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 Cancer Imaging 
Mladen Korbelik

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Peer-Reviewed Papers

    2008

  1. Korbelik M, Cecic I, Merchant S, Sun J. Acute phase response induction by cancer treatment with photodynamic therapy. Int J Cancer. 122(6):1411-7. (2008).
     [View Abstract - PubMed 18033689]

  2. 2007

  3. Cecic, I., Minchinton, A.I. and Korbelik, M. The impact of complement activation on tumor oxygenation during photodynamic therapy Photochem. Photobiol. 83: 1049-1055, 2007. (2007).
     [View Abstract - PubMed 17880499]

  4. Korbelik, M. and Cooper, P.D.. Potentiation of photodynamic therapy of cancer by complement: ýthe effect of -inulin. Br. J. Cancer 96: 67-72 (2007).

  5. Merchant S, Sun J, Korbelik M. Dying cells program their expedient disposal: serum amyloid P component upregulation in vivo and in vitro induced by photodynamic therapy of cancer. Photochem Photobiol Sci. 6(12):1284-9. Epub 2007 Sep 18. (2007).
     [View Abstract - PubMed 18046483]

  6. Stott, B. and Korbelik, M.:. Activation of complement C3, C5, and C9 genes in tumors treated by photodynamic therapy. Cancer Immunology Immunotherapy 56(5):649-58, (2007).
     [View Abstract - PubMed 16947020]

  7. 2006

  8. Cecic I, Korbelik M. Deposition of complement proteins on cells treated by photodynamic therapy in vitro. J Environ Pathol Toxicol Oncol. 25(1-2):189-203. (2006).
     [View Abstract - PubMed 16566717]

  9. Cecic, I., Sun, J. and Korbelik, M.: . Role of complement anaphylatoxin C3a in photodynamic therapy-elicited engagement of neutrophils and other immune cells. Photochem. Photobiol., 82:558-562, (2006).
     [View Abstract - PubMed 16613513]

  10. Chen WR, Huang Z, Korbelik M, Nordquist RE, Liu H. Photoimmunotherapy for cancer treatment. J Environ Pathol Toxicol Oncol. 25(1-2):281-91. (2006).
     [View Abstract - PubMed 16566724]

  11. Korbelik M. PDT-associated host response and its role in the therapy outcome. Lasers Surg Med. 38(5):500-8. (2006).
     [View Abstract - PubMed 16634073]

  12. Korbelik, M. and Sun, J.:. Photodynamic therapy-generated vaccine for cancer therapy. Cancer Immunology Immunotherapy 55(8):900-909, (2006).
     [View Abstract - PubMed 16215717]

  13. 2005

  14. Cecic I, Serrano K, Gyongyossy-Issa M, Korbelik M. Characteristics of complement activation in mice bearing Lewis lung carcinomas treated by photodynamic therapy. Cancer Lett. 225(2):215-23. Epub 2005 Jan 13. (2005).
     [View Abstract - PubMed 15978326]

  15. Chen WR, Korbelik M, Bartels KE, Liu H, Sun J, Nordquist RE. Enhancement of laser cancer treatment by a chitosan-derived immunoadjuvant. Photochem Photobiol. 81(1):190-5. (2005).
     [View Abstract - PubMed 15535737]

  16. Huang Z, Lui H, McLean DI, Korbelik M, Zeng H. Raman spectroscopy in combination with background near-infrared autofluorescence enhances the in vivo assessment of malignant tissues. Photochem Photobiol. 81(5):1219-26. (2005).
     [View Abstract - PubMed 15869327]

  17. Korbelik M, Sun J, Cecic I. Photodynamic therapy-induced cell surface expression and release of heat shock proteins: relevance for tumor response. Cancer Res. 65(3):1018-26. (2005).
     [View Abstract - PubMed 15705903]

  18. Korbelik M, Sun J, Cecic I. Photodynamic therapy-induced cell surface expression and release of heat shock proteins: relevance for tumor response. Cancer Res. 65(3):1018-26. (2005).
     [View Abstract - PubMed 15705903]

  19. 2004

  20. Korbelik M, Sun J, Cecic I, Serrano K. Adjuvant treatment for complement activation increases the effectiveness of photodynamic therapy of solid tumors. Photochem Photobiol Sci. 3(8):812-6. Epub 2004 Apr 2. (2004).
     [View Abstract - PubMed 15295639]

  21. 2003

  22. Korbelik M, Sun J, Payne PW. Activation of poly(adenosine diphosphate-ribose) polymerase in mouse tumors treated by photodynamic therapy. Photochem Photobiol 78(4):400-6. (2003).
     [View Abstract - PubMed 14626669]

  23. Korbelik M, Sun J, Zeng H. Ischaemia-reperfusion injury in photodynamic therapy-treated mouse tumours. Br J Cancer 88(5):760-6. (2003).
     [View Abstract - PubMed 12618887]

  24. 2002

  25. Canti G, De Simone A, Korbelik M. Photodynamic therapy and the immune system in experimental oncology. Photochem Photobiol Sci 1(1):79-80. (2002).
     [View Abstract - PubMed 12659153]

  26. Cecic I, Korbelik M. Mediators of peripheral blood neutrophilia induced by photodynamic therapy of solid tumors. Cancer Lett 183(1):43-51. (2002).
     [View Abstract - PubMed 12049813]

  27. Sun J, Cecic I, Parkins CS, Korbelik M. Neutrophils as inflammatory and immune effectors in photodynamic therapy-treated mouse SCCVII tumours. Photochem Photobiol Sci 1(9):690-5. (2002).
     [View Abstract - PubMed 12665307]

  28. Zeng H, Korbelik M, McLean DI, MacAulay C, Lui H. Monitoring photoproduct formation and photobleaching by fluorescence spectroscopy has the potential to improve PDT dosimetry with a verteporfin-like photosensitizer. Photochem Photobiol 75(4):398-405. (2002).
     [View Abstract - PubMed 12003130]

  29. 2001

  30. Bissonnette R, Zeng H, McLean DI, Korbelik M, Lui H. Oral aminolevulinic acid induces protoporphyrin IX fluorescence in psoriatic plaques and peripheral blood cells. Photochem Photobiol 74(2):339-45. (2001).
     [View Abstract - PubMed 11547574]

  31. Cecic I, Parkins CS, Korbelik M. Induction of systemic neutrophil response in mice by photodynamic therapy of solid tumors. Photochem Photobiol 74(5):712-20. (2001).
     [View Abstract - PubMed 11723800]

  32. Korbelik M, Sun J. Cancer treatment by photodynamic therapy combined with adoptive immunotherapy using genetically altered natural killer cell line. Int J Cancer 93(2):269-74. (2001).
     [View Abstract - PubMed 11410876]

  33. Korbelik M, Sun J, Posakony JJ. Interaction between photodynamic therapy and BCG immunotherapy responsible for the reduced recurrence of treated mouse tumors. Photochem Photobiol 73(4):403-9. (2001).
     [View Abstract - PubMed 11332036]

  34. 2000

  35. Korbelik M, Parkins CS, Shibuya H, Cecic I, Stratford MR, Chaplin DJ. Nitric oxide production by tumour tissue: impact on the response to photodynamic therapy. Br J Cancer 82(11):1835-43. (2000).
     [View Abstract - PubMed 10839299]

  36. 1999

  37. Korbelik M, Cecic I. Contribution of myeloid and lymphoid host cells to the curative outcome of mouse sarcoma treatment by photodynamic therapy. Cancer Lett 137(1):91-8. (1999).
     [View Abstract - PubMed 10376798]

  38. Korbelik M, Dougherty GJ. Photodynamic therapy-mediated immune response against subcutaneous mouse tumors. Cancer Res 59(8):1941-6. (1999).
     [View Abstract - PubMed 10213504]

  39. 1998

  40. Dougherty TJ, Gomer CJ, Henderson BW, Jori G, Kessel D, Korbelik M, Moan J, Peng Q. Photodynamic therapy. J Natl Cancer Inst 90(12):889-905. (1998).
     [View Abstract - PubMed 9637138]

  41. Korbelik M, Cecic I. Enhancement of tumour response to photodynamic therapy by adjuvant mycobacterium cell-wall treatment. J Photochem Photobiol B 44(2):151-8. (1998).
     [View Abstract - PubMed 9757597]

  42. Korbelik M, Naraparaju VR, Yamamoto N. The value of serum alpha-N-acetylgalactosaminidase measurement for the assessment of tumour response to radio- and photodynamic therapy. Br J Cancer 77(6):1009-14. (1998).
     [View Abstract - PubMed 9528849]

  43. 1997

  44. Korbelik M, Naraparaju VR, Yamamoto N. Macrophage-directed immunotherapy as adjuvant to photodynamic therapy of cancer. Br J Cancer 75(2):202-7. (1997).
     [View Abstract - PubMed 9010027]

  45. 1996

  46. Korbelik M. Induction of tumor immunity by photodynamic therapy. J Clin Laser Med Surg 14(5):329-34. (1996).
     [View Abstract - PubMed 9612200]

  47. Korbelik M, Krosl G. Photofrin accumulation in malignant and host cell populations of various tumours. Br J Cancer 73(4):506-13. (1996).
     [View Abstract - PubMed 8595166]

  48. Korbelik M, Krosl G, Krosl J, Dougherty GJ. The role of host lymphoid populations in the response of mouse EMT6 tumor to photodynamic therapy. Cancer Res 56(24):5647-52. (1996).
     [View Abstract - PubMed 8971170]

  49. Krosl G, Korbelik M, Krosl J, Dougherty GJ. Potentiation of photodynamic therapy-elicited antitumor response by localized treatment with granulocyte-macrophage colony-stimulating factor. Cancer Res 56(14):3281-6. (1996).
     [View Abstract - PubMed 8764122]

  50. 1995

  51. Korbelik M, Krosl G. Accumulation of benzoporphyrin derivative in malignant and host cell populations of the murine RIF tumor. Cancer Lett 97(2):249-54. (1995).
     [View Abstract - PubMed 7497470]

  52. Korbelik M, Krosl G. Photofrin accumulation in malignant and host cell populations of a murine fibrosarcoma. Photochem Photobiol 62(1):162-8. (1995).
     [View Abstract - PubMed 7638261]

  53. Krosl G, Korbelik M, Dougherty GJ. Induction of immune cell infiltration into murine SCCVII tumour by photofrin-based photodynamic therapy. Br J Cancer 71(3):549-55. (1995).
     [View Abstract - PubMed 7880738]

  54. 1994

  55. Korbelik M, Krosl G. Cellular levels of photosensitisers in tumours: the role of proximity to the blood supply. Br J Cancer 70(4):604-10. (1994).
     [View Abstract - PubMed 7917904]

  56. Korbelik M, Krosl G. Enhanced macrophage cytotoxicity against tumor cells treated with photodynamic therapy. Photochem Photobiol 60(5):497-502. (1994).
     [View Abstract - PubMed 7800721]

  57. Krosl G, Korbelik M. Potentiation of photodynamic therapy by immunotherapy: the effect of schizophyllan (SPG). Cancer Lett 84(1):43-9. (1994).
     [View Abstract - PubMed 8076362]

  58. Meng, G., James, B.R., Skov, K.A. and Korbelik, M.. Porphyrin chemistry pertaining to the design of anti-cancer drugs; part 2, the synthesis and in vitro tests of water-soluble porphyrins containing, in meso-positions, the functional groups: 4 methylpyridinium, or 4-sulfonatophenyl, in combination with phenyl, 4-pyridyl, 4-nitrophenyl or 4-aminophenyl Can. J. Chem. 72:2447-2457 (1994).

