    112. 1983

  112. Kwan P, Lam S, Chow AW, Lepawsky M, Glanzberg M. Empyema due to clostridium perfringens. Can Med Assoc J 128:1420-1422. (1983).

  113. Lam S, Tan F, Chan H, Chan-Yeung M. Relationship between types of asthmatic reactions, non-specific bronchial reactivity and specific IgE antibodies in patients with red cedar asthma. J Allergy Clin Immunol 72:134-139. (1983).

    114. 1982

  114. Chan-Yeung M, Lam S. Clinical features and the natural history of patients with asthma due to Western Red Cedar. Am J Med 72:411-415. (1982).

  115. Lam S, Smith JA, Burton JD, Evelyn RG et al. Legionella longbeachae pneumonia: diagnosis by bronchial brushing. Can Med Assoc J 127:223-224. (1982).

    116. 1981

  116. Chan-Yeung M, Schulzer M, MacLean L, Dorken L, Tan F, Lam S, Grzybowski S. A follow-up study of the grain elevator workers in the port of Vancouver. Arch Environ Health 36:75-80. (1981).

  117. Lam S, Abboud R, Chan-Yeung M, Tan F. Use of maximal expiratory flow-volume curves with air and helium-oxygen in the detection of ventilatory abnormalities in population surveys. Am Rev Respir Dis 123-214-237. (1981).

    118. 1980

  118. Lam S, Chan-Yeung M. Ethylenediamine - induced asthma. Am Rev Respir Dis 121:151-155. (1980).

  119. Lam S, Chan-Yeung M, Abboud R, Kreutzer D. Interrelationships between serum chemotactic factor inactivator alpha-1-antitrypsin deficiency and chronic obstructive lung disease. Am Rev Respir Dis 121:507-512. (1980).

    120. 1979

  120. Lam S, Abboud R, Chan-Yeung M, Rushton M. . Neutrophil elastase and pulmonary function in subjects with intermediate alpha-1-antitrypsin deficiency. Am Rev Respir Dis; 119:941-951. (1979).

  121. Lam S, Wong R, and Chan-Yeung M. . Nonspecific bronchial reactivity in occupational asthma. J Allergy Clin Immunol; 63(1):28-34. (1979).

Non Peer-Reviewed Papers
Peer-Reviewed Papers | Non Peer-Reviewed Papers | Books (and Chapters) | Presentations and Symposium Proceedings | Abstracts | Patents | Other Forms of Publications

    2004

  1. Buys T, Garnis C, Coe B, MacAulay C, Lam S, Lam W . Genetic alterations on chomosome 5p in bronchial squamous carcinoma in situ. 95th Annual AACR Conf. Proceedings. In press. (2004).

  2. Cleveland KC, LeRiche J, MacAulay C, Lam S, Lam W . Characterization of genetic alterations in lung cancer progression. United States and Canadian Academy of Pathology Annual Meeting Proceedings. In press (2004).

  3. Cleveland KC, LeRiche J, MacAulay C, Lam S, Lam WL . Characterization of Genetic Alterations in Early Stage Lung Cancer. Canadian Federation of Biological Societies (CFBS) 47th Annual Meeting: Proceedings pg. 57 (2004).

  4. Coe BP, Lee E, Gazdar AF, Minna J, Lam S, MacAulay C, Lam W. Sub-megabase resolution array CGH profiling of small cell lung cancer cell lines. 95th Annual AACR Conf. Proceedings, in press (2004).

  5. Coe BP, Lee E, Lam S, MacAulay C, Lam W . Identification of Highly Frequent Microalterations in Small Cell Lung Cancer by SMRT Array CGH. Canadian Federation of Biological Societies (CFBS) 47th Annual Meeting: Proceedings pg. 58 (2004).

  6. Garnis C, Coe B, Henderson LJ, Ishkanian A, Watson S, Marra M, Minna J, Lam S, MacAulay C, Lam W. . Construction and Optimization of Chromosome Arm-Specific Comparative Genomic Hybridization Arrays for Identifying Genetic Alterations in Preinvasive Lung Cancers. Chest 2004;125: 104S-105S. Thomas L Petty Aspen Lung Conference 46th Annual Meeting, Aspen, Colorado, June 4-7, (2004).

  7. Garnis C, Davies J, MacAulay C, Lam S, Lam W. Genome wide search for novel genetic alterations in bronchial squamous cell carcinoma. 95th Annual AACR Conf. Proceedings, (2004).

  8. Garnis C, Davies J, Vucic E, MacAulay C, Lam S, Lam W . Novel genetic alterations in early stage lung cancer. 54th American Society of Human Genetics Annual Meeting Proceedings, pp. 366. (2004).

  9. Garnis C, Davies J, Vucic J, Coe B, Ge Y, Gazdar A, Ramirez R, Shay J, Minna J, MacAulay C, Lam S, Lam W. Whole genome sub-megabase resolution tiling (SMRT) array comparative genomic hybridization (CGH) analysis of lung cancer and immortalized cell lines. 2004Winter Lung Cancer SPORE Meeting Proceedings (2004).

  10. Hung JY, Rebello J, Lam S, leRiche JC. . Selection of pre-invasive lung cancer binding peptides using random phage display libraries. Eur J Cancer;2(8):87. (2004).

  11. Kaan PM, Cutz JC, MacAulay C, Lam S, Lam WL. Expression of WNT proteins in lung cancer. United States and Canadian Academy of Pathology Annual Meeting Proceedings. (2004).

  12. Lee E HL, Coe BP, Lam S, MacAulay C, Lam W . High resolution array CGH profiling of small cell lung cancer cell lines. 54th American Society of Human Genetics Annual Meeting Proceedings, pp 487. (2004).

  13. Lonergan K, MacAulay C, Ng R, Chan T, Chari R, Lam S, Lam WL. Comparing gene expression profiles during development of squamous cell lung carcinoma. 95th Annual AACR Conf. Proceedings, (2004).

  14. MacAulay C, Lonergan K, Chi B, Zuyderduyn S, Shein J, Tsao M, leRiche J, Jones S, Marra M, Lam S, Lam W. . Serial Analysis of Gene Expression Profiles of Developmental Stages in Non-Small Cell Lung Carcinoma. CHEST 2004 (Supp) 125:97S. Thomas L Petty Aspen Lung Conference 46th annual Meeting, Aspen, Colorado, June 4-7, (2004).

  15. McWilliams A, Mayo JR, Ahn MI, MacDonald S, Lam S. . The behavior of pulmonary nodules found on lung cancer screening. Eur Respir J;24(Supp 48):P3068, 490s. (2004).

  16. Tichelaar JW, Zhang Y, LeRiche JC, Lam S, Anderson MW. . Activation of the AKT/HF-KB signalling axis in developing lung neoplasia. CHEST 2004 (Supp) 125:153S. Thomas L Petty Aspen Lung Cancer Conference 46th Annual Meeting, Aspen, Colorado, June 4-7, (2004).

  17. Vucic E, Garnis C, Davies J, MacAulay C, Lam S, Lam W . Whole Genome Display of Lung Squamour Cell Lines. Canadian Federation of Biological Societies (CFBS) 47th Annual Meeting: Proceedings, pg. 67. (2004).

    18. 2003

  18. Buys T, Garnis C, Coe B, MacAulay C, Lam S, Lam W. . Genetic Alterations on Chromosome 5p in Bronchial Squamous Carcinoma in Situ. BCCA Annual Cancer Conference, Vancouver, BC, November 27-29. Abstract #59, Abstract Book pg. 17 (2003).

  19. Cleveland KC, leRiche JC, MacAulay C, Lam S, Lam W. . Characterization of genetic alterations in lung cancer progression. BCCA Annual Cancer Conference, Vancouver, BC, November 27-29. Abstract #105, Abstract Book pg. 29 (2003).

  20. Coe B, Garnis C, Ishkanian A, Lam S, MacAulay C, Lam W. . Tiling Resolution Array CGH Profiling of Chromosome Arms 3p and 5p in Lung Cancer Cell Lines. BCCA Annual Cancer Conference, Vancouver, BC, November 27-29, Abstract #102, Abstract Book pg. 29 (2003).

  21. Coe BP, Garnis C, Ishkanian A, Minna J, Lam S, Tsao M, MacAulay C, Lam W. . Sub-megabase resolution array CGH profiling of chromosome arms 3P and 5P in lung cancer. International Conference on Applied Genomics. 9th ESACP/16th ESDQP Meeting, Oct. 1-4. Abstract Book pg. 86 (2003).

  22. Garnis C, MacAulay C, Lam S, Lam W. . Genome wide search for novel genetic alterations in pre-invasive bronchial squamous. International Conference on Applied Genomics, Abstract Book, Proceedings. pg. 38 (2003).

  23. Guan J, Cutz JC, Bayani J, Wang Y, Xue H, Wu R, Sutcliffe M, leRiche JC, English J, Bebb G, Gout PW, Squire J, Lam S, Wang YZ. . Establishment of a novel human lung cancer tissue xenograft model. BCCA Annual Cancer Conference, Vancouver, BC, November 27-29. Abstract #106, Abstract Book pg. 29. (2003).

  24. Guan J, Wang Y, Xue H, Doxsee D, Sutcliffe M, Cutz JC, leRiche JC, Bebb G, Gout PW, Lam S, Wang YZ. . Potential use for sulfasalazine in lung cancer therapy. BCCA Annual Cancer Conference, Vancouver, BC, November 27-29. Abstract #104, Abstract Book pg. 29 (2003).

  25. Guillaud M, Lam N, Lam S, MacAulay C. . Cellular sociology for the analysis of MIBI immunohistochemical staining of bronchial biopsies. International Conference on Applied Genomics. (9th ESACP/16th ESDQP Meeting, Oct. 1-4. Abstract Book pg. 71 (2003).

  26. Henderson LJ, Coe B, Minna J, Lam S, MacAulay C, Lam W. . High resolution array CGH detects two regions of amplificatin on chromosome arm 1p in small cell lung cancer cell lines. BCCA Annual Cancer Conference, Vancouver, BC, November 27-29. Abstract #101, Abstract Book pg. 29 (2003).

  27. Henderson LJ, Coe CP, Minna JD, Lam S, MacAulay C, Lam W: . High resolution array CGH detects recurrent regions of amplification on chromosome arm 1P in small cell lung cancer. International Conference on Applied Genomics. Proceedings, pg 85 (2003).

  28. Huang Z, McWilliams A, Lui H, McLean DI, Lam S, Zeng H.. Near-infrared raman spectroscopy for lung cancer diagnosis. BCCA Annual Cancer Conference, Vancouver BC, November 28-29, Abstract 98, Abstract Book pg. 28 (2003).

