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Sylvia Ng

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Peer-Reviewed Papers
Peer-Reviewed Papers | Books (and Chapters)

    2008

  1. Baker JHE, Lam J, Kyle AH, Sy J, Oliver T, Co S, Dragowska WH, Ramsay E, Anantha M, Ruth TJ, Adam MJ, Yung A, Kozlowski P, Minchinton AI, Ng SSW, Bally MB and Yapp DTT (2008). Irinophore CTM, A Novel Nano-Formulation of Irinotecan, Alters Tumor Vascular Function, and Enhances the Distribution of 5-FU and Doxorubicin Clin Cancer Res 2008 Nov 15:14(22):7260-7l (2008).
     [View Abstract - PubMed 19010842]

  2. 2006

  3. Ng SS, Sparreboom A, Shaked Y, Lee C, Man S, Desai N, Soon-Shiong P, Figg WD, Kerbel RS. Influence of Formulation Vehicle on Metronomic Taxane Chemotherapy: Albumin-Bound versus Cremophor EL-Based Paclitaxel. Clin Cancer Res. 12(14):4331-8. (2006).
     [View Abstract - PubMed 16857808]

  4. 2004

  5. Lepper ER, Ng SS, Gutschow M, Weiss M, Hauschildt S, Hecker TK, Luzzio FA, Eger K, Figg WD. Comparative molecular field analysis and comparative molecular similarity indices analysis of thalidomide analogues as angiogenesis inhibitors. J Med Chem. 47(9):2219-27. (2004).
     [View Abstract - PubMed 15084120]

  6. McDonald DM, Teicher BA, Stetler-Stevenson W, Ng SS, Figg WD, Folkman J, Hanahan D, Auerbach R, O'Reilly M, Herbst R, Cheresh D, Gordon M, Eggermont A, Libutti SK. Report from the society for biological therapy and vascular biology faculty of the NCI workshop on angiogenesis monitoring. J Immunother. 27(2):161-75. (2004).
     [View Abstract - PubMed 14770088]

  7. Ng SS, Figg WD. Upregulation of endogenous angiogenesis inhibitors: a mechanism of action of metronomic chemotherapy. Cancer Biol Ther. 3(12):1212-3. Epub 2004 Dec 15. (2004).
     [View Abstract - PubMed 15662130]

  8. Ng SS, Figg WD, Sparreboom A. Taxane-mediated antiangiogenesis in vitro: influence of formulation vehicles and binding proteins. Cancer Res. 64(3):821-4. (2004).
     [View Abstract - PubMed 14871806]

  9. Ng SS, MacPherson GR, Gutschow M, Eger K, Figg WD. Antitumor effects of thalidomide analogs in human prostate cancer xenografts implanted in immunodeficient mice. Clin Cancer Res. 10(12 Pt 1):4192-7. (2004).
     [View Abstract - PubMed 15217957]

  10. Tohnya TM, Ng SS, Dahut WL, Wright JJ, Arlen PM, Gulley JL, Parker C, Zeldis J, Figg WD. A phase I study of oral CC-5013 (lenalidomide, Revlimid), a thalidomide derivative, in patients with refractory metastatic cancer. Clin Prostate Cancer. 2(4):241-3. (2004).
     [View Abstract - PubMed 15072608]

  11. 2003

  12. Luzzio FA, Mayorov AV, Ng SS, Kruger EA, Figg WD. Thalidomide metabolites and analogues. 3. Synthesis and antiangiogenic activity of the teratogenic and TNFalpha-modulatory thalidomide analogue 2-(2,6-dioxopiperidine-3-yl)phthalimidine. J Med Chem. 46(18):3793-9. (2003).
     [View Abstract - PubMed 12930142]

  13. Macpherson GR, Ng SS, Forbes SL, Melillo G, Karpova T, McNally J, Conrads TP, Veenstra TD, Martinez A, Cuttitta F, Price DK, Figg WD. Anti-angiogenic activity of human endostatin is HIF-1-independent in vitro and sensitive to timing of treatment in a human saphenous vein assay. Mol Cancer Ther. 2(9):845-54. (2003).
     [View Abstract - PubMed 14555703]

  14. Ng SS, Figg WD. Antitumor activity of herbal supplements in human prostate cancer xenografts implanted in immunodeficient mice. Anticancer Res. 23(5A):3585-90. (2003).
     [View Abstract - PubMed 14666653]

  15. Ng SS, Gutschow M, Weiss M, Hauschildt S, Teubert U, Hecker TK, Luzzio FA, Kruger EA, Eger K, Figg WD. Antiangiogenic activity of N-substituted and tetrafluorinated thalidomide analogues. Cancer Res. 63(12):3189-94. (2003).
     [View Abstract - PubMed 12810647]

  16. 2002

  17. Macpherson GR, Ng SS, Lakhani NJ, Price DK, Venitz J, Figg WD. Antiangiogenesis therapeutic strategies in prostate cancer. Cancer Metastasis Rev. 21(1):93-106. (2002).
     [View Abstract - PubMed 12400998]

  18. Ng SS, Brown M, Figg WD. Thalidomide, an antiangiogenic agent with clinical activity in cancer. Biomed Pharmacother. 56(4):194-9. (2002).
     [View Abstract - PubMed 12109812]

  19. Ng SS, Tsao MS, Nicklee T, Hedley DW. Effects of the epidermal growth factor receptor inhibitor OSI-774, Tarceva, on downstream signaling pathways and apoptosis in human pancreatic adenocarcinoma. Mol Cancer Ther. 1(10):777-83. (2002).
     [View Abstract - PubMed 12492110]

  20. 2001

  21. Ng SS, Tsao MS, Nicklee T, Hedley DW. Wortmannin inhibits pkb/akt phosphorylation and promotes gemcitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice. Clin Cancer Res. 7(10):3269-75. (2001).
     [View Abstract - PubMed 11595724]

  22. 2000

  23. Ng SS, Pang CC. In vivo venodilator action of fenoldopam, a dopamine D(1)-receptor agonist. Br J Pharmacol. 129(5):853-8. (2000).
     [View Abstract - PubMed 10696081]

  24. Ng SSW, Tsao MS, Chow S, Hedley DW. Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells. Cancer Res. 60(19):5451-5. (2000).
     [View Abstract - PubMed 11034087]

Books (and Chapters)
Peer-Reviewed Papers | Books (and Chapters)

    2008

  1. Syliva S.W. Ng and Kim N. Chi. Chapter 27: Surrogates for Clinical Development In: Angiogenesis: An integrated approach from science to medicine (2008).

  2. 2002

  3. Macpherson, G.R., Ng, S.S.W., Lakhani, N.J., Price, D.K., Venitz, J. and Figg, W.D. . Antiangiogenesis therapeutic strategies in prostate cancer. In Cher, M.L. and Raz., A. (eds), Prostate Cancer: New Horizons in Research and Treatment, 317-330. Kluwer Academic Publishers, the Netherlands. (2002).


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