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Kirsten Skov
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Peer-Reviewed Papers
2005
Guns ES, Xie X, Fedoruk M, Madera C, Cowell S, Mayer LD, Skov K, Gleave ME, Kozlowski P.
pH modulation using CsCl enhances therapeutic effects of vitamin D in LNCaP tumor bearing mice.
Prostate. 64(3):316-22.
(2005).
[View Abstract - PubMed 15754319] Request Paper
2004
Dragowska WH, Warburton C, Yapp DT, Minchinton AI, Hu Y, Waterhouse DN, Gelmon K, Skov K, Woo J, Masin D, Huxham LA, Kyle AH, Bally MB.
HER-2/neu overexpression increases the viable hypoxic cell population within solid tumors without causing changes in tumor vascularization.
Mol Cancer Res. 2(11):606-19.
(2004).
[View Abstract - PubMed 15561777] Request Paper
Skov K, Adomat H, Bowden M, Dragowska W, Gleave M, Koch CJ, Woo J, Yapp DT.
Hypoxia in the androgen-dependent Shionogi model for prostate cancer at three stages.
Radiat Res. 162(5):547-53.
(2004).
[View Abstract - PubMed 15624309] Request Paper
de Boer JG, Yang H, Holcroft J, Skov K.
Chemoprotection against N-nitrosomethylbenzylamine-induced mutation in the rat esophagus.
Nutr Cancer. 50(2):168-73.
(2004).
[View Abstract - PubMed 15623463] Request Paper
2003
Zellweger T, Kiyama S, Chi K, Miyake H, Adomat H, Skov K, Gleave ME.
Overexpression of the cytoprotective protein clusterin decreases radiosensitivity in the human LNCaP prostate tumour model.
BJU Int. 92(4):463-9.
(2003).
[View Abstract - PubMed 12930442] Request Paper
2002
Barret JM, Etievant C, Baudouin C, Skov K, Charveron M, Hill BT.
F 11782, a novel catalytic inhibitor of topoisomerases I and II, induces atypical, yet cytotoxic DNA double-strand breaks in CHO-K1 cells.
Anticancer Res 22(1A):187-92.
(2002).
[View Abstract - PubMed 12017285] Request Paper
Zellweger T, Chi K, Miyake H, Adomat H, Kiyama S, Skov K, Gleave ME.
Enhanced radiation sensitivity in prostate cancer by inhibition of the cell survival protein clusterin.
Clin Cancer Res. 8(10):3276-84.
(2002).
[View Abstract - PubMed 12374699] Request Paper
2001
Bebb DG, Warrington PJ, de Jong G, Yu Z, Moffat JA, Skov K, Spacey S, Gelmon K, Glickman BW.
Radiation induced apoptosis in ataxia telangiectasia homozygote, heterozygote and normal cells.
Mutat Res 476(1-2):13-20.
(2001).
[View Abstract - PubMed 11336979] Request Paper
1999
Baird IR, Rettig SJ, James BR and Skov KA.
Synthesis and X-ray structural characterization of the ruthenium β-Diketonato complexes: Ru(hfac)3, cis-Ru(hfac)2(MeCN)2 and cis-Ru(hfac)(acac)(MeCN)2.
Can. J. Chem. 77:1821-1833, 1999.
(1999). Request Paper
Kachur AV, Dolbier WR Jr, Evans SM, Shiue CY, Shiue GG, Skov KA, Baird IR, James BR, Li AR, Roche A, Koch CJ.
Synthesis of new hypoxia markers EF1 and [18F]-EF1.
Appl Radiat Isot 51(6):643-50.
(1999).
[View Abstract - PubMed 10581679] Request Paper
Posakony JJ, Pratt RC, James BR and Skov KA.
Porphyrins incorporating heterocyclic N-oxides: (Oxidopyridyl)porphyrins, porphyrin N-Oxides, and a tirapazamine-porphyrin conjugate.
Can. J. Chem. 77:182-198
(1999). Request Paper
Skov KA.