  29. Jones S, Ruzanov P, MacAulay C, Lam W, Lonergan K, Lam S, Zuyderduyn S, Schein J, Oveisi M, Varhol R, Rusaw S, Schnerch A, Khattra J, Thomson J, Humphries K, Eaves C, Ling V, Marra M. . High-throughput serial analysis of gene expression profiling of cancers. Advances in Genome Biology and Technology, Marco Island, Florida, February 5-8, (2003).

  30. Lam W, Lonergan K, Zuyderduyn S, Shein J, Tsao M, leRiche J, Jones S, Marra M, MacAulay C, Lam S. . Gene expression profiles of developmental stages of non-small cell lung carcinoma. 4th International SAGE Meeting, Amsterdam, the Netherlands, January 17-19(Submitted). (2003).

  31. Mayo JR, McWilliams A, Muller N, Palcic B, Lam S. . Combination of computer assisted low dose spiral CT scan for lung cancer screening. Radiology;225(p):233. (2003).

  32. Zeng H, Petek M, Terceij Zorman M, McWilliams A, Palcic B, Lam S. . Integrated endoscopy system for simultaneous imaging and spectroscopy for early lung cancer detection. BCCA Annual Cancer Conference, Vancouver, BC November 28-29, Abstract 99, Abstract Book pg. 28 (2003).

    33. 2002

  33. Cox G, Miller JD, Noth I, Leff AR, McWilliams A, Fitzgerald M, Lam S. . Early clinical experience with thermal bronchoplasty for the treatment of asthma. American Thoracic Society Meeting, May 17-22, Abstract 507917. (2002).

  34. McWilliams A, Mayo J, Muller N, Palcic B, Lam S. . Role of LIFE bronchoscopy in an early lung cancer detection program. 12th World Congress of Bronchology and Bronchoesophagology. Boston, MA. USA, June 18, (2002).

    35. 2001

  35. McWilliams A, Lam S. . Endobronchial Electrocautery: Review of a series of 41 subjects. ACCP Annual Meeting, Philadelphia, USA, November 7, Abstract 159. (2001).

  36. McWilliams A, Mayo J, Muller N, Palcic B, English J, Lam S. . Combination of computer assisted sputum analysis and low dose spiral CT for lung cancer screening. ACCP Annual Meeting, Philadelphia, USA, November 6. Abstract 93. (2001).

    37. 1999

  37. Zeng H, MacAulay C, Lam S, Palcic B. . Light induced fluorescence endoscopy (LIFE) imaging system for early cancer detection. SPIE; 3863:275-282. (1999).

    38. 1998

  38. MacAulay C, Lam S, Klein-Parker H, Gazdar A, Guillaud M, Payne P, LeRiche J, Dawe C. Band P, Palcic B. . Intermediate endpoint biomarkers for lung cancer chemoprevention. SPIE; 3260-28:207-211. (1998).

    39. 1995

  39. MacAulay C, Lam S, Qu J, Man C, Harries M and Palcic B: . Optical properties of normal and malignant tissues in the nasopharynx and the larynx. SPIE Proc.; 2395:153-157. (1995).

  40. Qu J, MacAulay C, Lam S, and Palcic B: . Mechanisms of ratio fluorescence imaging of diseased tissue. In: Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II, Alfano RR, Ed. SPIE 2387:71-79, (1995).

    41. 1994

  41. Lam S, MacAulay C, LeRiche J, Ikeda N and Palcic B: . Fluorescence imaging of early lung cancer. SPIE 2324:2-8, (1994).

  42. Qu J, MacAulay C, Lam S and Palcic B: . Laser-induced fluorescence spectroscopy at endoscopy. Proc SPIE Biomedical Optics; 2133: 162-169. (1994).

  43. Qu J, MacAulay C, Lam S, Zeng H and Palcic B: . Fluorescence in normal and carcinoma bronchial tissue. Proc SPIE Biomedical Optics; 2134A:236-246. (1994).

    44. 1993

  44. Lam S, MacAulay C, LeRiche JC, Qu J, Krosl G, Zeng H, Korbelik M, Palcic B. . Fluorescence imaging of pre-malignant and malignant tissues. Proc SPIE; 1881:160-167. (1993).

    45. 1991

  45. Korbelik M, Krosl G, Lam S, Chaplin DJ, Palcic B. . Microlocalization of Photofrin in neoplastic lesions. Proc SPIE,; 1426: 172-179. (1991).

  46. Lam S, Grafton C, Coy P, Voss N. . A randomized comparative study of the safety and efficacy of photodynamic therapy using photofrin combined with palliative radiotherapy versus palliative radiotherapy alone in patients with inoperable obstructive non-small cell bronchogenic carcinoma. Proc SPIE;1616:20-28. (1991).

  47. Palcic B, Lam S, MacAulay C, Hung J, Jaggi B, Radjinia M, Pon A, Profio AE. . Lung Imaging fluorescence endoscope: development and experimental prototype Proc SPIE; 1448: 113-117. (1991).

  48. Profio AE, Balchum OJ, Lam S. . Endoscopic fluorescence detection of early lung cancer Proc SPIE; 1426: 44-46. (1991).

    49. 1990

  49. Lam S, Hung J, Palcic B. . Detection of lung cancer by ratio fluorometry with and without Photofrin II. Proc SPIE;1201:561-568. (1990).

Books (and Chapters)
Peer-Reviewed Papers | Non Peer-Reviewed Papers | Books (and Chapters) | Presentations and Symposium Proceedings | Abstracts | Patents | Other Forms of Publications

    In Press

  1. Collins JM, Eckelman WC, Evelhoch JL, Feld MS, Harms SE, Jain RK, Lam S, Mulshine JL, Wahl RL, Weinstein JN. Conference of the Joint Working Group on Quantitative In Vivo Functional Imaging in Oncology. January 6-8, 1999, Washington, DC, Eds Shtern F, Winfield D, Acad Radiol (In Press).

  2. Lam S, McWilliams A. The Role of Autofluorescence Bronchoscopy in Diagnosis of Early Lung Cancer. In: IASLC Textbook of Prevention and Early Detection of Lung Cancer. Eds. FR Hirsch, PA Bunn Jr, H Kato, JL Mulshine. (In Press).

  3. Lam S.. Detection of Preneoplastic Lesions. Lung Cancer. 3rd Edition. (In Press).

    4. 2005

  4. Lam S, McWilliams A. . The Role of Autofluorescence Bronchoscopy in Diagnosis of Early Lung Cancer. In: IASLC Textbook of Prevention and Early Detection of Lung Cancer. Eds. FR Hirsch, PA Bunn Jr. H Kato, JL Mulshine, (2005).

  5. Miller Y, Petty TL, Lam S. . The Early Detection of Lung Cancer using Bronchoscopy and Cytologic Analysis. In: Lung Cancer, Principles and Practice (3rd ed). Eds. H Pass, D Carbone, D Johnson, J Minna, A Turrisi. Philadelphia: Lippincott Williams and Wilkins, pp. 189-199. (2005).

    6. 2004

  6. Lam S, McWilliams A. Photodynamic therapy - Early lung cancer. In: Interventional Pulmonary Medicine. Eds. JF Beamis, P Mathur, A Mehta, C Lenfant. New York: Marcel Dekker; p. 271-285 (2004).

    7. 2003

  7. Lam S, MacAulay C, leRiche J, Gazdar AF. Key Issues in Lung Chemoprevention Trial of New Agents IN: Recent Results in Cancer Research vol. 163: Tumor Prevention and Genetics. Senn H-J, Morant R, Eds. Berlin: Springer Verlag. pp 182-195 (2003).

  8. McWilliams A, Lam S. The Utilization of Autofluorescence in Flexible Bronchoscopy Flexible Bronchoscopy, 2nd ed. Eds. KP Wang, A. Mehta, JF Turner. Boston: Blackwell Science pp 138-145 (2003).

  9. Wagnieres G, McWilliams A, Lam S. . Lung cancer imaging with fluorescence endoscopy IN: Handbook of Biomedical Fluorescence. Eds. M Mycek, B. Pogue. New York: Marcel Dekker. pp 361-396 (2003).

    10. 2000

  10. Gazdar AF, Lam S, Wistuba II. Molecular and cytologic techniques of early detection. IN: Lung Cancer, Principles and Practice (2nd ed.). Eds. H. Pass, J. Mitchell, D. Johnson, A. Turrisi, J. Minna. Philadelphia: Lippincott Williams & Wilkins pp 407-424. (2000).

  11. Lam S, Becker H. Fluorescence and Ultrasound Bronchoscopy. Pulmonary & Critical Care (PCCU) Online, ACCP  http://www.chestnet.org/education/pccu/vol15/lesson07-08.index.html (2000).

  12. Lam S, Gazdar AF. Chemoprevention Treatment of Bronchial Intraepithelial Neoplasia. American Association of Cancer Research, FDA Committee on Chemoprevention (2000).

  13. Lam S, Gazdar AF. Chemoprevention Treatment of Bronchial Intraepithelial Neoplasia American Association of Cancer Research, FDA Committee on Chemoprevention (2000).

  14. Pass H, Cortese D, Edell E, Lam S, Kato H. The use of light for the early detection and treatment of lung cancer IN: Lung Cancer, Principles and Practice (2nd ed.). Eds. H. Pass, J. Mitchell, D. Johnson, A. Turrisi, J. Minna. Philadelphia: Lippincott Williams Wilkins. pp 425-437 (2000).

    15. 1999

  15. Andrews Russell, Bigio IJ, Bohorfoush III AG, Brezinski M, Fujimoto JG, Lam S, Mulshine JL, Richards-Kortum R, Svanberg K, Tadir Y, Tromberg BJ. Report of the Advisory Council on Optical Technologies, October 24-25, 1997. Eds Bigio IJ, Shtern F, Ascher SM. Acad Radiol 6(supp):S153-S192. (1999).

  16. Collins JM, Eckelman WC, Evelhoch JL, Feld MS, Harms SE, Jain RK, Lam S, Mulshine JL, Wahl RL, Weinstein JN. . Conference of the Joint Working Group on Quantitative In Vivo Functional Imaging in Oncology. January 6-8, Washington, DC, Eds Shtern F, Winfield D, Acad Radiol (in press). (1999).

  17. Lam S. Fluorescence Bronchoscopy. In: Harrison's Online. Eds Braunwald E, Fauci AS, Isselbacher KJ, Kasper DL, Hauser SL, Longo DL, Jameson JL. Boston: McGraw Hill (1999).

  18. Lam S. Fluorescence Imaging for Early Lung Cancer In: Interventional Pulmonology Eds. J. Beamis Jr JF, Mathur PN. Boston: McGraw Hill (1999).

  19. Lam S, MacAulay C. Endoscopic detection of preneoplastic lesions. In: Lung Tumors: Fundamental Biology and Clinical Management. Eds Brambilla C and Brambilla E. New York: Marcel Dekker Inc (1999).