  59. 1993

  60. Korbelik M. Cellular delivery and retention of photofrin: III. Role of plasma proteins in photosensitizer clearance from cells. Photochem Photobiol 57(5):846-50. (1993).
     [View Abstract - PubMed 8337259]

  61. Korbelik M. Distribution of disulfonated and tetrasulfonated aluminum phthalocyanine between malignant and host cell populations of a murine fibrosarcoma. J Photochem Photobiol B 20(2-3):173-81. (1993).
     [View Abstract - PubMed 7505820]

  62. Korbelik M, Krosl G, Adomat H, Skov KA. The effect of differentiation on photosensitizer uptake by HL60 cells. Photochem Photobiol 58(5):670-5. (1993).
     [View Abstract - PubMed 8284322]

  63. Walter, P., Korbelik, M., Spadinger, I. and Skov, K.. Investigations into mechanisms of the interaction between platinum complexes and irradiation at low (~2Gy) doses in hypoxic cells I. The role of single strand breaks. Radiat. Oncol. Invest. 1:137-147 (1993).

  64. 1992

  65. Korbelik M. Low density lipoprotein receptor pathway in the delivery of Photofrin: how much is it relevant for selective accumulation of the photosensitizer in tumors? J Photochem Photobiol B 12(1):107-9. (1992).
     [View Abstract - PubMed 1531856]

  66. Korbelik M. Cellular delivery and retention of photofrin: II. The effects of human versus mouse and bovine serum. Photochem Photobiol 56(3):391-7. (1992).
     [View Abstract - PubMed 1438575]

  67. 1991

  68. Korbelik M, Hung J. Cellular delivery and retention of Photofrin II: the effects of interaction with human plasma proteins. Photochem Photobiol 53(4):501-10. (1991).
     [View Abstract - PubMed 1830394]

  69. Korbelik M, Krosl G, Chaplin DJ. Photofrin uptake by murine macrophages. Cancer Res 51(9):2251-5. (1991).
     [View Abstract - PubMed 1826630]

  70. Korbelik M, Krosl G, Olive PL, Chaplin DJ. Distribution of Photofrin between tumour cells and tumour associated macrophages. Br J Cancer 64(3):508-12. (1991).
     [View Abstract - PubMed 1832927]

  71. Korbelik, M.. Photosensitizers in photodynamic therapy (a review) Periodicum Biologorum, 93(4):563-574 (1991).

  72. 1990

  73. Korbelik M, Hung J, Lam S, Palcic B. The effects of low density lipoproteins on uptake of Photofrin II. Photochem Photobiol 51(2):191-6. (1990).
     [View Abstract - PubMed 2139730]

  74. Korbelik M, Suhar A, Osmak M, Skrk J, Turk V. Dynamics of postirradiation intracellular cysteine and aspartic proteinases profiles in proliferating and nonproliferating mammalian cells. Strahlenther Onkol 166(6):402-4. (1990).
     [View Abstract - PubMed 2194305]

  75. Lam S, Palcic B, McLean D, Hung J, Korbelik M, Profio AE. Detection of early lung cancer using low dose Photofrin II. Chest 97(2):333-7. (1990).
     [View Abstract - PubMed 2137075]

  76. 1989

  77. Korbelik M, Skov KA. Inactivation of hypoxic cells by cisplatin and radiation at clinically relevant doses. Radiat Res 119(1):145-56. (1989).
     [View Abstract - PubMed 2756105]

  78. Korbelik M, Skrk J, Poljak-Blazi M, Suhar A, Boranic M. The effects of human kallikrein and aprotinin on nonmalignant and malignant cell growth. Adv Exp Med Biol 247B:675-80. (1989).
     [View Abstract - PubMed 2481955]

  79. Osmak M, Korbelik M, Suhar A, Skrk J, Turk V. The influence of cathepsin B and leupeptin on potentially lethal damage repair in mammalian cells. Int J Radiat Oncol Biol Phys 16(3):707-14. (1989).
     [View Abstract - PubMed 2646261]

  80. Osmak M, Sirotkovic M, Levanat S, Korbelik M, Pavelic K. Substance immunologically cross-reactive with insulin (SICRI) stimulates cell division. Oncology 46(1):54-7. (1989).
     [View Abstract - PubMed 2644605]

  81. Palcic B, Korbelik M, Trotter M, Revesz L. Oxygen enhancement ratio of fractionated regimens in vitro. Radiat Res 117(3):409-18. (1989).
     [View Abstract - PubMed 2928466]

  82. Skov KA, Korbelik M, Palcic B. The interaction of trans-DDP [PtCl2(NH3)2] with low doses of radiation in mammalian cells. Int J Radiat Oncol Biol Phys 16(5):1281-4. (1989).
     [View Abstract - PubMed 2715080]

  83. 1988

  84. Korbelik M, Osmak M, Suhar A, Skrk J, Turk V, Petrovic D. Modification of potentially lethal damage repair by some intrinsic intra- and extracellular agents: I. Proteinases and proteinase inhibitors. Int J Radiat Biol 54(3):461-74. (1988).
     [View Abstract - PubMed 2900866]

  85. Korbelik M, Skrk J, Suhar A, Turk V. The role of proteinases, interferons and hormones in proliferative activities of nonmalignant and malignant cells. Neoplasma 35(5):555-63. (1988).
     [View Abstract - PubMed 2464142]

  86. Korbelik, M., Osmak, M., Arezina, R., Suhar, A., Skrk, J. and Turk, V.. Proteinase inhibitors as radioprotectors in vitro Studia Biophysica 123:5-11 (1988).

  87. Poljak-Blazi M, Korbelik M, Boranic M. [Growth of bone marrow cells in vitro] Lijec Vjesn 110(3-4):97-9. (1988).
     [View Abstract - PubMed 3398693]

  88. 1987

  89. Korbelik, M. and Petrovic, D.. The role of glucose and the Crabtree effect in cytotoxicity of nitroheterocyclic drugs Period. Biol. 89:165-172 (1987).

  90. Krizanac-Bengez, L., Korbelik, M., Poljak-Blazi, M., Kardum, I., Sustercic, D., Jaksic, B., Nemet, D. and Boranic, M.. Clonal growth of human bone marrow cells in semisolid medium with methylcellulose: Choosing the optimal conditions Bilten Hematol. Transf. 15:9-21 (1987).

  91. 1986

  92. Korbelik M, Skrk J, Schauer P, Suhar A, Turk V, Likar M. The effect of intracellular proteinases on transformation of human lymphocytes. Adv Exp Med Biol 198 Pt B:113-20. (1986).
     [View Abstract - PubMed 3544722]

  93. Korbelik, M., Skrk, J., Suhar, A., Schauer, P. and Turk, V.. The role of intracellular proteinases in proliferative activities of mammalian cells in culture Period. Biol. 88:142-144 (1986).

  94. 1985

  95. Korbelik M, Palcic B, Skarsgard LD. Bleomycin and misonidazole cytotoxicity. Br J Cancer 51(4):499-504. (1985).
     [View Abstract - PubMed 2579666]

  96. 1984

  97. Korbelik, M., Schauer, P., Suhar, A., Skrk, J., Turk, V. and Likar, M.. The role of intracellular proteinases in growth cycle of eukaryotic cells Farm. Vestn. 35:233-237 (1984).

  98. 1983

  99. Korbelik, M.. Development of pion radiotherapy at TRIUMF Radiol. Iugosl. 17:609-616 (1983).

  100. Korbelik, M.. Differential cytotoxicity of nitroaromatic drugs used in Yugoslavia Radiol. Iugosl. 17:59-64 (1983).

  101. 1982

  102. Kopitar M, Drobnic-Kosorok M, Babnik J, Brzin J, Turk V, Korbelik M, Batista U, Svetina S, Skrk J, Giraldi T, Sava G. Biochemical and biological characteristics of leucocyte proteinase inhibitors. Adv Exp Med Biol 141:233-45. (1982).
     [View Abstract - PubMed 7090916]

  103. Korbelik M, Palcic B, Skov K, Skarsgard L. Misonidazole and potentially lethal damage. Int J Radiat Oncol Biol Phys 8(3-4):461-4. (1982).
     [View Abstract - PubMed 7201990]

  104. Skov KA, Korbelik M, Palcic B, Skarsgard LD. Energy and misonidazole toxicity: the effects of 5-thio-D-glucose. Int J Radiat Oncol Biol Phys 8(3-4):697-700. (1982).
     [View Abstract - PubMed 7107401]

  105. 1981

  106. Korbelik M, Palcic B, Skarsgard LD. Radiation-enhanced cytotoxicity of misonidazole. Radiat Res 88(2):343-53. (1981).
     [View Abstract - PubMed 7302140]

  107. Korbelik, M., Skrk, J. and Crnivec, R.. Study of in vitro transformation of BHK cells treated with metronidazole and tinidazole in hypoxia Radiol. Iugosl. 15:97-101 (1981).

  108. 1980

  109. Crnivec, R. and Korbelik, M.. Study of radiosensitizing effect of metronidazole on asynchronous cell cultures in aerobic and hypoxic conditions Radiol. Iugosl. 14:93-100 (1980).

  110. Korbelik M. [Cytotoxicity of nitroaromatic compounds] Arh Hig Rada Toksikol 31(3):227-46. (1980).
     [View Abstract - PubMed 7192543]

  111. Korbelik M, Horvat D. The mutagenicity of nitroaromatic drugs: effect of metronidazole after incubation in hypoxia in vitro. Mutat Res 78(2):201-7. (1980).
     [View Abstract - PubMed 7393247]

  112. 1976

  113. Korbelik M. [Various aspects of the effect of ultraviolet radiation on animal cells] Arh Hig Rada Toksikol 27(3):243-63. (1976).
     [View Abstract - PubMed 999529]

  114. 1975

  115. Han A, Korbelik M, Ban J. DNA-to-protein cross-linking in synchronized HeLa cells exposed to ultra-violet light. Int J Radiat Biol Relat Stud Phys Chem Med 27(1):63-74. (1975).
     [View Abstract - PubMed 1078818]

  116. 1974

  117. Ban, J., Han, A. and Korbelik, M.. An improved method for cell cycle analysis of synchronized mammalian cells (HeLa-FA3) Iugoslav. Physiol. Pharmacol. Acta 10:173-181 (1974).

Non Peer-Reviewed Papers

    In Press

  1. Korbelik, M. (invited paper): . Advances in the understanding of host response associated with tumor PDT. Proc. SPIE 6438 (In Press).