Perspectives on the adaptive response from studies on the response to low radiation doses (or to cisplatin) in mammalian cells.
Hum Exp Toxicol 18(7):447-51.
(1999).
[View Abstract - PubMed 10454076] Request Paper
Skov KA.
Radioresponsiveness at low doses: hyper-radiosensitivity and increased radioresistance in mammalian cells.
Mutat Res 430(2):241-53.
(1999).
[View Abstract - PubMed 10631339] Request Paper
1998
Baird IR, Rettig S, Skov KA, James BR and Koch CJ.
An effective synthetic route to EF5.
Synthetic Communications, 28:3701-3709,
(1998). Request Paper
Baird IR, Rettig SJ, James BR and Skov KA .
Synthesis and characterization of homoleptic ruthenium (II) imidazole complexes, and a carbonyl species derived by CO abstraction from DMF.
Can. J. Chem. 76:1379-1388
(1998). Request Paper
Matthews JB, Harrison A, Palcic B, Skov K.
Automated fluorescence microscopic measurement of apoptosis frequency following ionizing radiation exposure in cultured mammalian cells.
Int J Radiat Biol 73(6):629-39.
(1998).
[View Abstract - PubMed 9690681] Request Paper
Skov KA, Adomat H, Farrell NP, Matthews JB.
Assessment of toxicity of bis-platinum complexes in hypoxic and aerobic cells.
Anticancer Drug Des 13(3):207-20.
(1998).
[View Abstract - PubMed 9595034] Request Paper
1997
Guillaud M, Matthews JB, Harrison A, MacAulay C, Skov K.
A novel image cytometric method for quantitation of immunohistochemical staining of cytoplasmic antigens.
Anal Cell Pathol 14(2):87-99.
(1997).
[View Abstract - PubMed 9313824] Request Paper
Marples B, Lambin P, Skov KA, Joiner MC.
Low dose hyper-radiosensitivity and increased radioresistance in mammalian cells.
Int J Radiat Biol 71(6):721-35.
(1997).
[View Abstract - PubMed 9246186] Request Paper
Yapp DT, Rettig SJ, James BR and Skov KA .
Bidentate sulfoxide complexes of Ruthenium (II) and their preliminary biological activity in vitro.
Inorg. Chem. 36: 5635-5641
(1997). Request Paper
1996
Grigg A, Szer J, Skov K, Barnett M.
Multi-organ dysfunction associated with high-dose carboplatin therapy prior to autologous transplantation.
Bone Marrow Transplant 17(1):67-74.
(1996).
[View Abstract - PubMed 8673058] Request Paper
James BR, Meng GG, Posakony JJ, Ravensbergen JA, Ware CJ and Skov KA.
Porphyrins and Metalloporphyrins: Potential hypoxic agents.
Metal-based Drugs 3: 85-89
(1996). Request Paper
Joiner MC, Lambin P, Malaise EP, Robson T, Arrand JE, Skov KA, Marples B.
Hypersensitivity to very-low single radiation doses: its relationship to the adaptive response and induced radioresistance.
Mutat Res 358(2):171-83.
(1996).
[View Abstract - PubMed 8946022] Request Paper
Marples B, Adomat H, Koch CJ, Skov KA.
Response of V79 cells to low doses of X-rays and negative pi-mesons: clonogenic survival and DNA strand breaks.
Int J Radiat Biol 70(4):429-36.
(1996).
[View Abstract - PubMed 8862454] Request Paper
Marples B, Skov KA.
Small doses of high-linear energy transfer radiation increase the radioresistance of Chinese hamster V79 cells to subsequent X irradiation.
Radiat Res 146(4):382-7.
(1996).
[View Abstract - PubMed 8927710] Request Paper
Matthews J, Adomat H, Farrell N, King P, Koch C, Lord E, Palcic B, Poulin N, Sangulin J, Skov K.
Immunocytochemical labelling of aerobic and hypoxic mammalian cells using a platinated derivative of EF5.