  20. Lam S, MacAulay C. Optical Imaging - Translational research opportunities in lung cancer. In: Autofluorescence Bronchoscopy. Principles and Clinical Applications. Ed T Fujisawa, Kanehara & Co. Ltd, Tokyo, Japan (1999).

    21. 1998

  21. Lam S, MacAulay C. Endoscopic Localization of preneoplastic lung lesoins. In: Clinical and Biological Basis of Lung Cancer Prevention. Eds. Y Martinet, FR Hirsch, N Martinet, JM Vinguard, JL Mulshine. Basel/Switzerland: Birkhauser Verlag (1998).

  22. Lam S, Palcic B. . Fluorescence Detection. In: Advances in the Diagnosis and Therapy of Lung Cancer. Ed. JA Roth, JD Cox, WK Hong. Blackwell Scientific Publications Inc. Cambridge, MA. Second Edition. Pg. 269 - 386. (1998).

  23. Palcic B, Payne P, MacAulay C, Lam S. Malignancy associated changes (MAC) inlung cancer. In: Laboratory Testing of Solid Tumors. Eds W Albert, J Baak, D Moss. Blackwell Scientific Publishers (1998).

    24. 1997

  24. Lam S, Palcic B. Fluorescence Detection. In: Lung Cancer (2nd Edition). Eds. JA Roth, JD Cox, WK Hong. Cambridge: Blackwell Scientific Publications Inc (1997).

    25. 1996

  25. Lam S. Bronchoscopic Photodynamic & Laser Diagnosis and Therapy of Lung Neoplasms In: Current Opinion in Pulmonary Medicine, Ed. Glen A. Lillington, July (1996).

  26. Lam S. Detection & Treatment of Pre-invasive Lung Cancer. Balkan Congress of Oncology. Ed. George Antypas. Monduzzi Editore, Bologna (Italy) (1996).

    27. 1995

  27. Lam S, Profio AE. Diagnosis of Early Lung Cancer by Fluorescence Bronchoscopy. In: Minimally Invasive Techniques in Thoracic Medicine and Surgery. Ed. M. Hetzel, Chapman & Hall Ltd. Scientific, Technical & Medical Publishers (1995).

    28. 1993

  28. Lam S, Palcic B. Fluorescence Detection. In: Advances in the Diagnosis and Therapy of Lung Cancer. Eds. JA Roth, JD Cox, WK Hong. Blackwell Scientific Publications Inc, Cambridge, MA (1993).

    29. 1991

  29. Lam S. Hung J, Palcic B. Detection and localization of early lung cancer by laser-induced fluorescence. In: Trends in Photochemistry and Photobiology 2:309-322. (1991).

    30. 1990

  30. Lam S. . Use of Photofrin in localization and treatment of lung cancer. In: Photodynamic Therapy in Oncology - Clinical Applications for the 1990's. Ed. M.S. McPhee, B.C. Wilson. Lederle Laboratories, Cyanamid, Canada. (1990).

    31. 1987

  31. Lam S, Chan-Yeung M. Occupational asthma: natural history, evaluation and management. In Occupational Pulmonary Disease, Eds. J.J. Hanley, L. Rosenstock. 2:373-381. (1987).

    32. 1985

  32. Lam S, Kostashuk E, Olivotto I, LeRiche JC, Miller R. Combined photodynamic therapy and radiotherapy in the treatment of endobronchial tumors. In Photodynamic Therapy of tumors and Other Diseases. Eds. G. Jori, C. Perria. Libreria Progetto Publ., Padova (1985).

Presentations and Symposium Proceedings
Peer-Reviewed Papers | Non Peer-Reviewed Papers | Books (and Chapters) | Presentations and Symposium Proceedings | Abstracts | Patents | Other Forms of Publications

    2000

  1. Lam S. Lung cancer control strategy in the new millennium. Presidential Award Symposium, 9th World Conference on Lung Cancer, Tokyo, Japan, September 14 (2000).

  2. Lam S. Optical imaging technologies for detection of early lung cancer. Chinese Academy of Life Sciences, Beijing, China, April 21 (2000).

    3. 1999

  3. Lam S. Symposium on Early Detection and Screening for Lung Cancer. American Thoracic Society International Conference, San Diego, CA, USA, April 23-28 (1999).

  4. Lam S. Session Chair. Conference of the Joint Working Group on Quantitative In vivo Functional Imaging on Oncology, U.S. Public Health Service's Office on Women's Health and the National Cancer Institute, Arlington, Virginia, USA, January 6-8 (1999).

  5. Lam S. Detection and Localization of Early Lung Cancer by Fluorescence Bronchoscopy using the LIFE-Lung System. The IASLC - WAB Joint International Conference on Lung Cancer and Thoraco-Pulmonology, Genoa, Italy, November 26 (1999).

  6. Lam S. LIFE Bronchoscopy. The American Association for Thoracic Surgery postgraduate course in general thoracic surgery, New Orleans, LO, USA, April 18 (1999).

  7. Lam S. Detection and Localization of Early Lung Cancer by Fluorescence Bronchoscopy. First Chiba International Workshop on Lung Cancer - Early Detection, Chiba University, Chiba, Japan, February 12 (1999).

  8. Lam S. Early Diagnosis of Lung Cancer. China-Canada Early Cancer Detection Research Center opening ceremony, Tongji Medical University, Wuhan, China, October 25 (1999).

  9. Lam S. Early Detection of Lung Cancer in Population at Risk. Free University Hospital, Amsterdam, Netherlands, November 25 (1999).

    10. 1998

  10. Lam S. Early Bronchoscopic Diagnosis of Lung Cancer. 10th World Congress for Bronchology & Bronchesophagology, Budapest, Hungary, June 14-17 (1998).

  11. Lam S. Detection and localization of early lung cancer by fluorescence bronchoscopy. International Conference on Prevention and Early Diagnosis of Lung Cancer, Varese, Italy, December 10 (1998).

  12. Lam S. Early Detection of Lung Cancer. Tongji Medical University, Wuhan, China, September 4 (1998).

  13. Lam S. Recent Advances in Detection of Early Lung Cancer. Cancer Institute Hospital, Chinese Academy of Medical Sciences, Beijing, China, September 6 (1998).

  14. Lam S. Detection and localization of early lung cancer. 41st Annual Clinical Conference, New Frontiers in Research and Treatment of Aerodigestive Tract Cancers, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA, April 21 (1998).

  15. Lam S. Photodynamic therapy in early stage non-small cell lung cancer. Satellite Symposium on advances in the treatment of early lung cancer, Varese, Italy, December 8 (1998).

  16. Lam S. Photodetection of tumors. 7th Biennial Congress of the International Photodynamic Association, Nantes, France July 7-9 (1998).

  17. MacAulay C, Lam S, Klein-Parker H, Gazdar A, Guillaud M, Payne P, LeRiche J, Dawe C. Band P, Palcic B. Intermediate endpoint biomarkers for lung cancer chemoprevention. BIOS '98, San Jose, CA, USA, January 24-30, Abstract 3260B-28, Page 163, 1998. (1998).

    18. 1997

  18. Lam S. Photodynamic therapy of lung cancer. First Asia Pacific Inter-Science Congress of Medicine, Singapore, March 8 (1997).

  19. Lam S. Bronchoscopic detection of intraepithelial neoplasia. 63rd Annual International Scientific Assembly of the American College of Chest Physicians, New Orleans, LA, USA, October 28 (1997).

  20. Lam S. Chair-person. Session on Prevention/Epidemiology/Etiology, 8th World Conference on Lung Cancer, Dublin, Ireland, August 11 (1997).

  21. Lam S. Laser-assisted bronchoscopy in the early detection and treatment of lung cancer. 8th World Conference on Lung Cancer, Dublin Ireland, August 12 (1997).

  22. Lam S. Early detection of lung cancer. Plenary Lecture, First Asia Pacific Inter-Science Congress of Medicine, Singapore, March 7 (1997).

  23. Lam S. Recent Advances in Lung Cancer. Kyungpook National University Hospital, Taeku, Korea, June 14 (1997).

  24. Lam S. Fluorescence Bronchoscopy - Lecture and Live Demonstration. V International Meeting on Respiratory Endoscopy & the Killian Centenary, Sitges, Spain, May 8-10 (1997).

    25. 1996

  25. Lam S. Early Detection of Lung Cancer. Peter MacCallum Cancer Institute, Melbourne, Australia, March 13 (1996).

  26. Lam S. Detection & Treatment of Early Lung Cancer. Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, May 20 (1996).

  27. Lam S. Autofluorescence Bronchoscopy - The LIFE System. 19th Annual meeting of the Japan Society for Bronchology, May 23 (1996).

  28. Lam S. Detection & Treatment of Pre-invasive Lung Cancer. First Balkan Congress of Oncology, Athens, Greece, July 4 (1996).

  29. Lam S. Endoscopic Detection of Preneoplastic Lesions. IASLC Workshop on Prevention & Early Detection of Lung Cancer, Elsinore, Denmark, June 24 (1996).

  30. Lam S. Use of Fluorescence Bronchoscopy to Localize Preneoplastic Lesions for Chemoprevention Trials in Lung Cancer. International Cancer Chemoprevention Conference, Beijing, China, October 15 (1996).

  31. Lam S. Fluorescence Bronchoscopy for Preinvasive Lung Cancer. Transatlantic Interventional Pulmonary Course, Marseilles, France, October 17 (1996).

  32. Lam S. Fluorescence Bronchoscopy of Early Lung Cancer. 9th World Congress of Bronchology, Taipei, ROC, April 16 (1996).

  33. Lam S. Newer developments in bronchology. Postgraduate Course, European Respiratory Society Annual Meeting, Stockholm, Sweden, September 9 (1996).

  34. Lam S. Early Detection of Lung Cancer. Hong Kong Thoracic Society & Hong Kong University, Hong Kong, May 21 (1996).

    35. 1995

  35. Lam S. Detection & Treatment of Early Lung Cancer. Cancer Center, Jakarta, Indonesia (1995).

  36. Lam S. Detection & Treatment of Pre-invasive Lung Cancer. Medical Grand Rounds, MD Anderson Cancer Center, Houston, TX, USA (1995).

  37. Lam S. Symposium on Interventional Pulmonology - Imaging for Early Lung Cancer. American Thoracic Society Meeting, Seattle, WA, USA (1995).

  38. Lam S. Early Detection & Localization of Lung Cancer: A New Approach. Malaysian Medical Association Meeting, Penang, Malaysia (1995).

  39. Lam S. Challenge and impact of early detection in lung cancer. 7th International Symposium of the Society of Chinese Bioscientists in America, Toronto, ON, Canada, July 8 (1995).