  2. 2006

  3. Korbelik, M., (invited paper) Merchant, S., Stott, B., Cecic, I., Payne, P., and Sun, J.: . Acute phase response induced following tumor treatment by photodynamic therapy: relevance for the therapy outcome. Proc. SPIE 6087: 1-7, (2006).

  4. 2005

  5. Chen, W.R., Bartels, K.E., Korbelik, M., Liu, H., and Nordquist, R.E.: . Synergistic effects of laser and adjuvant therapies for cancer: progress in the development of novel cancer treatment methods using combinations of photothermal, photochemical, immunotherapy, and chemotherapy. Proc. SPIE 5695: 1-6, (2005).

  6. Korbelik, M. and Dougherty, G.J.: . Complement activation approaches for use in conjunction with PDT for cancer treatment. Proc. SPIE 5695: 17-26, (2005).

  7. 2004

  8. Chen, W., Jeong, S., Korbelik, M., Bartels, K.E., Martin, S.D., Sun, J., Liu, H., Nordquist, R.E.: . Enhancement of glycated chitosan in laser cancer treatment. SPIE 5319:80-86, (2004).

  9. Korbelik, M. (invited paper): . Role of Toll-like receptors in photodynamic therapy-elicited host response. SPIE 5319:87-95, (2004).

  10. 2003

  11. Korbelik, M. (invited paper) and Sun, J.: . Progress in the development of photodynamic therapy-generated cancer vaccines. SPIE 4961:10-17, (2003).

  12. 2001

  13. Korbelik, M. (invited paper), Cecic, I., and Sun, J.. Relevance of PDT-induced inflammatory response for the outcome of photodynamic therapy Proceedings of SPIE 4257:19-24, 2001. (2001).

  14. Korbelik, M. (invited paper), Sun, J., Cecic, I., and Dougherty, G.. The role of inflammatory cytokines in the response of solid cancers to photodynamic therapy SPIE 4248:107-113 (2001).

  15. 2000

  16. Korbelik, M. (invited paper) . Immunotherapy regimens for combination with photodynamic therapy aimed at eradication of solid cancers SPIE 3914:16-24 (2000).

  17. 1999

  18. Korbelik, M. . Antitumor immune reaction elicited by photodynamic therapy SPIE 3601:82-88 (1999).

  19. Korbelik, M., Cecic, I., Sun, J., Chaplin D.J. (invited paper). Examples of adjuvant treatment enhancing the antitumor effect of photodynamic therapy. SPIE 3592:65-72 (1999).

  20. 1998

  21. Korbelik, M., Shibuya, H., Cecic, I. . +Relevance of nitric oxide to the response of tumors to photodynamic therapy SPIE 3247:68-74 (1998).

  22. Korbelik, M., Sun, J... Cancer treatment by photodynamic therapy combined with NK cell line based adoptive immunotherapy SPIE 3254:4-11 (1998).

  23. 1996

  24. Korbelik, M., Krosl, G., Krosl, J. and Dougherty, G. (Invited paper). Modulation of tumor response to photodynamic therapy in severe combined immunodeficient (SCID) mice by adoptively transferred lymphoid cells SPIE 2675:156-162 (1996).

  25. 1995

  26. Korbelik, M. and Krosl, G.. Tumor associated macrophages (not tumor cells) are the determinants of photosensitizer tumor localization SPIE 2371:344-346 (1995).

  27. Korbelik, M. and Krosl, G. (Invited paper). Distinctive role of activated tumor associated macrophages in photosensitizer accumulation SPIE 2392:129-135 (1995).

  28. Krosl, G., Korbelik, M., Krosl, J. and Dougherty, G.J.. Potentiation of photodynamic therapy by granulocyte-macrophage colony stimulating factor immunotherapy SPIE 2371:347-350 (1995).

  29. 1994

  30. Korbelik, M. and Krosl, G.. Distribution of photosensitizers between tumor cells and tumor infiltrating host cells SPIE 2078:389-396 (1994).

  31. 1993

  32. Korbelik, M., Krosl, G. and Chaplin, D.J.. Can PDT be potentiated by immunotherapy? SPIE 1616:192-198 (1993).

  33. Korbelik, M., Matisic, J. and Krosl, G.. Electron microscopy study of tumor destruction by photodynamic therapy SPIE 1881:305-312 (1993).

  34. Lam, S., MacAulay, C., LeRiche, J.C., Qu, J., Krosl, G., Zeng, H., Korbelik, M., Palcic, B.. Fluorescence imaging of pre-malignant and malignant tissues with and without photosensitizers SPIE 1881:160-167 (1993).

  35. 1992

  36. Korbelik, M., Krosl, G., Dougherty, G.J. and Chaplin, D.J.. Host cell infiltration into PDT-treated tumor SPIE 1645:124-130 (1992).

  37. 1991

  38. Korbelik, M., Krosl, G., Lam, S., Chaplin, D.J. and Palcic, B.. Microlocalization of Photofrin in neoplastic lesions SPIE 1426:172-179 (1991).

Books (and Chapters)

    2004

  1. Cecic, I., Stott, B., Sun., J. and Korbelik, M.:. Relevance of innate immunity recognition of altered self in the induction of host response associated with photodynamic therapy In: Recent Research Developments in Cancer, Vol. 5, S.G. Pandalai, Ed., Transworld Research Network, Trivandrum, India, 6:153-161 (2004).

  2. 2003

  3. Korbelik, M. and Cecic, I.: . Mechanisms of tumor destruction by photodynamic therapy. In Handbook of Photochemistry and Photobiology, Vol. 1, Chapter 2, H.S. Nalwa, Ed., American Scientific Publishers, Stevenson Ranch (CA), 2003 pp. 39-77. (2003).

  4. 1997

  5. Korbelik, M., Cecic, I., Shibuya, H.: . The role of nitric oxide in the response of cancerous lesions to photodynamic therapy Recent Research Developments in Photochemistry and Photobiology, S.G. Pandalai (ed.), Transworld Research Network, India, pp. 267-276 (1997).

  6. 1996

  7. Korbelik, M. and Krosl, G.. Photosensitizer distribution and photosensitized damage of tumor tissues. In: The Fundamental Bases of Phototherapy, H. Hönigsmann, G. Jori, and A.R. Young, Eds., OEMF spa, Milan, Italy, pp. 229-245. (1996).

  8. 1992

  9. Korbelik, M., Krosl, G., Dougherty, G.J., Chaplin, D.J.. Effect of SPG (Sonifilan) immunotherapy and PDT on murine tumors. In: Photodynamic Therapy and Biomedical Lasers. P. Spinelli, M. Dal Fante and R. Marchesini, Eds., Elsevier Science Publishers BV, Amsterdam, pp. 518-520. (1992).

  10. Krosl, G. and Korbelik, M.. Combining photodynamic therapy with immunotherapy: Will it work? In: Advances in Radiology and Oncology, T. Benulic, G. Sersa, V. Kovac, Eds., Radiologica Iugoslavica, Ljubljana, Slovenia, pp. 261-267. (1992).

  11. Krosl, G., Dougherty, G.J., Chaplin, D.J. and Korbelik, M.. PDT and tumour infiltrating immune cells. In: Photodynamic Therapy and Biomedical Lasers, P. Spinelli, M. DalFante and R. Marchesini, Eds., Elsevier Science Publishers BV, Amsterdam, pp. 513-517. (1992).

  12. 1989

  13. Boranic, M., poljak-Blazi, M. and Korbelik, M.. Experimental hematology and oncology In: Fundamentals of Hematology and Trasnfusiology, B. Labar, B. Jaksic & D. Grgicevic, Eds., Juemna press, Zagreb (1989).

  14. Korbelik, M., Skrk, J., Poljak-Blazi, M., Suhar, A., Turk, V. and Boranic, M.. The effects of human urinary kallikrein and aprotinin on nonmalignant and malignant cell growth. In: Adv. Exp. Biol. Med., K. Abe, H, Moriya and S. Fujii, Eds., Vol. 247B, pp. 675-680 (1989).

  15. 1986

  16. Korbelik, M., Skrk, J., Schauer, P., Suhar, A., Turk, V. and Likar, M.. The effect of intracellular proteinases on transformation of human lymphocytes. In: KININS IV, Part B (Advances in Experimental Biol. and Med., Vol. 198B), L.M. Greenbaum, and H.S. Margolins, Eds., Plenum Press, New York, pp. 113-120. (1986).

  17. Korbelik, M., Skrk, J., Suhar, A. and Filipic, B.. Interferons as stimulatory as well as inhibitory agents in cell proliferation and repair of radiation-induced potentially lethal damage. In: Yugoslav colloquium on interferon, B. Filipic, Ed., Ljubljana, pp. 61-66. (1986).

  18. Skrk, J., Korbelik, M., Suhar, A., Turk, V., Filipic, B., Kotnik, V. and Likar, M.. The effects of interferons on transformation of human lymphocytes. In: Yugoslav colloquium on interferon, B. Filipic, Ed., Ljubljana, pp. 63-67. (1986).

  19. Suhar, A., Korbelik, M., Skrk, J., Schauer, P., Petrovic, D. and Turk, V.. The role of cathepsins H and B, and inhibitors leupeptin and CPI in proliferative activities of nonmalignant and malignant cells in culture. In: Cysteine Proteinases and Their Inhibitors, V. Turk, Ed., Walter de Gruyter, Berlin, pp. 283-291. (1986).

  20. 1982

  21. Kopitar, M., Drobnic-Kosorok, M., Babnik, J., Brzin, J., Turk, V., Korbelik, M., Batista, U., Svetina, S., Skrk, J., Giraldi, T. and Sava, G.. Biochemical and biological characteristics of leucocyte proteinase inhibitors. In: Biochemistry and function of phagocytes (Advances in Experimental Medicine and Biology, Vol. 141), F. Rossi and P. Patriarca, Eds., Plenum Press, New York, pp. 233-245. (1982).

  22. Palcic, B., Korbelik, M. and Skarsgard, L.D.. Oxygen enhancement ratio and split dose recovery with pion beams. In: Pion and Heavy Ion Radiotherapy: Pre-clinical and Clinical Studies, L.D. Skarsgard, Ed., Elsevier Science Publishing Co. Inc., New York, pp. 211-218. (1982).

Presentations and Symposium Proceedings

    2007

  1. Korbelik, M. (co-chair and invited speaker) and Merchant, S.: . Role of heat shock protein 70 in systemic host response induced by tumor PDT. 11th World Congress of the International Photodynamic Association, Shanghai, March 28-31, (2007).

  2. Korbelik, M. (invited speaker): . Advances in the understanding of host response associated with tumor PDT. SPIE's BiOS 2006 International Symposium on Biomedical Optics, Conference: Biophotonics and Immune Responses (BO120), San Jose, California, January 20-25, (2007).

  3. Korbelik, M. (invited speaker): . Photodynamic therapy-generated cancer vaccine: therapeutic and mechanistic insights. 12th Congress of the European Society for Photobiology, Bath (UK), September 1-6, (2007).