Br J Cancer Suppl 27:S200-3.
(1996).
[View Abstract - PubMed 8763880] Request Paper
1995
Farrell N, Appleton TG, Qu Y, Roberts JD, Fontes AP, Skov KA, Wu P, Zou Y.
Effects of geometric isomerism and ligand substitution in bifunctional dinuclear platinum complexes on binding properties and conformational changes in DNA.
Biochemistry 34(47):145480-6.
(1995).
[View Abstract - PubMed 7492537] Request Paper
Skov K, Koch CJ and Marples B .
Further investigations into the nature of the trigger of increased radioresistance: the effect of 14C and 3H thymidine incorporation on low dose hypersensitivity.
Proceedings of workshop on "Radiation Damage in DNA: Relationships at early times". Eds. J. Zimbrick, A. Fucarielli, Batelle Publishing, Columbus, Ohio, p.441-447, 1995.
(1995). Request Paper
Skov K, Koch CJ and Marples B .
Further investigations into the nature of the trigger of increased radioresistance: the effect of 14C and 3H thymidine incorporation on low dose hypersensitivity.
Proceedings of workshop on "Radiation Damage in DNA: Relationships at early times". Eds. J. Zimbrick, A. Fucarielli, Batelle Publishing, Columbus, Ohio, p.441-447, 1995.
(1995). Request Paper
Skov KA, Marples B.
Increased radioresistance at clinical doses: Investigations from the survival perspective.
Radiat Oncol Investigations 2:201-211
(1995). Request Paper
1994
Koch CJ, Skov KA.
Enhanced radiation-sensitivity by preincubation with nitroimidazoles: effect of glutathione depletion.
Int J Radiat Oncol Biol Phys 29(2):345-9.
(1994).
[View Abstract - PubMed 8195031] Request Paper
Marples B, Adomat H, Billings PC, Farrell NP, Koch CJ, Skov KA.
Recognition of platinum-induced DNA damage by nuclear proteins: screening for mechanisms.
Anticancer Drug Des 9(5):389-99.
(1994).
[View Abstract - PubMed 7945723] Request Paper
Marples B, Joiner MC, Skov KA.
The effect of oxygen on low-dose hypersensitivity and increased radioresistance in Chinese hamster V79-379A cells.
Radiat Res 138(1 Suppl):S17-20.
(1994).
[View Abstract - PubMed 8146317] Request Paper
Marples B, Lam GK, Zhou H, Skov KA.
The response of Chinese hamster V79-379A cells exposed to negative pi-mesons: evidence that increased radioresistance is dependent on linear energy transfer.
Radiat Res 138(1 Suppl):S81-4.
(1994).
[View Abstract - PubMed 8146334] Request Paper
Meng G, James BR and Skov KA .
Porphyrin chemistry pertaining to the design of anti-cancer drugs; part I, the synthesis of porphyrins containing meso-pyridyl and meso-substituted phenyl functional groups.
Can. J. Chem. 72: 1894-1909
(1994). Request Paper
Meng G, James BR, Skov KA and Korbelik M.
Porphyrin chemistry pertaining to the design of anti-cancer drugs; part II, the synthesis and in vitro tests of water-soluble porphyrins containing in the meso-positions, the functional groups: 4-methylpyridinium, or 4-sulfonatophenyl, in combination with phenyl, 4-pyridyl, 4-nitrophenyl or 4-aminophenyl.
Can. J. Chem. 72: 2447-2457
(1994). Request Paper
Poulin NM, Matthews JB, Skov KA, Palcic B.
Effects of fixation method on image cytometric measurement of DNA content and distribution in cells stained for fluorescence with propidium iodide.
J Histochem Cytochem 42(8):1149-56.
(1994).
[View Abstract - PubMed 8027534] Request Paper
Skov K, Koch CJ and Marples B .
Effect of etanidazole on absolute sensitivity and increased radioresistance in hypoxic cells at low doses.