  40. Lam S. Fluorescence Detection of Early Lung Cancer. Symposium on Recent Advances in The Treatment of Lung Cancer, UT South-western Medical Center, Dallas, TX, USA (1995).

  41. Lam S. The Bronchoscopic Fluorescence Laser System. 9th Annual Mount Elizabeth Hospital Seminar for Specialists, Singapore (1995).

  42. Lam S. Lung Cancer: Strategies for the 21st Century. Biology, Prevention and Management Fluorescence Detection, University of Toronto, Toronto, ON, Canada (1995).

  43. Lam S. LIFE System: A New Diagnostic Method in Early Lung Cancer. IV International Meeting In Respiratory Endoscopy, Sitges, Spain, May 6th (1995).

  44. Lam S. Screening for Lung Cancer. B.C. Thoracic Society Annual Symposium, Vancouver, BC, Canada. (1995).

  45. Lam S. Early Detection of Lung Cancer. 9th Annual Mount Elizabeth Hospital Seminar for Family Physicians, Singapore (1995).

  46. Lam S. Detection and Localization of Early Lung Cancer. ThoraxKlink, LVA-Baden, Heidelberg, Germany (1995).

  47. Lam S. Annual International Scientific Assembly. Lung Cancer Interactive Symposium, American College of Chest Physicians, 61st Annual International Scientific Assembly, New York, NY, USA (1995).

  48. Lam S. Endoscopy Workshops. IV International Meeting in Respiratory Endoscopy, Sitges, Spain, May 4-5 (1995).

  49. Lam S. Fluorescence Detection & Chemoprevention. BC Cancer Agency Lung Cancer Symposium, Vancouver, BC, Canada (1995).

  50. MacAulay C, Lam S, Qu J, Man C, Harries M & Palcic B. Optical properties of normal and malignant tissues in the nasopharynx and the larynx. SPIE Proceedings, San Jose, CA. February 3-9 (1995).

  51. Qu J, MacAulay C, Lam S, & Palcic B. Mechanisms of ratio fluorescence imaging of diseased tissue. In: Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II, Alfano RR, Ed. SPIE :71-79, 1995. (1995).

    52. 1994

  52. Lam S. Detection of early lung cancer and preneoplastic lesions. 7th World Conference on Lung Cancer, Colorado Springs, Colorado, USA, June 30 (1994).

  53. Lam S. Detection and Localization of Early Endobronchial Lesions. Long Beach Memorial Medical Centre, Long Beach, CA, USA, December 2 (1994).

  54. Lam S. Fluorescence imaging of early lung cancer. BiOS Europe '94, Lille, France, September 6-10 (1994).

  55. Lam S. Symposium on Recent Development in Bronchoscopy. 60th Annual International Scientific Assembly of the American College of Chest Physicians, New Orleans, LA, USA (1994).

  56. Lam S. Detection of Early Lung Cancer. Lahey Clinic, Burlington, MA, USA, November 15 (1994).

  57. Lam S. Fluorescence bronchoscopy in Lung Cancer. American Society for Laser Medicine and Surgery Fourteenth Annual Meeting. Toronto, Ontario, Canada, April 10, 1994 Lasers Surg Med 6:32 (1994).

  58. Lam S. Diagnosis and Treatment of Early Lung Cancer. Meet the Professor Seminar, World Conference on Lung Cancer, Colorado Springs, USA, June 27 (1994).

  59. Lam S. Fluorescence Spectroscopy & Imaging. Multidisciplinary Approaches," George R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA, November 14 (1994).

  60. Lam S. Detection of Early Lung Cancer and Pre-cancerous Lesions. Radium Hospital, Oslo, Norway, June 9 (1994).

  61. Lam S, MacAulay C, LeRiche J, Ikeda N & Palcic B. Fluorescence imaging of early lung cancer. SPIE :2-8, 1994. (1994).

  62. Qu J, MacAulay C, Lam S & Palcic B. Laser-induced fluorescence spectroscopy at endoscopy. Proc SPIE Biomedical Optics 2133: 162-169. (1994).

  63. Qu J, MacAulay C, Lam S, Zeng H & Palcic B. Fluorescence in normal and carcinoma bronchial tissue. Proc SPIE Biomedical Optics 2134A:236-246. (1994).

    64. 1993

  64. Lam S. Detection and Localization of Early Endobronchial Lesions. "Hands-on Laser Laboratory Workshop," UC Irvine Laser Bronchoscopy, Stents, Brachytherapy and Thoracoscopy Course for the Pulmonologist, Long Beach, CA, USA (1993).

  65. Lam S. Early Detection of Lung Cancer by Autofluorescence. Symposium on Controversies in the Management of Lung Cancer, American College of Chest Physicians Annual International Scientific Assembly Meeting, Orlando, FL, USA (1993).

  66. Lam S. Lung Cancer: Early Diagnosis. Postgraduate Course, American College of Chest Physicians, Annual International Scientific Assembly Meeting, Orlando, FL, USA (1993).

  67. Lam S. Flexible Fiberoptic Bronchoscopy in Early Diagnosis of Lung Cancer. First Annual Scientific Assembly of American Association for Bronchology, Orlando, FL, USA (1993).

  68. Lam S. Malignancy associated changes in bronchial epithelial cells. 4th IASLC Lung Tumor Biopsy Workshop, Airlie, Virginia, USA, April 13-16 (1993).

  69. Lam S. Fluorescence Bronchoscopy. Ecole Polytechnique Federale, Lausanne, Switzerland (1993).

  70. Lam S. Detection of Early Lung Cancer by Imaging Techniques. Lund University Medical Laser Center, Sweden (1993).

  71. Lam S. Detection and Treatment of Early Lung Cancer. Symposium on Modern Management of Thoracic Malignancies, The Royal College of Physicians and Surgeons of Canada Annual Meeting (1993).

  72. Lam S. Fluorescence Imaging of Pre-malignant and Malignant Tissues with and without Photosensitizers. Biomedical Optics Symposium, Los Angeles, CA, USA (1993).

  73. Lam S. Photodetection of Early Lung Cancer. UBC Department of Surgery Grand Rounds, Vancouver, BC (1993).

  74. Lam S. Fluorescence Imaging of Early Lung Cancer. III International Meeting in Respiratory Endoscopy, Sitges, Spain (1993).

  75. Lam S. Early Diagnosis of Lung Cancer by Fluorescence Bronchoscopy. International Meeting on New Frontiers in Lung Cancer, Genova, Italy (1993).

  76. Lam S. Fluorescence Imaging. Pittsburgh Cancer Institute Lung Cancer Conference, Pittsburg, PA, USA (1993).

  77. Lam S. Photodynamic Therapy of Lung Cancer. QLT Symposium on the Use of Photodynamic Therapy in Cancer, Vancouver, BC (1993).

  78. Lam S. Diagnosis and Management of Dysplasia and early Lung Cancer. Symposium Longchirurgie voor De Algemeen Chirung, Amsterdam, The Netherlands (1993).

  79. Lam S. Recent Advances in Bronchoscopy. Canadian Cardiopulmonary Technologists Meeting, Vancouver, BC (1993).

  80. Lam S. Diagnosis of Premalignant and Early Lung Cancer Lesions. NIH Workshop on the Primary and Secondary Prevention of Lung Cancer, USA (1993).

  81. Lam S. Recent Advances in Bronchoscopic Diagnosis and Treatment of Lung Cancer. Alberta Respiratory Technologist Association Annual Meeting, Edmonton, AB (1993).

  82. Lam S, MacAulay C, LeRiche JC, Qu J, Krosl G, Zeng H, Korbelik M, Palcic B. Fluorescence imaging of pre-malignant and malignant tissues. Proc SPIE 1881:160-167. (1993).

    83. 1992

  83. Lam S. Fluorescence Bronchoscopy. UCLA Symposium on Advances in the diagnosis and treatment of lung cancer, Santa Monica, CA, USA (1992).

  84. Lam S. Fluorescence Imaging of Early Lung Cancer. Symposium on Prevention, Early Detection and Treatment of Endobronchial Lung Cancer, European Cancer Center, Amsterdam, The Netherlands (1992).

  85. Lam S. Tumor Detection With and Without Photosensitizers. Gordon Research Conference on Lasers in Medicine and Biology. New London, NH, USA. (1992).

  86. Lam S. Photodynamic Therapy of Lung Cancer. Photodynamic Therapy Workshop, Western Institute of Laser, Santa Barbara, CA, USA (1992).

  87. Lam S. Detection of Dysplasia and Carcinoma In-situ Using Laser Induced Fluorescence. Japanese Chapter of the International Photodynamic Association, Asahikawa, Japan. (1992).

  88. Lam S. Detection of Early Lung Cancer by Fluorescence Imaging. Symposium on Innovations in Multimodality Therapy for Lung Cancer, University of Colorado Health Sciences Center, Denver, CO, USA (1992).

  89. Lam S. New developments in detection and localization of early lung cancer. Visiting Professor, Surgical Grand Rounds, Memorial Sloan-Kettering Cancer Centre, New York, NY, USA (1992).

  90. Lam S. Laser Therapy for Bronchogenic Carcinoma. Meet-the-Professor Seminar, American Thoracic Society International Conference, Miami, FL, USA (1992).

    91. 1991

  91. Korbelik M, Krosl G, Lam S, Chaplin DJ, Palcic B. Microlocalization of Photofrin in neoplastic lesions. Proc SPIE, 1426: 172-179. (1991).

  92. Lam S, Grafton C, Coy P, Voss N. A randomized comparative study of the safety and efficacy of photodynamic therapy using photofrin combined with palliative radiotherapy versus palliative radiotherapy alone in patients with inoperable obstructive non-small cell bronchogenic carcinoma. Proc SPIE, 1616:20-28. (1991).

  93. Palcic B, Lam S, MacAulay C, Hung J, Jaggi B, Radjinia M, Pon A, Profio AE. Lung Imaging fluorescence endoscope: development and experimental prototype. Proc SPIE 1448: 113-117. (1991).

  94. Profio AE, Balchum OJ, Lam S. Endoscopic fluorescence detection of early lung cancer. Proc SPIE 1426: 44-46. (1991).

    95. 1990

  95. Lam S, Hung J, Palcic B. Detection of lung cancer by ratio fluorometry with and without Photofrin II. Proc SPIE 1201:561-568. (1990).

Abstracts
Peer-Reviewed Papers | Non Peer-Reviewed Papers | Books (and Chapters) | Presentations and Symposium Proceedings | Abstracts | Patents | Other Forms of Publications

    2005

  1. Coe B, Lee E, Girard L, Gazdar A, Minna J, Lam S, MacAulay C, Tsao M, Lam W. . Fine mapping of SCLC tumors and cell lines by high resolution array CGH identifies novel alterations. Lung Cancer. 49(S2):S182, (2005).