  4. 2006

  5. Merchant, S., Stott, B., Sun, J. and Korbelik, M.: . Removal of dead tumor cells: expression of relevant genes. Annual Cancer Conference (BC Cancer Agency), Vancouver, November 23-25, (2006).

  6. Korbelik, M. (invited speaker and symposium co-chair), and Sun, J.: . Acute phase response induced following tumor treatment by photodynamic therapy: relevance for the therapy outcome. SPIE's BiOS 2006 International Symposium on Biomedical Optics, Conference: Biophotonics and Immune Responses (BO120), San Jose, California, January 21-26, (2006).

  7. Korbelik, M. (invited speaker and symposium co-chair): . Efferocytosis after tumor PDT and its impact. 33rd Meeting of the American Society for Photobiology, Puerto Rico, July 8-12, (2006).

  8. Korbelik, M. (invited speaker), Stott, B., and Merchant, S.: . Heat shock protein 70 as photodynamic therapy-induced danger signal eliciting Toll-like receptor-mediated host response. 5th International Workshop on the Molecular Biology of Stress Response, Concepcion, Chile, March 21-26, (2006).

  9. Korbelik, M. (invited speaker): . Cause and purpose of host response elicited by cancer treatment with light-based therapies, and its character. 20th Anniversary Laser Medicine Conference, Moscow, October 5-6, (2006).

  10. Korbelik, M., Merchant, S., Payne, P., and Stott, B.: . Expression of complement and pentraxin proteins associated with dead cell disposal following tumor-localized insult mediated by photodynamic therapy. 4th International Innate Immunity Conference, Corfu, Greece, June 4-9, (2006).

  11. 2005

  12. Korbelik, M.(symposium co-chair), Cecic, I., and Sun, J.: . Acute phase response elicited by tumor-localized photodynamic therapy. 10th Congress of the International Photodynamic Association, Munich, June 22-25, (2005).

  13. Korbelik, M., Stott, B., Cecic, I., and Sun, J.: . Photodynamic therapy of cancer elicits a local and systemic engagement of complement system including the upregulation of complement genes in treated tumors. 3rd Workshop on Complement Associated Diseases, Animal Models, and Therapeutics, Rhodes (Greece), June 5-10, (2005).

  14. Korbelik, M., and Dougherty, G.J.: . Complement activation approaches for use in conjunction with PDT for cancer treatment. SPIE's BiOS 2005 International Symposium on Biomedical Optics, Conference: Optical interactions with tissue and cells XVI (BO119), San Jose, California, January 22-27, (2005).

  15. Korbelik, M., and Sun, J.: . Cancer vaccine generated by photodynamic therapy: role of complement and heat shock proteins. Keystone Symposium: Basic Aspects of Tumor Immunology, Keystone, CO, March 19-24, (2005).

  16. 2004

  17. Cecic, I., Korbelik, M.: . PDT-induced tumor trauma significantly elevates serum levels of the acute phase reactant Serum amyloid P component (SAP) in mice. 32nd Annual Meeting of the American Society for Photobiology, Seattle, July 10-14, (2004).

  18. Chen, W.R., Sun, J., Liu, H., and Nordquist, R.E.: . Enhancement of glycated chitosan in laser treatment. SPIE BiOS 2004 International Symposium on Biomedical Optics, Conference: Laser Tissue Interaction XV: Photochemical, Photothermal, and Photomechanical (BO20), San Jose, California, January 24-29, (2004).

  19. Korbelik, M. (Invited Speaker): . PDT and Heat Shock Proteins. 14th International Congress on Photobiology, Jeju, Korea, June 10-14, (2004).

  20. Korbelik, M. (invited speaker): . Photodynamic therapy of cancer is associated with the activation of the complement system whose amplification can be exploited for therapeutic gain. International Conference on Laser Technologies in Medical Science and Practical Medicine, Moscow (Russia), October 7-8, (2004).

  21. Korbelik, M. (invited speaker): . The role of Toll-like receptors in photodynamic therapy-elicited host response. SPIE BiOS 2004 International Symposium on Biomedical Optics, Conference: Laser Tissue Interaction XV: Photochemical, Photothermal, and Photomechanical (BO20), San Jose, California, January 24-29, (2004).

  22. Korbelik, M., Cecic, I., Stott, B., Sun, J.: . Relevance of innate immunity recognition of altered self in the induction of host response associated with cancer therapies. Predictive Oncology and Intervention Strategies, ISPO 2004 Symposium, Nice, France, Feb. 7-10, (2004).

  23. Korbelik, M., Stott, B., Sun, J., and Cecic, I.: . Localized production of complement proteins in tumors treated by photodynamic therapy. XXth International Complement Workshop, Honolulu, Hawaii, June 13-18, (2004).

  24. Korbelik, M.: . Photodynamic therapy of cancer is associated with the activation of the complement system whose amplification can be exploited for therapeutic gain. Laser Medicine Conference, Moscow, Russia, Oct. 7-8, (2004).

  25. Stott, B., and Korbelik, M.: . Localized complement gene expression in tumors treated by photodynamic therapy. 32nd Annual Meeting of the American Society for Photobiology, Seattle, July 10-14, (2004).

  26. 2003

  27. Cecic, I. and Korbelik, M.:. The effect of complement activation during photodynamic light delivery in the treatment of solid tumors. 10th Congress of the European Society for Photobiology, Vienna (Austria), September 6-11, (2003).

  28. Cecic, I. and Korbelik, M.: . The impact of complement activation during photodynamic light delivery for treatment of solid tumors. 9th World Congress of the International Photodynamic Association, Miyazaki (Japan), May 20-23, (2003).

  29. Huang, Z., Lui, H., McLean, D.I., Korbelik, M., and Zeng, H.: . Combining near-infrared autofluorescence and raman spectroscopies for improving the noninvasive in vivo detection of malignant tumors. BC Cancer Agency Annual Cancer Conference, Vancouver, B.C., Abstract Book pg. 22, Abstract # 77, Nov. 28-29, (2003).

  30. Korbelik, M. (invited plenary speaker): . PDT-induced host defense mechanisms: inflammatory and immune responses. 9th World Congress of the International Photodynamic Association, Miyazaki (Japan), May 20-23, (2003).

  31. Korbelik, M. (invited speaker and symposium co-chair):. Role of innate immune system in tumor response to PDT. 31th Annual Meeting of the American Society for Photobiology, Baltimore, July 5-9, (2003).

  32. Korbelik, M. (invited speaker and symposium co-chair):. Activators of alternative complement pathway are highly efficient adjuvants to photodynamic therapy for cancer treatment. 10th Congress of the European Society for Photobiology, Vienna (Austria), September 6-11, (2003).

  33. Korbelik, M., (invited speaker) and Sun, J. Progress in the development of photodynamic therapy-generated cancer vaccines SPIEs BiOS 2003 International Symposium on Biomedical Optics, Conference: Laser Tissue Interaction XIV: Photochemical, Photothermal, and Photomechanical (BO20), San Jose, California, January 25-31 (2003).

  34. Korbelik, M., Cecic, I., Erdei, A., Sun, J.: . Role of complement in antitumor response elicited by photodynamic therapy. Second Complement Associated Diseases, Animal Models, and Therapeutics Workshop, Myconos (Greece), June 1-6 (2003).

  35. Korbelik, M., and Sun, J.:. Photodynamic therapy-generated vaccines prevent tumor recurrence after radiotherapy. 12th International Congress of Radiation Research, Brisbane (Australia), August 17-22, (2003).

  36. Korbelik, M.: . Host defense responses elicited by photodynamic therapy. Photomedicine Lecture Series, Wellman Laboratories of Photomedicine, Boston, October 21, (2003).

  37. 2002

  38. Cecic, I., and Korbelik, M. Photodynamic therapy enhances both effector and regulatory functions of the complement system in murine tumor models 30th Annual Meeting of the American Society for Photobiology, Quebec City, July 13-17 (2002).

  39. Korbelik, M. Generation of anti-cancer vaccine by photodynamic therapy 93rd Annual Meeting of the American Association for Cancer Research, San Francisco, April 6-10 (2002).

  40. Korbelik, M. (invited speaker and symposium organizer): . Addressing the problem of immunosuppression in photodynamic therapy of cancer. 30th Annual Meeting of the American Society for Photobiology, Quebec City, July 13-17, (2002).

  41. Korbelik, M. (invited speaker). Exploitation of photodynamic therapy-generated immune response in cancer immunotherapy 6th International Symposium on Predictive Oncology and Intervention Strategies, Pasteur Institute Paris, February 9-12 (2002).

  42. Korbelik, M. (invited speaker) and Cecic, I.: . Photodynamic therapy-induced complement activation BiOS 2002 International Symposium on Biomedical Optics, Conference: Optical Methods for Tumor Treatment and Detection: Mechanisms and Technologies in Photodynamic Therapy XI (BO26), San Jose, California, January 19-25, (2002).

  43. Korbelik, M. (invited speaker), Cecic, I., and Sluiter, W.: . PDT-induced nitrosative stress, BiOS 2002 International Symposium on Biomedical Optics, Conference: Laser Tissue Interaction XIII: Photochemical, Photothermal, and Photomechanical (BO18), San Jose, California, January 19-25, (2002).

  44. Korbelik, M. (symposium organizer and invited speaker). Addressing the problem of PDT-induced immunosuppression in cancer treatment 30th Annual Meeting of the American Society for Photobiology, Quebec City, July 13-17 (2002).

  45. Korbelik, M., Cecic, I. and Sun, J.: . Complement as a Key Mediator of the Antitumor Effect of Photodynamic Therapy. XIX International Complement Workshop. Palermo, Italy, September 22-26, (2002).

  46. Korbelik, M., and Sun, J. Development of photodynamic therapy-generated cancer vaccine First Tagernsee Conference on Immunotherapy of Solid Cancer, Tagernsee (Germany), July 3-5 (2002).

  47. Sluiter, W., Korbelik, M., Cecic, I., and de Wit, E. Neutrophil-mediated oxidative- and non-oxidative stress in tumors treated by photodynamic therapy 30th Annual Meeting of the American Society for Photobiology, Quebec City, July 13-17 (2002).

  48. Zeng, H., Korbelik, M., McLean, D.I., MacAulay, C.E., and Lui, H. Monitoring photoproduct and photobleaching by fluorescence spectroscopy for improving PDT dosimetry SPIEs BiOS 2002 International Symposium on Biomedical Optics, Conference: Optical Methods for Tumor Treatment and Detection: Mechanisms and Technologies in Photodynamic Therapy XI (BO26), San Jose, California, January 19-25 (2002).

  49. 2001

  50. Korbelik, M. (invited speaker), Cecic, I., and Sun, J.: . Relevance of PDT-induced inflammatory response for the outcome of photodynamic therapy. SPIEs International Biomedical Optics Symposium, San Jose, California, January 19-26 (2001).

  51. Korbelik, M. (invited speaker), Sun, J., Cecic, I., and Dougherty, G. The role of inflammatory cytokines in the response of solid cancers to photodynamic therapy SPIE International Biomedical Optics Symposium, San Jose, California, January 19-26 (2001).