Radiat. Oncol. Invest. 2: 164-170
(1994). Request Paper
Skov K, Marples B, Matthews JB, Joiner MC, Zhou H.
A preliminary investigation into the extent of increased radioresistance or hyper-radiosensitivity in cells of hamster cell lines known to be deficient in DNA repair.
Radiat Res 138(1 Suppl):S126-9.
(1994).
[View Abstract - PubMed 8146315] Request Paper
Skov K, Zhou H, Marples B.
The effect of two topoisomerase inhibitors on low-dose hypersensitivity and increased radioresistance in Chinese hamster V79 cells.
Radiat Res 138(1 Suppl):S117-20.
(1994).
[View Abstract - PubMed 8146313] Request Paper
Skov KA.
Molecular, cellular, and genetic basis of radiosensitivity at low doses: a case of inducible repair?
Radiat Res 138(1 Suppl):S1-4.
(1994).
[View Abstract - PubMed 8146308] Request Paper
Skov KA, Adomat H, Doedee M, Farrell N.
Radiosensitizing and toxic properties of quinoline and nitroquinoline complexes of platinum [PtCl2(NH3)quinoline].
Anticancer Drug Des 9(2):103-17.
(1994).
[View Abstract - PubMed 8166927] Request Paper
Skov KA, MacPhail HS, Marples B.
The effect of radiosensitizers on the survival response of hypoxic mammalian cells: the low X-ray dose region, hypersensitivity and induced radioresistance.
Radiat Res 138(1 Suppl):S113-6.
(1994).
[View Abstract - PubMed 8146312] Request Paper
Skov KA, MacPhail S.
Low concentrations of nitroimidazoles: effective radiosensitizers at low doses.
Int J Radiat Oncol Biol Phys 29(1):87-93.
(1994).
[View Abstract - PubMed 8175450] Request Paper
Spadinger I, Marples B, Matthews J, Skov K.
Can colony size be used to detect low-dose effects?
Radiat Res 138(1 Suppl):S21-4.
(1994).
[View Abstract - PubMed 8146318] Request Paper
1993
Jaswal JS, Yapp DTT, Rettig SJ, James BR and Skov KA .
Routes to ruthenium(II) bromo(sulfoxide) complexes, including the synthesis and structural characterization of a neutral dilithium/diruthenium(II) complex containing terminal and bridging tetramethylenesulfoxide ligands.
Inorg. Chim. Acta. 207: 97-103
(1993). Request Paper
Koch CJ and Skov KA .
Letter to the Editor - Response to R.C. Richmond.
Radiat. Res. 136: 300
(1993). Request Paper
Korbelik M, Krosl G, Adomat H, Skov KA.
The effect of differentiation on photosensitizer uptake by HL60 cells.
Photochem Photobiol 58(5):670-5.
(1993).
[View Abstract - PubMed 8284322] Request Paper
Matthews JB, Adomat H, Skov KA.
The effect of hypoxia on cytotoxicity, accumulation and DNA binding of cisplatin in Chinese hamster ovary cells.
Anticancer Drugs 4(4):463-70.
(1993).
[View Abstract - PubMed 8400349] Request Paper
Skov KA, Adomat H, Farrell NP.
Radiosensitization by nickel lapachol.
Int J Radiat Biol 64(6):707-13.
(1993).
[View Abstract - PubMed 7903338] Request Paper
Walter P, Korbelik M, Spadinger I, Skov KA.
Investigation into mechanisms of the interaction between platinum complexes and irradiation at low (~ 2 Gy) doses in hypoxic cells. I. The role of single-strand breaks.
Radiat Oncol Investigations 1:137-147
(1993). Request Paper
1992
Billings PC, Davis RJ, Engelsberg BN, Skov KA, Hughes EN.
Characterization of high mobility group protein binding to cisplatin-damaged DNA.
Biochem Biophys Res Commun 188(3):1286-94.
(1992).
[View Abstract - PubMed 1445361] Request Paper
Jaswal JS, Yapp DTT, Rettig SJ, James BR and Skov KA .
