Kim Lonergan, Ph.D.

 klonergan@bccrc.ca

• Research Associate

Department:	Cancer Genetics (@ the BCCRC since 1998)
Research Role:	Research Associate
Education:	Ph.D., Biochemistry, Dalhouisie University, 1993 PDF, Dana Farber Cancer Inst., Harvard Medical School
Birthplace:	Canada

Research Interests:

Expression changes during cancer progression

Publications

Shadeo A, Chari R, Lonergan KM, Pusic A, Miller D, Ehlen T, Van Niekerk D, Matisic J, Richards-Kortum R, Follen M, Guillaud M, Lam WL, MacAulay C. (2008) Up regulation in gene expression of chromatin remodelling factors in cervical intraepithelial neoplasia. BMC Genomics 9:64, 1-14. [PMID: 18248679]

Chari R, Lonergan KM, Ng RT, MacAulay C, Lam WL, Lam S. (2007) Effect of active smoking on the human bronchial epithelium transcriptome. BMC Genomics 8:297, 1-13. [PMID: 17727719]

Shadeo A, Chari R, Vatcher G, Campbell J, Lonergan KM, Matisic J, van Niekerk D, Ehlen T, Miller D, Follen M, Lam WL, MacAulay C. Comprehensive serial analysis of gene expression of the cervical transcriptome. (2007) BMC Genomics. 8:142, 1-11. [PMID: 17543121]

Lonergan KM, Chari R, Deleeuw RJ, Shadeo A, Chi B, Tsao MS, Jones S, Marra M, Ling V, Ng R, Macaulay C, Lam S, Lam WL. (2006) Identification of novel lung genes in bronchial epithelium by serial analysis of gene expression. Am J Respir Cell Mol Biol. 35: 651-61. [PMID: 16809635]

Kaelin WG, Iliopoulos O, Lonergan KM, Ohh M. Functions of the von Hippel-Lindau tumour suppressor protein. (1998) J Intern Med. 243: 535-9. [PMID: 9681855]

Ohh M, Yauch RL, Lonergan KM, Whaley JM, Stemmer-Rachamimov AO, Louis DN, Gavin BJ, Kley N, Kaelin WG Jr, Iliopoulos O. (1998) The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix. Mol Cell. 1: 959-68. [PMID: 9651579]

Pause A, Lee S, Lonergan KM, Klausner RD. (1998) The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal. Proc Natl Acad Sci U S A. 95: 993-8. [PMID: 9448273]

Lonergan KM, Iliopoulos O, Ohh M, Kamura T, Conaway RC, Conaway JW, Kaelin WG Jr. (1998) Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2. Mol Cell Biol. 18: 732-41. [PMID: 9447969]

Lonergan KM, Gray MW. (1996) Expression of a continuous open reading frame encoding subunits 1 and 2 of cytochrome c oxidase in the mitochondrial DNA of Acanthamoeba castellanii. J Mol Biol. 257: 1019-30. [PMID: 8632465]

Turmel M, Cote V, Otis C, Mercier JP, Gray MW, Lonergan KM, Lemieux C. (1995) Evolutionary transfer of ORF-containing group I introns between different subcellular compartments (chloroplast and mitochondrion). Mol Biol Evol. 12: 533-45. [PMID: 7659010]

Burger G, Plante I, Lonergan KM, Gray MW. (1995) The mitochondrial DNA of the amoeboid protozoon, Acanthamoeba castellanii: complete sequence, gene content and genome organization. J Mol Biol. 245: 522-37. [PMID: 7844823]

Lonergan KM, Gray MW. (1994) The ribosomal RNA gene region in Acanthamoeba castellanii mitochondrial DNA. A case of evolutionary transfer of introns between mitochondria and plastids? J Mol Biol. 239: 476-99. [PMID: 8006963]

Lonergan KM, Gray MW. (1993) Predicted editing of additional transfer RNAs in Acanthamoeba castellanii mitochondria. Nucleic Acids Res. 21: 4402. [PMID: 8415006]

Lonergan KM, Gray MW. (1993) Editing of transfer RNAs in Acanthamoeba castellanii mitochondria. Science. 259: 812-6. [PMID: 8430334]

Rajaraman R, Lonergan K. (1982) Fibronectin distribution pattern and the three-dimensional growth behavior of mammalian cells under anchorage-independent conditions. Exp Cell Biol. 50: 2-12. [PMID: 7037497]

Lazier CB, Richman J, Lonergan K. (1984) The effect of molybdate on the intracellular distribution of estrogen receptor in mammary tumors. Breast Cancer Res Treat. 4: 19-26. [PMID: 6697008]

Lazier CB, Lonergan K, Mommsen TP. (1985) Hepatic estrogen receptors and plasma estrogen-binding activity in the Atlantic salmon. Gen Comp Endocrinol. 57:234-45. [PMID: 3979805]

 BCCRC | Cancer Genetics | Lam Lab | Lab Publications |

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