  52. Korbelik, M. (invited speaker): . Photodynamic therapy as anti-cancer vaccine. 9th Congress of the European Society for Photobiology, Lillehammer, Norway, September 3-8 (2001).

  53. Korbelik, M. (invited speaker): . The role of host response in tumor ablation and cure following photodynamic therapy International Conference on Lasers and Information Technologies in Medicine in XXI Century, St. Petersburg, Russia, June 21-22, (2001).

  54. Korbelik, M., Cecic, I., and Sun, J. Complement as a key mediator of the antitumor effect of photodynamic therapy XIX International Complement Workshop, Palermo (Italy), September 22-26 (2001).

  55. Korbelik, M., Cecic, I., and Sun, J.: . Cancer treatment by photodynamic therapy engages complement in tumor tissue destruction Workshop on Complement Associated Diseases, Animal Models, and Therapeutics, Santorini, Greece, October 10-14 (2001).

  56. Korbelik, M., Sun, J., Dougherty, S.T., and Dougherty, G.J.: . Mechanism of IL-3 immunotherapy-mediated potentiation of tumor cures following photodynamic therapy 48th Annual Meeting of the Radiation Research Society, San Juan, Puerto Rico, April 21-25 (2001).

  57. Korbelik, M.:. Host defense responses elicited by photodynamic therapy. Photomedicine Lecture Series, Wellman Laboratories of Photomedicine, Boston, October 21, (2001).

  58. Zeng, H., Korbelik, M., McLean, D.I., MacAulay, C., Lui, H.: . Monitoring Photoproduct Formation and Photobleaching by Fluorescence Spectroscopy has the Potential to Improve PDT Dosimetry. The BC Cancer Agency Annual Cancer Conference, Vancouver, BC, Canada, November 23 and 24, (2001).

  59. 2000

  60. Cecic, I. and Korbelik, M.: . Tumor-localized treatment with photodynamic therapy triggers a systemic neutrophil response . 13th International Congress on Photobiology, San Francisco, CA, July 1-6 (2000).

  61. Korbelik M. (invited speaker): . The role of immune cells in PDT-induced death of cancer cells 13th International Congress on Photobiology, San Francisco, CA, April 1-5 (2000).

  62. Korbelik, M. (invited speaker) and Cecic I.: . Role of neutrophils in the destruction of PDT-targeted lesions SPIEs International Biomedical Optics Symposium, Conference on Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IX, San Jose, CA, January 22-28 (2000).

  63. Korbelik, M. (invited speaker), Cecic, I., Sun, J. and Dougherty, G.J.: . Neutrophil-directed immunotherapy combined with photodynamic therapy: prospects for effective control of solid cancers 5th World Congress on Advances in Oncology, Hersonissos, Crete, Greece, October 19-21 (2000).

  64. Korbelik, M. (invited speaker), Shibuya, H., Cecic, I. . Interleukin-3 immunotherapy potentiates the curative effect of photodynamic therapy in treatment of cancerous lesions 91st Annual Meeting of the American Association for Cancer Research, San Francisco, CA, April 1-5 (2000).

  65. Korbelik, M. (invited speaker): . Immunotherapy regimems for combination with photodynamic therapy aimed at eradication of solid cancers SPIEs International Biomedical Optics Symposium, Conference on Laser-Tissue Interaction XI: Photochemical, Photothermal, Photomechanical, San Jose, CA, January 22-28 (2000).

  66. 1999

  67. Korbelik, M. (invited speaker), Cecic, I., Sun, J., Chaplin, D.J.: . Examples of adjuvant treatment enhancing the antitumor effect of photodynamic therapy SPIEs International Biomedical Optics Symposium, Conference on Optical Methods for Tumor Treatment and Detection: Mechanisms and techniques in Photodynamic Therapy VIII, San Jose, CA, January 23-29 (1999).

  68. Korbelik, M. (invited speaker): . Antitumor immune reaction elicited by photodynamic therapy SPIEs International Biomedical Optics Symposium, Conference on Laser-Tissue Interaction X: Photochemical, Photothermal and Photomechanical, San Jose, CA, January 23-29 (1999).

  69. Korbelik, M. and Sun J.: . Photodynamic therapy combined with adoptive immunotherapy for eradication of solid cancers 11th Intl Congress on Radiation Research, Dublin, Ireland, July 23-28 (1999).

  70. Korbelik, M. and Sun, J.: . Vasculature targeting in photodynamic therapy-treated tumors by Combretastatin A4 8th Congress European Society for Photobiology, Granada, Spain, Sept. 3-8 (1999).

  71. Korbelik, M., Sun, J., Naraparaju, V.R., Yamamoto, N. Eradication of solid cancers by photodynamic therapy combined with dendritic cell-based adoptive immunotherapy 90th Annual Meeting of the American Association for Cancer Research, Philadelphia, PA, April 10-14 (1999).

  72. 1998

  73. Bissonnette, R., Zeng, H., Korbelik, M., McLean, D.I., Lui, H.: . Protoporphyrin IX fluorescence in psoriatic plaques and circulating blood cells after oral 5-ALA administration 7th Biennial Congress of the International Photodynamic Association, Nantes, France, July 7-9 (1998).

  74. Cecic, I., Korbelik, M. Nitric oxide-dependent contribution of neutrophils to anti-tumour effects of photodynamic therapy 7th Biennial Congress of the International Photodynamic Association, Nantes, France, July 7-9 (1998).

  75. Korbelik, M. (Invited speaker), Shibuya, H. and Cecic, I.: . Relevance of nitric oxide to the response of tumors to photodynamic therapy SPIEs International Biomedical Optics Symposium, Conference on Optical Methods for Tumor Treatment and Detection: Mechanisms and techniques in Photodynamic Therapy VII, San Jose, CA, January 22-25 (1998).

  76. Korbelik, M. (Invited speaker), and Sun, J.. Cancer treatment by photodynamic therapy combined with NK cell line based adoptive immunotherapy SPIEs International Biomedical Optics Symposium, Conference on Laser-Tissue Interaction IX, San Jose, CA, January 26-28 (1998).

  77. Korbelik, M. (invited speaker): . Anticancer activity of immune cells mediated by photodynamic therapy Gordon Research Conference on Lasers in Medicine and Biology, Meriden, New Hampshire, June 14-19 (1998).

  78. Korbelik, M., Cecic, I. . Synergistic effect of light-activated tumor-localized release of nitric oxide and photodynamic therapy 46tth Annual Meeting of the Radiation Research Society, Louisville, Kentucky, April 25-29 (1998).

  79. Korbelik, M., Cecic, I. and Shibuya, H.: . The role of nitric oxide in the response of solid cancers to photodynamic therapy 89th Annual Meeting of the American Association for Cancer Research, March 28-April 1, New Orleans, Louisiana, Abstract 4372 (1998).

  80. Korbelik, M., Sun, J.: . Response of tumors to photodynamic therapy combined with adoptive immunotherapy 7th Biennial congress of the International Photodynamic Association, Nantes, France, July 7-9 (1998).

  81. 1997

  82. 88. Korbelik, M., Naraparaju, V.R., and Yamamoto, N.: . Tumor response to radiotherapy and photodynamic therapy monitored by serum levels of α-N-Acetylgalactosaminidase. 45th Ann. Mtg. Radiation Research Society, Providence, Rhode Island, May 3-7 (Abstract Book p. 149) (1997).

  83. Berg, K., Bonnett, R., Jori, G., Kessel, D., and Korbelik, M. (invited round table panelists). Role of photosenstizer chemical structure and delivery system in photodynamic therapy 7th Congress of the European Society for Photobiology, Stresa, Italy, Sept. 8-13 (1997).

  84. Korbelik, M.. Combining PDT with BCG or mycobacterium cell wall immunotherapy for enhanced eradication of solid cancers. BiOS Europe '97, San Remo, Italy, Sept. 4-8 (Abstract 3191-30, Abstract Book p. 8) (1997).

  85. Korbelik, M. (invited speaker). Photodynamic therapy and tumor immunity. 7th Congress of the European Society for Photobiology, Stresa, Italy, Sept. 8-13 (Abstract Book p. 29) (1997).

  86. Korbelik, M., Shibuya, H. and Chaplin, D.J.. Role of nitric oxide in the regulation of tumor blood flow and in the response to cancer therapy International workshop : The tumor microenvironment: An important paradigm in cancer etiology and treatment, Martha's Vineyard, MA, April 28 - May 2 (1997).

  87. 1996

  88. Korbelik, M. . "How does PDT work?", Sixth Biennial Meeting of the International Photodynamic Therapy Association, Melbourne, Australia, Mar 10-14 (1996).

  89. Korbelik, M. (invited speaker). Photodynamic therapy and induction of tumour immunity 2nd. Symp. on Cancer Research, Sidney, B.C., May 24-26 (1996).

  90. Korbelik, M. (invited speaker). Host response in the antitumor effect of photodynamic therapy 12th Intl. Congress on Photobiology, Vienna, Austria, Sept. 1-6 (1996).

  91. Korbelik, M., Krosl, G., Krosl, J. and Dougherty, GJ.. "Modulation of tumor response to photodyanmic therapy in severe combined immundeficient (SCID) mice by adoptively transferred lymphoid cells", SPIE BiOS'96, San Jose, CA, Jan 27-Feb 2 (1996).

  92. Korbelik, M., Krosl, G., Krosl, J. and Dougherty, GJ. (invited speaker): . "Modulation of tumor response to photodynamic therapy in severe combined immundeficient (SCID) mice by adoptively transferred lymphoid cells", SPIE's International Biomedical Optics Symposium, Conference on Optical Methods for Tumor Treatment and Detection: Mechanisms and techniques in Photodynamic Therapy V, San Jose, CA, January 27-28, (1996).

  93. Korbelik, M., Krosl, G., Naraparaju, V.R. and Yamamoto, N.. Enzymatically generated macrophage activating factor (DBPMAF) as a potent adjuvant to photodynamic therapy of solid cancers Sixth Biennial Meeting of the International Photodynamic Therapy Association, Melbourne, Australia, March 10-14 (1996).

  94. Korbelik, M., Naraparaju, V.R. and Yamamoto, M.. Potentiation of photodynamic therapy of cancer by macrophage directed immunotherapy 24th Ann. Mtg. of the American Soc. for Photobiology, Atlanta, GA, June 15-20 (1996).

  95. Krobelik, M. (invited speaker) and Chaplin, D.J.. Antitumor effect of photodynamic therapy: The role of superoxide, hydrogen peroxide and nitric oxide 24th Ann. Mtg. of the American Soc. for Photobiology, Atlanta, GA, June 15-20 (1996).

  96. Krosl, G., Korbelik, M. and Krosl, J.. Role of T lymphocytes in the response of solid cancers to photodynamic therapy Sixth Biennial Meeting of the International Photodynamic Therapy Association, Melbourne, Australia, March 10-14 (1996).