  2. Lockwood W, Coe B, Garnis C, Minna J, MacAulay C, Lam S, Gazdar A, Lam W. . Whole genome comparison of SCLC and NSCLC cells identifies novel signature genetic alterations. Lung Cancer. 49(S2): S9, (2005).

  3. MacAulay C, Lonergan K, Garnis C, Coe B, Chi B, Guillaud M, Khojasteh M, LeRiche J, Lam S, Lam W. . Combining genome wide (BAC array CGH and Serial Analysis of gene expression) and quantitative microscopy for the analysis of lung cancer and its precursors. Lung Cancer. 49 (S2):S182, (2005).

    4. 2004

  4. Buys TPH, Lam S, MacAulay C, Ling V, Lam WL. . High Resolution Whole Genome Analysis Reveals Distinct Molecular Signatures for Vincristine-Resistant Ovarian Carcinoma Cell Lines. BCCA Cancer Conference, Vancouver BC, November 26-27, (in press) (2004).

  5. Carnis C, Davies J, Vucic E, Coe B, Ge Y, Gazdar G, Ramirez R, Shay J, Minna J, MacAulay C, Lam S, Lam W. . Whole genome Sub-Megabase Resolution Tiling (SMRT) array Comparative Genomic Hybridization (CGH) analysis of lung cancer and immortalized cell lines. 2004 Winter Lung Cancer SPORE Meeting. St. Pete's Beach, FL. February 13-14, (2004).

  6. Cox G, Miller J, Danek C, Leff A, Lam S. . Development of a procedural therapy for asthma: bronchial thermoplasty. 4th World Asthma Meeting, Bangkok, Thailand, February 16-19, (submitted) (2004).

  7. Cutz JC, Kaan P, Cleveland K, Lonergan K, MacAulay C, Lam S, Tsao MS, Lam W. . Expression profiles of WNT-signalling genes in lung cancer using microarray and SAGE databases. 93rd Annual USCAP Meeting, March 6-12,(submitted) (2004).

  8. Lam S, Lam D, Girard L, Lam W, Gazdar AF, Minna JD. . Gene expression profiling of bronchial brush epithelial cells from persons entered onto a budesonide chemoprevention trial identifies current from former smokers. 2004 Winter Lung Cancer SPORE Meeting, St. Pete's Beach, FL, February 13-14,(submitted) (2004).

  9. MacAulay C, Lonergan K, Marra M, Lam S, Lam W. . Serial Analysis of Gene Expression Profiles of Developmental Stages in Non-Small Cell Lung Carcinoma. CHEST 2004 (Supp) 125:97S. Thomas L. Petty Aspen Lung Conference 46th Annual Meeting, Aspen, Colorado, June 4-7, (2004).

    10. 2003

  10. Buys T, Garnis C, Coe B, MacAulay C, Lam S, Lam W. . Genetic Alterations on Chromosome 5p in Bronchial Squamous Carcinoma in Situ. BCCA Annual Conference. Vancouver BC, November 27-29. Abstract #59, Abstract Book pg. 17 (2003).

  11. Chan THW, MacAulay C, Lam W, Lam S, Lonergan K, Jones S, Marra M, Ng RT. . Evaluating Harvard's lung housekeeping genes using lung SAGE data. Lung Cancer 2003; 41(S2):S120, Abstract P-117. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  12. Chan THW, MacAulay C, Lam W, Lam S, Lonergan K, Ng RT. . Using the premutation test to analyze lung cancer SAGE libraries. Lung Cancer 2003; 41(S2):S120, Abstract P-116. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14 (2003).

  13. Cleveland KC, leRiche JC, MacAulay C, Lam S, Lam W. . Characterization of genetic alterations in lung cancer progression. BCCA Annual Cancer Conference, Vancouver BC, November 27-29. Abstract #105, Abstract Book pg. 29 (2003).

  14. Coe B, Garnis C, Ishkanian A, Lam S, MacAulay C, Lam W. . Tiling Resolution Array CGH Profiling of Chromosome Arms 3p and 5p in Lung Cancer Cell Lines. BCCA Annual Cancer Conference, Vancouver BC, November 27-29. Abstract #102, Abstract Book pg. 29 (2003).

  15. Coe BP, Garnis C, Krzywinski M, Marra M, MacAulay C, Lam S, Minna J, Lam W. . Fine mapping of breakpoints of genetic alterations on chromosome 3p in lung cancer by array CGH. Lung Cancer 2003; 41(S2):S168, Abstract P-302. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  16. Coe BP, Garnis C, Krzywinski M, Marra M, MacAulay C, Lam S, Tsao M, Minna J, Lam W. . Construction of high resolution CGH array for chromosome 5p and analysis of SCLC and adenocarcinoma cell lines. Lung Cancer 2003; 41(S2):S168, Abstract P-303. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  17. Garnis C, Coe B, Henderson LJ, Ishkanian A, Watson S, Marra M, Minna J, Lam S, MacAulay C, Lam w. . Identifying genetic alterations in pre-invasive lung cancers using chromosome arm-specific and genome-spanning comparative genomic hybridization arrays. Thomas L. Petty Aspen Lung Conference 46th Annual Meeting. Aspen, Colorado, June 4-7, CHEST 125 (5Suppl):104S-5S, (2003).

  18. Garnis C, MacAulay C, Lam S, Lam W. . Novel genetic alterations in preinvasive bronchial squamous cell carcinoma. Lung Cancer 2003; 41(S2):S52. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  19. Garnis C, MacAulay C, Lam S, Lam W. . Multiple but distinct regions of amplification on 8q identified by array comparative genomic hybridization. Lung Cancer 2003; 41(S2):S168, Abstract P-301. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  20. Garnis C, MacAulay C, Lam S, Lam WL. . The identification of novel genetic alterations in premalignant lung cancer biopsies. 10th Word Congress of Lung Cancer. Lung Cancer, Suppl. 2, 41:S52, Abstract O-173, (2003).

  21. Guan J, Cutz JC, Bayani J, Wang Y, Xue H, Wu R, Sutcliffe M, leRiche JC, English J, Bebb G, Gout PW, Squire J, Lam S, Wang YZ. . Establishment of a novel human lung cancer tissue xenograft model. BCCA Annual Cancer Conference, Vancouver BC. November 27-29. Abstract #104, Abstract Book pg. 29 (2003).

  22. Guan J, Wang Y, Zue H, Doxsee D, Sutcliffe M, Cutz JC leRiche JC, Bebb G, Gout PW, Lam S, Wang YZ. . Potential use for sulfasalazine in lung cancer therapy. BCCA Annual Cancer Conference, Vancouver BC, November 27-29 Abstract #104, Abstract Book pg. 29 (2003).

  23. Henderson LJ, Coe B, Minna J, Lam S, MacAulay C, Lam W. . High resolution array CGH detects two regions of amplification on chromosome arm 1p in small cell lung cancer cell lines. BCCA Annual Cancer Conference, Vancouver BC, November 27-29. Abstract #101, Abstract Book, pg. 29 (2003).

  24. Henderson LJ, Ishkanian A, Coe BP, Garnis C, Marra M, Minna J, Lam S, MacAulay C, Lam W. . Identification of regions of DNA alteration on chromosome arm 1p in NSCLC and SCLC. Lung Cancer 2003; 41(S2):S167, Abstract P-300. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  25. Huang Z, McWilliams A, Lam S, Lui H, Zeng H. . Near-infrared raman spectroscopy for optical diagnosis of lung cancer. Lung Cancer 2003; 41(S2):S50. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  26. Huang Z, McWilliams A, Lui H, McLean DI, Lam S, Zeng H. . Near-infrared raman spectroscopy for lung cancer diagnosis. BCCA Annual Cancer Conference, Vancouver BC, November 28-29, Abstract 98, Abstract Book pg. 28 (2003).

  27. Ishkanian A, Watson S, Malloff C, Coe B, DeLeeuw R, Krzywinski M, Marra M, MacAulay C, Lam W. . Construction of a DNA microarray with complete coverage of the human genome. Lung Cancer 2003; 41(S2):S60, Abstract O-203. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  28. Jones S, Ruzanov P, MacAulay C, Lam W, Lonergan K, Lam S, Zuyderduyn S, Schein J, Oveisi M, Varhol R, Rusaw S, Schnerch A, Khattra J, Thomson J, Humphries K, Eaves C, Ling V, Marra M. . High-throughput serial analysis of gene expression profiling of cancers. Advances in Genome Biology and Technology, Marco Island, FL, USA, February 5-8, (2003).

  29. Lam S, McWilliams A, leRich JC, MacAulay C, Gazdar AF. . Phase II trials of promising chemopreventive agents. Lung Cancer 2003; 41(S3):S56. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  30. Lam W, Lonergan K, Zuyderduyn S, Shein J, Tsao M, IeRiche JC, Jones S, Marra M, MacAulay C, Lam S. . Gene expression profiles of developmental stages of non-small cell lung carcinoma. 4th International SAGE Meeting, Amsterdam, Netherlands, January 17-19, (2003).

  31. Lonergran KM, Shadeo A, Kim JH, Chi B, leRiche J, Jones S, Tsao M, Marra M, MacAulay C, Lam W, Lam S. . Gene expression profiles of developmental stages of non-small cell lung carcinoma. Lung Cancer 2003; 41(S2):S123, Abstract P-126. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  32. McWilliams S, Mayo J, MacDonald S, leRiche JC, Palcic B, Lam S. . An alternative approach to lung cancer screening. Lung Cancer 2003; 41(S2):S41. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  33. Ruzanov P, MacAulay C, Lonergan K, Lam S, Lam W, Marra M, Jones S. . Deriving the transformation events in tumorgenesis using data from Serial Analysis of Gene Expression. Lung Cancer 2003; 41(S2):S122, Abstract P-125. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

  34. Tichelaar JW, Zhang Y, leRiche JC, Lam S, Anderson MW. . Activation of the AKT/NF-KB signalling axis in developing lung neoplasia. Thomas L. Petty Aspen Lung Conference 46th Annual Meeting, Aspen, Colorado, June 4-7, (2003).

  35. Zeng H, Petek M, Tercelj Zorman M, McWilliams A, Palcic B, Lam S. . Integrated endoscopy system for simultaneous imaging and spectroscopy for early lung cancer detection. BCCA Annual Cancer Conference, Vancouver BC, November 28-29, Abstract 99, Abstract Book pg. 28 (2003).

  36. Zuyderduyn SD, Oveisi M, Rusaw S, Varhol R, Ruzanov P, Lam W, Lam S, Lonergan K, MacAulay C, Siddiqui A. . Exploring the molecular basis of non-small cell early-stage lung cancer with the DISCOVERY platform. Lung Cancer 2003; 41(S2):S129, Abstract P-155. 10th World Congress of Lung Cancer, Vancouver, BC, Canada, August 10-14, (2003).