A diruthenium-dilithium complex containing four different bonding types of tetramethylenesulfoxide ligands.
J. Chem. Soc. Chem. Comm. 1528-9
(1992). Request Paper
Koch CJ, Skov KA.
Comparisons of cellular radiation response using absolute rather than relative parameters.
Radiat Res 132(1):40-9.
(1992).
[View Abstract - PubMed 1410272] Request Paper
Skov KA, MacPhail HS.
Effect of BSO on the radiation response at low (0-4 Gy) doses.
Int J Radiat Oncol Biol Phys 22(3):533-6.
(1992).
[View Abstract - PubMed 1346532] Request Paper
1991
Rochon FD, Kong PC, Melanson R, Skov KA and Farrell NP .
Characterization and properties of monoammine nitroimidazole complexes of platinum [PtCl2(NH3)(NO2Im)]. Crystal and molecular structure of cis-Amminedichloro (1-{(((2-hydroxyethyl)amino)carbonyl)methyl}-2-nitroimidazole)platinum (II).
Inorg. Chem. 30: 4531-4535
(1991). Request Paper
Skov K, MacPhail S.
Interaction of platinum drugs with clinically relevant x-ray doses in mammalian cells: a comparison of cisplatin, carboplatin, iproplatin, and tetraplatin.
Int J Radiat Oncol Biol Phys 20(2):221-5.
(1991).
[View Abstract - PubMed 1991682] Request Paper
1990
Chaplin DJ, Trotter MJ, Skov KA, Horsman MR.
Modification of tumour radiation response in vivo by the benzamide analogue pyrazinamide.
Br J Cancer 62(4):561-6.
(1990).
[View Abstract - PubMed 2145963] Request Paper
Skov KA, Adomat H, Chaplin DJ, Farrell NP.
Toxicity of [PtCl2(NH3)L] in hypoxia; L = misonidazole or metronidazole.
Anticancer Drug Des 5(1):121-8.
(1990).
[View Abstract - PubMed 2156514] Request Paper
Skov KA, Farrell NP.
Radiosensitization by metal complexes of 4(5)-nitroimidazole.
Int J Radiat Biol 57(5):947-58.
(1990).
[View Abstract - PubMed 1970996] Request Paper
Yapp DTT, Jaswal J, Rettig SJ, James BR and Skov KA.
Synthesis and structural characterization of Cis-dichlorotetrakis(tetramethylenesulfoxide-S) ruthenium(II) and Mer-trichlorotris (tetrahydrothiophene)ruthenium(III).
Inorg. Chim. Acta. 177: 199-208
(1990). Request Paper
1989
Chan PKL, James BR, Frost, DC, Chan PKH, Hu H-L and Skov KA.
Effects of halide (X) and sulphoxide (R2SO) replacement within the ruthenium(II) nitroimidazole complexes, RuX2(R2SO)m(nitroimidazole)n, m=1-3, n=1 or 2: their characterization, solution chemistry, radiosensitizing activity, and related properties.
Can. J. Chem. 67: 508-516
(1989). Request Paper
Korbelik M, Skov KA.
Inactivation of hypoxic cells by cisplatin and radiation at clinically relevant doses.
Radiat Res 119(1):145-56.
(1989).
[View Abstract - PubMed 2756105] Request Paper
Skov KA .
Invited Workshop Summary: DNA targeted hypoxic cytotoxins and radiosensitizers.
Int. J. Radiat. Biol. 56: 387-393
(1989). Request Paper
Skov KA, Korbelik M, Palcic B.
The interaction of trans-DDP [PtCl2(NH3)2] with low doses of radiation in mammalian cells.
Int J Radiat Oncol Biol Phys 16(5):1281-4.
(1989).
[View Abstract - PubMed 2715080] Request Paper
1988
Chan PKL, Chan PKH, Frost DC, James BR and Skov KA.
Ruthenium(II) complexes of 4-nitroimidazoles: their characterization, solution chemistry and radiosensitizing activity.