  97. 1995

  98. Korbelik, M. (invited panelist). How does PDT work? Sixth Biennial Meeting of the International Photodynamic Therapy Association, Melbourne, Australia, March 10-14 (1995).

  99. Korbelik, M. (invited speaker), Krosl, G., Chaplin, D.J., Dougherty, G.J. and Yamamoto N.. Direct and indirect antitumor effects in photodynamic therapy Sixth Congress of the European Society for Photobiology, Cambridge, UK, September 3-8 (1995).

  100. Korbelik, M., Krosl, G., Naraparaju, V. R., Yamamoto, N.. The effect of enzymatically generated macrophage activating factor (GcMAF) on the tumor response to photodynamic therapy (PDT) 23rd Annual Meeting of the Amercian Society for Photobiology, Washington, DC, June 17-22 (1995).

  101. 1994

  102. Korbelik, M. and Krosl, G.. Photodynamic therapy but not x-ray treatment of tumor cells potentiates their susceptability to macrophage-mediated cytolysis , Rad. Res. 42nd Ann Mtg., Nashville, Tennessee, April 29-May 4 (1994).

  103. 1993

  104. Korbelik, M. and Krosl, G.. Distribution of photosensitizers between tumor cells and tumor infiltrating host cells Intl Symp Biomedical Optics Europe'93, Budapest, Hungary, September 1-5 (1993).

  105. Korbelik, M., Krosl, G. and Chaplin, D.J.. Nicotinamide and carbogen breathing enhance the effect of photodynamic therapy of solid tumors 41st Ann. Mtg. Radiation Research Society, Dallas, Texas, March 20-25 (1993).

  106. Korbelik, M., Krosl, G. and Dougherty, G.J.. PDT elicited tumoricidal activity of tumor associated macrophages 21 Ann Mtg Amer Soc Photobiol, Chicago, Illinois, June 26-30 (1993).

  107. Lam, S., MacAulay, C., Korbelik, M. and Palcic, B.. Fluorescence imaging of pre-malignant and malignant tissue SPIE, Biomedical Optics'93, Los Angeles, Jan 16-22 (1993).

  108. Skrk, J., Osmak, M., Petrovic, D., Ferle-Vidovic A., Suhar, A., Svetic, B., Gabrijelcic, D., Vrhovec, I., Turk, V. and Korbelik, M.. Intracellular proteinase levels and activity in irradiated cells Workshop: Molecular, Cellular and Genetic Basis of Radiosensitivity at Low Doses: A Case of Induced Repair?, Chateau Whistler, British Columbia, May 9-13 (1993).

  109. 1992

  110. Korbelik, M., Krosl, G. and Chaplin, D.J.. Host cell infiltration into PDT-treated tumor SPIE Biomedical Optics'92, Los Angeles, California, January 19-24 (1992).

  111. Korbelik, M., Krosl, G., Adomat, H. and Skov, K., . "Use of HL-60 human promyelocytic leukemia cell line for studies in photodynamic therapy", Amer. Soc. Photobiol., Marco Island, FL, June 20-24 (1992).

  112. 1991

  113. Korbelik, M.. Role of serum in cellular delivery and retention of photosensitizers: Human vs mouse and bovine sera. 4th Cong. Eur. Soc. Photobiol., Amsterdam, The Netherlands, September 1-6 (1991).

  114. Korbelik, M., Krosl, G. and Chaplin, D.J.. Can PDT be potentiated by immunotherapy? Intl. Conf. on Photodynamic Therapy and Laser Medicine, Beijing, China, October 15-17, Abstract L32, p. 33 (1991).

  115. Krosl, G., Korbelik, M. and Palcic, B.. Effects of Sonifilan on tumor response to photodyanmic therapy The University of British Columbia Health Science Student Research Forum, October 10 (1991).

  116. Skov, K., Walter, P., MacPhail, S., Korbelik, M. and Adomat, H.. Further studies on the interaction in hypoxic cells between cisplatin and x-rays at clinically relevant doses. 6th Intl. Symp. on Platinum and Other Metal Complexes in Cancer Therapy, San Diego, CA, January (1991).

  117. 1990

  118. Hung, J., Korbelik, M., Lam, S., Chaplin, D., Krosl, G. and Palcic, B.. Localization of polyhematoporphyrin derivative in tumors 18th Ann. Mtg. Amer. Soc. for Photobiology, Vancouver, B.C., June 16-20 (1990).

  119. Korbelik, M., Chaplin, D.J., Krosl, G., Lam, S., Durand, R.E., Olive, P.L. and Palcic, B.. Tumor associated macrophages: Role in Photofrin II tumor localization 3rd Biennial Mtg. Intl. Photodynamic Assoc. Buffalo, N.Y., July 17-21, Abstract XIV/4 (1990).

  120. Korbelik, M., Hung, J., Lam, S. and Palcic, B.. Cellular delivery and retention of Photofrin II: The role of interaction with human serum proteins 18th Ann. Mtg. Amer. Soc. for Photobiology, Vancouver, B.C., June 16-20 (1990).

  121. Korbelik, M., Hung, J., Lam, S. and Palcic, B.. Cellular delivery/retention of Photofrin II: The role of plasma proteins 3rd Western Radiobiology Workshop, Penticton, B.C., February 12-19 (1990).

  122. Korbelik, M., Hung, J., Lam, S. and Palcic, B.. The role of plasma constituents in cellular uptake and retention of Photofrin II Radiat. Res. Soc. 38th Ann. Sci. Mtg., New Orleans, Louisiana, April 7-12, p. 202 (1990).

  123. Krosl, G., Korbelik, M., Chaplin, D., Lam, S. and Palcic, B.. The role of macrophages in tumor-localizing properties of Photofrin II 18th Ann. Mtg. Amer. Soc. for Photobiology, Vancouver, B.C., June 16-20 (1990).

  124. 1989

  125. Korbelik, M., Palcic, B. and Skov, K.A.: . Cisplatin enhancement of response to low radiation doses in hypoxia. Radiat. Res., Seattle, Washington, March 18-22, p. 152, (1989).

  126. Osmak, M., Korbelik, M., Arezina, R., Skrk, J., Suhar, A. and Turk, V.. Soybean trypsin inhibitor protects Chinese hamster cells from ionizing radiation 3rd Intl. Conf. on Anticarcinogenesis and Radiation Protection, Dubrovnik, Croatia, October 16-21 (1989).

  127. Skov, K., MacPhail, S., Korbelik, M. and Palcic, B.. Metal complexes - Interaction with low radiation doses DNA Targetted Hypoxic Cytotoxins and Radiosensitizers Workshop, Vancouver, B.C., March 16-18 (1989).

  128. 1988

  129. Korbelik, M., Hung, J., Lam, S. and Palcic, B.: . In vitro tumor model for estimation of HpD in small foci for fluorescence endoscopic apparatus measurements. Brit. Med. Laser Assoc., Intl. Conf. Photodynamic Therapy and Medical Laser Appl., London, England, July 19-21, p. 117, (1988).

  130. Skov, K.A., Korbelik, M. and Palcic, B.. The interaction of Trans-DDP [Diamminedichloroplatinum(II)] with low doses of radiation in mammalian cells VI Intl. Mtg. on Chemical Modifiers of Cancer Treatment, Paris, March 21-25 (1988).

  131. Skrk, J., Korbelik, M., Suhar, A., Filipic, B., Turk V. and Likar M.. The role of interferons in cell proliferative activities Intl. Symp. on Human Viral Diseases, Ljubljana, Slovenia, May 27-28 (1988).

  132. Takahashi, H., Thurston, G., Korbelik, M., Palcic, B., Damji, K. and Rootman, J.. Assessment of anti-proliferative and anti-motility drugs for treatment of fibroblast proliferation Digital Imaging Technology for Oncology, Terry Fox Workshop, Vancouver, B.C., October 19-22, p. 24 (1988).

  133. Takahashi, H., Thurston, G., Korbelik, M., Palcic, B., Damji, K. and Rootman, J.. Assessment of anti-proliferative and anti-motility drugs for the treatment of ocular fibroblast proliferation 8th International Congress on Eye Research, San Francisco, California, September (1988).

  134. 1987

  135. Korbelik, M., Skrk, J., Poljak-Blazi, M., Suhar, A., Turk, V. and Boranic, M.. The effects of human urinary kallikrein and aprotinin on nonmalignant and malignant cell growth KININ'87 International Congress, Tokyo, Japan, November (1987).

  136. Korbelik, M., Suhar, A., Osmak, M., Skrk, J. and Turk, V.. Dynamics of postirradiation intracellular proteinases profiles in proliferating and nonproliferating cells Eighteenth Meeting of Federation of European Biochemical Societies (FEBS), Ljubljana, Slovenia, June (1987).

  137. Osmak, M., Korbelik, M., Suhar, A., Skrk, J. and Turk, V.. The influence of cathepsin B and leupeptin on repair of potentially lethal damage induced by radiation Eighteenth Meeting of Federation of European Biochemical Societies (FEBS), Ljubljana, Slovenia, June (1987).

  138. Skrk, J., Suhar, A., Batista, U., Korbelik, M., Fras, P. and Turk, V.. Biological and biochemical characterization of malignant ascites from patients with ovarian cancer 8th Regional Meeting of Biochemists, Biophysicists and Biotechnologists, Graz, Austria, October 29-31 (1987).

  139. Skrk, J., Suhar, A., Fras, P., Batista, U., Korbelik M. and Turk V.. Biological and biochemical characterization of malign ascites from ovary cancer patients 7th Congress of Cancerologists of Yugoslavia, Novi Sad Yugoslavia, October 14-17 (1987).

  140. 1986

  141. Korbelik, M., Skrk, J., Suhar, A. and Filipic, B.. Interferons as stimulatory as well as inhibitory agents in cell proliferation and repair of radiation-induced potentially lethal damage Yugoslav Colloquium on Interferon, Ljubljana, Slovenia, May (1986).

  142. Korbelik, M., Skrk, J., Suhar, A. and Turk, V.. The role of intracellular proteinases in repair of potentially lethal radiolesions Molecular Biology of DNA repair, Manchester, England, April (1986).

  143. Poljak-Blazi, M., Boranic, M. and Korbelik, M.. Clonal cultures of leukemic cells Fifth Congress of Hematologists and Transfusiologists of Yugoslavia, Maribor, Slovenia, September (1986).

  144. Skrk, J., Korbelik, M., Suhar, A., Filipic, B., Kotnik, V., Turk, V. and Likar, M.. The effects of interferons on transformation of human lymphocytes Yugoslav Colloquium on Interferon, Ljubljana, Slovenia, May (1986).

  145. 1985

  146. Korbelik, M., Skrk, J., Suhar, A., Schauer, P. and Turk, V.. The role of intra- and extra-cellular proteinases, their inhibitors, interferons and hormones in proliferative activities of mammalian cells in culture Sixteenth Yugoslav Symposium on Biophysics, Kranjska Gora, Slovenia, October (1985).

  147. Korbelik, M., Skrk, J., Suhar, A., Schauer, P., Petrovic, D. and Turk, V.. The effects of proteinases, their inhibitors, and interferons on repair of radiation-induced potentially lethal damage Nineteenth Annual Meeting of European Society for Radiation Biology, Prague, Czechoslovakia, August (1985).