    37. 2002

  37. Coe B, Ishkanian A, Garnis C, Cleveland K, Marra M, MacAulay C, Lam S, Lam WL. . Construction of a BAC array spanning chromosome arm 3jp. 3rd Annual Pathology Day Gala, Vancouver, BC, Canada, (2002).

  38. Coe B, Ishkanian A, Malloff C, Watson S, deLeeuw R, Garnis C, Marra M, MacAulay C, Lam S, Lam W. . Cancer Genomics, Sub-project: Array CGH technology development. Genome British Columbia Meeting, Vancouver, BC, Canada, (2002).

  39. Henderson LJ, Ishkanian A, Cleveland K, Lam S, Marra M, MacAulay C, Lam W. . An array of human bacterial artificial chromosome (BAC) clones spanning chromosome arm 1p. 3rd Annual Pathology Day, Vancouver, BC, Canada, (2002).

  40. Lam S. . Role of autofluorescence bronchoscopy in screening patients at high risk for lung cancer. Proceedings of the 1st International Lung Cancer Conference, Beijing, China, October 27-30, (2002).

    41. 2001

  41. Guillaud M, MacAulay C, Korbelik J, Dawe C, leRiche J and Lam S. . Architectural analysis of bronchial intra-epithelial lesions: A stochastic approach to standardize architectural features based on a homogenous poison process. 7th Congress of the European Society for Analytical Cellular Pathology April 1-5, Caen, France, Abstract J003, pg 41 (2001).

  42. Kemp R, Lam S, and MacAulay C. . Automatic segmentation of overlapping nuclei in lung biopsy images. 7th Congress of the European Society for Analytical Cellular Pathology, Caen, France, April 1-5, Abstract R030, pg72 (2001).

  43. MacAulay C, Guillaud M, leRiche J, Gazdar A, Dlugan A and Lam S. . Analysis of chemoprevention data combining the qualitative with the quantitative. SPIE 2001 Intl Symposium on Bios, January 19-26, San Jose, CA. 4260-36:153 (2001).

  44. MacAulay C, Guillaud M, leRiche J, Gazdar A, Lam S. . Combining the qualitative with the quantitative for the analysis of chemoprevention data. 7th Congress of the European Society for Analytical Cellular Pathology, April 1-5, Caen, France, Abstract A014, pg14 (2001).

  45. MacAulay C, Guillaud M, leRiche J, Lane P, Garner D, Palcic B, Lam S. Quantitative Microscopy and Optical Interrogation Techniques Applied to the Management of Early Cancers and Chemoprevention. CCPM Symposium Kelowna, BC, Canada, Abstract Book pg. 2, July 12th, 2001. (2001).

  46. McWilliams A, MacAulay C, leRiche J, Lam S. . Quantitative Fluorescence Imaging. IPA 8th World Congress of Photodynamic Medicine, Vancouver, BC. June 5-9, Abstract Book pg 40 (2001).

  47. McWilliams A, Mayo J, Muller N, Palcic B, English J, Lam S. . Combination of computer assisted sputum analysis and low dose spiral CT scan for lung cancer screening Chest 120(4):166S (2001).

  48. Zeng H, Lam S, Lui H, McLean D, Weiss A, MacAulay C. Optical Spectroscopy and Imaging for Early Cancer Detection, Localization, and Evaluation. CCPM Symposium Kelowna, BC, Canada, Abstract Book pg. 3, July 12, 2001. (2001).

    49. 2000

  49. Lam S, MacAulay C, leRiche JC, Palcic B. Quantitative Fluorescence Bronchoscopy. 11th World Congress for Bronchology, Yokohama, Japan, June 7-10, Abstract 342. (2000).

  50. Lam S, Palcic B, Garner D, Beveridge J, MacAulay C, leRiche JC, Coldman A. Lung cancer control in the new millennium. Lung Cancer 29(S2):145. (2000).

  51. MacAulay C, Guillaud M, leRiche JC, Dawe C, Gazdar A, Coldman A, Palcic B, Lam S, Dlugan A, Kemp R. Use of 2D to 3D quantitative microscopy in preinvasive lung cancer. Lung Cancer 29(S1)A864:252. (2000).

    52. 1999

  52. Guillaud M, Lam S, Klein-Parker H, Gazdar AF, Payne P, leRiche JC, Dawe C, Korbelik J, Palcic B, MacAulay C. Correlation of pathology, loss of heterozygosty, morphometry, and architecture indices in bronchial dysplastic lesions. Analytical Cellular Pathology 18:A064:25. (1999).

  53. Lam S. Session Chair, Conference of the Joint Working Group on Quantitative In vivo Functional Imaging in Oncology. US Public Health Service's Office on Women's Health and the National Cancer Institute, Arlington, Virginia, USA, January 6-8 (1999).

  54. Lam S. Detection and Localization of Early Lung Cancer by Fluorescence Bronchoscopy using the LIFE-Lung System The IASLC - WAB Joint International Conference on Lung Cancer and Thoraco-Pulmonology, Genoa, Italy, November 26-28 (1999).

  55. MacAulay C, Klein-Parker H, leRiche JC, Gazdar AF, Guillaud M, Dawe C, Payne P, Korbelik J, Palcic B, Lam S. Morphometric quantitation of bronchial biopsies as intermediate endpoint biomarkers for lung cancer chemoprevention. Analytical Cellular Pathology 18:A099:38. (1999).

    56. 1998

  56. Lam S. Photodynamic therapy in early stage non-small cell lung cancer. Satellite Symposium on Advances in the Treatment of early Lung Cancer, Varese, Italy, December 8 (1998).

  57. Lam S. Program Co-Chair and Hands-on workshop faculty on fluorescence bronchoscopy, American Association of Bronchology Annual Meeting, Post-graduate Course, American College of Chest Physicians, Toronto, ON, Canada, September 11 (1998).

    58. 1997

  58. Guilllaud M, Payne P, Lam S, LeRiche J, Gazdar A, & MacAulay C. Architectural analysis of bronchial precancerous lesions - A new diagnotic tool? 11th Int'l Cong on Diagnostic Quantitative Pathology, Siena, Italy, October 2-4, Page 107, 1997. (1997).

  59. Klein-Parker H, MacAulay C, Lam S, Dawe C, Payne P, & Palcic B. High resolution computer-assisted imaging of nuclear texture of bronchial biopsies cells as a surrogate endpoint for chemoprevention trials. Lung Cancer 18(a):191, Abstract 743 (1997).

  60. Lam S, leRiche JC, MacAulay C. . Laser-assisted bronchoscopy in the early detection and treatment of lung cancer. Lung Cancer;18(2):42 (1997).

  61. MacAulay C, Lam S, Gazdar A, LeRiche J, Dawe C, Payne P, & Palcic B. Morphometric quantification of bronchial biopsies. Lung Cancer 18(1):172, Abstract 673 (1997).

  62. MacAulay C, Lam S, LeRiche J, Gazdar A, Payne P, Dawe C, & Palcic B. Quantitative classification of bronchial intraepithelial neoplasm. Analyt Cell Pathol 13(2):62, Abstract 19 (1997).

  63. MacKinnon M, Payne P, MacAulay C, LeRiche J, Lee A, Astrop C, Palcic B & Lam S. Evaluation of sputum cytology collection methods. Lung Cancer 18(1):188, Abstract 733 (1997).

  64. Palcic B, Payne P, MacAulay C, Lam S, Garner D. The role of malignancy associated changes in quantitative pathology. 11th Int'l Cong on Diagnostic Quantitative Pathology, Siena, Italy, October 2-4, Page 59, 1997. (1997).

  65. Payne P, MacAulay C, Doudkine A, Lam S, Palcic B, Bechtel J, Ikeda N, Kato H, Kennedy T, Marek W, Nakhosteen J, Petty T, & Saccomanno G. Sputum cytology analysis by image cytometry and conventional microscopy classifier development. Lung Cancer 18(1):174, Abstract 674 (1997).

    66. 1996

  66. Ikeda N, MacAulay C, Lam S, Garner D, Konaka C, Kato H, & Palcic B. Use of high resolution cytometry in predicting the biologic behaviour of lung disease. Analyt Quant Cytol Histol 18(1):70, Abstract 52 (1996).

  67. MacAulay C, Payne P, Sebo T, Lam S, Garner D, Doudkine A, & Palcic B. Sputum cytology: Increasing the sensitivity through quantitative measures. SPIE B-18:83, 1996. (1996).

  68. MacAulay C, Payne P, Wilton D, Garner D, Doudkine A, Lam S & Palcic B. MACS: Field Cancerization or Signal Response? XVIII Congress of the International Society for Analytical Cytology, Rimini, Italy, April 13-18, Cytometry Suppl. Absract AC40, 1996. (1996).

  69. MacAulay C, Payne P, Wilton D, Lam S, Thiberville L, Palcic B. MAC: Some answers, more questions. Analyt Quant Cytol Histol 18(1):78, Abstract 67 (1996).

  70. Palcic B, Lam S, MacAulay C, & Garner D. Comprehensive management of lung cancer. Cancer Detection and Prevention 20(5):527, Abstract 478/205 (1996).

  71. Payne P, Thiberville L, MacAulay C, Lam S, LeRiche Jc, Palcic B. Quantitative microscopy of Feulgen stained bronchial biopsies detect loss of heterozygosity in pre-cancerous lesions. XVIII Congress of the International Society for Analytical Cytology, Rimini, Italy, April 13-18, Cytometry Suppl Abstract TB29, 1996. (1996).

    72. 1995

  72. Guillaud M, Marcelpoil R, Payne P, MacAulay C, Lam S & Palcic B. Multiscale cellular sociological analysis: Application to the bronchial epithelium. International Workshop on Information Processing in Cells and Tissues, Liverpool, England, September 6-8, 557-568. (1995).

    73. 1994

  73. Ikeda N, MacAulay C, Lam S, Garner D, Payne P, Kato H, Konaka C, Palcic B & Hayata Y: The use of high resolution cytometry in predicting biological behavior of T1 adenocarcinoma of the lung. Lung Cancer 11 (Suppl. 1):45, Abstract 173 (1994).

  74. Lam S, leRiche JC, MacAulay C, Palcic B. . Detection of early lung cancer and preneoplastic lesions. Lung Cancer Suppl 2;11:161-162 (1994).

  75. MacAulay C, Lam S. . Sputum cytology for the effective screening of early lung cancer. Lung Cancer Suppl 2;11:165-166 (1994).

  76. MacAulay C, Payne P, Lam S, Haskins D & Palcic B. Malignancy associated changes (MACs) in bronchial epithelial aspirates and biopsies. Lung Cancer 11 (Suppl. 1):46, Abstract 174 (1994).