Can. J. Chem. 66: 117-122
(1988). Request Paper
Farrell NP, de Almeida SG and Skov KA .
Bis(platinum) complexes containing two platinum cis-Diammine units.
J. Am. Chem. Soc. 110: 5018-5019
(1988). Request Paper
1987
Chan PK, Skov KA, James BR.
Further studies on toxic and radiosensitizing properties of ruthenium complexes of 4-nitroimidazoles.
Int J Radiat Biol Relat Stud Phys Chem Med 52(1):49-55.
(1987).
[View Abstract - PubMed 3496310] Request Paper
Farrell NP and Skov KA .
Radiosensitizers targeted to DNA using platinum. Synthesis, characterization and DNA binding of cis-[PtCl2(NH3)(radiosensitizer)].
J. Chem. Soc. Chem. Comm. 1043-1044, 1987.
(1987). Request Paper
Skov KA.
Modification of radiation response by metal complexes: a review with emphasis of nonplatinum studies.
Radiat Res 112(2):217-42.
(1987).
[View Abstract - PubMed 3317478] Request Paper
Skov KA, Adomat H, Konway DC, Farrell NP.
Assessment of DNA binding of platinum-radiosensitizer complexes by inhibition of restriction enzymes.
Chem Biol Interact 62(2):117-29.
(1987).
[View Abstract - PubMed 3036382] Request Paper
Skov KA, Farrell NP.
Binding mode of 2-amino-5-nitrothiazole (ANT) in platinum complexes, trans-[PtCl2(ANT)2], affects DNA binding, toxicity and radiosensitizing ability.
Int J Radiat Biol Relat Stud Phys Chem Med 52(2):289-97.
(1987).
[View Abstract - PubMed 3497126] Request Paper
Skov KA, Farrell NP, Adomat H.
Platinum complexes with one radiosensitizing ligand [PtCl2(NH3) (sensitizer)]: radiosensitization and toxicity studies in vitro.
Radiat Res 112(2):273-82.
(1987).
[View Abstract - PubMed 3685256] Request Paper
Skov KA, Kumi C, Rootman J, Bussanich N, Fellenz MO.
Response of an ocular melanoma to subconjunctival injection of 5-thio-D-glucose or cis-platin.
Br J Cancer 55(5):499-502.
(1987).
[View Abstract - PubMed 3606943] Request Paper
1986
Chan PK, Skov KA, James BR, Farrell NP.
Chromosome-damaging activity of a ruthenium radiosensitizer, RuCl2 (DMSO)2 (4-nitroimidazole)2, in Chinese hamster ovary cells in vitro.
Chem Biol Interact 59(3):247-54.
(1986).
[View Abstract - PubMed 3769054] Request Paper
Chan PK, Skov KA, James BR, Farrell NP.
A new ruthenium radiosensitizer: RuCl2(DMSO)2(4-nitroimidazole)2.
Int J Radiat Oncol Biol Phys 12(7):1059-62.
(1986).
[View Abstract - PubMed 3744927] Request Paper
1984
Farrell NP, Gomes Carneiro T, Einstein FWB, Jones T and Skov KA.
Synthesis and characterization of nitroimidazole complexes of platinum and palladium and the crystal and molecular structure of trans-dichlorobis(misonidazole)Platinum(II).
Inorganica Chimica Acta 92: 61-66
(1984). Request Paper
Skov KA.
The contribution of hydroxyl radical to radiosensitization: a study of DNA damage.
Radiat Res 99(3):502-10.
(1984).
[View Abstract - PubMed 6089257] Request Paper
Skov KA.
Repair of DNA breaks after irradiation in misonidazole or oxygen.
Int J Radiat Oncol Biol Phys 10(8):1199-202.
(1984).
[View Abstract - PubMed 6469740] Request Paper
1982
Korbelik M, Palcic B, Skov K, Skarsgard L.
Misonidazole and potentially lethal damage.
Int J Radiat Oncol Biol Phys 8(3-4):461-4.