  148. Korbelik, M., Suhar, A., Skrk, J., Schauer, P., Petrovic, D. and Turk, V.. The effects of proteinases on repair of potentially lethal damage induced by radiation Thirteenth Yugoslav Symposium on Radiation Protection, Pula, Croatia, June (1985).

  149. Suhar, A., Korbelik, M., Skrk, J., Schauer, P., Petrovic, D. and Turk, V.. The role of cathepsins H and B, and inhibitors leupeptin and CPI in proliferative activities of nonmalignant and malignant cells in culture International Symposium on Cysteine Proteinases and Their Inhibitors, Portoroz, Slovenia, September (1985).

  150. 1984

  151. Korbelik, M., Schauer, P., Suhar, A., Skrk, J., Petrovic, D. and Turk, V.. The effect of intracellular proteinases and their specific inhibitors on repair of radiation damage Eighteenth Annual Meeting of European Society for Radiation Biology, Zurich, Switzerland, September (1984).

  152. Korbelik, M., Schauer, P., Suhar, A., Skrk, J., Turk, V. and Likar, M.. The role of intracellular proteinases in eukaryotic cell mitotic cycle Meeting of Biophysicists of Slovenia, Ljubljana, Slovenia, April (1984).

  153. Korbelik, M., Skrk, J., Schauer, P., Suhar, A., Turk, V. and Likar, M.. The effects of intracellular proteinases and their inhibitors on transformation of human lymphocytes in vitro Second Congress of Biologists of Croatia, Zadar, Croatia, October (1984).

  154. Schauer, P., Korbelik, M., Suhar, A., Skrk, J., Turk, V. and Likar, M.. The role of intracellular proteinases in the cell cycle of eukaryotes Eighth International Biophysics Congress, Bristol, U.K., July (1984).

  155. Skrk, J., Korbelik, M., Schauer, P., Suhar, A., Turk, V. and Likar, M.. The effect of intracellular proteinases on transformation of human lymphocytes KININ'84 International Congress, Savannah, Georgia, October (1984).

  156. 1983

  157. Batista, U., Korbelik, M., Sever, J. and Skrk, J.. Comparison of some characteristics of malignant ascites maintained with clinical symptoms of the same patients Sixth Congress of Yugoslav Cancerologists, Skopje, Macedonia, October (1983).

  158. Palcic, B., Korbelik, M., Skarsgard, L.D. and Trotter, M.. Reduced OER for fractionated irradiation of exponentially growing and plateau phase mammalian cells 11th L.H. Gray Conference, Glasgow, Scotland, July 18-22 (1983).

  159. Schauer, P., Korbelik, M., Suhar, A., Skrk, J., Turk, V. and Likar, V.. The influence of intracellular proteinases on cell proliferation Fourteenth Yugoslav Symposium on Biophysics, Opatija, Croatia, September (1983).

  160. 1981

  161. Korbelik, M.. Low dose fractionation studies using mammalian cells in vitro Northwest Radiobiology Workshop, Banff, December (1981).

  162. Korbelik, M., Palcic, B., Skov, K. and Skarsgard, L.D.. Misonidazole and potentially lethal damage Conference on Chemical Modification: Radiation and Cytotoxic Drugs, Key Biscayne, Florida, September (1981).

  163. Palcic, B., Korbelik, M. and Skarsgard, L.D.. Oxygen enhancement ratio and split dose recovery with pion beams International Workshop on Pion and Heavy Ion Radiotherapy, Vancouver, B.C., Canada, July (1981).

  164. Skov, K., Korbelik, M., Palcic, B. and Skarsgard, L.D.. Energy and misonidazole toxicity: The effects of 5-thio-D-glucose Conference on Chemical Modification: Radiation and Cytotoxic Drugs, Key Biscayne, Florida, September (1981).

  165. 1980

  166. Palcic, B., Josephy, P.D., Korbelik, M. and Skarsgard, L.D.. Metabolism and cytotoxicity studies Canadian Association of Radiologists, 43rd Annual Meeting, Montreal, Canada, May 11-15, p. 150 (1980).

  167. 1979

  168. Crnivec, R. and Korbelik, M.. Differential cytotoxicity of nitroaromatic drugs: New perspectives in combined chemotherapy Fifth Congress of Yugoslav Cancerologists, Ljubljana, Slovenia, October (1979).

  169. Korbelik, M.. Interaction of nitroaromatic molecules reductive metabolism products with glycolysis in mammalian cells Sixth Meeting of Chemists of Croatia, Zagreb, Croatia, February (1979).

  170. Korbelik, M. and Horvat, D.. The mutagenicity of nitroaromatic drugs Effect of metronidazole after incubation in hypoxia in vitro. Ninth Annual Meeting of European Environmental Mutagen Society, Tucepi, Croatia, September (1979).

  171. Korbelik, M. and Sentjurc, M.. Epr study of mammalian cells transformation induced by some chemotherapeutic drugs Tenth Yugoslav Symposium on Biophysics, Radenci, Slovenia, October (1979).

  172. Korbelik, M. and Skrk, J.. Monitoring of some parameters of transformation process induced by nitroimidazole derivatives Fifth Congress of Yugoslav Cancerologists, Ljubljana, Slovenia, October (1979).

  173. 1977

  174. Korbelik, M.. Differential cytotoxicity and metabolic processes in mammalian cells Eighth L.H. Gray Conference: Hypoxic Cell Sensitizers, Cambridge, England, September (1977).

  175. Otto, M. and Korbelik, M.. Inhibitory effect of some nitroaromatic compounds on phosphofructokinase Yugoslav Symposium on Enzymes, Zagreb, Croatia, February (1977).

  176. 1976

  177. Korbelik, M. and Crnivec, R.. Differential toxicity of some nitroimidazoles used in pharmacology Seventh Yugoslav Symposium on Biophysics, Bled, Slovenia, November (1976).

  178. Pavlic, M., Korbelik, M. and Svetina, S.. Linkage between changing concentrations of 2,3-diphosphoglycerate and potassium in erythrocytes incubated with inosine and piruvate First Yugoslav Biochemistry Congress, Portoroz, Slovenia, September (1976).

  179. 1972

  180. Han, A. and Korbelik, M.. Ultraviolet light induced DNA-to-protein crosslinking in mammalian cells Ninth Annual Meeting of European Society for Radiation Biology, Rome, Italy, September (1972).

  181. 1971

  182. Korbelik, M. and Prostenik, M.. Phospholipase A in toxins of horned viper (vipera ammodytes ammodytes) and common adder (vipera berus) Second Yugoslav Symposium on Chemistry and Technology of Macromoleculs, Zagreb, Croatia, February (1971).

Abstracts

    2004

  1. Cecic, I., Korbelik, M.: . PDT-induced tumor trauma significantly elevates serum levels of the acute phase reactant serum amyloid P-component. 32nd Annual Meeting of the American Society for Photobiology, Seattle, WA., Abstract Book pg. 43, #137, July 10-14, (2004).

  2. Korbelik, M., Cecic, I., Stott, B., Sun, J.: . Relevance of innate immunity recognition of altered self in the induction of host response associated with cancer therapies. Cancer Detect. Prev., 28 (Suppl.): S168-S169, (2004).

  3. Korbelik, M., Stott, B., Sun, J., and Cecic, I.: . Localized production of complement proteins in tumors treated by photodynamic therapy. Mol. Immunol., 41: 260, (2004).

  4. Korbelik, M.: . PDT-induced host response and its manipulation for the therapeutic gain. 32nd Annual Meeting of the American Society for Photobiology, Seattle, WA., Abstract Book pg. 14, #43, July 10-14, (2004).

  5. Korbelik, M.: . Photodynamic therapy of cancer is associated with the activation of the complement system whose amplification can be exploited for therapeutic gain. Laser Medicine (Moscow), 8(3): 202, (2004).

  6. Stott, B., Korbelik, M.: . Localized complement gene expression in tumours treated by photodynamic therapy. 32nd Annual Meeting of the American Society for Photobiology, Seattle, WA., Abstract Book pg. 29, # 92, July 10-14, (2004).

  7. 2003

  8. Huang, Z., Lui, H., McLean, D.I., Korbelik, M., and Zeng, H.: . Combining near-infrared autofluorescence and raman spectroscopies for improving the noninvasive in vivo detection of malignant tumors. BC Cancer Agency Annual Cancer Conference, Vancouver, B.C., Abstract Book pg. 22, Abstract # 77, Nov. 28-29, (2003).

  9. 2002

  10. Korbelik, M. Exploitation of photodynamic therapy-generated immune response in cancer immunotherapy Cancer Detection and Prevention, 26 (Suppl.):S201 (2002).

  11. Korbelik, M. Generation of anti-cancer vaccine by photodynamic therapy Am. Assoc. Cancer Res. Proc., 43:979 (2002).

  12. Korbelik, M., Cecic, I., and Sun, J.: . Complement as a key mediator of the antitumor effect of photodynamic therapy. Int. Immunopharmacol., 2(9): 1318, (2002).

  13. 2001

  14. Cecic, I., and Korbelik, M.: . The role of complement in the response of tumors to photodynamic therapy IPA 8th World Congress of Photodynamic Medicine, Vancouver, B.C., June 5-9, Abstract Book, pg. 53 (2001).

  15. Korbelik, M. (invited speaker/co-chair), . Engagement of PDT-induced host immune defence mechanisms in the eradication of cancerous lesions IPA 8th World Congress of Photodynamic Medicine, Vancouver, B.C., June 5-9, Abstract Book, pg. 46 (2001).

  16. Sun, J., and Korbelik, M.:. Adoptive immunotherapy with genetically altered natural killer cell line increases the cure rate of PDT-treated tumors. IPA 8th World Congress of Photodynamic Medicine, Vancouver, B.C., June 5-9, Abstract Book, pg. 46 (2001).

  17. Zeng, H., Korbelik, M., Mclean, D., MacAulay, C., and Lui, H.: . Monitoring Photoproduct Formation and Photobleaching by Fluorescence Spectroscopy Improves PDT Dosimetry IPA 8th World Congress of Photodynamic Medicine, Vancouver, B.C., June 5-9, Abstract Book, pg. 40 (2001).

  18. 2000

  19. Korbelik, M., Cecic, I., Sun, J. and Dougherty, G.J.: . Neutrophil-directed immunotherapy combined with photodynamic therapy: Prospects for effective control of solid cancers. Internationl Journal of Molecular Medicine, 6 (Suppl. 1):S13, (2000).

  20. Korbelik, M., Dougherty, G.J.: . Interleukin-3 immunotherapy potentiates the curative effect of photodynamic therapy in treatment of cancerous lesions 91st Ann. Am. Assoc. Cancer Res. Proc., 41: 190 (2000).

  21. 1999

  22. Korbelik, M. (invited speaker), Cecic, I., Sun, J., Chaplin D.J.: . Examples of adjuvant treatment enhancing the antitumor effect of photodynamic therapy. SPIE 3592:65-72, (1999).