  77. MacAulay C, Payne P, Lam S, Haskins D & Palcic B. Malignancy associated changes (MACs) in bronchial epithelial aspirates and biopsies. Analyt Cell Pathol 6(3):204, Abstract 057 (1994).

  78. MacAulay C, Qu J, Lam S, & Palcic B. Effects of measurement geometry on detected tissue fluorescence. 5th International Photodynamic Assoc. Biennial Meeting, Amelia Island, FL, USA, September 21-24 (1994).

  79. Payne P, Guillaud M, Palcic B, MacAulay C, LeRiche JC & Lam S: Combining nuclear features and syntactic structure features from bronchial biopsies for consistent objective grading. XVII Congress of the International Society for Analytical Cytology, Lake Placid, NY, October 16-21, 1994. Cytometry Supple 7:87, Abstract 504D. (1994).

  80. Payne PW, Lam S, LeRiche JC, MacAulay C, Ikeda N & Palcic B. Image cytometry: Prediction of progression and regression of dysplasia in bronchial biopsies. Analyt Cell Pathol 6(3):205, Abstract 060 (1994).

  81. Payne PW, Lam S, LeRiche JC, MacAulay C, Ikeda N & Palcic B. Predicting progression and regression of dysplastic lesion of the lung by quantitative microscopy. Lung Cancer 11 (Suppl.1):45, Abstract 172 (1994).

    82. 1993

  82. Lam S, MacAulay C, Korbelik M, Palcic B. Fluorescence imaging of pre-malignant and malignant tissues with and without photosensitizers. Biomedical Optics Symposium, Los Angeles, CA, USA, January 17 (1993).

  83. Lam S, MacAulay C, LeRiche JC, Nelems B, Vedal S. Detection of bronchial dysplasia and carcinoma in-situ in high risk populations using fluorescence bronchoscopy. Presented at XVII World Congress on Diseases of the Chest, June 13-18, Amsterdam, The Netherlands. Chest 1993; 103:261 S. (1993).

  84. MacAulay C, Lam S, Payne P, Palcic B. Malignancy associated changes in bronchial epithelial tissue. Annual Meeting of the Canadian Thoracic Society, Vancouver, BC, Canada, September 10-13 (1993).

  85. MacAulay C, Lam S, Payne P, Palcic B. Malignancy associated changes in epithelial cells from bronchial biopsies. Presented at XVII World Congress on Diseases of the Chest June 13-18, Amsterdam, The Netherlands, Chest 1993; 103:260 S. (1993).

  86. MacAulay C, Lam S, Payne P, Palcic B. . Malignancy associated changes in bronchial epithelial tissue. Clinical and Investigative Medicine Suppl;16:4, Abstract 759 (1993).

  87. MacAulay C, Lam S, Payne P, Palcic B. . Malignancy associated changes in bronchial epithelial cells in biopsies. Cytometry Suppl;6:84, Abstract 443 (1993).

  88. Payne PW, Lam S, Palcic B, MacAulay C. Diagnostic variation on bronchial biopsy specimens: differential diagnosis by quantitative features. XVI Congress of the international society for analytic cytology. Colorado Springs, Colorado, USA. March 21-26 (1993).

    89. 1992

  89. Dugan M, McCaughan J, York E, Lam S, Lang N, Goldberg M, Mohsenifar Z, et al. A multicenter Phase III trial of photodynamic therapy (PDT) versus Nd:YAG Laser in the treatment of endobronchial obstruction. International Conference on Photodynamic Therapy and Medical Laser Applications, Milan, Italy, June 25-27 (1992).

  90. Lam S, MacAulay C, Hung J, LeRiche JC, Profio AE, Pon A, McKinnon N, Radjinia M, Palcic B. Detection of dysplasia and carcinoma in situ by a lung imaging fluorescence endoscope. Lasers in Surgery and Medicine 4:164. (1992).

  91. Lam S, MacAulay C, LeRiche JC, Hung J, & Palcic B. Detection of bronchial inflammation, dysplasia and carcinoma in-situ using laser induced fluorescence. 7th World Congress for Bronchology and Bronchoesophagology, Rochester, Minnesota, USA, September 28 - October 2 (1992).

  92. Lam S, MacAulay C, LeRiche JC, Hung J, & Palcic B. Detection of bronchial inflammation, dysplasia and carcinoma in-situ using laser induced fluorescence. 11th Intl Cong Photobiol, p.182, Abstract S25-4, Kyoto, Japan, September 7-12 (1992).

  93. Lam S, MacAulay C, LeRiche JC, Hung J, Palcic B. Detection of bronchial inflammation and carcinoma in situ using laser induced fluorescence. 7th World Congress for Bronchoscopy and Broncho-esophagology, Rochester, Minn, USA, September 28 - October 2 (1992).

  94. Lam S, MacAulay C, LeRiche JC, Hung J, Palcic B. Detection of bronchial inflammation, dysplasia and carcinoma in situ using laser induced fluorescence. 11th International Congress on Photobiology, Kyoto, Japan, September 7-12 (1992).

  95. Palcic B, MacAulay C, LeRiche JC, Payne PW, & Lam S. Detection of early lung cancer using fluorescence bronchoscopy: Who should be examined? Japanese Chapter of the International Photodynamic Association, Asahikawa, Japan, September 5 (1992).

  96. Wong E, Grafton C, Wong F, Morris J, Goddard K, Yuen K, Lam S. Brachytherapy for obstructive bronchial tumors. 7th World Congress for Bronchology and Bronchoesophagology, Rochester, Minnesota, USA, September 28 - October 2 (1992).

    97. 1991

  97. Hung J, Lam S, Miller R, Palcic B. Laser induced autofluorescence of normal and malignant tissues. 11th Annual Meeting of the American Society for Laser Medicine & Surgery, San Diego, CA, USA, May 1 (1991).

  98. Korbelik M, Krosyl G, Lam S. Can photodynamic therapy be potentiated by immunotherapy? International Conference on Photodynamic Therapy and Laser Medicine, Beijing, China, October 15-17 (1991).

  99. Krosl G, Grulkey W, Lam S, Chaplin DJ, Korbelik M. Microlocalization of Photofrin and other photosensitizers in different types of solid tumors. Annual Meeting of the American Society for Photobiology. San Antonio, Texas. June 22-26 (1991).

  100. Lam S, Davis NL, Quenville, NF, Kluftinger AM, Hung J, Palcic B. Detection of squamous cell cancer and pre-cancerous lesions by fluorescence imaging in a new hamster cheek pouch model. International Conference on Photodynamic Therapy and Laser Medicine, Beijing, China, October 15-17 (1991).

  101. Lam S, Grafton C, Coy P, Voss N. A randomized comparative study of the safety and efficacy of photodynamic therapy using photofrin combined with palliative radiotherapy versus palliatrive radiotherapy alone in patients with inoperable obstructive non-small cell bronchogenic carcinoma. International Conference on Photodynamic Therapy and Laser Medicine, , Beijing, China, October 15-17 (1991).

  102. Lam S, Hung J, LeRiche JC, Vedal S, Kennedy S, Nelems B, MacAulay C, Palcic B. Detection of dysplasia and in-situ carcinoma by fluorescence imaging. 6th World Conference on Lung Cancer, Melbourne Australia, November 12 (1991).

  103. Lam S, MacAulay C, Hung J, LeRiche JC, Profio AE, Palcic B. Detection of early cancer by a Lung Imaging Fluorescence Endoscope. International Conference on Photodynamic Therapy and Laser Medicine, Beijing, China, October 15-17 (1991).

  104. Palcic B, Lam S, MacAulay C, Jaggi B, Radjinia M, & Ron A. A fluorescence lung imaging endoscope: Development of experimental prototype. SPIE 13:1448. (1991).

    105. 1990

  105. Hung J, Korbelik M, Lam S, Chaplin D, Simon GT, Palcic B. Localization of polyhematoporphyrin derivatives in tumors. American Society for Photobiology Meeting, June 16-20, Photochem Photobiol 1990; 51:13S. (1990).

  106. Hung J, Lam S, Jaggi B, Pon A, Palcic B. Localization of lung cancer by tissue autofluoresence. 56th Annual Meeting of American College of Physicians, p.108s (1990).

  107. Hung J, Lam S, Palcic B. Mechanism of early lung cancer detection by fluorescence bronchoscopy. IPA 3rd Biennial Meeting, July 17-21, (Abstract XV/3). (1990).

  108. Korbelik M, Chaplin DJ, Krosl G, Lam S, Durand RE, Olive PL, Palcic B. Tumor associated macrophages: Role in Photofrin II Tumor Localization. IPA 3rd Biennial Meeting, July 17-21, (Abstract XIV/4). (1990).

  109. Korbelik M, Hung J, Lam S, Palcic B. Cellular delivery and retention of Photofrin II. The role of interaction with human serum proteins. American Society for Photobiology Meeting, June 16-20, Photochem Photobiol, 1990;51:82s. (1990).

  110. Korbelik M, Hung J, Lam S, Palcic B. The role of plasma constituents in cellular uptake and retention of Photofrin II. Rad Res Soc 38th Ann Sci Mtg, New Orleans, LO, USA, April 7-12, (Abstract Es 12). (1990).

  111. Krosl G, Korbelik M, Chaplin D, Lam S, Palcic B. The role of macrophages in tumor-localizing properties of Photofrin II. American Society for Photobiology Meeting, June 16-20, Photchem Photobiol 1990; 51:51s. (1990).

  112. Lam S, Hung J, Jaggi B, Palcic B. Detection of early lung cancer by ratio fluorometry and ratio imaging. World Conference on Lung Health, Boston, MA, USA, May 20-24, 1990. (1990).

  113. Lam S, Hung J, Palcic B. Detection of lung cancer by ratio fluorometry with or without Photofrin II. 3rd Radiobiology Workshop, Penticton, BC, Canada, February 18-19 (1990).

  114. Lam S, Palcic B, Jaggi B, Hung J, Pon A, Profio AE. Lung imaging fluorescence endoscope (LIFE): applications of a clinical prototype. IPA 3rd Biennial Meeting, July 17-21, (Abstract XXIII/2). (1990).

  115. Palcic B, Jaggi B, Pon A, Fengler J, Lam S. Development of a lung imaging fluorescence endoscope. IEEE Eng Med Biol 12 Ann Int Conf, Philadelphia, PA, USA, November 1-4 (1990).

    116. 1989

  116. Hung J, Korbelik M, Lam S, Palcic B. The effect of low density lipoproteins on uptake and clearance of Photofrin II from cultured cells. Photochem Photobiol 49 (suppl): 78S. (1989).