(1982).
[View Abstract - PubMed 7201990] Request Paper
Skov KA, Korbelik M, Palcic B, Skarsgard LD.
Energy and misonidazole toxicity: the effects of 5-thio-D-glucose.
Int J Radiat Oncol Biol Phys 8(3-4):697-700.
(1982).
[View Abstract - PubMed 7107401] Request Paper
Skov KA, Palcic B, Skarsgard LD.
DNA damage and radiosensitizers: M. luteus sensitive sites for misonidazole-TAN combination.
Radiat Res 92(1):113-9.
(1982).
[View Abstract - PubMed 7134378] Request Paper
1981
Skov KA, Palcic B, Skarsgard LD.
Modification of the action of misonidazole. III. The effect of diamide on toxicity and radiosensitization.
Int J Radiat Biol Relat Stud Phys Chem Med 40(4):335-45.
(1981).
[View Abstract - PubMed 6975248] Request Paper
1980
Martin PW, Kalfas CA and Skov K.
Study of conformational changes in bovine serum albumin by perturbed angular correlations.
Nuclear Instruments and Methods 171: 603-606
(1980). Request Paper
Skov KA, Palcic B, Harrison IE, Skarsgard LD.
Modification of the action of misonidazole. II. Effect of TAN on radiosensitization.
Int J Radiat Biol Relat Stud Phys Chem Med 37(6):613-20.
(1980).
[View Abstract - PubMed 6968296] Request Paper
Skov KA, Palcic B, Harrison IE, Skarsgard LD.
Modification of the action of misonidazole. I. Effect of TAN on toxicity.
Int J Radiat Biol Relat Stud Phys Chem Med 37(6):601-11.
(1980).
[View Abstract - PubMed 6968295] Request Paper
Skov KA, Palcic B, Skarsgard LD.
Lesions in DNA of hypoxic mammalian cells irradiated in the presence of TAN.
Int J Radiat Biol Relat Stud Phys Chem Med 37(5):529-36.
(1980).
[View Abstract - PubMed 6967466] Request Paper
1979
Skov KA, Palcic B, Skarsgard LD.
Radiosensitization of mammalian cells by misonidazole and oxygen: DNA damage exposed by Micrococcus luteus enzymes.
Radiat Res 79(3):591-600.
(1979).
[View Abstract - PubMed 482614] Request Paper
1978
Martin PW, Kalfas CA and Skov K.
Helix-random coil transition in polyglutamic acid observed by perturbed angular correlations of gamma rays.
Chem. Phys. Letters 57: 279-280
(1978). Request Paper
Martin PW, Kalfas CA and Skov K.
Molecular dynamics of polyglutamic acid studied by perturbed angular correlation of gamma rays.
J. Chem. Phys. 69: 1958-1960
(1978). Request Paper
Martin PW, Skov K.
In-111 transferrin labeling studied by perturbed angular correlations.
J Nucl Med 19(10):1171-4.
(1978).
[View Abstract - PubMed 722329] Request Paper
1975
Skov KA, Vonderschmitt DJ.
Kinetics of iron and copper catalysis of ascorbate oxidation.
Bioinorg Chem 4(3):199-213.
(1975).
[View Abstract - PubMed 236045] Request Paper
1971
Skov K, Williams GR.
Correlations between optical rotatory dispersion and other spectroscopic properties of ferricytochrome c (horse heart).
Can J Biochem 49(4):441-7.
(1971).
[View Abstract - PubMed 5102736] Request Paper
1969
Skov K, Hofmann T, Williams GR.
The nitration of cytochrome c.
Can J Biochem 47(7):750-2.
(1969).
[View Abstract - PubMed 5815946] Request Paper
1966
Myers DK, Skov K.
Nucleic acid synthesis in x-irradiated thymocytes.
Can J Biochem 44(6):839-52.
(1966).
[View Abstract - PubMed 4224082] Request Paper
1965
Stevens WH and Skov K.
A rapid spectrophotometic method for determining parts per million of morpholine in boiler water.