  23. Korbelik, M. (invited speaker): . Antitumor immune reaction elicited by photodynamic therapy. SPIE 3601:68-74, (1999).

  24. Korbelik, M., Sun, J., Naraparaju, V.R., Yamamoto, N.: . Eradication of solid cancers by photodynamic therapy combined with dendritic cell-based adoptive immunotherapy. 90th Ann. Am. Assoc. Cancer Res. Proc., 40: 86 (1999).

  25. 1998

  26. Cecic, I. and Korbelik, M.: . Nitric oxide dependent contribution of neutrophils to antitumor effects of photodynamic therapy 7th Congress of the Int. Photodynamic Assc, July 7-9, Nantes, France, Abstract RC4, p. 52 (1998).

  27. Korbelik, M.. The role of nitric oxide in the response of solid cancers to photodynamic therapy American Association for Cancer Research, March 28-April 1,New Orleans, Louisiana, Abstract 4372 (1998).

  28. Korbelik, M. (invited speaker). Anticancer activity of immune cells mediated by photodynamic therapy Gordon Research Conference on Lasers in Medicine and Biology, Meriden, New Hamphire, June 14-19 (1998).

  29. Korbelik, M. (invited speaker), Shibuya, H., Cecic, I.. Relevance of nitric oxide to the response of tumors to photodynamic therapy SPIE 3247-20:33 (1998).

  30. Korbelik, M., Sun, J.. Cancer treatment by photodynamic therapy combined with NK cell line based adoptive immunotherapy SPIE 3254-01:97 (1998).

  31. Korbelik, M., and Sun, J.: . Response of tumors to photodynamic therapy combined with adoptive immunotherapy 7th Congress of the Int. Photodynamic Assc, July 7-9, Nantes, France, Abstract RC3, p. 52 (1998).

  32. 1997

  33. Korbelik, M. (invited speaker). The role of nitric oxide in the response of solid tumors to photodynamic therapy Photochem. Photobiol. Suppl. 65:55S (1997).

  34. Korbelik, M. (invited speaker). Photodynamic therapy combined with adoptive immunotherapy for effective eradication of solid cancers Photochem. Photobiol. Suppl. 65:56S (1997).

  35. Korbelik, M., Naraparaju, V.R., H. Shibuya and Yamamoto, N.: . Tumor response to photodynamic therapy monitored by the cancer specific enzyme alpha-N-acetylgalactosaminidase. Photochem. Photobiol. Suppl. 65:47S (1997).

  36. 1996

  37. Korbelik, M. (invited speaker), and Chaplin, D.J.. Antitumor effect of photodynamic therapy: the role of superoxide, hydrogen peroxide and nitric oxide Photochem. Photobiol. 63:40S (1996).

  38. Korbelik, M., Naraparaju, V.R., and Yamamoto, N.. Potentiation of photodynamic therapy of cancer by macrophage directed immunotherapy Photochem. Photobiol. 63:65S (1996).

  39. 1995

  40. Korbelik, M. and Krosl, G., . "Distinctive role of activated tumor associated macrophages in photosensitizer accumulation", SPIE 2392-24:128, (1995).

  41. Korbelik, M., Krosl, G., Naraparaju VR, Yamamoto N.. The effect of enzymatically generated macrophage activating factor (GcMAF) on the tumor response to photodynamic therapy Photochem. Photobiol. Suppl. 61:97S (1995).

  42. 1994

  43. Korbelik, M. and Krosl, G., . "Tumor associated macrophages (not tumor cells) are the determinants of photosensitizer tumor localization", Proc. 5th Intl. Photodynamic Assoc. Biennial Mtg, Amelia Island, Florida, Sept. 21-24, Abstract 144:90 (1994).

  44. Krosl, G., Korbelik, M., Krosl, J. and Dougherty, G.J., . "Potentiation of photodynamic therapy by granulocyte-macrophage colony stimulating factor immunotherapy", 5th Int'l. Photodynamic Assoc. Biennial Mtg , Amelia Island, Florida, Sept. 21-24, Abstract 145:91 (1994).

  45. 1993

  46. Korbelik, M. and Krosl, G.. Distance from the blood vessel as a determinant of cellular photosensitizer levels within the tumor Photochem. Photobiol. Suppl. 59:76S (1993).

  47. Korbelik, M. and Matisic, J., . "Electron microscopy study of tumor destruction by photodynamic therapy", SPIE Biomedical Optics'93, Los Angeles, January 16-22, Abstract 1881-43 (1993).

  48. Korbelik, M., Krosl, G., and Dougherty, G.J.. PDT elicited tumoricidal activity of tumor associated macrophages Photochem. Photobiol. Suppl. 57:91S (1993).

  49. 1992

  50. Dougherty, G.J., Thacker, J.D., McBride, W.H., Krosl, G. and Korbelik, M.. Effect of immunization with genetically-modified tumor cells on tumor recurrence following photodynamic therapy Lasers Med. Sci. 7:226 (1992).

  51. Korbelik, M., Krosl, G., Adomat, H. and Skov, K.A.. Use of HL60 human promyelocytic leukemia cell line for studies in photodynamic therapy Photochem. Photobiol. Suppl. 55: 54S-55S (1992).

  52. Korbelik, M., Krosl, G., Dougherty, G.J. and Chaplin, D.J.. Effect of SPG (Sonifilan) immunotherapy and PDT on murine tumor Lasers Med. Sci. 7:227 (1992).

  53. Krosl, G., Dougherty, G.J., Chaplin, D.J. and Korbelik, M.. PDT and tumor infiltrating immune cells Lasers Med. Sci. 7:227 (1992).

  54. 1991

  55. Korbelik, M., Krosl, G. and Chaplin, D.J.. The effect of immunomodulators on Photofrin levels in solid tumors Photochem. Photobiol. Suppl. 53:102S (1991).

  56. Korbelik, M., Krosl, G. and Chaplin, D.J.: . Can PDT be potentiated by immunotherapy? Intl. Conf. on Photodynamic Therapy and Laser Medicine, Beijing, China, October 15-17, Abstract L32, p. 33, (1991).

  57. Krosl, G., Grulkey, W., Lam, S., Chaplin, D.J. and Korbelik, M.. Microlocalization of Photofrin and other photosensitizers in different types of solid tumors Photochem. Photobiol. Suppl. 53:118S (1991).

  58. 1990

  59. Hung, J., Korbelik, M., Lam, S., Chaplin, D., Simon, G.T., and Palcic, B.. Localization of polyhematoporphyrin derivative in tumors Photochem. Photobiol. Suppl. 51:13S (1990).

  60. Korbelik, M., Hung, J., Lam, S., and Palcic, B.. Cellular delivery and retention of photofrin II: the role of interaction with human serum proteins Photochem. Photobiol. Suppl. 51:82S (1990).

  61. Krosl, G., Korbelik, M., Chaplin, D., lam, S., and Palcic, B.. The role of macrophages in tumor-localizing properties of photofrin II Photochem. Photobiol. Suppl. 51:13S (1990).

  62. 1989

  63. Hung, J., Korbelik, M., Lam, S. and Palcic, B.. The effect of low density lipoproteins on uptake and clearance of Photofrin II from cultured cells Photochem. Photobiol. 49:745 (1989).

  64. Korbelik, M., Hung, J., Lam, S. and Palcic, B.. The effect of low density lipoprotein on uptake of Photofrin II in cultured cells 37th Annual Meeting of Radiation Research Society, Seattle, Washington, March 18-22, p. 112 (1989).

  65. Korbelik, M., Palcic, B. and Skov, K.A.. Cisplatin enhancement of response to low radiation doses in hypoxia Radiat. Res., Seattle, Washington, March 18-22, p. 152 (1989).

  66. Lam, S., Palcic, B., McLean, D., Fengler, J., Hung, J., Korbelik, M. and Profio, A.E.. Localization of early lung cancer by fluorescence bronchoscopy without skin photosensitivity 6th World Congress for Bronchology, Tokyo, Japan, October 18-22, Abstract 106 (1989).

  67. 1988

  68. Korbelik, M., Hung, J., Lam, S. and Palcic, B.. In vitro tumor model for estimation of HpD in small foci for fluorescence endoscopic apparatus measurements Brit. Med. Laser Assoc., Intl. Conf. Photodynamic Therapy & Medical Laser Appl., London, England, July 19-21, p. 117 (1988).

  69. Korbelik, M., Skov, K.A. and Palcic, B. (Sponsor P.K.L. Chan). Modification of low dose radiation response by platinum drugs Radiat. Res., Philadelphia, PA, April 16-21, p. 157 (Fg-6) (1988).

  70. Korbelik, M., Skrk, J., Suhar, A. and Turk, V.. Modification of repair of potentially lethal radiolesions by intra- and extra-cellular proteinases and their inhibitors Radiat. Res., Philadelphia, PA, April 16-21, p. 68 (Cp-5) (1988).

  71. Palcic, B. and Korbelik, M.. OER of acutely hypoxic cells irradiated to small fractionated doses of x-rays Radiat. Res., Philadelphia, PA, April 16-21, p. 13 (Dq-10) (1988).

  72. 1987

  73. Korbelik, M., Osmak, M., Arezina, R., Skrk, J., Suhar, A. and Turk, V.. Radioprotective effects of inhibitors of neutral proteinases Intl. J. Radiat. Biol. 51:938 (1987).

  74. Osmak, M., Korbelik, M., Rac, M., Petrovic, D., Suhar, A., Skrk, J. and Turk, V.. The influence of cathepsin B and leupeptin on recovery from potentially lethal damage Int. J. Radiat. Biol. 51:757 (1987).

  75. 1986

  76. Korbelik, M., Skrk, J., Suhar, A., Schauer, P., Petrovic, D. and Turk, V.. The role of intrinsic, intracellular and extracellular factors on repair of potentially lethal damage: A possible mechanism for variations in radiosensitivity in vivo Intl. J. Radiat. Biol. 49:701 (1986).

  77. 1982

  78. Korbelik, M., Palcic, B. and Skarsgard, L.. Misonidazole-induced potentially lethal damage and its role in the preincubation effect Radiat. Res. 91:408 (1982).

  79. Korbelik, M., Palcic, B. and Skarsgard, L.D.. Reduced enhancement ratios of oxygen and misonidazole with fractionated irradiation Radiat. Res. 91:331 (1982).

  80. 1981

  81. Korbelik, M., Palcic, B. and Skarsgard, L.D.. Misonidazole cytotoxicity and its interaction with radiation Radiat. Res. 87:434 (1981).

  82. Skarsgard, L.D., Palcic, B., Korbelik, M. and Lam, G.K.Y.. Cellular studies of RBE and split-dose recovery using the TRIUMF biomedical negative pion beam Radiat. Res. 87:407 (1981).

  83. 1980

  84. Korbelik, M., Palcic, B. and Skarsgard, L.D.. Misonidazole cytotoxicity of irradiated hypoxic mammalian cells Radiat. Res. 82:481 (1980).

Publications

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