  117. Kennedy SM, Vedal S, Muller H, Lam S, Chan-Yeung M. Airflow obstruction among asbestos exposed insulators associated with pleural thickening. Am Rev Respir Dis 139:A209. (1989).

  118. Korbelik M, Hung J, Lam S, Palcic B. The effect of low density lipoprotein on uptake of Photofrin II in cultured cells. Presented at the Thirty-Seventh Annual Meeting of the Radiation Research Society, Seattle, WA, USA. March 21 (1989).

  119. Lam S, Cote J, LeRiche J, Salari H, Al-Majed S, Chan H, Chan-Yeung M. Factors which determine the occurrence of asthma in atopic subjects. Am Rev Respir Dis 139 A326. (1989).

  120. Lam S, Coy P, Al-Majed S, Muller N, LeRiche J. Combined photodynamic therapy and radiotherapy versus radiotherapy alone in obstructive endobronchial tumors. Presented at the Thirty-Seventh Annual Meeting of the Radiation Research Society, Seattle, WA, USA, March 21 (1989).

  121. Lam S, Palcic B, McLean D, Fengler J, Jung J, Korbelik M, Profio AE. Localization of early lung cancer by fluorescence bronchoscopy without skin photosensitivity. Presented at the 6th World Congress for Bronchology, Kyoto, Japan, October 21 (1989).

    122. 1988

  122. Chan-Yeung M, Salari H, Tse KS, Lam S. The role of mediator release and bronchial responsiveness in allergen induced bronchoconstriction. J Allergy Clin Immunol 81:A326. (1988).

  123. Kinsella M, Lam S, Enarson D, Chan-Yeung M. Methacholine challenge testing in the assessment of chronic persistent cough. Am Rev Respir Dis 137:A331. (1988).

  124. Korbelik M, Hung J, Lam S, Palcic B. In vitro tumor model for estimation of HpD in small foci for fluorescence endoscopic apparatus measurements. Lasers Med Sci July A117. (1988).

  125. Lam S, Coy P, Muller N, LeRiche J, Al-Majed S, Laukkanen E, Fairey R, Hay J, Voss N. Photodynamic therapy and palliative radiotherapy versus palliative radiotherapy alone for obstructive endobronchial tumors. Lasers Med Sci, July A30. (1988).

  126. Lam S, Salari H, Tse KS, Chan-Yeung M. Mediator release after nasal airway challenge. J Allergy Clin Immunol 81:A450. (1988).

  127. McLean DI, Morton C, Lam S. The effect of nonopaque sunscreens on the visible light photosensitivity induced by Hematoporphyrin Derivative. Lasers Med Sci, July A451. (1988).

  128. McLean DI, Morton C, Lam S, Schreiber W. The effect of hydrochlorothiazide on the photosensitivity induced by hematoporphyrin derivative. Lasers Med Sci, July A452. (1988).

  129. Profio AE, Khoury TF, Lam S. Measurement of concentration of dihematoporphyrin ether in tissue. ICALE-O Proceedings. (1988).

    130. 1987

  130. Lam S, Salari H, Chan H, Chan-Yeung M. Mediator release following bronchial challenge in patients with red cedar asthma. Chest 92-945. (1987).

  131. Zwirewich CV, Muller NL, Lam S. CT and bronchoscopy in the evaluation of complete bronchial obstruction prior to photodynamic therapy. Radiology 165(P) Suppl:239. (1987).

    132. 1986

  132. Lam S, Miller R, Kostashuk E, LeRiche J. Photodynamic therapy of lung cancer: potential problems. The First International Conference on the Clinical Applications of Photosensitization for Diagnosis and Treatment,Tokyo, Japan, April 30 - May 2 (1986).

  133. Lam S, Muller NL, Miller RR, Kostashuk E, Szaz IJ, LeRiche J. Laser treatment of obstructive endobronchial tumors: factors which determine response. Lasers in Surgery and Medicine 6(2):186. (1986).

  134. Lam S, Salari H, Chan H, Chan-Yeung M. Role of leukotrienes in intrinsic asthma. Chest 89(6):500S. (1986).

  135. Lam S, Salari H, Chan H, Chan-Yeung M. Release of leukotrienes after antigen challenge in patients with bronchopulmonary aspergillosis. Chest 89(6):501S. (1986).

    136. 1985

  136. Lam S, Chan-Yeung M, LeRiche JC, Kijek K, Phillips D. Cellular changes in bronchial lavage fluids following late asthmatic reaction in patients with red cedar asthma. Am Rev Respir Dis 131:A42. (1985).

  137. Lam S, LeRiche JC, Chan-Yeung M, Kijek K, Phillips D. Bronchial lavage: Comparison of two methods. Am Rev Respir Dis 131:A9. (1985).

  138. Lam S, Olivotto IA, Kostashuk EC, LeRiche JC, Miller RR. Combined photodynamic therapy and radiotherapy in the treatment of endobronchial tumors. Fourth World Conference on Lung Cancer, Toronto, ON, Canada, August 25-30 (1985).

    139. 1984

  139. Enarson DA, Chan-Yeung M, Lam S, Vedal S, McCormack G. Does determination of bronchial reactivity add anything to prevalence studies of respiratory disease in the occupational setting? Am Rev Respir Dis 129(2):160. (1984).

  140. Lam S, Berry J, Kijek K, Chan H. Distribution of electrolyte and protein molecules in bronchoalveolar fluids of normal subjects and patients with asthma. NIH International Conference on Bronchoalveolar Lavage. Columbus, OH, USA, May 16 (1984).

  141. Lam S, Kus J, Kijek K, Chan-Yeung M. Lymphocyte subpopulations in bronchial lavage fluid of patients with Western Red Cedar Asthma. Am Rev Respir Dis 129(2):152. (1984).

  142. Lam S, LeRiche J, Kijek K, Phillips D. Factors influencing the composition of bronchial/bronchoalveolar lavage fluid. NIH International Conference on Bronchoalveolar Lavage. Columbus, OH, USA, May 16 (1984).

  143. Lam S, LeRiche J, Kijek K, Phillips D. Differential volume lavage - A novel technique to study the airway response of patients with asthma. Fourth World Congress of Bronchology, Rome, Italy, June (1984).

  144. Miller R, Churg A, Hutcheon M, Lam S. Pulmonary alveolar proteinosis and aluminum dust exposure. Am Rev Respir Dis 129(2):165. (1984).

    145. 1983

  145. Lam S, Denegri JF, Chan-Yeung M, Growe GH, Evelyn RG. Decreased fibrinolytic activity in patients with adult respiratory distress syndrome. Presented at the Royal College of Physicians and Surgeons Meeting in September (1983).

    146. 1982

  146. Lam S, Yeung M, Evelyn R, Kijek K, Denegri JF. Neutrophil chemotactic factor and chemotactic factor inactivator in patients with adult respiratory distress syndrome. Clin Invest Med (1982).

  147. Lam S, Yeung M, Salina F, Kijek K, Chan H. Specific IgE - antibodies and immune complexes in bronchial fluids of patients with Western Red Cedar Asthma. Chest 82:253-254. (1982).

    148. 1981

  148. Lam S, Burton J. Legionella longbeachae pneumonia: diagnosis by bronchial brushing. B.C. Thoracic Society Meeting (1981).

  149. Lam S, Chan-Yeung M. Types of asthmatic reaction and nonspecific bronchial reactivity in patients with asthma due to Western Red Cedar. Am Rev Respir Dis 4:45. (1981).

  150. Molm D, Lam S. Pre-operative assessment of patients undergoing upper abdominal surgery. B.C. Thoracic Society Meeting (1981).

    151. 1980

  151. Lam S, Chan-Yeung M, Abboud R. The comparison of flow volume curves with air and helium spirometry in epidemiologic health surveys. Am Rev Respir Dis 12:244. (1980).

    152. 1979

  152. David L, Lam S, Chan-Yeung M. Serum glucosaminidase levels in patients with red cedar asthma. Presented at the International Conference on Occupational Lung Disease, February (1979).

    153. 1978

  153. Abboud R, Lam S, Chan-Yeung M. Granulocyte elastase activity as a factor related to abnormal lung function in antitrypsin deficient subjects (MZ phenotypes). Am Rev Respir Dis 117:306. (1978).

  154. Chan-Yeung M, Lam S, Wong R. Nonspecific bronchial reactivity in occupational asthma. Am Rev Respir Dis 117:62. (1978).

Patents
Peer-Reviewed Papers | Non Peer-Reviewed Papers | Books (and Chapters) | Presentations and Symposium Proceedings | Abstracts | Patents | Other Forms of Publications

    2000

  1. Palcic B, MacAulay C, Harrison AS, Lam S, Payne P, Garner D, Doudkine A. System and method for automatically detecting malignant cells and cells having malignancy-associated changes.  European Patent No. EP1019699A1, July 20, 2000 (2000).

  2. Palcic B, MacAulay C, Lam S, Jaggi B. Apparatus and Method for Imaging Diseased Tissue Using Integrated Autofluorescence  European Patent No. 752825B1, September 20, 2000 (2000).

    3. 1998

  3. Palcic B,MacAulay C, Lam S, and Jaggi B. Endoscope having an integrated CCD sensor  US Patent #5827190, October 27, 1998 (1998).

    4. 1997

  4. MacAulay C, Palcic B, Lam S, and Jaggi B. A system and method for imaging diseased tissue using integrated autofluorescence (fluorescence/reflectance).  US Patent #5590660, January 7, 1997 (1997).

    5. 1996

  5. Palcic B, MacAulay C, Jaggi B, Lam S, Profio AE, and Hung J. Endoscopic Imaging System for Diseased Tissue  US Patent #5507287, April 16, 1996; Patent application filed: May 1991 (Canada), May 1991 (Japan); May 1992 (Europe).  European Patent No. 512965A1, November 11, 1992; European Patent No. 512965B1, July 24, 1996;  US Patent #5769792, June 23, 1998 (1996).

    6. 1995

  6. Lam S. Apparatus And Method For Imaging Diseased Tissue Using Integrated Autofluorescence European Patent 1995, U.S. Patent 1996 (1995).

Other Forms of Publications
Peer-Reviewed Papers | Non Peer-Reviewed Papers | Books (and Chapters) | Presentations and Symposium Proceedings | Abstracts | Patents | Other Forms of Publications

    1994

  1. Lam S. Autofluorescence Bronchoscopy Pulmonary Perspectives (1994).

    2. 1987

  2. Lam S, Chan-Yeung M. Occupational Asthma Medicine International 2:1536-1540 (1987).

  3. Lam S, Evans K. Laser therapy for endobronchial tumors B.C. Medical Journal 29(10):609-610 (1987).

    4. 1984

  4. Lam S, Chan-Yeung M. Management of acute asthma B.C. Medical Journal 26:655-658 (1984).
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