Analyst 90: 182-183
(1965). Request Paper
Non Peer-Reviewed Papers
1999
Skov KA.
Invited response to issues associated with the adaptive response: perspectives from studies in mammalian cells on the response to low radiation doses or to cisplatin. (Invited comments)
BELLE Newsletter 7:26-30
(1999). Request Paper
Books (and Chapters)
In Press
Skov KA .
CRP#7574/CF Radioresistance at clinical radiation doses: an investigation of IRR (increased radioresistance).
The International Atomic Energy Agency's Co-ordinated Research Programme on Radiation Responsiveness Criteria for Human Tumours as a Determinant for Therapeutic Modality Planning. IAEA TEDOC.
(In Press). Request Paper
2002
Bhattathiri VN, Cho CK, Dobrowsky W, Gasinska A, Hannan M, Levin CV, Nakano T, Pillai R, Schwartz JL, Skov K, Song C, Streffer C, Tatsuzaki H, Wei K and West C..
Predictive assays and their role in selection of radiation as the therapeutic modality
The International Atomic Energy Agency's Coordinated Research Programme, IAEA-TECDOC-1297, IAEA July 2002, Editors: Tatsuzaki H, Skov K and Dobrowsky W
(2002). Request Paper
2000
Skov KA .
A survey of radiosensitizing properties of bisplatinum complexes in hypoxic mammalian cells.
Invited Book Chapter in book: Recent Research Developments in Inorganic Chemistry Vol.2:57-67, 2000. Managing Editor: S.G. Pandalai, Publisher: Transworld Research Network.
(2000). Request Paper
1992
Marples B, Joiner MC and Skov KA.
An X-ray inducible repair response: Evidence from high resolution survival measurements in air and hypoxia.
In: Low Dose Irradiation and Biological Defense Mechanisms, T. Sugahara, L.A. Sagan and T. Aoyama, Eds., Elsevier, International Congress Series 1013, 295-298
(1992). Request Paper
Skov KA .
The interaction of platinum complexes with low doses of X-rays in hypoxic cells: Possible role of crosslinks.
In: Low Dose Irradiation and Biological Defense Mechanisms, T. Sugahara, L.A. Sagan and T. Aoyama, Eds., Elsevier, International Congress Series 1013, 367-370
(1992). Request Paper
1990
Skov KA .
Toxicity of metal complexes with radiosensitizing properties.
In: NATO Advanced Research Seminar Series A198 "Selective Activation of Drugs by Redox Processes", Eds, G.E. Adams, A. Breccia, P. Wardman and E.M. Fielden, Plenum, N.Y., p. 263-273
(1990). Request Paper
1988
Chan PKL, Skov KA, James BR and Farrell NP .
Studies on ruthenium nitroimidazole complexes as radiosensitizers.
In: Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, Ed. M. Nicolini, Martinus Nijhoff, Boston, p. 638-642.
(1988). Request Paper
Skov KA, Adomat H and Farrell NP.
Effects of nickel-lapachol in hypoxic cells.
In: Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, Ed. M. Nicolini, Martinus Nijhoff, Boston, p. 733-738
(1988). Request Paper
1980
Palcic B, Skov KA and Skarsgard LD .
Effect of reducing agents on misonidazole cytotoxicity.
In: Radiation Sensitizers: Their Use in the Clinical Management of Cancer, L.W. Brady, Ed., Masson, New York, p. 438-440
(1980). Request Paper
1968
Skov K and Williams GR.
Ascorbate reduction of different forms of cytochrome c.
In: Structure and Function of Cytochromes, K. Okunuki, M. Kamen and I. Sekuzu, Eds., University of Tokyo Press, p. 349-352
(1968). Request Paper
URL: http://www.bccrc.ca/at/pubs_kskov.html
The BC Cancer Agency Research Centre is the research arm of the BC Cancer Agency (BCCA), and is supported by the BC Cancer Foundation.
This page was last modified at 3:16pm on March 28, 2006
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